DOSEN PROFIL LENGKAP

peripheral stalks is dependent on the type of ATPase: F-ATPases have one, A-ATPases have two, and V-ATPases have three. The F1 catalytic domain is located...

expression patterns. This enzyme belongs to the family of P-type ATPases. The Na+/K+-ATPase helps maintain resting potential, affects transport, and regulates...

H+/K+ ATPase is a P2-type ATPase, a member of the eukaryotic class of P-type ATPases. Like the Ca2+ and the Na+/K+ ATPases, the H+/K+ ATPase functions...

are F-ATPases (which usually work as ATP synthases instead of ATPases in cellular environments) and running "in reverse" for an ATPase (ATPases catalyze...

active site of F-ATPase. Together with V-ATPases and A-ATPases, F-ATPases belong to superfamily of related rotary ATPases. F-ATPase consists of two domains:...

The P-type ATPases, also known as E1-E2 ATPases, are a large group of evolutionarily related ion and lipid pumps that are found in bacteria, archaea, and...

P-type ATPases undergo major conformational changes during the catalytic cycle. P-type ATPases are not evolutionary related to V- and F-type ATPases. P-type...

Vacuolar-type ATPase (V-ATPase) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms. V-ATPases acidify...

AAA (ATPases Associated with diverse cellular Activities) proteins (more commonly referred to as "triple-A ATPases") are a large group of protein family...

The ATPase assay is a membrane assay that indirectly measures the activity of efflux transporters. ATP Binding Cassette or efflux transporters mediate...

H+ -ATPases are specific for plants, fungi, and protists; and Na+ /K+ -ATPases are specific for animal cells. These two groups of P-type ATPases, although...

producing) catalytic core. The F-ATPases (or F1Fo ATPases), V-ATPases (or V1Vo ATPases) and A-ATPases (or A1Ao ATPases) are composed of two linked complexes:...

9, or proteolipid in F-ATPases, or the 16 kDa proteolipid in V-ATPases) was found in the Fo or Vo complex of F- and V-ATPases, respectively. The subunits...

Hydrogen ATPase commonly refers to: Hydrogen potassium ATPase, the gastric proton pump. Plasma membrane H+-ATPase V-ATPase, the synaptic vesicle transporter...

reticulum Ca2+ ATPase (SERCA) Secretory Pathway Ca2+ ATPase (SPCA) Calcium ATPases belong to a family of P-type primary ion transport ATPases that form an...

"AFG1, a new member of the SEC18-NSF, PAS1, CDC48-VCP, TBP family of ATPases". Yeast. 8 (9): 787–90. doi:10.1002/yea.320080912. PMID 1441755. T, Fujiki...

SPCA, or Secretory Pathway Ca2+-ATPase, is a calcium ATPase-type P-ATPase encoded for by the genes ATP2C1 and ATP2C2. SPCA is found primarily in the membranes...

Vanadate is a potent inhibitor of certain plasma membrane ATPases, such as Na+/K+-ATPase and Ca2+-ATPase (PMCA). Acting as a transition-state analog of phosphate...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

lineages include: RecA and rotor ATP synthase / ATPases (α and β subunits). Nucleic acid-dependent ATPases: helicases, Swi2, and PhoH (InterPro: IPR003714)...

ATPase GET3 (also known as ATPase ASNA1, arsenical pump-driving ATPase and arsenite-stimulated ATPase) is an enzyme that in humans is encoded by the gene...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

(January 1997). "Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases". The Journal of Experimental Biology. 200 (Pt 1): 1–8. Bibcode:1997JExpB...

cells. The presence of an ATPase was discovered in the membranes in 1961, and then in 1966 it was discovered that these ATPases pump Ca2+ out of the cytosol...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

their concentration gradient. Examples of ATPase pumps include P-type ATPase's, V-type ATPases, F-type ATPases, and ABC binding cassettes.[citation needed]...

as proton ATPases or H+ -ATPases) are proton pumps driven by the hydrolysis of adenosine triphosphate (ATP). Three classes of proton ATPases are found...

which can then be used as an energy source by the ATPases (CK is associated intimately with the ATPases, forming a functionally coupled microcompartment)...

concentration to ensure a strong binding between the motif and copper. As a P-type ATPases, ATP7B undergoes auto-phosphorylation of a key conserved aspartic acid...

S2CID 1477911. Forgac M (May 1999). "Structure and properties of the vacuolar (H+)-ATPases". The Journal of Biological Chemistry. 274 (19): 12951–4. doi:10.1074/jbc...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible...

calcium ATPase 2 (SERCA2) is an ATPase associated with Darier's disease and acrokeratosis verruciformis. This gene encodes one of the SERCA Ca(2+)-ATPases, which...

