Search Results: Dopamine system


Dopamine
Senin, 2026-08-10 20:14:31

Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic...

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Dopamine (disambiguation)
Kamis, 2026-01-08 05:19:39

Look up dopamine in Wiktionary, the free dictionary. Dopamine is a chemical naturally produced in the body. Dopamine may also refer to: Dopamine (medication)...

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Dopamine fasting
Jumat, 2026-06-12 03:54:30

Dopamine fasting is the general practice of abstaining from any impulsive and behavioral addictions in order to cope with such addictions and thus attempt...

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Dopamine receptor
Jumat, 2026-08-14 23:45:59

(dopamine receptor-interacting proteins) interactions. The neurotransmitter dopamine is the primary endogenous ligand for dopamine receptors. Dopamine...

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Dopamine agonist
Sabtu, 2026-08-22 13:12:04

A dopamine agonist is a compound that activates dopamine D2 receptors and belong to one of two different subclasses: ergoline and non-ergoline. Examples...

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Dopamine transporter
Sabtu, 2026-08-15 01:03:34

The dopamine transporter (DAT, also sodium-dependent dopamine transporter) is a membrane-spanning protein coded for in humans by the SLC6A3 gene (also...

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Dopamine reuptake inhibitor
Rabu, 2026-05-27 12:59:47

A dopamine reuptake inhibitor (DRI) is a class of drug which acts as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action...

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Dopamine antagonist
Senin, 2026-08-10 08:20:13

A dopamine antagonist, also known as an anti-dopaminergic and a dopamine receptor antagonist (DRA), is a type of drug which blocks dopamine receptors...

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Dopamine (Normani album)
Selasa, 2026-04-07 06:50:34

Dopamine is the debut solo studio album by American singer Normani. It was released on June 14, 2024, through RCA Records. The album features collaborations...

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Dopamine receptor D2
Kamis, 2026-05-14 23:38:40

Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard's lab had suggested...

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Norepinephrine–dopamine reuptake inhibitor
Jumat, 2026-04-03 03:20:43

norepinephrine–dopamine reuptake inhibitor (NDRI) is a type of drug that inhibits the reuptake of the monoamine neurotransmitters norepinephrine and dopamine and...

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Neurotransmitter
Selasa, 2026-08-11 18:51:06

Common neurotransmitters include glutamate, GABA, acetylcholine, glycine, dopamine and norepinephrine. Neurotransmitters are generally synthesized in neurons...

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Dopamine (medication)
Rabu, 2026-06-17 01:52:12

Dopamine, sold under the brand name Intropin among others, is a medication most commonly used in the treatment of very low blood pressure, a slow heart...

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Dopamine (Robyn song)
Minggu, 2026-03-29 15:06:14

"Dopamine" is a song by Swedish singer Robyn. It was released on 12 November 2025 through Konichiwa Records and Young as the lead single from her ninth...

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Dopamine beta-hydroxylase
Senin, 2026-01-26 10:08:26

Dopamine β-hydroxylase (DBH), also known as dopamine β-monooxygenase, is an enzyme (EC 1.14.17.1) that in humans is encoded by the DBH gene. Dopamine...

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Dopamine hypothesis of schizophrenia
Selasa, 2026-04-28 05:38:12

The dopamine hypothesis of schizophrenia or the dopamine hypothesis of psychosis is a model that attributes the positive symptoms of schizophrenia to a...

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Dopaminergic pathways
Selasa, 2026-06-23 05:09:24

Dopaminergic pathways (dopamine pathways, dopaminergic projections) in the human brain are involved in both physiological and behavioral processes including...

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The Dopamines
Senin, 2025-11-10 23:41:56

The Dopamines are an American punk rock band originating from Cincinnati, Ohio, formed in late 2006 by Matt Hemingway (drums), Jon Lewis (guitar, vocals)...

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Dopamine dysregulation syndrome
Senin, 2026-07-20 01:30:52

Dopamine dysregulation syndrome (DDS) is a rare dysfunction of the reward system observed in some individuals taking dopaminergic medications for an extended...

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Dopamine receptor D4
Selasa, 2026-07-07 11:21:53

The dopamine receptor D4 is a dopamine D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of DRD4 has...

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Dopamine (Børns album)
Minggu, 2025-09-14 03:37:46

Dopamine is the debut studio album by American singer-songwriter Børns, released on October 16, 2015 by Interscope Records. On August 19, 2015, Børns announced...

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Parkinson's disease
Selasa, 2026-08-18 09:14:10

processes. Parkinson's disease involves the gradual decay and loss of dopamine-producing neurons in a brain region called the substantia nigra and other...

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Dopamine (Lil Tecca album)
Jumat, 2026-08-21 14:34:26

Dopamine is the fifth studio album by the American rapper and singer Lil Tecca. It was released on June 13, 2025, through Galactic and Republic Records...

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Dopamine receptor D1
Senin, 2026-08-17 16:43:53

Dopamine receptor D1, also known as DRD1, is one of the two types of D1-like receptor family—receptors D1 and D5. It is a protein that in humans is encoded...

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Dopamine hypothesis
Senin, 2023-12-04 05:26:16

Dopamine hypothesis may refer to: Dopamine hypothesis of bipolar disorder (see Bipolar_disorder#Proposed_mechanisms) Dopamine hypothesis of schizophrenia...

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Motivation-enhancing drug
Senin, 2026-08-10 23:36:29

dopaminergic agents, for instance dopamine reuptake inhibitors (DRIs) like methylphenidate and modafinil, dopamine releasing agents (DRAs) like amphetamine...

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Dopamine releasing agent
Minggu, 2026-02-22 05:51:55

A dopamine releasing agent (DRA) is a type of drug which induces the release of dopamine in the body and/or brain. No selective DRAs are currently known...

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Levodopa
Selasa, 2026-08-11 11:32:13

of levodopa into dopamine in serotonergic neurons (which cannot re-uptake dopamine and have no proper regulatory capacity for dopamine synthesis) becoming...

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Atypical antipsychotic
Selasa, 2026-08-11 08:48:41

(AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), are a group of antipsychotic drugs (also generally...

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List of dopaminergic drugs
Senin, 2025-09-01 12:12:03

other chemicals that influence the function of the neurotransmitter dopamine. Dopamine receptors are a class of G protein-coupled receptors that are prominent...

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Dopamine therapy
Senin, 2025-09-29 07:47:41

a dopamine imbalance. Dopamine replacement therapy (DRT) is an effective treatment for patients with decreased levels of dopamine. Often dopamine antagonists...

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List of investigational Parkinson's disease drugs
Minggu, 2026-08-09 16:23:19

dopamine reuptake inhibitor (DRI) and single-photon emission-computed tomography (SPECT) enhancer [3] Apomorphine (Aporon) – non-selective dopamine receptor...

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Serotonin–norepinephrine–dopamine releasing agent
Sabtu, 2025-08-30 04:42:16

A serotonin–norepinephrine–dopamine releasing agent (SNDRA), also known as a triple releasing agent (TRA), is a type of drug which induces the release...

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Dopamine-responsive dystonia
Sabtu, 2026-08-01 14:09:52

Dopamine-responsive dystonia (DRD) also known as Segawa syndrome (SS), is a genetic movement disorder which usually manifests itself during early childhood...

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Dopamine supersensitivity psychosis
Jumat, 2026-06-05 04:08:23

Dopamine supersensitivity psychosis is a hypothesis that attempts to explain the phenomenon in which psychosis (e.g., hallucinations, delusions) occurs...

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Dopamine @ 2.22
Kamis, 2026-03-12 03:05:27

Dopamine @ 2.22 is a 2024 Indian Tamil-language film written and directed by Dhirav. The film stars himself, Vijay Duke, Vibitha Thekkepet, Nikhila Sankar...

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D1–D2 dopamine receptor heteromer
Senin, 2026-08-10 14:53:12

The D1–D2 dopamine receptor heteromer is a receptor heteromer consisting of D1 and D2 protomers. D1 and D2 receptors interact primarily through discrete...

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Serotonin–dopamine reuptake inhibitor
Sabtu, 2026-07-11 19:30:24

serotonin–dopamine reuptake inhibitor (SDRI) is a type of drug which acts as a reuptake inhibitor of the monoamine neurotransmitters serotonin and dopamine by...

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PPP1R1B
Selasa, 2026-08-11 15:57:04

Protein phosphatase 1 regulatory subunit 1B (PPP1R1B), also known as dopamine- and cAMP-regulated neuronal phosphoprotein (DARPP-32), is a protein that...

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Norepinephrine–dopamine releasing agent
Rabu, 2026-07-01 12:44:09

norepinephrine–dopamine releasing agent (NDRA) is a type of drug which induces the release of norepinephrine (and epinephrine) and dopamine in the body and/or...

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Serotonin–dopamine releasing agent
Minggu, 2025-12-21 13:33:06

A serotonin–dopamine releasing agent (SDRA) is a type of drug which induces the release of serotonin and dopamine in the body and/or brain. SDRAs are...

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Dopamine beta hydroxylase deficiency
Minggu, 2026-06-21 22:17:10

Dopamine beta (β)-hydroxylase deficiency is a human medical condition involving inadequate dopamine beta-hydroxylase. It is characterized by increased...

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Locomotor activity
Selasa, 2026-08-11 18:34:59

many sedative agents and general anesthetics. Antipsychotics, which are dopamine receptor antagonists, and many serotonergic agents, such as meta-chlorophenylpiperazine...

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Dopamine (Purple Disco Machine song)
Selasa, 2026-08-04 22:36:12

"Dopamine" is a song by German disco and house music producer and DJ Purple Disco Machine featuring Dutch singer-songwriter Eyelar, released on 27 August...

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BP1.4979
Sabtu, 2026-04-04 04:20:57

BP1.4979 is a selective dopamine D3 receptor agonist which is under development for the treatment of binge-eating disorder, obsessive–compulsive disorder...

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Dopaminergic
Kamis, 2026-08-13 05:16:10

"related to dopamine" (literally, "working on dopamine"), a common neurotransmitter. Dopaminergic substances or actions increase dopamine-related activity...

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DETQ
Jumat, 2026-08-21 02:55:18

allosteric modulator of the dopamine D1 receptor. It increases the D1 receptor-mediated response to endogenous dopamine levels, and was developed as...

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Dopamine receptor D3
Minggu, 2026-07-12 22:53:20

Dopamine receptor D3 (DRD3) is a protein belonging to the dopamine receptor family of G protein-coupled receptors. In humans, it is encoded by the DRD3...

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Catecholamine
Senin, 2026-07-27 05:16:50

to convert tyrosine serially to L-DOPA and then to dopamine. Depending on the cell type, dopamine may be further converted to norepinephrine or even further...

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ML398
Kamis, 2026-08-20 16:23:59

potent and selective dopamine D4 receptor antagonist which has been used in scientific research. It shows high affinity for the dopamine D4 receptor (Ki =...

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Dopamine receptor D5
Rabu, 2025-09-24 02:09:06

Dopamine receptor D5, also known as D1BR, is a protein that in humans is encoded by the DRD5 gene. It belongs to the D1-like receptor family along with...

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Etrabamine
Jumat, 2026-06-26 18:44:03

shows affinity for the dopamine D2 and D3 receptors (Ki = 2,620 nM and 300 nM, both for L-etrabamine). It acts as a dopamine D2 and D3 receptor agonist...

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Matsupexole
Sabtu, 2026-04-04 01:24:58

Nonproprietary Name; developmental code names AM006 and KDT-3594) is a dopamine receptor agonist which is under development for the treatment of Parkinson's...

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Aripiprazole
Selasa, 2026-08-25 04:55:14

action is as a functionally selective partial agonist at dopamine D2 receptors, stabilizing dopamine activity by enhancing signaling when levels are low and...

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Methylphenidate
Kamis, 2026-08-20 05:30:40

doses. Methylphenidate is believed to work by blocking the reuptake of dopamine and norepinephrine by neurons. It is a CNS stimulant of the phenethylamine...

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Wolfram Schultz
Senin, 2026-05-18 13:09:55

University of Cambridge known for his discovery of the neurophysiological dopamine reward signal. Schultz received his medical degree from the University...

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List of investigational attention deficit hyperactivity disorder drugs
Selasa, 2026-07-28 11:25:27

prodrug / norepinephrine–dopamine reuptake inhibitor Solriamfetol (ADX-N05, ARL-N05, JZP-110, SKL-N05; Sunosi) – norepinephrine–dopamine reuptake inhibitor...

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ENX-104
Senin, 2026-02-16 15:09:59

ENX-104, also known as deuterated nemonapride enantiomer, is a selective dopamine D2 and D3 receptor antagonist which is under development for the treatment...

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Bupropion
Minggu, 2026-08-23 05:26:54

affective disorder and to support smoking cessation. It is a norepinephrine–dopamine reuptake inhibitor (NDRI). Some evidence-based guidelines support first-line...

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Dopamine (Third Eye Blind album)
Kamis, 2026-07-02 00:48:06

Dopamine is the fifth studio album by American rock band Third Eye Blind, released on June 16, 2015. It is the band's first studio album since 2009's Ursa...

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Amphetamine
Senin, 2026-08-10 07:54:22

brain, with its most pronounced effects targeting the norepinephrine and dopamine neurotransmitter systems. At therapeutic doses, amphetamine causes emotional...

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List of investigational antipsychotics
Rabu, 2026-08-05 09:39:07

long acting injectable (mdc-TJK; TEV-749; TV-44749) – dopamine D1 receptor antagonist, dopamine D2 receptor antagonist, serotonin 5-HT2A receptor antagonist...

