Sefazolin

Sefazolin
Data klinis
Nama dagangAncef, Cefazol, Kefzol
AHFS/Drugs.commonograph
Kategori
kehamilan
Rute
pemberian
Intravena, intramuskular
Kode ATC
Status hukum
Status hukum
  • Rx-saja
Data farmakokinetika
BioavailabilitasNA
Metabolisme?
Waktu paruh eliminasi1,8 jam (untuk IV)
2 jam (untuk IM)
EkskresiGinjal, tidak berubah
Pengenal
  • (6R,7R)-3-{[(5-metil-1,3,4-tiadiazol-2-yl)tio]metil}-8-okso-7-[(1H-tetrazol-1-ilasetil)amino]-5-tia-1-azabisiklo[4.2.0]okt-2-ena-asam-2-karboksilat
Nomor CAS
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.043.042 Sunting di Wikidata
Data sifat kimia dan fisik
RumusC14H14N8O4S3
Massa molar454.51 g/mol
Model 3D (JSmol)
  • O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)Cn3nnnc3)CSc4nnc(s4)C)C(=O)O
  • InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1 checkY
  • Key:MLYYVTUWGNIJIB-BXKDBHETSA-N checkY
  (verify)

Sefazolin (INN), juga dikenal sebagai cefazoline atau cephazolin, adalah antibiotik sefalosporin generasi pertama.

Obat ini biasanya diproses melalui penyuntikan intraotot (ke dalam otot besar) atau infus intrapembuluh (cairan intrapembuluh ke dalam pembuluh).

Merek

Cefazolin dipasarkan dengan nama-nama merek berikut: Cefacidal, Cefamezin, Cefrina, Elzogram, Faxilen, Gramaxin, Kefazol, Kefol, Kefzolan, Kezolin, Novaporin, Reflin, Zinol dan Zolicef.

Catatan kaki

Pranala luar

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