Wisconsin–Madison (B.S., 1983) Stanford University (Ph.D., 1988) Known for Clp/HSP1000 ATPases Scientific career Fields Biochemistry Institutions Massachusetts Institute...

proteasome complex. The gene PSMC6 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes...

12.3092. PMC 389597. PMID 5289252. Gibbons IR (November 1988). "Dynein ATPases as microtubule motors". The Journal of Biological Chemistry. 263 (31):...

the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport...

less specifically the S-isomer) of omeprazole. It works by blocking H+/K+-ATPase in the parietal cells of the stomach. It was patented in 1993 and approved...

1093/hmg/3.9.1647. PMID 7833924. Fagan MJ, Saier MH (January 1994). "P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic...

form a distinct group that is further apart from usual F-ATPases than A-ATPases are from V-ATPases. Human delta subunit of ATP synthase is coded by gene...

that decreases gastric acid secretion. It works by inactivating (H+/K+)-ATPase function in the stomach. The study of pantoprazole began in 1985, and it...

Southeast Asia in blowdart arrow poisons. It functions as a potent Na+/K+-ATPase inhibitor and has shown potential to induce apoptosis in chemotherapy-resistant...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

sequence motif - GYVG, glycine-tyrosine-valine-glycine - conserved in hslU ATPases and located on the inner surface of the assembled pore dramatically accelerates...

The ABC-type oligopeptide transporter (EC 7.4.2.6) or oligopeptide permease is an enzyme that catalyzes the chemical reaction ATP + H2O + oligopeptide(out)...

In molecular biology, ATP10 protein (mitochondrial ATPase complex subunit ATP10) is an ATP synthase assembly factor. It is essential for the assembly of...

Proton pump inhibitors (PPIs) block the gastric hydrogen potassium ATPase (H+/K+ ATPase) and inhibit gastric acid secretion. These drugs have emerged as...

S2CID 1477911. Forgac M (May 1999). "Structure and properties of the vacuolar (H+)-ATPases". The Journal of Biological Chemistry. 274 (19): 12951–12954. doi:10.1074/jbc...

is encoded by the ATP2A1 gene. This gene encodes one of the SERCA Ca2+-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic...

Myosin ATPase (EC 3.6.4.1) is an enzyme with systematic name ATP phosphohydrolase (actin-translocating). This enzyme catalyses the following chemical reaction:...

S2CID 1477911. Forgac M (May 1999). "Structure and properties of the vacuolar (H+)-ATPases". The Journal of Biological Chemistry. 274 (19): 12951–4. doi:10.1074/jbc...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

response to a touch stimulus, vanadate-sensitive K+, Mg2+ ATPase and Ca2+-translocating ATPases rapidly increase their activity. This increases transmembrane...

the family of P-type cation transport ATPases, and to the subfamily of aminophospholipid-transporting ATPases. The aminophospholipid translocases transport...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

the UCSC Genome Browser. Nishi T, Forgac M (2002). "The vacuolar (H+)-ATPases--nature's most versatile proton pumps". Nat. Rev. Mol. Cell Biol. 3 (2):...

inhibiting the Na/K-ATPase, also known as the sodium–potassium ion pump. However, adaptations to the alpha-subunit of the Na+/K+-ATPase via amino acid substitutions...

In enzymology, a Cl-transporting ATPase (EC 3.6.3.11) is an enzyme that catalyzes the chemical reaction ATP + H2O + Cl−out ⇌ {\displaystyle \rightleftharpoons...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

living things is a result of dephosphorylation of ATP by enzymes known as ATPases. The cleavage of a phosphate group from ATP results in the coupling of...

ATPase activity of a complex of transmembrane proteins that form the sodium potassium ATPase pump, (Na+/K+-ATPase). Inhibition of the Na+/K+-ATPase in...

PMC 9420854. PMID 36046184. Sarcoplasmic+Reticulum+Calcium-Transporting+ATPases at the U.S. National Library of Medicine Medical Subject Headings (MeSH)...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

decrease its rate of contractions by inhibiting the cellular sodium-potassium ATPase pump. Their beneficial medical uses include treatments for congestive heart...

are secreted via both H+-K+ATPases and H+ ATP-ases on the apical/luminal surface of the cell. By definition, the H+-K+ATPase reabsorbs one potassium ion...

Bibcode:1992AcCrC..48..551V. doi:10.1107/S0108270191010053. "P2A P-type ATPases: Ca2+-ATPases". IUPHAR/BPS Guide to PHARMACOLOGY. 2023. Laursen, Mette; et al...