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Serotonin–norepinephrine–dopamine reuptake inhibitor
Minggu, 2026-08-16 13:27:12

A serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), also known as a triple reuptake inhibitor (TRI or TUI), is a type of drug that acts as...

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Nina Dopamine
Jumat, 2026-08-14 18:13:11

Nian Hu, known professionally as Nina Dopamine, is an American pop rock singer-songwriter. She graduated from Harvard University in 2018 and later entered...

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ABT-925
Selasa, 2026-06-09 05:08:11

ABT-925, also known as A-437203 or as LU-201640, is a selective dopamine D3 receptor antagonist which was under development for the treatment of schizophrenia...

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Ropinirole
Kamis, 2026-05-28 07:14:20

pregnancy and breastfeeding is of unclear safety. It is a dopamine agonist and works by triggering dopamine D2 receptors. It was approved for medical use in the...

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Neuroleptic malignant syndrome
Selasa, 2026-07-14 00:39:23

antipsychotics (neuroleptics) or other drugs that block the effects of dopamine. Symptoms include high fever, confusion, rigid muscles, variable blood-pressure...

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GSK-598809
Kamis, 2026-08-20 17:21:15

GSK-598809 is a selective dopamine D3 receptor antagonist that is or was under development for the treatment of substance-related disorders, smoking withdrawal...

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A-69024
Senin, 2026-06-15 13:16:12

A-69024 is a selective dopamine D1 receptor antagonist which was under development for the treatment of psychotic disorders but was never marketed. Its...

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Restless legs syndrome
Jumat, 2026-08-14 02:57:36

related to the neurotransmitter dopamine, and common medications for both conditions among other systems, affect dopamine levels in the brain. A 2005 study...

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Lu 38-012
Rabu, 2026-07-08 17:43:42

potent and selective dopamine D4 receptor antagonist which has been used in scientific research. It has an affinity (Ki) for the dopamine D4.2 receptor of...

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SKF-89626
Jumat, 2026-04-10 16:40:55

SKF-89626 is a highly selective full agonist of the dopamine D1 receptor of the thienopyridine family. However, the drug only weakly crosses the blood–brain...

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Disorders of diminished motivation
Rabu, 2026-05-06 23:31:11

and other activating medications, such as dopamine reuptake inhibitors, dopamine releasing agents, and dopamine receptor agonists, among others. These kinds...

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Norepinephrine–dopamine disinhibitor
Selasa, 2026-06-23 10:45:43

norepinephrine and dopamine disinhibitor (NDDI or NDD) is a drug that acts at specific sites to disinhibit downstream norepinephrine and dopamine release in the...

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3,4-Dihydroxyphenylacetaldehyde
Minggu, 2026-02-22 12:28:26

dopamine aldehyde, is a metabolite of the monoamine neurotransmitter dopamine formed by monoamine oxidase (MAO). Other metabolic pathways of dopamine...

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Ordopidine
Kamis, 2026-08-20 18:20:15

International Nonproprietary Name; developmental code ACR-325) is an atypical dopamine D2 receptor antagonist and so-called "dopaminergic stabilizer" which is...

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Adipsia
Kamis, 2026-05-07 11:35:11

have normal levels of urine osmolality as well as typical ADH activity. Dopamine, a neurotransmitter, has been linked with feeding behaviors. In an experiment...

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Nigrostriatal pathway
Minggu, 2026-05-03 02:41:36

caudate nucleus and putamen) in the forebrain. It is one of the four major dopamine pathways in the brain, and is critical in the production of movement as...

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Centanafadine
Minggu, 2026-08-23 07:24:11

is a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), with preference for norepinephrine and then dopamine over serotonin, and has stimulant...

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Dopamine-hit sites
Sabtu, 2026-08-22 05:20:04

Dopamine-hit sites are a category of websites designed to replicate the user interface and interaction patterns of potentially addictive online activities...

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Psychosis
Rabu, 2026-08-12 06:56:27

cause. Psychosis is not well-understood at the neurological level, but dopamine (along with other neurotransmitters) is known to play an important role...

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Odapipam
Kamis, 2026-06-04 09:28:58

the dopamine D1 receptor (Ki = 0.17 nM) over the dopamine D2 receptor (Ki = 942 nM). Its affinities for other dopamine receptors, such as the dopamine D5...

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Dopamine (2003 film)
Senin, 2026-04-13 07:12:50

Dopamine is a 2003 romantic comedy-drama film written and directed by Mark Decena. Rand is a computer animator, who has created an artificial intelligence...

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Dihydroergocryptine
Jumat, 2026-08-21 17:07:55

(DHEC), sold under the brand names Almirid and Cripar among others, is a dopamine agonist of the ergoline group that is used as an antiparkinson agent in...

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Effects of estrogen on schizophrenia
Minggu, 2026-08-09 22:11:12

suggest that estrogen acts as a barrier to dopamine receptors, and so may prevent the increase in dopamine found in patients with schizophrenia. However...

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List of investigational narcolepsy and hypersomnia drugs
Sabtu, 2026-08-08 08:53:48

norepinephrine–dopamine reuptake inhibitor (NDRI) – idiopathic hypersomnia [15] Serdexmethylphenidate (KP-484; KP-1077; KP-879) – norepinephrine–dopamine reuptake...

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F-17464
Rabu, 2026-06-10 18:51:02

F-17464 is a dopamine D3 receptor antagonist and serotonin 5-HT1A receptor partial agonist which was under development for the treatment of schizophrenia...

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Vesicular monoamine transporter 2
Minggu, 2026-08-16 09:56:25

protein that transports monoamines—particularly neurotransmitters such as dopamine, norepinephrine, serotonin, and histamine—from cellular cytosol into synaptic...

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Dimethocaine
Minggu, 2026-06-14 16:30:17

uptake of dopamine (DA) by blocking dopamine transporters (DAT). The dopamine transporter controls the dynamics of the neurotransmitter dopamine. This neurotransmitter...

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Methamphetamine
Selasa, 2026-08-25 02:51:25

amphetamine chemical classes and as a drug acts as a serotonin–norepinephrine–dopamine releasing agent. It is related to the other dimethylphenethylamines as...

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Motivational salience
Selasa, 2026-08-11 18:47:19

patterns in dopamine activity in response to external stimuli influence motivational behavior. Tonic dopamine refers to steady dopamine release from...

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S32504
Jumat, 2026-04-10 08:08:18

S32504 is a dopamine D2 and D3 receptor agonist which was under development for the treatment of Parkinson's disease but was never marketed. Its route...

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XC-130
Senin, 2026-02-16 10:22:35

is a dopamine receptor agonist which is under development for the treatment of Parkinson's disease. It is taken orally. The drug is a dopamine D2 receptor...

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MDMA
Minggu, 2026-08-23 06:06:37

primarily by increasing the release of the neurotransmitters serotonin, dopamine, and norepinephrine in parts of the brain. It belongs to the substituted...

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Fast-scan cyclic voltammetry
Rabu, 2026-06-03 08:31:41

noradrenaline), brain slices (5-HT, dopamine, norepinephrine) and in vivo in anesthetized or awake and behaving animals (dopamine). Further refinements of the...

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Deacetylipecoside synthase
Selasa, 2025-07-22 19:16:27

reaction deacetylipecoside + H2O ⇌ {\displaystyle \rightleftharpoons } dopamine + secologanin This enzyme belongs to the family of lyases, specifically...

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Pramipexole
Kamis, 2026-07-23 21:24:23

alone or together with levodopa. It is taken by mouth. Pramipexole is a dopamine agonist of the non-ergoline class. Pramipexole was approved for medical...

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Berupipam
Kamis, 2026-06-04 09:21:55

Nonproprietary Name; developmental code name NNC 22-0010) is a selective dopamine D1 receptor antagonist of the benzazepine group which was under development...

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Mesolimbic pathway
Selasa, 2026-01-20 23:13:08

includes the nucleus accumbens and the olfactory tubercle. The release of dopamine from the mesolimbic pathway into the nucleus accumbens regulates incentive...

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Tavapadon
Kamis, 2026-01-29 05:02:29

Tavapadon (developmental code names CVL-751, PF-06649751) is a dopamine receptor agonist which is under development for the treatment of Parkinson's disease...

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Mitchell Froom
Rabu, 2026-07-15 21:43:42

Froom has released two solo albums, Dopamine (1998) and A Thousand Days (2005). The song "Noodletown" from "Dopamine" won an Emmy when it was used as the...

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Dopamine (Mila J album)
Senin, 2026-05-11 01:09:42

Dopamine (stylised in all caps) is the debut studio album by American singer Mila J. It was released on April 7, 2017, through Silent Partner Entertainment...

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Central nervous system fatigue
Kamis, 2025-11-13 20:21:37

(but not limited to) serotonin (5-HT), noradrenaline, and dopamine. The roles of dopamine, noradrenaline, and serotonin in CNS fatigue are unclear, as...

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1Z2MAP1O
Minggu, 2026-01-11 05:21:35

serotonin and 227 nM for dopamine in Chinese hamster ovary (CHO) cells expressing the human monoamine transporters (MATs). The dopamine/serotonin ratio was...

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Dopamine transporter deficiency syndrome
Minggu, 2026-03-15 13:34:53

Dopamine transporter deficiency syndrome (DTDS), also known as infantile parkinsonism-dystonia, is a rare movement disorder that causes progressively worsening...

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Nucleus accumbens
Selasa, 2026-08-11 18:53:41

of dopamine into the Nacc via interactions with VMAT2 and TAAR1 in the axon terminal of mesolimbic dopamine neurons. Glucocorticoids and dopamine: Glucocorticoid...

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Carmoxirole
Kamis, 2026-07-30 04:08:00

International Nonproprietary Name; developmental code name EMD-45609) is a dopamine D2 receptor agonist which was developed as a potential antihypertensive...

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DA-Phen
Minggu, 2025-12-21 12:11:53

DA-Phen, also known as dopamine–phenylalanine conjugate, is a synthetic dopamine prodrug which is under preclinical evaluation. Dopamine itself is hydrophilic...

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List of antidepressants
Kamis, 2026-07-09 11:02:49

Serotonin–dopamine reuptake inhibitors include: None currently marketed Medifoxamine (Clédial, Gerdaxy) Serotonin–norepinephrine–dopamine reuptake inhibitors...

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Arvid Carlsson
Kamis, 2026-02-19 03:19:14

for his work with the neurotransmitter dopamine and its effects in Parkinson's disease. For his work on dopamine, Carlsson was awarded the Nobel Prize...

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Anna Lembke
Selasa, 2026-06-23 01:50:28

Were Duped, Patients Got Hooked, and Why It’s So Hard to Stop. Her book, Dopamine Nation: Finding Balance in the Age of Indulgence, was released in August...

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Instagram
Minggu, 2026-08-23 15:47:30

triggering dopamine surges akin to other addictive behaviors. The rapid and easily consumable nature of short-form videos can elicit high levels of dopamine; since...

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Rotigotine
Selasa, 2026-07-28 01:43:07

Rotigotine, sold under the brand name Neupro among others, is a dopamine agonist of the non-ergoline class of medications indicated for the treatment of...

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Monoamine releasing agent
Selasa, 2026-08-11 18:46:26

The monoamine neurotransmitters include serotonin, norepinephrine, and dopamine; MRAs can induce the release of one or more of these neurotransmitters...

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Glovadalen
Kamis, 2026-05-28 05:48:52

Glovadalen (developmental code name UCB-0022) is a dopamine D1 receptor positive allosteric modulator which is under development for the treatment of Parkinson's...

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Nuciferine
Selasa, 2026-08-11 05:53:46

serotonin and dopamine receptors, acting as an antagonist of some receptors and as an agonist of others, and additionally acts as a dopamine reuptake inhibitor...

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Cocaine
Rabu, 2026-08-19 11:14:46

administration. Pharmacologically, cocaine acts as a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), producing reinforcing effects such as euphoria...

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Stimulant
Jumat, 2026-08-21 00:59:36

concentrations of excitatory neurotransmitters, particularly norepinephrine and dopamine. Other stimulants work by binding to the receptors of excitatory neurotransmitters...

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SoRI-9804
Kamis, 2026-01-01 03:27:33

allosteric modulator of dopamine transporters. Unlike others in its series & traditional DRI ligands, it inhibits the release of dopamine in addition to inhibiting...

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Novelty seeking
Rabu, 2026-05-20 22:16:35

novel choice option), dopamine is directly shown to increase novelty-seeking behavior. Specifically, blockade of the dopamine transporter, causing a...

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Management of Parkinson's disease
Minggu, 2026-08-23 13:48:54

main families of drugs useful for treating motor symptoms are levodopa, dopamine agonists, and MAO-B inhibitors. The most commonly used treatment approach...

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Tuberoinfundibular pathway
Rabu, 2026-07-01 19:41:44

The tuberoinfundibular pathway refers to a population of dopamine neurons that project from the arcuate nucleus (a.k.a. the "infundibular nucleus") in...

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Adrogolide
Minggu, 2026-06-07 09:10:52

United States Adopted Name) in the case of the hydrochloride salt, is a dopamine D1-like receptor agonist which was under development for the treatment...

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Dipropyldopamine
Jumat, 2026-08-07 12:19:07

agonist of both dopamine D1-like and D2-like receptors, with much greater potency at dopamine D2 receptors than dopamine itself. Unlike dopamine, the drug lacks...

