Scottish academic scientist (b.1957)
For other people called Paul Sharp, see
Paul Sharp .
Paul Martin Sharp (born 1957)[ 9] professor of genetics at the University of Edinburgh , where he holds the Alan Robertson chair of genetics in the Institute of Evolutionary Biology .[ 12] [ 13] [ 14] [ 15]
Education
Sharp was educated at the University of Edinburgh where he was awarded a Bachelor of Science degree in 1979[ 9] [ 16] PhD in 1982 for research using quantitative genetics on the fruit fly Drosophila melanogaster supervised by Alan Robertson .[ 12] [ 5]
Career and research
Sharp has held academic posts at Trinity College, Dublin from 1982 to 1993,[ 4] University of Nottingham from 1993 to 2007[ 4] [ 4]
Sharp's research investigates the evolutionary origin of bacteria and viruses .[ 17] [ 18] [ 19] Plasmodium gorillas .[ 17] DNA sequence databases to gain insight into evolutionary processes. His work amplifying DNA from chimpanzee faecal samples showed that HIV type 1 was transmitted to humans from a specific chimp population in West Africa in the early 20th century. Paul went on to examine his collection of ape faecal samples for plasmodium parasites, finding a likely candidate for the form that causes malaria in humans.[ 17] [ 20]
In the eighties, Sharp collaborated with Desmond G. Higgins during the creation of CLUSTAL ,[ 10] [ 11] multiple sequence alignment programs that have become widely used and highly influential.[ 21] Biotechnology and Biological Sciences Research Council (BBSRC).[ 22] Kenneth H. Wolfe .
Awards and honours
Sharp was elected member of the European Molecular Biology Organization (EMBO) in 1992,[ 1] Society for Molecular Biology and Evolution [when? . He was elected member of the Royal Irish Academy in 1993,[ 16] Fellow of the Royal Society of Edinburgh (FRSE) in 2010[ 23] Fellow of the Royal Society (FRS) in 2013 .[ 17]
In 2024 Sharp was awarded The Darwin Medal for his work addressing the origins and evolution of HIV and the malaria parasite Plasmodium.[ 24]
Personal life
Sharps's entry in Who's Who hill walking , pteridology and, since 1967, supporting Nottingham Forest Football Club .[ 9]
References
^ a b "Paul M. Sharp University of Edinburgh, United Kingdom" . Hedelberg: EMBO. Archived from the original on 19 January 2016.^ a b Sharp, Paul M.; Li, Wen-Hsiung (1987). "The codon adaptation index-a measure of directional synonymous codon usage bias, and its potential applications" . Nucleic Acids Research . 15 (3): 1281– 1295. doi :10.1093/nar/15.3.1281 . PMC 340524 PMID 3547335 . ^ Paul M. Sharp publications indexed by Google Scholar ^ a b c d Paul Sharp's ORCID 0000-0001-9771-543X
^ a b Sharp, Paul Martin (1982). Quantitative genetics of Drosophila melanogaster : variation in male mating ability (PhD thesis). University of Edinburgh. hdl :1842/14397 . OCLC 606022632 . EThOS uk.bl.ethos.330579 . ^ Paul M. Sharp at the Mathematics Genealogy Project ^ Wolfe, Kenneth H. (1990). Rates of nucleotide substitution in higher plants and mammals OCLC 842511087 .^ "Paul M. Sharp: Computational Biology Tree" . academictree.org .^ a b c d Anon (2016). "Sharp, Prof. Paul Martin" Who's Who Oxford University Press ed.). Oxford: A & C Black. doi :10.1093/ww/9780199540884.013.271679 . (Subscription or UK public library membership required.) ^ a b Higgins, Desmond G.; Sharp, Paul M. (1988). "CLUSTAL: a package for performing multiple sequence alignment on a microcomputer". Gene . 73 (1): 237– 244. doi :10.1016/0378-1119(88)90330-7 . PMID 3243435 . ^ a b Higgins, Desmond G.; Sharp, Paul M. (1989). "Fast and sensitive multiple sequence alignments on a microcomputer". Bioinformatics . 5 (2): 151– 153. doi :10.1093/bioinformatics/5.2.151 . PMID 2720464 . ^ a b "Professor Paul M. Sharp, FRS, FRSE, MRIA: Alan Robertson Chair of Genetics" . Edinburgh: University of Edinburgh . Archived from the original on 12 April 2016.^ Sharp, P. M.; Hahn, B. H. (2011). "Origins of HIV and the AIDS Pandemic" . Cold Spring Harbor Perspectives in Medicine . 1 (1): a006841. doi :10.1101/cshperspect.a006841 . PMC 3234451 PMID 22229120 . ^ "Staff profiles: Institute of Evolutionary Biology" . Edinburgh: University of Edinburgh. Archived from the original on 17 September 2015.^ Paul M. Sharp publications from Europe PubMed Central ^ a b "Paul Martin Sharp BSc, PhD (Edin 1979, 1982). FRS, FRSE" . Dublin: Royal Irish Academy. 19 October 2015. Archived from the original on 13 April 2016.^ a b c d Anon (2013). "Professor Paul Sharp FRS" . London: Royal Society . Archived from the original on 17 November 2015. “All text published under the heading 'Biography' on Fellow profile pages is available under Creative Commons Attribution 4.0 International License .” --"Royal Society Terms, conditions and policies" . Archived from the original on 25 September 2015. Retrieved 9 March 2016 .{{cite web }}: CS1 maint: bot: original URL status unknown (link )
^ Paul M. Sharp publications indexed by the Scopus bibliographic database. (subscription required) ^ Hahn, Beatrice H.; Shaw, George M.; Cock, Kevin M. De; Sharp, Paul M. (2000). "AIDS as a Zoonosis: Scientific and Public Health Implications". Science 287 (5453): 607– 614. Bibcode :2000Sci...287..607H . doi :10.1126/science.287.5453.607 . PMID 10649986 . ^ Gao, Feng; Bailes, Elizabeth; Robertson, David L.; Chen, Yalu; Rodenburg, Cynthia M.; Michael, Scott F.; Cummins, Larry B.; Arthur, Larry O.; Peeters, Martine; Shaw, George M.; Sharp, Paul M.; Hahn, Beatrice H. (1999). "Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes" . Nature . 397 (6718): 436– 441. Bibcode :1999Natur.397..436G . doi :10.1038/17130 PMID 9989410 . S2CID 4432185 . ^ Van Noorden, R.; Maher, B.; Nuzzo, R. (2014). "The top 100 papers: Nature explores the most-cited research of all time" . Nature 514 (7524): 550– 3. doi :10.1038/514550a PMID 25355343 . ^ "UK Government grants awarded to Paul M. Sharp" . Swindon: Research Councils UK . Archived from the original on 12 April 2016.^ "Royal Society of Edinburgh Fellows as of 2016-05-13" (PDF) . Edinburgh: Royal Society of Edinburgh . Archived from the original (PDF) on 30 March 2016.^ "Darwin Medal | Royal Society" . royalsociety.org . 29 November 2024. Retrieved 11 December 2024 .
Fellows Honorary Foreign Royal