In enzymology, a K+-transporting ATPase (EC 3.6.3.12) is an enzyme that catalyzes the chemical reaction ATP + H2O + K+out ⇌ ADP + phosphate + K+in The...

awarded to Danish chemist Jens Christian Skou for his discovery of the Na+/K+-ATPase. Boyer was born in Provo, Utah, and grew up in a nonpracticing Mormon family...

to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible...

In enzymology, a Fe3+-transporting ATPase (EC 7.2.2.7) is an enzyme that catalyzes the chemical reaction ATP + H2O + Fe3+out ⇌ {\displaystyle \rightleftharpoons...

proteasome complex. The gene PSMC2 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit...

proteasomal ATPases, which contains a specific motif (i.e., HbYX motif). The ATPases C-termini bind into pockets in the top of the 20S, and tether the ATPase complex...

enzymology, the complex is described as a mitochondrial protein-transporting ATPase (EC 7.4.2.3), or more systematically ATP phosphohydrolase (mitochondrial...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

original on March 6, 2010. Nishi T, Forgac M (2002). "The vacuolar (H+)-ATPases--nature's most versatile proton pumps". Nat. Rev. Mol. Cell Biol. 3 (2):...

2002). "Homologous and heterologous inhibitory effects of ATPase inhibitor proteins on F-ATPases". J. Biol. Chem. 277 (44): 41334–41. doi:10.1074/jbc.M207169200...

lysosomal lumen via a proton pump in the lysosomal membrane. Vacuolar-ATPases are responsible for the transport of protons, while the counter transport...

dodecamer with RUVBL2 protein. Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity; hexamerization is thought...

disease are both caused by mutations in copper ATPases that are distinct for each disease. Both ATPases, ATP7A (Menkes) and ATP7B (Wilson's) are located...

transmembrane pump that exports calcium from the cell is the plasma membrane Ca2+ ATPase (PMCA), which has a much higher affinity but a much lower capacity. Since...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

to the plasma membrane Ca2+ ATPase (PMCA) and turns it into an ion channel, similar to how palytoxin turns the Na+/K+-ATPase into a sodium channel. Ultimately...

ATPase family AAA domain-containing protein 3B (or ATAD3B) is a protein that in humans is encoded by the ATAD3B gene. ATAD3 is part of the AAA protein...

an ion-transporting enzyme, Na+, K+ -ATPase." Adenosine-tetraphosphatase Adenosine methylene triphosphate ATPases ATP test Creatine Cyclic adenosine monophosphate...

luminal sodium channels. Aldosterone also increases the number of Na⁺/K⁺-ATPase pumps that allow increased sodium reabsorption and potassium excretion....

5×10−3 0.10 0.041 Yes (e.g. Na+/K+-ATPase) Hypernatremia 1 17 Chlorine 1.5×10−3 0.095 0.027 Yes (e.g. Cl-transporting ATPase) Hyperchloremia 17 12 Magnesium...

of low-copy-number plasmids, it consists of three components: the ParA ATPase, the ParB DNA-binding protein, and the cis-acting parS sequence. The parA...

proteasome complex. The gene PSMC3 encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit...

of dynein heavy chain based on homology to the AAA family of oligomeric ATPases". Structure. 9 (2). London, England: 93–103. doi:10.1016/S0969-2126(00)00557-8...

instance, ATPase fiber type is related to contraction speed, because high ATPase activity allows faster crossbridge cycling. While ATPase activity is...

the Na,K-ATPase. Each of these auxiliary subunits produces a distinct functional effect on the transport characteristics of the Na,K-ATPase that is adjusted...

on among other things the content of myoglobin, mitochondria, and myosin ATPase, etc.[citation needed] The word muscle comes from Latin musculus, diminutive...

DNA-dependent ATPase, abbreviated Dda and also known as Dda helicase and Dda DNA helicase, is the 439-amino acid 49897 dalton protein coded by the Dda...

to drive ATP synthesis. These ATPases can also work in reverse to hydrolyse ATP to create a proton gradient. The ATPase F1 complex gamma subunit forms...

Na+/K+-ATPase. However, in experiments with patients where the Na+/K+-ATPase had been blocked in the underarm by infusion of the Na+/K+-ATPase-blocker...

protein myosin. The term has been extended to include a group of similar ATPases found in the cells of both striated muscle tissue and smooth muscle tissue...

S2CID 1477911. Forgac M (1999). "Structure and properties of the vacuolar (H+)-ATPases". Journal of Biological Chemistry. 274 (19): 12951–12954. doi:10.1074/jbc...

with certain mutant proteins or complexes. Mutations in genes affecting V-ATPase synthesis and assembly, vesicle transport machinery, and protein sorting...