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List of modafinil analogues and derivatives
Jumat, 2026-07-31 05:00:20

derivatives of modafinil, a drug that affects dopamine levels in the brain in an unusual way (atypical dopamine reuptake inhibitor or DRI). Modafinil is a...

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Børns
Rabu, 2026-06-10 23:17:21

two on the Billboard Heatseekers chart. The Dopamine tour followed, preceding his debut studio album Dopamine in 2015. The album was a commercial success...

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Α-Methyl-p-tyrosine
Selasa, 2026-08-04 16:41:46

can increase dopamine biosynthesis; therefore an increase in pSer31 or pSer40 elevates dopamine synthesis in DA neurons. Excessive dopamine in the mesolimbic...

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ENX-105
Kamis, 2026-01-08 12:01:45

concentration) are 0.08 nM at the dopamine D2L receptor, 0.8 nM at the dopamine D2S receptor, and 3.8 nM at the dopamine D3 receptor, whereas its activational...

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Cariprazine
Minggu, 2026-08-23 16:18:45

antagonist by blocking dopamine receptors. When endogenous dopamine levels are low, cariprazine acts more as an agonist, increasing dopamine receptor activity...

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N-Arachidonoyl dopamine
Senin, 2026-07-06 10:49:12

N-Arachidonoyl dopamine (NADA) is an endocannabinoid that acts as an agonist of the CB1 receptor and the transient receptor potential V1 (TRPV1) ion channel...

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Substantia nigra
Rabu, 2026-08-12 00:36:40

a projection to the basal ganglia circuit, supplying the striatum with dopamine. The pars reticulata conveys signals from the basal ganglia to numerous...

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Bell's mania
Rabu, 2026-06-24 10:34:17

escalating dopamine transmission in the nucleus accumbens. Dopamine transporter regulates the reuptake of dopamine to keep the synaptic dopamine levels within...

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Dopexamine
Jumat, 2026-01-30 04:59:06

Dopexamine is a synthetic analogue of dopamine that is administered intravenously in hospitals to reduce exacerbations of heart failure and to treat heart...

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Sexistential
Sabtu, 2026-08-08 23:54:41

through Konichiwa Records and Young. The album was supported by singles "Dopamine", the double A-sides "Sexistential" and "Talk to Me", and "Blow My Mind"...

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Dextroamphetamine
Jumat, 2026-07-31 05:25:51

monoamine neurotransmitters (namely the serotonin, norepinephrine and dopamine transporters) either via trace amine-associated receptor 1 (TAAR1) or in...

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O,O′-Dipivaloyldopamine
Minggu, 2025-12-21 12:10:23

derivative of dopamine in which both of the hydroxyl groups have been acetylated. It was developed as a lipophilic prodrug of dopamine that would allow...

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Ilana B. Witten
Kamis, 2026-04-16 09:03:01

dopamine neuron firing and positive reinforcement in her novel rate driver lines. Witten did confirm that stimulating Ventral Tegmental Area Dopamine...

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Naxagolide
Jumat, 2026-08-21 20:19:52

known as PHNO, dopazinol, L-647339, and MK-458 among other synonyms, is a dopamine receptor agonist which was developed for the treatment of Parkinson's disease...

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3-Iodotyrosine
Rabu, 2025-12-24 12:36:45

in the synthesis of the neurotransmitter dopamine, was used to determine the effects of decreased dopamine levels in social spacing of Drosophila melanogaster...

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Dopamine hypothesis of stuttering
Sabtu, 2025-05-24 20:20:38

The dopamine hypothesis of stuttering attributes to the phenomenon of stuttering a hyperactive and disturbed dopaminergic signal transduction in the brain...

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Electric Love (song)
Senin, 2026-03-16 07:51:22

track, and later appeared as the third track on his debut studio album, Dopamine. On February 26, 2017, the song was certified Platinum by the Recording...

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Philip Seeman
Senin, 2025-10-20 00:50:23

schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors. Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He...

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Kent C. Berridge
Selasa, 2026-06-23 02:37:50

drug addiction develops from a sensitization of the mesolimbic dopamine system. Dopamine normally functions to attribute incentive salience to stimuli...

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3-Methoxytyramine
Senin, 2026-08-17 02:23:56

metabolite of the monoamine neurotransmitter dopamine. It is formed by the introduction of a methyl group to dopamine by the enzyme catechol-O-methyltransferase...

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Friday (Riton and Nightcrawlers song)
Sabtu, 2026-08-08 23:17:41

"Friday", also known as "Friday (Dopamine Re-Edit)", is a song recorded by English DJ and producer Riton and Scottish-American house music project Nightcrawlers...

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Romantic love (mental state)
Minggu, 2026-08-09 05:18:39

which produce dopamine (the other being the substantia nigra pars compacta). Projections from the VTA innervate the NAc, where dopamine activity attaches...

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Area postrema
Rabu, 2026-02-18 03:41:39

stimulate the dopamine receptors. Dopamine also manages to stimulate the area postrema, since this part of the brain contains a high density of dopamine receptors...

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Monoamine reuptake inhibitor
Minggu, 2025-12-21 13:39:01

three major monoamine neurotransmitters serotonin, norepinephrine, and dopamine by blocking the action of one or more of the respective monoamine transporters...

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PRX-14040
Jumat, 2026-08-21 03:15:53

PRX-14040 is a selective dopamine reuptake inhibitor that was developed by Prexa Pharmaceuticals. It has 28-fold selectivity for the dopamine transporter over...

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Adderall
Rabu, 2026-05-06 22:19:47

dopamine receptors typically slow timing;... Depletion of dopamine in healthy volunteers impairs timing, while amphetamine releases synaptic dopamine...

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Catecholamines up
Jumat, 2024-02-16 21:59:31

Catecholamines up (Catsup) is a dopamine regulatory membrane protein that functions as a zinc ion transmembrane transporter (orthologous to ZIP7), and...

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Modafinil
Rabu, 2026-08-12 19:48:10

understood, but modafinil acts mainly as an atypical dopamine reuptake inhibitor, increasing dopamine levels without the rapid or overt signaling seen with...

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MRZ-9547
Kamis, 2026-03-05 02:31:13

(R)-phenylpiracetam, (R)-phenotropil, or (R)-fonturacetam, is a selective dopamine reuptake inhibitor (IC50Tooltip half-maximal inhibitory concentration =...

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Benperidol
Sabtu, 2025-12-06 02:40:55

high and selective affinity for the human dopamine D2 receptor when compared with all other human dopamine receptor subtypes. This is evident from its...

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Monoamine neurotoxin
Rabu, 2026-08-19 21:35:26

signal via stimulation by monoamine neurotransmitters including serotonin, dopamine, and norepinephrine. Examples of monoamine neurotoxins include the serotonergic...

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Boys Don't Cry (Lil Tecca song)
Selasa, 2026-04-21 21:17:40

rapper Lil Tecca, released as the ninth track from his fifth studio album, Dopamine (2025). The song, a Hip-hop, rage, and Emo rap composition, was written...

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Conditioned avoidance response test
Selasa, 2025-12-23 05:50:59

antidepressant-like effects. Dopamine D2 receptor antagonists, like most classical antipsychotics, are active in the CAR test once occupancy of the dopamine D2 receptor...

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Deacetylisoipecoside synthase
Selasa, 2025-07-29 12:05:51

reaction deacetylisoipecoside + H2O ⇌ {\displaystyle \rightleftharpoons } dopamine + secologanin This enzyme belongs to the family of lyases, specifically...

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Apomorphine
Senin, 2026-07-20 11:30:52

among others, is a type of aporphine that functions as a non-selective dopamine agonist which activates both D2-like and, to a much lesser extent, D1-like...

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Ventral tegmental area
Sabtu, 2025-07-12 22:09:46

of the dopaminergic cell bodies of the mesocorticolimbic dopamine system and other dopamine pathways; it is widely implicated in the drug and natural...

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Mesdopetam
Kamis, 2026-08-20 17:23:28

Nonproprietary Name; developmental code names IRL-790, IPN60170) is a dopamine D2 and D3 receptor antagonist with preference for the D3 receptor which...

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Reward system
Minggu, 2026-08-16 09:40:17

play a factor in elevated levels of dopamine, ultimately altering the CNS (or the central nervous system). Dopamine is the chemical messenger that plays...

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(S)-norcoclaurine synthase
Sabtu, 2026-03-28 14:42:47

reaction: 4-hydroxyphenylacetaldehyde + 4-(2-aminoethyl)benzene-1,2-diol (Dopamine) ⇌ {\displaystyle \rightleftharpoons } (S)-norcoclaurine + H2O This enzyme...

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Sonepiprazole
Selasa, 2026-07-07 04:08:35

a highly selective dopamine D4 receptor antagonist of the phenylpiperazine family. The drug showed high affinity for the dopamine D4.2 receptor (Ki =...

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Neuromodulation
Rabu, 2026-06-17 02:00:52

connectivity. Major neuromodulators in the central nervous system include: dopamine, serotonin, acetylcholine, histamine, norepinephrine, nitric oxide, and...

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Phencyclidine
Jumat, 2026-07-10 02:57:35

PCP has also been shown to inhibit dopamine reuptake, and thereby leads to increased extracellular levels of dopamine and hence increased dopaminergic neurotransmission...

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Rostromedial tegmental nucleus
Selasa, 2025-11-04 11:52:01

GABAergic nucleus which functions as a "master brake" for the midbrain dopamine system. This region was discovered by the researchers, M. Barrot, J.Kaufling...

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SoRI-20041
Sabtu, 2025-12-27 20:33:20

SoRI-20041 is an "antagonist-like" allosteric modulator of amphetamine-induced dopamine release (in contrast to the related research chemicals SoRI-9804 and SoRI-20040...

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Biology of romantic love
Selasa, 2026-08-11 22:34:33

anthropology, and neuroscience. Neurochemicals and hormones, such as dopamine and oxytocin, are studied along with a variety of interrelated brain systems...

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List of 2026 albums
Selasa, 2026-08-25 10:48:10

2026. Ragusa, Paolo (August 18, 2026). "Fontaines D.C. Announce New Album Dopamine Chamber, Unveil "Marianne"". Consequence. Retrieved August 18, 2026. Suskind...

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Neural pathway
Rabu, 2026-05-27 18:54:50

behaviour. This regulation is enabled by the dopamine pathways. It has been proposed that the dopamine system of pathways is the overall organiser of...

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Pathophysiology of Parkinson's disease
Jumat, 2026-08-21 17:50:03

pathophysiology of Parkinson's disease involves the gradual degeneration of dopamine producing neurons in a brain region called the substantia nigra and other...

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Gene therapy in Parkinson's disease
Jumat, 2026-01-23 19:52:47

of the creation of new cells that produce a specific neurotransmitter (dopamine), protect the neural system, or the modification of genes that are related...

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Sexual anhedonia
Senin, 2026-05-04 07:58:58

with sexual anhedonia have a dysfunction in the release of the chemical dopamine in the nucleus accumbens, the brain's primary reward center. This part...

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3,4-Dihydroxyphenylacetic acid
Rabu, 2025-12-24 13:38:34

4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance...

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Mesostriatal system
Selasa, 2024-01-02 21:56:27

midbrain dopamine projections into the striatum and cortex. It has been described as a combination of the mesolimbic and nigrostriatal dopamine projections...

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SKF-39315
Selasa, 2025-10-14 13:22:29

the neurotransmitter dopamine. The drug shows affinities (Ki) of 12 nM for the dopamine D2 receptor and 5,200 nM for the dopamine D1 receptor. It also...

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Pertine
Kamis, 2026-04-16 09:18:27

Oxypertine is known to show high affinity for the serotonin 5-HT2 and dopamine D2 receptors (Ki = 8.6 nM and 30 nM, respectively) and to also act as a...

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Brain stimulation reward
Senin, 2026-07-13 23:40:32

structures could be rewarding as well as implicated the dopamine-containing neurons of the mesolimbic dopamine system in motivational function. The motivational...

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Extinction (psychology)
Rabu, 2026-08-12 20:16:04

quantify endogenous dopamine release. Dopamine antagonists like [11C] raclopride and [18F] fallypride can be used to study D2/D3 dopamine receptor binding...

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Lisdexamfetamine
Kamis, 2026-05-28 08:41:01

dopamine receptors typically slow timing;... Depletion of dopamine in healthy volunteers impairs timing, while amphetamine releases synaptic dopamine...

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(S)-MK-26
Jumat, 2026-08-21 03:09:39

(S)-MK-26 is an atypical dopamine reuptake inhibitor (DRI) that was derived from modafinil. It is closely related to two other modafinil analogues, (S...

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Dinoxyline
Rabu, 2025-12-24 13:22:33

for scientific research, which acts as a potent full agonist at all five dopamine receptor subtypes. Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK...

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Carbidopa
Kamis, 2026-07-23 06:11:59

peripheral nervous system, preventing the premature conversion of levodopa to dopamine outside the brain. Because carbidopa cannot cross the blood-brain barrier...

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Oxiperomide
Sabtu, 2026-01-10 21:58:50

disease who are taking dopamine agonists without increasing Parkinsonian symptoms. It does this by selectively antagonizing dopamine receptors. Further development...

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RDS03-94
Selasa, 2026-08-11 01:46:14

RDS03-94, or RDS3-094, is an atypical dopamine reuptake inhibitor that was derived from the wakefulness-promoting agent modafinil. It has substantially...

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N,N-Dimethyldopamine
Senin, 2026-06-29 02:46:53

major neurotransmitter dopamine (of which it is the N,N-dimethylated analog). Because of its structural relationship to dopamine, DMDA has been the subject...