The INO80 subfamily of chromatin remodeling complexes are ATPases, and includes the INO80 and SWR1 complexes. One of the main roles of the INO80 subfamily...

plasma membrane vesicles and partial characterisation of the plasma membrane ATPase". Malaria Journal. 1 6. doi:10.1186/1475-2875-1-6. ISSN 1475-2875. PMC 111504...

while simultaneously expending energy to excrete salt through the Na+/K+-ATPase ionocytes (formerly known as mitochondrion-rich cells and chloride cells)...

Christian Skou (Chemistry, 1997) conducted his groundbreaking work on the Na/K-ATPase in Aarhus and remained employed at the university until his retirement....

is a member of the AAA+ (extended family of ATPases associated with various cellular activities) ATPase family. Enzymes of this family are found in all...

encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during...

lobes separated by a deep cleft. The bottom of the cleft represents the "ATPase fold", a structure conserved among ATP and GTP-binding proteins that binds...

system, a type VII bacterial secretion system, includes Rv3877 and two AAA ATPases, Rv3870 and Rv3871, the latter a cytosolic protein, as subunits. The ESAT-6/CFP-10...

that in humans is encoded by the SLN gene. Sarcoplasmic reticulum Ca2+-ATPases are transmembrane proteins that catalyze the ATP-dependent transport of...

vacuolar (H+)-ATPases". J. Biol. Chem. 274 (19): 12951–4. doi:10.1074/jbc.274.19.12951. PMID 10224039. Kane PM (1999). "Introduction: V-ATPases 1992-1998"...

In enzymology, a heme-transporting ATPase (EC 3.6.3.41) is an enzyme that catalyzes the chemical reaction ATP + H2O + hemein ⇌ {\displaystyle \rightleftharpoons...

Reptin is a tumor repressor protein that is a member of the ATPases Associated with various cellular Activities (AAA+) helicase family and regulates KAI1...

Cardenolides are toxic to animals through inhibition of the enzyme Na+/K+-ATPase, which is responsible for maintaining the sodium and potassium ion gradients...

Obg-like ATPase 1 is an enzyme that in humans is encoded by the OLA1 gene. Ola1 belongs to the protein family of Obg-like GTPases but defines an exceptional...

skin-cell genes until they were able to identify ATP2B1, a calcium transporting ATPase, as a host factor supporting cytotoxicity. The research showed the therapeutic...

proton ATPase (V-ATPase) 116 kDa subunit a isoform 3 enzyme. TCIRG1 (T cell immune regulator 1) is a gene that encodes the V-type proton ATPase (V-ATPase) 116...

diacetyl and biacetyl). Its biological effects include inhibiting certain ATPases. The compound can be prepared from butanone by reaction with ethyl nitrite...

RHA, RNA helicase A, RNA helicase DDX3, RNA helicase Hera, RNA-dependent ATPase, TGBp1 NTPase/helicase domain, VRH1, GRTH/DDX25). Jankowsky, Eckhard. RNA...

molecules to pass through the cell membrane. Active transport of protons by H+ ATPases alters membrane potential allowing for facilitated passive transport of...

Folliculin-interacting protein 1 (FNIP1) functions as a co-chaperone which inhibits the ATPase activity of the chaperone Hsp90 (heat shock protein-90) and decelerates...

encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during...

P-type ATPases". J. Biol. Chem. 273 (49): 32614–7. doi:10.1074/jbc.273.49.32614. PMID 9830000. Krijger GC, Williams LE (2005). "The plant P1B-type ATPase AtHMA4...

Flores-Maldonado, Catalina; Shoshani, Liora; Ponce, Arturo (2024-06-01). "Na+/K+-ATPase: More than an Electrogenic Pump". International Journal of Molecular Sciences...

haustorium contains amino acid- and hexose sugar- transporters and H+-ATPases which are used for active transport of nutrients from the plant, nourishing...

In enzymology, a nucleoplasmin ATPase (EC 3.6.4.11) is an enzyme that catalyzes the chemical reaction ATP + H2O ⇌ {\displaystyle \rightleftharpoons } ADP...

ATPases work to strip the factors from the maturing 60S pre-ribosome. One of the ATPases is a dynein-like Rea1 protein made up of 6 different ATPase domains...

doctoral research at the University of Pennsylvania involved studies of the ATPase pathway of axonemal dynein. She worked as a postdoctoral researcher at Pennsylvania...

In enzymology, a Mg2+-importing ATPase (EC 3.6.3.2) is an enzyme that catalyzes the chemical reaction ATP + H2O + Mg2+out ⇌ {\displaystyle \rightleftharpoons...

where the hydrolysis of ATP to ADP and an inorganic phosphate at the P-type ATPase moves three sodium ions back out of the cell and two potassium ions into...

G1 to S phase cell cycle transition. Another function of Hsc70 is as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane...

belongs to the family of P-type cation transport ATPases and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible...

; Shiryaeva, Tatiana N.; Strongin, Alex Y. (2009). "NS4A regulates the ATPase activity of the NS3 helicase: a novel cofactor role of the non-structural...

convoluted tubule, activating epithelial sodium channels (ENaC) and the Na⁺/K⁺-ATPase pump. This results in the absorption of sodium (with resulting retention...

noting "an ATPase most similar to the mimivirus homologue" and a major capsid protein phylogeny that is "not compatible with that of the ATPase phylogeny"...

cellular pH homeostasis. There are three classes of ATPases- F, P, and V. The vacuolar (V-type) ATPases have a transmembrane proton-conducting sector and...

In enzymology, a guanine-transporting ATPase (EC 3.6.3.37) is an enzyme that catalyzes the chemical reaction ATP + H2O + guanineout ⇌ {\displaystyle \rightleftharpoons...

retinitis pigmentosa (NARP) syndrome mtDNA mutation (T8993G) triggers muscle ATPase deficiency and hypocitrullinaemia". European Journal of Pediatrics. 158...

to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible...

acid substitutions at well-defined positions of the α-subunit of Na+,K+-ATPase (ATPalpha). Variation in ATPalpha has been surveyed in various CTS-adapted...

Wilson's disease involves a mutation of the gene coding for the enzyme ATPase 7B, which prevents copper within the liver from entering the Golgi apparatus...

lumen of the stomach. The pH level is maintained by the proton pump H+/K+ ATPase. The parietal cell releases bicarbonate into the bloodstream in the process...

the inner membrane. GspE belongs to the type II/type IV secretion ATPase family. ATPases belonging to this family have a distinct hexameric structure. Each...

Chaperonin ATPase (EC 3.6.4.9, chaperonin) is an enzyme with systematic name ATP phosphohydrolase (polypeptide-unfolding). This enzyme catalyses the following...

Ghosh M, Rosen BP (October 1999). "Families of soft-metal-ion-transporting ATPases". Journal of Bacteriology. 181 (19): 5891–7. doi:10.1128/JB.181.19.5891-5897...

The base consists of a ring of six AAA ATPases (Subunit Rpt1-6, systematic nomenclature) and four non-ATPase subunits (Rpn1, Rpn2, Rpn10, and Rpn13)...

In enzymology, an arsenite-transporting ATPase (EC 3.6.3.16) is an enzyme that catalyzes the chemical reaction ATP + H2O + arsenitein ⇌ {\displaystyle...

mammalian mitochondrial DNA: coding portions of genes for 2 subunits of ATPase overlap. DNA encodes protein sequence by a series of three-nucleotide codons...

metal binding. The fourth HMA domain of the Menke's copper transporting ATPase shows a well-defined structure comprising a four-stranded antiparallel beta-sheet...

reference expression data Gene ontology Molecular function DNA binding ATPase binding transcription coactivator activity p53 binding C2H2 zinc finger...

another protein embedded in their membrane: vacuolar-type H+-ATPase or V-ATPase. This ATPase pumps H+ ions into the vesicle lumen, lowering its pH with...

juvenile bull sharks (Carcharhinus leucas): plasma osmolytes and Na+/K+-ATPase activity in gill, rectal gland, kidney and intestine" (PDF). Journal of...

tungsten-binding protein of ABC family of transporters WtpB is a permease WtpC is ATPase Mod and Tup systems, which belong to the ABC family, have also been identified...

encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during...

the P-type cation transport ATPase family and specifically belongs to the subfamily of aminophospholipid-transporting ATPases. This protein is highly expressed...

member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have...

proteasome complex. The gene PSMC1 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. The human...

TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase, mitochondrial Ca2+ uniporter, tubulin, myosin light-chain phosphatase,...

interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties". Proceedings of the...

AFG3 ATPase family gene 3-like 2 (S. cerevisiae) is a protein that in humans is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria...

the other aminocoumarin antibiotics act as competitive inhibitors of the ATPase reaction catalysed by GyrB. The potency of novobiocin is considerably higher...

"The Story of RNA Unfolded: The Molecular Function of DEAD- and DExH-Box ATPases and Their Complex Relationship with Membraneless Organelles". Annual Review...

turning ADP into ATP. Indeed, in the closely related vacuolar type H+-ATPases, the hydrolysis reaction is used to acidify cellular compartments, by pumping...