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Catatonic depression
Selasa, 2026-06-23 00:21:14

factors. Some research suggests that disturbances in neurotransmitters like dopamine and gamma-aminobutyric acid (GABA) may contribute to the development of...

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Benserazide
Rabu, 2025-12-24 13:22:10

neurotransmitter dopamine, which is administered to increase its levels in the central nervous system. However, most levodopa is decarboxylated to dopamine before...

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SKF-81,297
Senin, 2026-02-16 10:17:07

SKF-81,297 is a dopamine D1-like receptor agonist and stimulant-like drug of the 3-benzazepine family which was under development for the treatment of...

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Monoamine transporter
Minggu, 2025-08-10 05:11:14

neurotransmitters. The three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs) and are responsible...

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PF-06412562
Rabu, 2026-07-08 12:53:52

PF-06412562, also known as CVL-562, is a moderately potent and highly selective dopamine D1 and D5 receptor partial agonist which is under development for the treatment...

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Amperozide
Selasa, 2026-08-11 01:15:25

5-HT2A receptor. It does not block dopamine receptors as with most antipsychotic drugs, but does inhibit dopamine release, and alters the firing pattern...

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CE-158
Minggu, 2025-12-21 12:52:07

CE-158 is an atypical dopamine reuptake inhibitor (DRI) that was derived from modafinil. It is often but not always referred to as the enantiopure enantiomer...

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MDO-NPA
Selasa, 2026-04-07 03:53:41

enantiomers. One of these enantiomers is active as a dopamine agonist while the other is active as a dopamine antagonist. MDO-NPA has not been developed as a...

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Schizophrenia
Minggu, 2026-08-23 08:57:23

the course of the illness, perhaps linked to the age-related decline in dopamine activity. Negative symptoms are deficits of normal emotional responses...

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Desensitization (psychology)
Senin, 2026-07-27 07:57:06

desensitization process. Dopamine desensitization (also referred to in neuroscience as dopamine receptor desensitization or dopamine receptor downregulation)...

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SB269652
Sabtu, 2026-04-04 04:23:40

SB269652 is an experimental dopamine D2 and D3 receptor negative allosteric modulator. It is of interest in the potential development of novel antipsychotics...

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Basal ganglia
Rabu, 2026-06-03 06:27:11

substantia nigra is the source of the striatal input of the neurotransmitter dopamine, which plays an important role in basal ganglia function. The subthalamic...

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RU-24213
Rabu, 2026-04-08 06:15:54

is a dopamine receptor agonist of the phenethylamine family related to dopamine. It is a selective dopamine D2-like receptor agonist...

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List of investigational antidepressants
Kamis, 2026-08-20 16:08:45

– serotonin, norepinephrine, and dopamine reuptake inhibitor Lisdexamfetamine (Vyvanse) – norepinephrine and dopamine releasing agent Lithium cocrystal...

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R-5260
Minggu, 2026-08-02 03:12:41

also related to dopamine antagonist neuroleptic drugs such as spiperone and fluspirilene, although R-5260 does not have any dopamine antagonist activity...

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3-Methoxymethcathinone
Rabu, 2025-04-09 13:05:43

cathinones, it acts as a monoamine releasing agent, including of serotonin, dopamine, and norepinephrine. However, in contrast to cathinones and amphetamines...

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Norepinephrine
Minggu, 2026-08-23 17:50:05

conversion of tyrosine to dopamine occurs predominantly in the cytoplasm, the conversion of dopamine to norepinephrine by dopamine β-monooxygenase occurs...

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Carbidopa/levodopa
Senin, 2026-06-08 04:09:48

levodopa outside the brain. In the brain, levodopa is broken down into dopamine – its active form. Carbidopa also helps prevent some of the nausea which...

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Monoaminergic activity enhancer
Senin, 2026-08-17 16:08:45

MAEs have been shown to significantly enhance nerve impulse-mediated dopamine release in the striatum, substantia nigra, and olfactory tubercle; norepinephrine...

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Dihydrexidine
Minggu, 2026-02-01 10:23:20

names IP-202 and DAR-0100) is a moderately selective full agonist at the dopamine D1 and D5 receptors. It has approximately 10-fold selectivity for D1 and...

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Dopamine Chamber
Senin, 2026-08-24 04:15:27

Dopamine Chamber is the upcoming fifth studio album by the Irish rock band Fontaines D.C., set to be released on 16 October 2026 through XL Recordings...

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Monoamine-depleting agent
Selasa, 2025-12-23 13:06:00

reversibly deplete one or more of the monoamine neurotransmitters – serotonin, dopamine, and norepinephrine. One mechanism by which these agents act is by inhibiting...

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Hypothalamic–pituitary–prolactin axis
Kamis, 2026-03-12 16:22:41

that control the secretion of prolactin from the pituitary gland include dopamine ("prolactin-inhibiting factor", or "PIF"), estradiol, progesterone, thyrotropin-releasing...

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Anissa Abi-Dargham
Jumat, 2026-06-12 13:46:49

Research, and Director of the Silvio O. Conte Center for the study of "Dopamine Dysfunction in Schizophrenia", both based at the New York State Psychiatric...

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Phenylalaninol
Sabtu, 2026-02-21 15:08:14

release is 13-fold higher than its potency in inducing dopamine release. Similarly to other dopamine releasers like amphetamine, the drug shows cocaine-like...

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Relapse
Sabtu, 2026-03-07 09:44:30

as well as those who have a mental disorder. The availability of the dopamine receptor D2 plays a role in self-administration and the reinforcing effects...

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JNJ-3792165
Jumat, 2026-08-21 03:04:14

receptor GPR139. It has been shown to modulate dopamine release in the brain via interaction with the Dopamine receptor D2, and increases the effect of morphine...

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RU-27251
Kamis, 2026-01-29 10:11:36

and dopamine receptor agonist of the partial ergoline family. Its affinity (KD) for the dopamine D2high receptor was 72 nM and for the dopamine D2low...

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3-Chlorocathinone
Selasa, 2026-06-30 21:11:07

cathinone family. It is the analogue of the antidepressant and norepinephrine–dopamine reuptake inhibitor (NDRI) bupropion in which the N-tert-butyl group has...

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Amisulpride
Selasa, 2026-07-28 18:00:19

amisulpride increases dopamine concentrations in the synapse. This increased dopamine concentration is theorized to act on dopamine D1 receptors to relieve...

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Sexual intercourse
Senin, 2026-08-24 19:18:35

disorder or a behavioral addiction. It has been linked to atypical levels of dopamine, a neurotransmitter. This behavior is characterized by a fixation on sexual...

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J. W. Kebabian
Jumat, 2025-08-22 16:58:18

subtypes of dopamine receptors. His pioneering work which was published in 1979 revolutionized the understanding of the role of dopamine receptors in...

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Before I Forget (The Kid Laroi album)
Rabu, 2026-05-27 20:10:38

Andrew Aged, Clara La San, and Lithe. The album's production was handled by Dopamine, Andrew Aged, Vegyn, Jack Karaszewski, FnZ, Auz, Khaled Rohaim, Daniel...

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Fananserin
Kamis, 2026-06-04 09:25:36

serotonin 5-HT2A receptor, and the dopamine D4 receptor, but without blocking other dopamine receptors such as the dopamine D2 receptor. It has sedative and...

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O,O′-Diacetyldopamine
Minggu, 2025-12-21 12:10:28

also known as 3,4-diacetoxyphenethylamine, is a synthetic derivative of dopamine in which both of the hydroxyl groups have been acetylated. The drug was...

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Entactogen
Rabu, 2026-08-19 00:14:54

induction of dopamine and norepinephrine and serotonin 5-HT2 receptor agonism, which contributes to their effects as well. It is thought that dopamine and norepinephrine...

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CY-208,243
Sabtu, 2026-08-22 21:02:25

CY-208,243, or CY 208-243, is a drug which acts as a dopamine agonist selective for the D1 subtype. Unlike most D1-selective agonists, it shows efficacy...

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Hypokinesia
Jumat, 2026-07-10 01:26:17

diagnosis of Parkinsonism is made. Dopamine The main neurotransmitter thought to be involved in hypokinesia is dopamine. Essential to the basal ganglionic-thalamocortical...

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Dinapsoline
Rabu, 2025-12-24 13:22:37

treatment of Parkinson's disease, that acts as a selective full agonist at the dopamine D1 receptor. Gulwadi AG, Korpinen CD, Mailman RB, Nichols DE, Sit SY, Taber...

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Striatum
Selasa, 2026-08-11 19:30:05

cholinergic interneurons themselves are affected by dopamine through D5 dopamine receptors. Dopamine also directly controls communication between cholinergic...

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JHW-007
Selasa, 2026-08-11 01:37:19

JHW-007 is a cocaine analogue and a high affinity atypical dopamine reuptake inhibitor that is being researched for the treatment of cocaine addiction...

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Quetiapine
Selasa, 2026-08-25 03:57:27

work by blocking a number of receptors, including those for serotonin and dopamine. Quetiapine was developed in 1985 and was approved for medical use in the...

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Olanzapine
Selasa, 2026-08-25 08:37:01

Although its mechanism of action is not entirely clear, it is known to block dopamine and serotonin receptors. Olanzapine was patented in 1991 and approved for...

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Phenmetrazine
Jumat, 2026-05-01 20:41:34

norepinephrine–dopamine releasing agent (NDRA), with EC50Tooltip half-maximal effective concentration values for induction of norepinephrine and dopamine release...

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Β-Carboline
Jumat, 2026-05-22 23:14:27

concentration of 1,700 nM. It is also a weak dopamine reuptake inhibitor (DRI), with an IC50 of 3,040 nM at the dopamine transporter (DAT). The drug shows weak...

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LR-1111
Rabu, 2026-03-25 19:05:32

homopiperazine (azepane) ring. LR-1111 is a dopamine reuptake inhibitor (DRI) with over 4000 times selectivity for the dopamine transporter (DAT) relative to the...

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Vanilla
Senin, 2026-08-17 16:54:13

Lysophosphatidic acid Low pH (acidic conditions) Menthol (mint) N-Arachidonoyl dopamine N-Oleoyldopamine N-Oleoylethanolamide Nonivamide (PAVA) (PAVA spray) Nordihydrocapsaicin...

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Stephanie Cragg
Selasa, 2026-08-11 19:29:20

with Prof. Mark E. Walton The Handbook of Dopamine, a defining volume capturing current understanding of dopamine biology in the brain. Addiction Neuroscience...

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Chloroethylnorapomorphine
Sabtu, 2026-08-08 23:43:38

Chloroethylnorapomorphine is a chemical once thought to be an irreversible dopamine D2 receptor antagonist; however, it was later proved to be reversible....

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Phenylacetone
Jumat, 2026-04-17 22:27:49

4-Hydroxyamphetamine has been shown to be metabolized into 4-hydroxynorephedrine by dopamine beta-hydroxylase (DBH) in vitro and it is presumed to be metabolized similarly...

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List of investigational restless legs syndrome drugs
Jumat, 2026-07-03 03:05:02

[1] BP-14979 (BP-1.4979) – dopamine D3 receptor partial agonist [2] Ropinirole transdermal (Haruropi Tape; HP-3000) – dopamine D2-like receptor agonist...

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SKF-82,958
Senin, 2026-02-16 10:17:47

958 is a synthetic compound of the 3-benzazepine family that acts as a dopamine D1 and D5 receptor full agonist. SKF-82,958 and similar D1-like-selective...

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Trazpiroben
Selasa, 2026-08-04 03:25:21

TAK-906) is a dopamine antagonist drug which was under development for the treatment of gastroparesis. It acts as a peripherally selective dopamine D2 and D3...

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Coolidge effect
Minggu, 2026-08-16 19:00:01

role of the mesolimbic dopamine system on their sexual behaviour. In their experiment, microdialysis was used to monitor dopamine efflux from the nucleus...

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Lu 35-138
Rabu, 2026-07-08 17:42:36

Lu 35-138 is a dual dopamine D4 receptor antagonist and serotonin reuptake inhibitor (SRI), among other actions, which was under development for the treatment...

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Serotonin–norepinephrine reuptake inhibitor
Senin, 2026-07-06 13:28:52

related substances were shown to slow enzymatic breakdown of serotonin, dopamine, and norepinephrine via inhibition of the enzyme monoamine oxidase. For...

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2-Fluoromethcathinone
Jumat, 2025-01-17 09:14:17

acts as a dopamine and norepinephrine releasing agent (NDRA). The drug has an EC50Tooltip half-maximal effective concentration for dopamine release of...

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Dopamine (2025 film)
Sabtu, 2026-07-18 16:03:25

Dopamine (Indonesian: Dopamin) is a 2025 Indonesian crime romance thriller film directed and written by Teddy Soeria Atmadja. The film stars real-life...

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Substituted phenethylamine
Sabtu, 2026-08-15 14:15:55

Numerous endogenous compounds – including hormones, catecholamines such as dopamine and noradrenaline, and many trace amines (e.g. adrenaline, phenethylamine...

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Caffeine dependence
Rabu, 2026-08-19 05:10:40

enhance either dopamine release or the effects of dopamine in the NAc or related structures, or because they produce effects similar to dopamine. ... Long-term...

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Raclopride
Senin, 2026-03-02 02:43:53

antagonist on D2 dopamine receptors. It has been used in trials studying Parkinson Disease. Raclopride is selective for D2 and D3 dopamine receptors. It...