In enzymology, a proteasome ATPase (EC 3.6.4.8) is an enzyme that catalyzes the chemical reaction ATP + H2O ⇌ {\displaystyle \rightleftharpoons } ADP +...

somnolence via another mechanism. Insulin increases the activity of Na/K ATPase, causing increased movement of potassium into cells from the extracellular...

affect the flow of calcium ions, and they affect the function of the Na+/K+ ATPase, and are necessary for maintaining potassium levels. Low blood magnesium...

NE (June 2015). "Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early...

aldosterone increases activity of basolateral membrane sodium-potassium ATPase and apical epithelial sodium channels, ENaC, as well as potassium channels...

proteasome complex. The gene PSMC5 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition...

Bowman EJ, Bowman BJ, et al. (September 1989). "Evolution of the vacuolar H+-ATPase: implications for the origin of eukaryotes". Proceedings of the National...

active transport into the stomach. The gastric hydrogen potassium ATPase (H+/K+ ATPase) is highly enriched in parietal cells and transports H+ against a...

belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible...

factor C (RFC), which is a heteropentameric member of the AAA+ class of ATPases. Expression of PCNA is under the control of E2F transcription factor-containing...

drives the maturation of endosomes by transporting vacuolar (H+)-ATPases (V-ATPases) from trans-Golgi network to endocytic vesicles. RAB5A has been shown...

In enzymology, a lipopolysaccharide-transporting ATPase (EC 3.6.3.39) is an enzyme that catalyzes the chemical reaction ATP + H2O + lipopolysaccharidein...

Tsivkovskii R, Tsivkovskaia N, Lutsenko S (2005). "The copper-transporting ATPases, Menkes and Wilson disease proteins, have distinct roles in adult and developing...

α-Aminoadipate pathway, for the synthesis of the amino acid L-lysine AAA proteins (ATPases Associated with various cellular Activities) Abdominal aortic aneurysm...

In enzymology, a vitamin B12-transporting ATPase (EC 3.6.3.33) is an enzyme that catalyzes the chemical reaction ATP + H2O + vitamin B12out ⇌ {\displaystyle...

SMC proteins represent a large family of ATPases that participate in many aspects of higher-order chromosome organization and dynamics. SMC proteins are...

nucleosome sliding in order to regulate gene transcription. It contains an ISWI ATPase, making it part of the ISWI family of chromatin remodeling complexes. NURF...

water; but is permeable to ions allowing for some sodium reabsorption. Na/K-ATPase is expressed at very low levels in this segment and thus this reabsorption...

In enzymology, a xenobiotic-transporting ATPase (EC 3.6.3.44) is an enzyme that catalyzes the chemical reaction ATP + H2O + xenobioticin ⇌ {\displaystyle...

Initialism for North Korean Army, also known as the Korean People's Army Na+/K+-ATPase, an enzyme located in the plasma membrane in all animals Karate Canada,...

classified into 4 classes. Tubulin-like, actin-like, Walker A cytoskeletal ATPases (WACA-proteins), and intermediate filaments. Tubulin-like proteins are...

CD95 death-inducing signaling complex nuclear envelope VCP-NPL4-UFD1 AAA ATPase complex perinuclear region of cytoplasm nucleus Biological process positive...

is composed of only the hydrogenase, the respiratory chain, and the F1F0-ATPase, which remain separate from the anabolic subsystems. C. metallidurans can...

contain a number of protein pumps and antiporters, including aquaporins, ATPases and Ca2+/H+ and Na+/H+ antiporters. They may be the only cellular organelle...

encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during...

In enzymology, a peptide-transporting ATPase (EC 3.6.3.43) is an enzyme that catalyzes the chemical reaction ATP + H2O + peptidein ⇌ {\displaystyle \rightleftharpoons...

members of the realm also encode genome packaging ATPases of the FtsK-HerA superfamily. The ATPases in Varidnaviria are enzymes that package the viral...

on its own but oligomerizes into tetradecamers when bound to ATPases. It needs an ATPase to identify, unfold, and transfer targeted big proteins into...

sodium translocating F-type and V-type ATPases P-type calcium ATPase (five different conformations) Calcium ATPase regulators phospholamban and sarcolipin...

realm of bacterial viruses (bacteriophages) that encode an FtsK family ATPase and hydrophobic major capsid proteins (MCPs) that are forced out from the...

encoding the Neurospora vacuolar ATPase. Analysis of vma-1 encoding the 67-kDa subunit reveals homology to other ATPases". J Biol Chem. 263 (28): 13994–4001...

Sodium/potassium transporting ATPase interacting 1 is a protein that in humans is encoded by the NKAIN1 gene. NKAIN1 is a member of a family of mammalian...

(1999). "Mutagenesis of two conserved tryptophan residues of the E-type ATPases: inactivation and conversion of an ecto-apyrase to an ecto-NTPase". Biochemistry...

Coumermycin A1 is an aminocoumarin. Its main target is the ATPase site of the DNA gyrase GyrB subunit. It was developed in the early 1960's by Bristol...

expression data Gene ontology Molecular function nucleotide binding GDP binding ATPase binding GTP binding protein binding GTPase activity ubiquitin protein ligase...

encodes the p80 subunit. This protein is a member of the AAA family of ATPases. GRCh38: Ensembl release 89: ENSG00000186625 – Ensembl, May 2017 GRCm38:...

In enzymology, a phospholipid-translocating ATPase (EC 3.6.3.1) is an enzyme that catalyzes the chemical reaction ATP + H2O + phospholipid in ⇌ {\displaystyle...

"Human liver cDNA clones encoding proteolipid subunit 9 of the mitochondrial ATPase complex". Biochemical and Biophysical Research Communications. 144 (3):...

G, Ferreira-Cerca S, De Wulf P (April 2019). "The Rio1 protein kinases/ATPases: conserved regulators of growth, division, and genomic stability". Current...

enzymes that perform this type of transport are transmembrane ATPases. A primary ATPase universal to all animal life is the sodium-potassium pump, which...

generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous...

transcription factor for MAX. DDX39B DExD-Box Helicase 39B RNA-dependent ATPase that mediates ATP hydrolysis during mRNA splicing. C17orf85 Nuclear Cap-Binding...

sequence-specific DNA binding DNA-binding transcription factor activity ATPase binding zinc ion binding DNA-binding transcription activator activity, RNA...

the pump gene ATP1A3, among other genes that are not ion transporters. ATPase (ion pumps) Kim JB (January 2014). "Channelopathies". Korean Journal of...

subunit of the bacterial Sec export pathway and of a protein-secreting ATPase complex, also known as a SecYEG translocon. Homologs of the SecYEG complex...

flippases and floppases are powered by ATP hydrolysis and are either P4-ATPases or ATP-Binding Cassette transporters. Scramblases are energy-independent...

1016/S0163-4453(05)80037-4. PMID 1602151. Ohta S, Kagawa Y (1986). "Human F1-ATPase: molecular cloning of cDNA for the beta subunit". J. Biochem. 99 (1): 135–41...

membrane-bounded organelle membrane Golgi membrane Golgi apparatus VCP-NPL4-UFD1 AAA ATPase complex Biological process adaptive immune response positive regulation...

substrate; a central domain (similar to ATP-binding domains of several ATPases and GTPases); and a C-terminal domain (similar to dihydrofolate reductase...

hydrolysis. Biology portal Phosphorylase Serine hydrolase Cadmium-transporting ATPase "Hydrolase - Chemistry Encyclopedia - water, examples, molecule". www.chemistryexplained...

kidney, and placenta. The gene codes for a P-type (cation transport enzyme) ATPase that transports copper into bile and incorporates it into ceruloplasmin...

many leaderless mRNAs probably initiated by scanning. The process of ABCE1 ATPase-based recycling is also shared with eukaryotes. Being a prokaryote without...

reference expression data Gene ontology Molecular function nucleotide binding ATPase activity ATP binding protein binding microtubule motor activity microtubule...

electrochemical gradient is the activity of the sodium-potassium pump (Na/K ATPase), which utilizes active transport to pump two potassium (K+) ions into the...

on itself, bringing the N- and C-termini together to form a globular ABC ATPase head domain. Rad50 can dimerize both through its head domain and through...

Gene ontology Molecular function nucleotide binding microtubule binding ATPase activity ATP binding microtubule motor activity minus-end-directed microtubule...

oxidoreductase activities while another formed a structurally and sequentially novel ATPase. Another group generated a family of G-protein coupled receptors that could...

role relates to DNA repair. sbcC genes encode protein that function as ATPases. The upstream location of sbcC motif RNAs could suggest a function as cis-regulatory...

homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CK-BB forms...

interior and the exterior of the cell for depolarization. This pump is an ATPase that pumps three sodium ions out of the cell and two potassium ions into...

DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins. More information about this protein can...

while simultaneously expending energy to excrete salt through the Na+/K+-ATPase ionocytes (formerly known as mitochondrion-rich cells and chloride cells)...