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Norepinephrine releasing agent
Rabu, 2026-06-17 00:52:40

adrenergic receptor agonist class. NRAs, frequently as norepinephrine–dopamine releasing agents (NDRAs) rather than as selective NRAs, are used for a...

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L-741,626
Senin, 2024-09-09 15:13:35

626 is a drug which acts as a potent and selective antagonist for the dopamine receptor D2. It has good selectivity over the related D3 and D4 subtypes...

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Phentermine
Sabtu, 2026-08-01 03:54:04

component of the "fen-phen" combination. Phentermine is a norepinephrine and dopamine releasing agent (NDRA) and produces stimulant, rewarding, and appetite...

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Attention deficit hyperactivity disorder
Senin, 2026-08-24 13:49:15

medication. The 7 repeat variant of dopamine receptor D4 (DRD4–7R) causes increased inhibitory effects induced by dopamine and is associated with ADHD. The...

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9-Methyl-β-carboline
Minggu, 2026-04-12 02:05:25

neurons and increase gene expression of several neurotrophic factors in both dopamine-depleted and normal brain cultures. It has been proposed for further investigation...

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Oxidopamine
Minggu, 2025-12-21 13:04:13

disease. The toxin oxidopamine is an antagonist of the neurotransmitter dopamine, and is commonly used for making experimental animal models in Parkinson's...

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1-Methyl-3-propyl-4-(p-chlorophenyl)piperidine
Rabu, 2026-07-01 03:26:01

drug developed by a team led by Alan Kozikowski, which acts as a potent dopamine reuptake inhibitor, and was developed as a potential therapeutic agent...

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Ecopipam
Kamis, 2026-06-04 09:52:14

Ecopipam (development codes SCH-39166, EBS-101, and PSYRX-101) is a dopamine antagonist which is under development for the treatment of Lesch–Nyhan syndrome...

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N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
Kamis, 2026-02-05 19:12:35

N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) is a dopamine-receptor antagonist. EEDQ is also a highly specific reagent for carboxyl groups. It...

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Nicotine
Minggu, 2026-08-23 04:13:13

peripheral tissues. This results in the release of neurotransmitters such as dopamine, acetylcholine, and norepinephrine, producing effects including increased...

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Synk: Parallel Line (single album)
Kamis, 2026-08-13 08:11:26

confidence and pride, aiming to captivate listeners. The second track, "Dopamine", which performed by Giselle, was described as an R&B song that contains...

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Paroxysmal hypertension
Senin, 2025-11-17 08:47:49

entity called "pseudopheochromocytoma." This disorder is due to episodic dopamine discharge and has been observed predominantly in hypertensive women whose...

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Tardive dyskinesia
Sabtu, 2026-08-08 04:22:36

been stopped. Tardive dyskinesia occurs as a result of long-term use of dopamine-receptor-blocking medications such as antipsychotics and metoclopramide...

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Addiction-related structural neuroplasticity
Jumat, 2026-03-27 21:03:30

responsible for spreading dopamine to the whole system. The VTA is stimulated by ″rewarding experiences″. The release of dopamine by the VTA induces pleasure...

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Romergoline
Jumat, 2026-06-05 13:35:09

International Nonproprietary Name; developmental code name FCE-23884) is a dopamine receptor modulator of the ergoline family which was under development for...

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Ketamine
Senin, 2026-08-17 12:38:12

"Effects of Ketamine and Ketamine Metabolites on Evoked Striatal Dopamine Release, Dopamine Receptors, and Monoamine Transporters". The Journal of Pharmacology...

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Neuropharmacology
Senin, 2026-08-24 21:45:06

affect dopamine and its interactions in the brain. In Parkinson's disease, a disease that decreases the amount of dopamine in the brain, the dopamine precursor...

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Levodopa-induced dyskinesia
Kamis, 2026-05-14 08:38:20

Parkinson's disease (PD), dyskinesia is often the result of long-term dopamine therapy. These motor fluctuations occur in up to 80% of PD patients after...

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Hyperprolactinaemia
Selasa, 2026-08-11 23:28:12

brain chemical dopamine, which binds to dopamine receptors. Drugs that block the effects of dopamine at the pituitary or deplete dopamine stores in the...

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4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone
Sabtu, 2025-02-01 06:18:42

4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone is a dopamine transporter reuptake inhibitor used as a lead compound to find a DRI transporter...

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Azapride
Jumat, 2025-12-26 20:28:52

derivative of the dopamine antagonist clebopride synthesized in order to label dopamine receptors. It is an irreversible dopamine antagonist. Niznik...

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Catechol-O-methyltransferase
Kamis, 2026-08-20 18:22:28

several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), catechol estrogens, and various drugs...

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DPAI
Minggu, 2026-02-22 16:18:54

2-desoxo-2-ene-ropinirole, or BD-179, is a dopamine receptor agonist and partial ergoline closely related to the clinically used dopamine receptor agonist and antiparkinsonian...

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Mevidalen
Jumat, 2026-08-21 02:32:50

disease. It acts as a selective positive allosteric modulator (PAM) of the dopamine D1 receptor. The drug is orally active and crosses the blood–brain barrier...

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GBR-13119
Jumat, 2021-05-21 20:49:35

GBR-13119 is a psychostimulant and dopamine re-uptake inhibitor. Kilbourn, Michael R.; Phil S. Sherman; Teresa Pisani (1992). "Repeated reserpine administration...

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Phenylpiracetam
Sabtu, 2026-07-18 11:13:25

However, it was discovered that (R)-phenylpiracetam is a selective atypical dopamine reuptake inhibitor in 2014. In addition, phenylpiracetam interacts with...

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Bromantane
Jumat, 2026-06-12 02:21:27

the latter directly act on the dopamine transporter (DAT) to inhibit the reuptake and/or induce the release of dopamine, bromantane instead acts via indirect...

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Atomoxetine
Sabtu, 2026-08-22 00:46:58

through norepinephrine reuptake inhibition and by indirectly increasing dopamine levels in the prefrontal cortex, sharing 70–80% of the brain regions with...

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Heaven :x: Hell
Selasa, 2026-07-28 02:28:44

single, "Waiting on a Twist of Fate", was released on February 22, 2024. "Dopamine" was released as the fourth single on March 29, 2024, the same day the...

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Antipsychotic
Minggu, 2026-08-16 20:27:05

etc.). Both generations of medication block receptors in the brain for dopamine, but atypicals block serotonin receptors as well. Third-generation antipsychotics...

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Basal ganglia disease
Senin, 2026-06-15 09:39:03

neurons. This process is regulated by dopamine secreted by the striatum onto the D1 dopamine receptor on the SNc. Dopamine excites striatal neurons in the direct...

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Atherosperminine
Sabtu, 2026-04-11 16:50:38

Atherosperminine, or atherospermine, is a dopamine receptor agonist, alkaloid found in Fissistigma glaucescens and other species, and the Hofmann degradation...

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ENX-205
Senin, 2026-01-19 21:08:13

dual dopamine D2 and D3 receptor antagonist and serotonin 5-HT1A and 5-HT2A receptor agonist. The drug is about 10-fold more potent as a dopamine D2 receptor...

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Bromocriptine
Senin, 2026-07-13 05:17:27

under the brand name Parlodel among others, is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's...

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D-DOPA
Jumat, 2025-10-17 07:29:58

treatment of Parkinson's disease (PD) and dopamine-responsive dystonia (DRD) by stimulating the production of dopamine in the brain, D-DOPA is biologically...

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SDZ 208-912
Sabtu, 2026-08-22 21:00:20

affinity for the dopamine D2 receptor, α1-adrenergic receptor, and serotonin 5-HT1A receptor, as well as somewhat lower affinity for the dopamine D1 receptor...

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Tiomergine
Selasa, 2026-06-16 05:40:32

International Nonproprietary Name; developmental code name CF 25-397) is a dopamine receptor agonist of the ergoline family which was never marketed. It is...

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Chlorpromazine
Selasa, 2026-08-11 22:46:59

is not entirely clear but is believed to be related to its ability as a dopamine antagonist. It has antiserotonergic and antihistaminergic properties. Common...

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BK-NM-AMT
Minggu, 2026-02-15 12:09:11

N-dimethyl-β-ketotryptamine, as well as 3-indoylmethcathinone, is a serotonin–dopamine releasing agent (SDRA) and putative entactogen of the tryptamine, α-alkyltryptamine...

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Iodobenzamide
Rabu, 2025-12-31 01:47:08

iolopride) is a pharmaceutical drug used for diagnostic purposes. It is a dopamine antagonist and it can be used by nuclear medicine physicians as a radioactive...

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4-Methylmethylphenidate
Jumat, 2025-11-07 07:07:34

potent than methylphenidate and has relatively low efficacy at blocking dopamine reuptake despite its high binding affinity, which led to its investigation...

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(R)-MDMA
Rabu, 2026-08-19 00:20:08

serotonin 5-HT2A receptor agonist. It has substantially less or no significant dopamine-releasing activity compared to MDMA and (S)-MDMA. In preclinial studies...

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Human
Jumat, 2026-08-21 02:35:39

humans). In the emotional state of romantic love, neurochemicals such as dopamine, norepinephrine, serotonin, and oxytocin stimulate the brain's reward system...

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4-Fluoromethylphenidate
Rabu, 2025-12-31 12:25:58

as 4-FMPH and 4F-MPH) is a stimulant drug that acts as a higher potency dopamine reuptake inhibitor than the closely related methylphenidate. 4-Fluoromethylphenidate...

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Causes of schizophrenia
Selasa, 2026-08-11 17:34:18

increased presynaptic indicators of dopamine function, but no difference in the availability of dopamine transporters or dopamine D2/D3 receptors. Both studies...

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Κ-opioid receptor
Senin, 2026-08-17 05:46:15

activation elicits immediate hyperpolarization of dopamine neurons (in 1–2 min), followed by decreased dopamine release (5–10 min) and secondary effects on...

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1:59
Senin, 2026-07-20 08:21:31

26, 2024, by RCA Records as the lead single from her debut solo album, Dopamine (2024). On March 23, 2024, Normani announced on X (formerly Twitter) that...

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London
Selasa, 2026-08-25 10:41:28

19 March 2021. McQuaid, Ian (5 December 2025). "'Constant stimulation, dopamine overload': how EsDeeKid and UK underground rap exploded on a global scale"...

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CYP2D6
Selasa, 2026-08-11 22:40:50

neurosteroids, and both m-tyramine and p-tyramine which CYP2D6 metabolizes into dopamine in the brain and liver. Considerable variation exists in the efficiency...

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Cianergoline
Sabtu, 2026-08-22 21:03:33

355/1057 or as 2-cyano-3-(6-methylergolin-8β-yl)propionamide (2-CMEBP), is a dopamine receptor agonist described as an antihypertensive agent of the ergoline...

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7-Hydroxyropinirole
Senin, 2026-02-23 13:23:34

7-Hydroxyropinirole (developmental code name SK&F-89124 or SKF-89124) is a dopamine receptor agonist and active metabolite of the antiparkinsonian agent ropinirole...

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JJC8-088
Selasa, 2026-08-11 01:39:50

JJC8-088 is a dopamine reuptake inhibitor (DRI) and psychostimulant that was derived from the wakefulness-promoting agent modafinil. It has substantially...

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Homovanillic acid
Senin, 2026-06-08 22:01:27

catechol-O-methyltransferase on dopamine. Homovanillic acid is used as a reagent to detect oxidative enzymes, and is associated with dopamine levels in the brain...

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JJC8-091
Selasa, 2026-08-11 01:42:27

JJC8-091 is an atypical dopamine reuptake inhibitor (DRI) that was derived from modafinil. It is a lead compound for potential treatment of psychostimulant...

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Α-Propylphenethylamine
Minggu, 2026-05-17 13:07:56

were 2,596 nM for dopamine and >10,000 nM for serotonin. Analogues of APPEA like phenylisobutylamine (AEPEA) are norepinephrine–dopamine releasing agents...

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Metalearning (neuroscience)
Kamis, 2026-08-13 22:14:34

neurotransmitters. Dopamine is proposed to act as a "global learning" signal, critical to prediction of rewards and action reinforcement. In this way, dopamine is involved...

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Biology of human bonding
Kamis, 2026-06-25 15:27:37

offspring. Dopamine is the primary neurotransmitter of the brain's reward and motivation system, the mesolimbic pathway. Although dopamine is often portrayed...

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Mind
Rabu, 2026-08-19 22:19:15

enhance or inhibit different types of neural communication. For example, dopamine influences motivation and pleasure while serotonin affects mood and appetite...

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Putamen
Jumat, 2026-03-20 09:08:58

dopaminergic neurons, releases dopamine to the dorsal striatum, which consists of the putamen and caudate nucleus. This dopamine release is highly important...

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Compulsion loop
Kamis, 2026-08-13 08:08:53

designed to create a neurochemical reward in the user such as the release of dopamine. Compulsion loops are deliberately used in video game design as an extrinsic...

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LEK-8829
Rabu, 2026-07-15 23:14:08

(methyl and propynyl instead of diethyl). The drug acts as a dopamine D1 receptor agonist, dopamine D2 receptor antagonist, and serotonin 5-HT1A and 5-HT2A...

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Tetrabenazine
Jumat, 2026-08-07 07:39:06

medial neostriatum (i.e., dorsal striatum). Dopamine D1 receptor antagonists like ecopipam and dopamine D2 receptor antagonists like haloperidol have...

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Procedural memory
Jumat, 2026-06-12 06:07:45

its desirable effects by blocking the DRD1 dopamine receptors in the striatum, resulting in increased dopamine levels in the brain. These receptors are...

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Razpipadon
Senin, 2026-06-08 03:24:08

Razpipadon (developmental codes CVL-871, PF-06669571, and PW-0464) is a dopamine receptor agonist which is under development for the treatment of dementia-related...

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Lil Tecca
Selasa, 2026-08-25 09:57:21

(2023), was followed by his fourth and fifth albums, Plan A (2024) and Dopamine (2025), both of which continued his series of top ten debuts on the chart...

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JJC8-089
Selasa, 2026-08-11 01:41:25

JJC8-089 is a dopamine reuptake inhibitor (DRI) that was derived from modafinil and is related to JJC8-016, JJC8-088, and JJC8-091. Its affinity (Ki) for...

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MDMAR
Minggu, 2026-03-01 08:07:14

with monoamine-releasing effects. It is a potent serotonin–norepinephrine–dopamine releasing agent (SNDRA). Substituted methylenedioxyphenethylamine 2C-B-aminorex...

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Wakefulness-promoting agent
Minggu, 2026-06-14 14:16:24

including: Dopamine reuptake inhibitors like modafinil, armodafinil, mesocarb, phenylpiracetam, and vanoxerine Norepinephrine–dopamine reuptake inhibitors...

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MPTP
Minggu, 2025-12-21 13:19:54

(MAO-B) of glial cells, specifically astrocytes. MPP+ kills primarily dopamine-producing neurons in a part of the brain called the pars compacta of the...

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Lu AF35700
Senin, 2026-06-15 13:48:03

It is taken orally. The drug is a non-selective dopamine receptor antagonist, including of the dopamine D1, D2, D3, D4, and D5 receptors (Ki = 0.56 nM...

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Tiapride
Kamis, 2026-08-20 18:30:48

Tiapride is a drug that selectively blocks D2 and D3 dopamine receptors in the brain. It is used to treat a variety of neurological and psychiatric disorders...

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Armodafinil
Minggu, 2026-08-23 08:13:38

Armodafinil acts as a selective atypical dopamine reuptake inhibitor (DRI) and hence as an indirect dopamine receptor agonist. Nonetheless, other mechanisms...

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Animal models of Parkinson's disease
Minggu, 2026-08-16 14:57:28

neurons in the substantia nigra pars compacta (SNpc). The loss of the dopamine neurons in the brain, results in motor dysfunction, ultimately causing...

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1-Ethyl-β-carboline
Kamis, 2026-05-21 07:44:34

lower-potency dopamine reuptake inhibitor (DRI), with an IC50 at the dopamine transporter (DAT) of 660 nM. It has also been found to induce dopamine release...

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CHRNA6
Senin, 2026-05-18 09:24:52

nicotinic acetylcholine receptors containing α6 subunits are expressed on dopamine-releasing neurons in the midbrain. α6 nAChRs are primarily expressed in...

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JJC8-016
Selasa, 2026-08-11 01:38:35

JJC8-016 is an atypical dopamine reuptake inhibitor (DRI) derived from modafinil. It was an early lead in the development of novel modafinil analogues...

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Mesocortical pathway
Jumat, 2024-11-29 02:45:46

ventral tegmentum to the prefrontal cortex. It is one of the four major dopamine pathways in the brain. It is essential to the normal cognitive function...

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Stephan Jenkins
Selasa, 2026-08-11 07:37:13

nine more albums: Blue (1999), Out of the Vein (2003), Ursa Major (2009), Dopamine (2015), We Are Drugs (2016), Thanks for Everything (cover album) (2018)...

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Propylone
Minggu, 2026-03-01 08:31:35

specifically as a weak partial serotonin–dopamine releasing agent (SDRA) and serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI), with EC50Tooltip...

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Fallypride
Senin, 2026-06-22 23:11:06

Fallypride is a high-affinity dopamine D2/D3 receptor antagonist used in medical research, usually in the form of fallypride (18F) as a positron emission...

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A-86929
Minggu, 2026-02-01 10:27:36

A-86929 is a synthetic compound that acts as a selective dopamine receptor D1 agonist. It was developed as a possible treatment for Parkinson's disease...

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Punding
Senin, 2026-07-20 01:33:24

point of violence. Punding has been linked primarily to an imbalance in dopamine D1 receptor and D2 receptors activation within the cortico-basal-ganglia-thalamo-cortical...

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Delusional parasitosis
Senin, 2026-04-06 10:54:37

precise cause is unknown, but is thought to be related to dysfunctional dopamine transmission in the brain similar to other psychotic disorders. Diagnosis...

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Rs1800955
Jumat, 2025-06-27 04:57:02

promoter region of the DRD4 gene. This gene codes for the dopamine receptor D4. Due to the dopamine hypothesis of schizophrenia, the SNP has been investigated...

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A-68930
Jumat, 2025-12-26 14:08:02

A-68930 is a synthetic compound that acts as a selective dopamine receptor D1 agonist. It is orally active and has antidepressant and anorectic effects...

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Seridopidine
Kamis, 2026-08-20 18:22:36

International Nonproprietary Name; developmental code name ACR343) is a dopamine D2 receptor modulator and so-called "dopaminergic stabilizer" which is...

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LY-116467
Sabtu, 2026-08-22 20:56:48

6-methylpergolide, or 6-methyl-8β-((methylthio)methyl)ergoline, is a dopamine receptor agonist of the ergoline family which was never marketed. It is...

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Borax combo
Jumat, 2026-07-24 11:42:15

and dopamine release, serotonergic psychedelics (i.e., serotonin 5-HT2 receptor agonists) have been found to augment MDMA-induced striatal dopamine release...

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Talk to Me (Robyn song)
Senin, 2026-08-17 10:47:02

Holter Robyn Producers Klas Åhlund Oscar Holter Robyn singles chronology "Dopamine" (2025) "Talk to Me" / "Sexistential" (2026) "Blow My Mind" (2026) Music...

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Wing (beatboxer)
Selasa, 2026-08-25 12:44:12

developed his skills through self-practice and online content. His track "Dopamine" attracted tens of millions of views online, contributing to his growing...

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Monooxygenase DBH-like 1
Rabu, 2025-07-30 18:14:47

features of dopamine beta-monooxygenase DBH. Since Peptidylglycine alpha-hydroxylating monooxygenase (PHM; EC 1.14.17.3) is homologous to dopamine beta-monooxygenase...

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Mamihlapinatapai (EP)
Sabtu, 2026-08-08 11:08:52

Jang, Eun-ji (April 22, 2026). '도파민 자극하는 비트' 아일릿, 30일 컴백 앞두고 하라메 공개 ['Dopamine-Stimulating Beat' Illit Unveils Highlights Ahead of Comeback on the 30th]...

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C957T
Selasa, 2025-12-02 07:01:30

RNA. 957T messenger RNA is less stable and more prone to degradation. Dopamine D2 receptor expression is increased among individuals who carry the 957T...

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Norepinephrine transporter
Sabtu, 2026-06-20 07:13:22

which is also known as noradrenaline. NET can also reuptake extracellular dopamine (DA). The reuptake of these two neurotransmitters is essential in regulating...

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Levosulpiride
Selasa, 2026-02-17 23:47:15

Levosulpiride, sold under the brand names Dislep and Sulpepta among others, is a dopamine antagonist medication which is used in the treatment of psychotic disorders...

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Temporal difference learning
Minggu, 2026-06-28 05:23:48

stimulus with the future reward. Dopamine cells appear to behave in a similar manner. In one experiment measurements of dopamine cells were made while training...

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Monoamine neurotransmitter
Selasa, 2026-08-11 18:46:24

aromatic ring by a two-carbon chain (such as -CH2-CH2-). Examples are dopamine, norepinephrine and serotonin. All monoamines are derived from aromatic...

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Eticlopride
Jumat, 2026-03-20 16:28:15

Eticlopride is a selective dopamine antagonist that acts on D2 dopamine receptor. It is primarily used in pharmacological research. "Eticlopride hydrochloride"...

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Toludesvenlafaxine
Selasa, 2025-12-23 12:50:03

other countries like the United States. It is a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) and was developed by Luye Pharma Group. Toludesvenlafaxine...

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List of adrenergic drugs
Rabu, 2024-03-27 21:32:32

(adrenaline). Amidephrine Anisodamine Anisodine Cirazoline Dipivefrine Dopamine Ephedrine Epinephrine (adrenaline) Etilefrine Ethylnorepinephrine 5-Fluoronorepinephrine...

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Para-Methoxymethamphetamine
Kamis, 2026-05-21 01:00:40

and 1,000 nM for dopamine, whereas for (R)-PMMA, they were 134 nM for serotonin, >14,000 nM for norepinephrine, and 1,600 nM for dopamine. Hence, PMMA appears...

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Nolomirole
Selasa, 2025-11-18 10:01:19

also known as 5,6-diisobutyryloxy-N-methyl-2-aminotetralin, is a dual dopamine D2 and α2-adrenergic receptor agonist which was under development for the...

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Indirect agonist
Selasa, 2025-06-24 16:20:58

indirect agonist of dopamine receptors. Cocaine binds the dopamine transporter (DAT), blocking the protein's ability to uptake dopamine from the synaptic...

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4-Hydroxy-3-methoxyamphetamine
Sabtu, 2026-02-21 09:03:07

has been found to induce the release of serotonin, norepinephrine, and dopamine with EC50Tooltip half-maximal effective concentration values of 897 nM...

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Doxanthrine
Rabu, 2025-12-24 13:22:28

synthetic compound which is a potent and selective full agonist for the dopamine D1 receptor. Doxanthrine has been shown to be orally active in producing...

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Emetine
Jumat, 2025-12-26 13:23:16

emetine come from two main biosynthesis pathways: the biosynthesis of dopamine from L-tyrosine and the biosynthesis of secologanin from geranyl diphosphate...

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LSD
Selasa, 2026-08-25 08:18:30

receptors, especially the serotonin 5-HT2A receptor, and to a lesser extent dopamine and adrenergic receptors. Neuroimaging studies indicate that LSD reduces...

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Ninety One (group)
Minggu, 2026-08-23 23:15:00

2018 Ninety One released "E.Yeah", the lead single from their album "Dopamine", quickly followed by "All I need" released on August 8. The third song...

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Perception
Jumat, 2026-08-21 17:36:38

dopamine receptors typically slow timing;... Depletion of dopamine in healthy volunteers impairs timing, while amphetamine releases synaptic dopamine...

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Management of attention deficit hyperactivity disorder
Minggu, 2026-08-23 18:11:43

treat ADHD raise the extracellular concentrations of the neurotransmitters dopamine and norepinephrine, which increases cellular communication between neurons...

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Schizotypal personality disorder
Selasa, 2026-08-25 01:40:44

be associated with schizotypal personality disorder. These genes affect dopamine production in the brain, a neurochemical thought to be associated with...

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Hemiballismus
Senin, 2025-10-27 22:44:17

most standard type of drug to use is an antidopaminergic drug. Blocking dopamine is effective in about ninety percent of patients. Perphenazine, pimozide...

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Normani
Jumat, 2026-08-21 03:46:53

the music video for Cardi B's 2020 single "WAP". Her debut studio album, Dopamine (2024), was led by the top 20 single "Wild Side" (featuring Cardi B). Normani...

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Curiosity
Rabu, 2026-07-08 22:27:26

brain that account for[clarification needed] dopamine activation. The use of these pathways, and dopamine activation, may be how the brain assigns value...

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CTDP-32476
Minggu, 2026-04-26 09:10:14

CTDP-32476 is an atypical, highly potent dopamine reuptake inhibitor investigated as a potential pharmacotherapy for cocaine addiction. Unlike cocaine...

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TAAR1
Kamis, 2026-06-25 22:58:54

concentrations. TAAR1 plays a significant role in regulating neurotransmission in dopamine, norepinephrine, and serotonin neurons in the CNS; it also affects immune...

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Cerebral dopamine neurotrophic factor
Sabtu, 2025-07-19 12:23:01

Cerebral dopamine neurotrophic factor also known as ARMET-like protein 1 is a protein that in humans is encoded by the CDNF gene. In preclinical models...

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SB-277,011-A
Minggu, 2025-12-21 14:15:40

SB-277,011A is a drug which acts as a potent and selective dopamine D3 receptor antagonist, which is around 80–100 times selective for D3 over D2, and...

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LBT-3627
Sabtu, 2024-07-20 01:01:27

immune cells in cases of neurodegenerative disease such that they protect dopamine-producing cells rather than attack them. The drug is currently being studied...

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Draquinolol
Sabtu, 2026-01-03 01:54:12

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Risperidone
Selasa, 2026-08-11 08:51:05

is not entirely clear, but is believed to be related to its action as a dopamine and serotonin antagonist. Study of risperidone began in the late 1980s...

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Sertraline
Jumat, 2026-08-21 02:15:16

Sertraline also shows relatively high activity as an inhibitor of the dopamine transporter (DAT) occupying ~20% of DAT receptors at doses 200mg and above...

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Adrenal medulla
Jumat, 2026-04-24 14:35:53

epinephrine (adrenaline), norepinephrine (noradrenaline), and a small amount of dopamine, in response to stimulation by sympathetic preganglionic neurons. The adrenal...

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Diphenidine
Jumat, 2026-06-12 20:09:05

Since diphenidine's emergence in 2013, vendors have claimed it acts on the dopamine transporter, but supporting data only became available in 2016. While diphenidine...

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CHF-1024
Selasa, 2025-11-18 10:02:57

CHF-1024, also known as 5,6-dihydroxy-2-methylaminotetralin, is a dopamine D2 receptor agonist and α2-adrenergic receptor agonist of the 2-aminotetralin...

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Mammal
Minggu, 2026-08-16 09:19:30

Sivakumar N, Ahn JS, Corpuz TV, Berke JD, Kreitzer AC, Knight ZA (July 2022). "Dopamine subsystems that track internal states". Nature. 608 (7922): 374–380. Bibcode:2022Natur...

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Dyskinesia
Selasa, 2026-06-23 13:28:09

Dopamine-depleting agents like tetrabenazine, deutetrabenazine, and valbenazine are used to treat tardive dyskinesia. Akathisia Akinesia Dopamine Hemiballismus...

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Dog
Selasa, 2026-08-25 05:30:59

attention deficit hyperactivity disorder-like showed lower serotonin and dopamine concentrations. A similar study claims that hyperactivity is more common...

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Girls Reverse
Kamis, 2026-07-30 20:01:26

KimSerena (김세레나) Rose (로즈) JipSunHui (집순희) Ruby (루비) Zzaru (짜루) Sera (세라) Dopamine (도파민) Barim (바림) Nikena (니케나) Cheer (치어) Nemo (니모) Catherine (캐서린) Sundaenaejang...

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Norepinephrine reuptake inhibitor
Rabu, 2026-06-17 02:23:23

and methylphenidate possess NRI activity, though NRIs without combined dopamine reuptake inhibitor (DRI) properties are not significantly rewarding and...

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MRS7292
Rabu, 2025-12-31 18:28:43

activates the adenosine A3 receptor with moderate affinity and also inhibits a dopamine reuptake. This combination of mechanisms has been observed in the same...

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Substituted naphthylethylamine
Sabtu, 2026-02-21 14:53:30

PMID 23072836. Blough B (July 2008). "Dopamine-releasing agents" (PDF). In Trudell ML, Izenwasser S (eds.). Dopamine Transporters: Chemistry, Biology and...

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Candy Paint (Normani song)
Selasa, 2026-04-28 10:59:55

Dopamine (2024). On May 6, 2024, Normani announced that her single "Candy Paint" would serve as the second single from her debut solo album Dopamine (2024)...

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Para-Methylphenylpiperazine
Rabu, 2026-07-01 00:33:45

case of norepinephrine and dopamine (EC50 = >10,000 nM and >20,000 nM, respectively). It shows very low potency as a dopamine reuptake inhibitor, with an...

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Flupentixol/melitracen
Kamis, 2026-08-20 16:04:03

used to treat mild to moderate mental disorders. Flupentixol acts as a dopamine 1 and 2 receptor antagonist and melitracen acts in similar way to other...

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ATC code N04
Senin, 2025-12-22 13:29:09

v t e Dopamine receptor modulators D1-like Agonists Benzazepines: 6-Br-APB Fenoldopam SKF-38,393 SKF-77,434 SKF-81,297 SKF-82,958 SKF-83,959 Trepipam Zelandopam...

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4-Methylmethamphetamine
Jumat, 2026-05-15 01:55:56

drug of the amphetamine family. It acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA). The drug is the β-diketone analogue of mephedrone...

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Ondansetron
Kamis, 2026-08-20 03:56:49

a serotonin 5-HT3 receptor antagonist. It does not have any effect on dopamine receptors or muscarinic acetylcholine receptor and therefore does not cause...

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SB-242084
Jumat, 2026-06-26 03:20:19

effects in rodents, and enhances dopamine signalling in the limbic system, as well as having complex effects on the dopamine release produced by cocaine,...

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Biology of depression
Minggu, 2026-08-16 15:13:27

supporting the role of dopamine in depression is the consistent finding of decreased cerebrospinal fluid and jugular metabolites of dopamine, as well as post...

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Sympathomimetic drug
Rabu, 2026-06-17 02:24:41

catecholamines (i.e., epinephrine [adrenaline], norepinephrine [noradrenaline], and dopamine), which function as both neurotransmitters and hormones. Sympathomimetic...

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Jonathan Sackner-Bernstein
Jumat, 2026-05-29 07:43:06

amount of dopamine free in the cytosol of the dopaminergic neurons in people with Parkinson's. While confirming that tissue levels of dopamine are markedly...

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Scutellaria lateriflora
Selasa, 2026-06-23 14:36:26

Scutellaria lateriflora, (commonly "blue skullcap", "mad dog skullcap", "American skullcap", "side-flowering skullcap", etc.) is a hardy perennial herb...

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GBR-12935
Rabu, 2025-12-24 14:06:49

GBR-12935 is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form...

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Dark Thoughts (Lil Tecca song)
Sabtu, 2026-06-27 08:00:42

through Republic Records, as the lead single of his fifth studio album, Dopamine. The song was written by Tecca and was produced by the Danish producer...

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Anxiolytic
Kamis, 2026-06-25 14:30:34

which may be mediated by neurotransmitters like norepinephrine, serotonin, dopamine, and gamma-aminobutyric acid (GABA) in the central nervous system. Anti-anxiety...

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Difluoropine
Selasa, 2026-08-11 01:32:54

acts as a potent and selective dopamine reuptake inhibitor. Difluoropine is unique among the tropane-derived dopamine reuptake inhibitors in that the...

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Alexander Cools
Jumat, 2026-01-30 01:28:30

different types of dopamine receptors, an essentially correct claim that initially was generally dismissed. Besides his work on dopamine, Cools is mostly...

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Terry Earl Robinson
Senin, 2026-08-24 19:24:58

reported that complete dopamine depletions had no effect on rats' hedonic reactions to tastes, leading to the hypothesis that dopamine mediates motivation...

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Meclizine
Selasa, 2026-07-21 12:28:04

vestibular response intact. Meclizine also has been reported to be a weak dopamine antagonist at D1-like and D2-like receptors[citation needed] but it does...

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Promethazine
Jumat, 2026-07-24 04:12:49

Tardive dyskinesia, pseudoparkinsonism, acute dystonia (effects due to dopamine D2 receptor antagonism) Confusion in the elderly Drowsiness, dizziness...

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The Eras Tour
Sabtu, 2026-08-22 17:36:13

(June 8, 2024). "Taylor Swift Eras Tour review, Edinburgh: Like mainlining dopamine for three hours straight". The Independent. Archived from the original...

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Agomelatine
Selasa, 2026-07-28 12:11:52

norepinephrine and dopamine levels in the frontal cortex with agomelatine, the drug has sometimes been referred to as a norepinephrine–dopamine disinhibitor...

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Iprocrolol
Selasa, 2026-03-03 12:29:11

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Serotonin reuptake inhibitor
Minggu, 2026-06-07 22:05:57

type of monoamine reuptake inhibitor (MRI); other types of MRIs include dopamine reuptake inhibitors and norepinephrine reuptake inhibitors. SRIs are not...

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Psychopharmacology
Senin, 2026-08-10 14:25:26

postsynaptic dopamine receptor blockers (dopamine antagonists). For an antipsychotic to be effective, it generally requires a dopamine antagonism of...

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Aromatic L-amino acid decarboxylase inhibitor
Rabu, 2025-12-24 13:21:25

a medication of type enzyme inhibitor which inhibits the synthesis of dopamine by the enzyme aromatic L-amino acid decarboxylase (AADC, AAAD, or DOPA...

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Blinking
Rabu, 2026-08-05 23:00:17

pathways dopamine production in the striatum is associated with a higher rate of spontaneous eye blinking. Conditions in which there is reduced dopamine availability...

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SKF-38,393
Senin, 2026-02-16 10:17:16

synthetic compound of the 3-benzazepine family which acts as a selective dopamine D1 and D5 receptor partial agonist. It has stimulant and anorectic effects...

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Hypergraphia
Senin, 2026-08-24 10:38:59

in brain networks utilizing one of the body's neurotransmitters, dopamine. Dopamine has been known to decrease latent inhibition, which causes a decrease...

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PC12 cell line
Senin, 2026-07-20 04:52:23

of neurotransmitter released. The vesicles hold catecholamines, mostly dopamine, but also limited amount of norepinephrine, and release of these neurotransmitters...

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Proterguride
Sabtu, 2026-08-22 20:59:48

also known as 6-propylterguride or 6-propyl-9,10-dihydrolisuride, is a dopamine agonist of the ergoline family described as a prolactin inhibitor and antiparkinsonian...

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Peter Kalivas
Selasa, 2026-06-30 21:39:47

University in Nairobi. Kalivas has contributed to neuroscience by investigating dopamine regulation, behavioral sensitization to addictive drugs, neurocircuits...

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Mila J
Selasa, 2026-07-07 00:06:31

while signed to them. In 2017, she released her official debut album, Dopamine. Mila is now an independent artist. Jamila was born and raised in Los Angeles...

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Docarpamine
Minggu, 2025-12-21 12:12:00

Accepted Name), sold under the brand name Tanadopa, is an orally active dopamine prodrug which is marketed in Japan for the treatment of acute cardiac insufficiency...

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Dehydrocorybulbine
Sabtu, 2026-01-03 05:10:17

inflammatory pain. Its primary analgesic mechanism is antagonism of the dopamine D2 receptor (D2R). Unlike opioid analgesics, preclinical studies found...

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3-Methylmethcathinone
Selasa, 2026-08-25 03:28:15

transporters in the brain) that potently releases and inhibits the reuptake of dopamine and norepinephrine, as well as displaying moderate serotonin releasing...

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Voxergolide
Jumat, 2026-04-10 08:04:44

RU-41656), also known as 6-methyl-8-[(methylthio)methyl]-9-oxaergoline, is a dopamine receptor agonist of the 9-oxaergoline family described as an anti-anoxic...

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Cathinone
Rabu, 2026-08-12 18:04:47

of a dopamine receptor antagonist. The antagonist prevents synaptic dopamine released by cathinone from exerting its effect by binding to dopamine receptors...

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Deep brain stimulation
Senin, 2026-08-24 00:24:21

infusions of intestinal dopamine, apomorphine, and medical therapy. The analysis was significantly limited because it followed dopamine prospectively only...

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Pharmacology of selegiline
Senin, 2026-05-25 10:12:09

increased levels of dopamine and β-phenethylamine, whereas MAO-A inhibition results in increased levels of serotonin, norepinephrine, and dopamine. Selegiline...

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Idiotopes
Jumat, 2025-09-05 23:27:03

Segre, Mariangela (July 2000). "Dopamine uptake by mouse neuroblastoma N1E-115 cells stably expressing human dopamine transporter is differentially inhibited...

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Euphoria
Sabtu, 2026-06-27 09:15:45

study from January 2019 that assessed the effect of a dopamine precursor (levodopa), dopamine antagonist (risperidone), and a placebo on reward responses...

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N-Methylnorsalsolinol
Selasa, 2026-04-28 18:42:53

neurotoxin N-methynorsalsolinol is carried out by enzymatic condensation of dopamine into salsolinol with its subsequent methylation under the action of neutral...

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Vanoxerine
Selasa, 2026-06-02 14:50:11

derivative which has multiple pharmacological activities including acting as an dopamine reuptake inhibitor, serotonin transporter inhibitor, and as a blocker of...

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PD-128,907
Jumat, 2026-04-10 06:23:43

scientific research which acts as a potent and selective agonist for the dopamine D2 and D3 receptors. It is used for studying the role of these receptors...

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Cocaethylene
Selasa, 2026-06-30 13:53:40

effects were identified in 1989. It acts as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), with stimulant and euphoriant properties. Cocaethylene...

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Sodium channel opener
Kamis, 2025-10-02 00:12:17

Norepinephrine reuptake inhibitor (NRI) Dopaminergic Dopamine receptor agonist Dopamine receptor antagonist Dopamine reuptake inhibitor (DRI) Histaminergic Histamine...

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CamelPhat
Sabtu, 2026-05-30 01:19:56

Dance Club Songs chart and No. 3 on the Dance Mix/Show Airplay chart. "Dopamine Machine" did not enter Flanders Ultratop 50, but did register on Ultratip...

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Colterol
Minggu, 2025-12-21 15:35:07

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Γ-Hydroxybutyric acid
Sabtu, 2026-08-22 03:09:55

effect on dopamine release is biphasic. Low concentrations stimulate dopamine release via the GHB receptor. Higher concentrations inhibit dopamine release...

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Prolactin
Minggu, 2026-08-16 09:36:03

tuberoinfundibulum (TIDA) neurons of the arcuate nucleus that secrete dopamine (a.k.a. prolactin inhibitory hormone) to act on the D2 receptors of lactotrophs...

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Exaprolol
Rabu, 2026-06-03 13:00:49

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Tretoquinol
Minggu, 2026-08-23 20:26:26

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Belgian Shepherd
Selasa, 2026-08-11 22:32:21

have been associated with rage syndrome. A genetic polymorphism in the dopamine transporter gene has been linked to rage syndrome, and dogs at risk of...

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Benocyclidine
Selasa, 2026-08-25 06:43:31

colleagues at Duke University in 1997. It acts as a potent and selective dopamine reuptake inhibitor (DRI) and a psychostimulant. Unlike related compounds...

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Carvotroline
Senin, 2026-04-13 17:55:48

International Nonproprietary Name; developmental code name WY-47791) is a dopamine D2 receptor antagonist and serotonin 5-HT2A receptor antagonist which was...

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Esmodafinil
Selasa, 2026-08-11 16:51:46

obstructive sleep apnea. Esmodafinil has about 3-fold lower affinity for the dopamine transporter (DAT) compared to armodafinil or modafinil (Ki = 780 nM, 2...

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Reserpine
Minggu, 2026-08-23 20:43:24

antipsychotics, so that more refractory patients get dopamine blockade from the other antipsychotic, and dopamine depletion from reserpine. Doses for this kind...

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Bita Moghaddam
Selasa, 2026-08-11 06:28:40

in the field, how to build and apply electroanalytical tools to study dopamine. During her PhD, Moghaddam worked on improving graphite electrodes for...

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Levoamphetamine
Selasa, 2026-08-18 05:00:05

releasing agent of the monoamine neurotransmitters norepinephrine and dopamine. It is similar to dextroamphetamine in its ability to release norepinephrine...

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EPPTB
Kamis, 2026-08-20 04:24:58

electrically evoked dopamine release in nucleus accumbens (NAcc) but not dorsal striatum (DStr) slices ex vivo. However, despite the increased dopamine neuron firing...

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Atypical antidepressant
Minggu, 2026-07-26 03:42:25

inhibitors Atomoxetine Reboxetine Viloxazine NDRIsTooltip Norepinephrine–dopamine reuptake inhibitors Amineptine‡ Bupropion Nomifensine‡ NaSSAsTooltip Noradrenergic...

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Libido
Minggu, 2026-06-07 22:32:00

in relation to sexuality, these are mainly testosterone, oestrogen and dopamine. Sigmund Freud defined libido as "the energy, regarded as a quantitative...

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7-APBT
Selasa, 2025-11-18 07:14:16

It acts specifically as a fairly well-balanced serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC50Tooltip half-maximal effective concentration...

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Fusiform gyrus
Sabtu, 2026-04-18 06:38:15

possibility that higher availability of dopamine D1 receptor may underlie better performance in face recognition task. Dopamine is known to be related to the reward...

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Levomethamphetamine
Rabu, 2026-07-01 22:21:33

balanced releasers of dopamine and norepinephrine in vitro, levomethamphetamine is about 15- to 20-fold less potent in inducing dopamine release relative to...

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Peripherally selective drug
Rabu, 2026-05-27 13:22:17

pump inhibitor Docarpamine – a dopamine prodrug and non-selective dopamine receptor agonist Domperidone – a dopamine D2 receptor antagonist used as an...

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In the Whale
Rabu, 2025-09-24 09:26:37

Dopamine’s first weeks sales made it on to the Billboard Heatseekers, Independent Albums and Heatseekers Mountain (#1) charts. During the Dopamine release...

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Deoxyepinephrine
Minggu, 2026-06-28 02:45:02

product that is structurally related to the important neurotransmitters dopamine and epinephrine. All three of these compounds also belong to the catecholamine...

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Akinetic mutism
Minggu, 2026-08-02 16:21:40

nigrostriatal pathway, which transmits dopamine. Some patients with akinetic mutism have shown to improve with levodopa or dopamine agonist therapy, or by increasing...

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Phenylpropanolamine
Selasa, 2026-08-11 11:12:43

primarily as a selective norepinephrine releasing agent. It also acts as a dopamine releasing agent with around 10-fold lower potency. The stereoisomers of...

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Obsessive–compulsive disorder
Jumat, 2026-08-14 23:51:23

cortico-striato-thalamo-cortical circuits and dysregulation of serotonin, dopamine, and glutamate. OCD is associated with a general increase in suicidality...

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Midbrain tegmentum
Kamis, 2026-03-26 15:58:29

produce and heighten dopamine activity and subsequently prompt individuals to crave drugs. Moreover, excessive mesolimbic dopamine activity plays a role...

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Fenoldopam
Jumat, 2025-11-28 05:58:47

promotes sodium excretion via specific dopamine receptors along the nephron. The renal effect of fenoldopam and dopamine may involve physiological antagonism...

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B52 (medical treatment)
Minggu, 2026-08-23 16:47:04

is used to treat agitation. Haloperidol is included because it blocks dopamine receptors, which may relieve agitation. Lorazepam is included because it...

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1-Naphthylaminopropane
Sabtu, 2026-02-21 14:49:14

methylnaphthylaminopropane (MNAP) are known to be potent serotonin–norepinephrine–dopamine releasing agents (SNDRAs) and/or serotonin receptor agonists, whereas 1-NAP...

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Phenylpropylaminopentane
Senin, 2026-08-03 13:11:19

enhances the nerve impulse propagation-mediated release of norepinephrine and dopamine. It produces psychostimulant-like effects in animals. In 2025, it was discovered...

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2-APBT
Selasa, 2025-11-18 07:16:08

It acts specifically as a fairly well-balanced serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC50Tooltip half-maximal effective concentration...

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Afurolol
Rabu, 2025-12-24 12:07:18

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Ersentilide
Selasa, 2025-12-30 20:15:16

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Enteric nervous system
Selasa, 2026-08-18 21:25:31

system (CNS), including acetylcholine, dopamine, and serotonin. The large presence of serotonin and dopamine in the intestines are key areas of research...

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Lithium (medication)
Jumat, 2026-08-21 18:28:03

neurotransmission of dopamine that causes a secondary homeostatic down-regulation, resulting in decreased neurotransmission of dopamine, which can cause depression...

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Dextromethorphan/bupropion
Rabu, 2026-08-12 14:40:05

inhibitor, among other actions, while bupropion acts as a norepinephrine–dopamine reuptake inhibitor and nicotinic acetylcholine receptor negative allosteric...

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HDMP-28
Selasa, 2026-07-28 11:39:15

(Ritalin), but with the benzene ring replaced by naphthalene. It is a potent dopamine reuptake inhibitor, with several times the potency of methylphenidate and...

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2-Chloro-2-phenylethylamine
Senin, 2026-04-20 14:10:24

β-chlorophenethylamine, is an irreversible inhibitor or suicidal inhibitor of the enzyme dopamine-beta-monooxygenase, a derivative of phenylethylamine in which the hydrogen...

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Metipranolol
Sabtu, 2026-01-10 19:21:21

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Methyldopa
Selasa, 2026-06-23 20:28:55

affects norepinephrine (noradrenaline) synthesis by way of inhibiting dopamine synthesis. Methyldopa acts on alpha-2 adrenergic receptors, which are found...

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Mazapertine
Jumat, 2025-12-26 10:29:23

never marketed. It exerts its pharmacological effect through affinity for dopamine D2, serotonin 5-HT1A, and α1-adrenergic receptors. Mazapertine is safe...

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Fenfluramine/phentermine
Selasa, 2026-05-26 07:32:56

releasing agent. Phentermine also induces the release of serotonin and dopamine, although to a far lesser extent than it induces the release of norepinephrine...

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Latent inhibition
Rabu, 2026-05-20 22:23:50

that dopamine agonists and antagonists modulate LI in rats and in normal humans. Dopamine agonists, such as amphetamines, abolish LI whereas dopamine antagonists...

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4-APBT
Selasa, 2025-11-18 07:15:41

It acts specifically as a fairly well-balanced serotonin–norepinephrine–dopamine releasing agent (SNDRA), with EC50Tooltip half-maximal effective concentration...

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MS-377
Senin, 2026-07-06 10:44:35

selectively at the sigma-1 receptor as an antagonist. It does not act on dopamine or serotonin receptors unlike most anti-psychotics. Tests have shown that...

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George Cotzias
Jumat, 2026-07-31 07:04:45

He developed a method for measuring the amount of dopamine in brain tissues and found that dopamine levels in the basal ganglia, a brain area important...

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Kyotto
Sabtu, 2026-02-07 02:08:14

Jefferson and Shakin' Stevens among his influences. "Antimony/Sweet Escape", Dopamine White, 2020 "White Lights", Soundteller Records, 2020 CAVALIERE, PATRIZIO...

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Norepinephrine (medication)
Rabu, 2026-08-19 20:42:05

neurogenic shock, while showing fewer adverse side-effects compared to dopamine treatment. It stimulates α1 and α2 adrenergic receptors to cause blood...

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Major depressive disorder
Minggu, 2026-08-23 11:25:33

to dopamine receptor agonists, decreased dopamine receptor D1 binding in the striatum, and polymorphism of dopamine receptor genes implicate dopamine, another...

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CE-123
Minggu, 2025-12-21 12:51:08

"A heterocyclic compound CE-103 inhibits dopamine reuptake and modulates dopamine transporter and dopamine D1-D3 containing receptor complexes". Neuropharmacology...

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SKF-83,959
Kamis, 2026-05-28 05:48:04

derivative used in scientific research, acts as an agonist at the D1–D2 dopamine receptor heteromer. It behaves as a full agonist at the D1 protomer and...

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Caproxamine
Rabu, 2025-12-24 12:00:57

inhibitors Atomoxetine Reboxetine Viloxazine NDRIsTooltip Norepinephrine–dopamine reuptake inhibitors Amineptine‡ Bupropion Nomifensine‡ NaSSAsTooltip Noradrenergic...

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RG-7410
Kamis, 2026-06-04 09:30:54

amine-associated receptor 1 Agonists Endogenous Monoamine neurotransmitters Dopamine Histamine Epinephrine (adrenaline) Norepinephrine (noradrenaline) Serotonin...

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Serotonin antagonist and reuptake inhibitor
Sabtu, 2026-06-06 00:13:58

5-HT2A and inhibiting the reuptake of serotonin, norepinephrine, and/or dopamine. Additionally, most also antagonize α1-adrenergic receptors. The majority...

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6-Br-APB
Senin, 2026-02-16 10:17:35

6-Br-APB is a synthetic and selective dopamine D1 receptor agonist and stimulant-like drug of the 3-benzazepine family. It is a cyclized phenethylamine...

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4-Bromomethcathinone
Selasa, 2026-08-18 19:54:50

a serotonin-norepinephrine-dopamine releasing agent (SNDRA), and to a lesser degree, as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI)...

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PNU-120,596
Rabu, 2025-12-31 20:46:02

receptors. It is used in scientific research into cholinergic regulation of dopamine and glutamate release in the brain. Hurst RS, Hajós M, Raggenbass M, Wall...

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Phenylbutynamine
Minggu, 2025-12-21 16:06:32

related to β-phenethylamine and amphetamine. It acts as a norepinephrine–dopamine releasing agent (NDRA), albeit with far lower potency than β-phenethylamine...

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Roshan Cools
Kamis, 2026-03-26 14:13:06

was a brain scientist and she recalls conversations about the brain and dopamine at the dinner table. Cools studied neuropsychology at the University of...

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Xipranolol
Minggu, 2026-06-14 23:05:57

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Zolertine
Jumat, 2025-12-26 09:51:28

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Corticobasal degeneration
Kamis, 2026-07-30 12:08:20

ganglia which have difficulties receiving dopamine, typically asymmetrically. Specifically affected, are dopamine transporters which are presynaptic on the...

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Eugeroic
Minggu, 2026-06-14 14:16:04

Modafinil and armodafinil are thought to act as selective, weak, atypical dopamine reuptake inhibitors (DRIs). However, additional actions are also possible...

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ANKK1
Sabtu, 2025-10-11 05:41:01

in the coding region of the ANKK1 gene which controls the synthesis of dopamine in the brain. The A1 allele is associated with increased activity of striatal...

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Cocaine (data page)
Rabu, 2024-07-10 17:23:47

energy values. Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation, thorough-going elucidation...

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N-Methylheliamine
Kamis, 2026-07-02 02:33:15

Metirosine (α-methyl-p-tyrosine) Oudenone DBHTooltip Dopamine beta-hydroxylase Substrates→Products: Dopamine→Norepinephrine (Noradrenaline) Inhibitors: Bupicomide...

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Α-Methylphenylalanine
Kamis, 2026-08-20 17:23:30

Aromatic L-amino acid decarboxylase Substrates→Products: L-DOPA (levodopa)→Dopamine 5-HTP→Serotonin L-Histidine→Histamine Phenylalanine→Phenethylamine L-Tyrosine→Tyramine...

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Pamatolol
Rabu, 2025-12-31 20:54:28

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Pacrinolol
Jumat, 2026-08-21 21:33:56

(epinine, N-methyldopamine) Desglymidodrine Dexisometheptene Dipivefrine Dopamine Droxidopa (L-DOPS) DPIA Epinephrine Etilefrine Etilevodopa Ethylnorepinephrine...

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Eclanamine
Jumat, 2026-08-21 02:02:38

inhibitors Atomoxetine Reboxetine Viloxazine NDRIsTooltip Norepinephrine–dopamine reuptake inhibitors Amineptine‡ Bupropion Nomifensine‡ NaSSAsTooltip Noradrenergic...

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Cyr (album)
Minggu, 2026-06-14 01:21:24

later, the band released another single, which featured "Confessions of a Dopamine Addict" and "Wrath". This release also included 2 animated episodes of...

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SKF-89,145
Kamis, 2026-04-09 09:39:43

SKF-89,145 is a drug which acts as a dopamine agonist selective for the D1 subtype. The N-desmethyl derivative SKF-89,626 is also a selective D1 agonist...

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AGN-2979
Rabu, 2025-12-24 12:36:54

Aromatic L-amino acid decarboxylase Substrates→Products: L-DOPA (levodopa)→Dopamine 5-HTP→Serotonin L-Histidine→Histamine Phenylalanine→Phenethylamine L-Tyrosine→Tyramine...

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We Are Drugs
Rabu, 2026-06-10 06:15:16

band released their fifth album, Dopamine, in June 2015, Jenkins stated there were five to six songs from the Dopamine sessions that—once he had time to...

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