N-terminal residues (Helicase and, RecQ-Ct domains) impairs both helicase and ATPase activity but has no effect on the binding ability of RecQ implying that...

reuptake energetically favorable. The gradient is generated by the Na+/K+-ATPase which transports three sodium ions out and two potassium ions into the cell...

comprehensive 2003 study analyzing mtDNA sequences of Cytochrome b and ATPase subunit 8 suggests that 12 living species of owlet-nightjar should be recognized...

creatures, V-ATPase is a necessary component for life but Nelson discovered that yeast can overcome the constraints of non-function V-ATPase when living...

transport of calcium out of the cell. In addition, the plasma membrane Ca2+ ATPase (PMCA) obtains energy to pump calcium out of the cell by hydrolysing adenosine...

In enzymology, a taurine-transporting ATPase (EC 3.6.3.36) is an enzyme that catalyzes the chemical reaction. ATP + H2O + taurineout ⇌ {\displaystyle \rightleftharpoons...

Several other homologues such as those of a helicase-primase, a packaging ATPase, an insertion sequence transposase DNA-binding subunit, and a Zn-ribbon...

protein, a member of the AAA+ ATPase protein family (ATPases associated with diverse cellular activities). Many AAA+ ATPases, including DnaA, form oligomers...

proton motive force is generated and used to drive ATP production via an ATPase. Most photosynthetic microbes are autotrophic, fixing carbon dioxide via...

tubule of a nephron and stimulation of aldosterone that activates Na+/K+-ATPase at collecting duct. Inhibition of sodium-chloride symporter increases availability...

In enzymology, a vesicle-fusing ATPase (EC 3.6.4.6) is an enzyme that catalyzes the chemical reaction ATP + H2O ⇌ {\displaystyle \rightleftharpoons } ADP...

tension. Also, all three of these proteins may have a role in inhibiting the ATPase activity of the myosin complex that otherwise provides energy to fuel muscle...

FtsH-homology protease domain as well as an AAA+ homology ATPase domain. The protein is thought to use ATPase-driven conformational changes to the AAA-domain in...

remains one of the most abundant proteins in all of Eukarya and is an enzyme (ATPase) that gradually hydrolyzes ATP. It exists in two forms within eukaryotic...

these involve the hydrolysis of ATP and had been previously classified as ATPases (EC 3.6.3.-), although the hydrolytic reaction is not their primary function...

proteins, DNA-binding proteins from plants and hBRG1 protein, a central ATPase of the human switching/sucrose non-fermenting (SWI/SNF) remodeling complex...

Steroid-transporting ATPase, an enzyme Xenobiotic-transporting ATPase, an enzyme Myosin ATPase, an enzyme Dynein ATPase, an enzyme Chaperonin ATPase, an enzyme...

reason for the high sensitivity of fish is the effect of bifenthrin as ATPase-inhibitor. The gills need ATP to control the osmotic balance of oxygen....

powered by the hydrolysis of adenosine triphosphate (ATP) (thus kinesins are ATPases, a type of enzyme). The active movement of kinesins supports several cellular...

2004). "Paying the Price at the Pump: Dystonia from Mutations in a Na+/K+-ATPase". Neuron. 43 (2): 153–154. doi:10.1016/j.neuron.2004.07.002. PMID 15260948...

proteins and one or two of which are membrane-associated AAA ATPases.[citation needed] The ATPase subunits utilize the energy of adenosine triphosphate (ATP)...

abundance and/or activity of a variety of ion channel, carriers, and the Na+/K+-ATPase. Over the past few years, there has been increasing evidence that SGK1 expression...

BAG2 gene. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately...

Matsumoto, Mitsuharu; Ohishi, Hifumi; Benno, Yoshimi (2004-05-15). "H+-ATPase activity in Bifidobacterium with special reference to acid tolerance". International...

synchronizes an array of biological processes, (such as Ca2+, Na+, K+ -ATPase) thus maintaining membrane potential and controlling intracellular pH and...

complete inventory of the yeast Saccharomyces cerevisiae P-type transport ATPases" (PDF). FEBS Lett. 409 (3): 325–32. Bibcode:1997FEBSL.409..325C. doi:10...

that contains the genes for cytochrome c oxidase subunits II and III and ATPase subunit 6". Nucleic Acids Research. 11 (12): 4211–27. doi:10.1093/nar/11...

iron-sulfur protein and Qcr10 into pre-Complex III is then driven by the AAA-ATPase BCS1L, completing the assembly of complex III. FMC1 acts as an assembly...

by this gene, FANCM displays DNA binding against fork structures and an ATPase activity associated with DNA branch migration. It is believed that FANCM...

radiation striking a surface which is reflected off it.), and increased Na+/K+-ATPase in the gills. A number of mechanisms assist with osmoregulation. Nichols...

foxglove (Digitalis purpurea), which is now known to act as a sodium-potassium ATPase inhibitor, increasing stroke volume and decreasing heart rate; at the time...

across many ATPases and helicases. The proline at position 47 (P47) and the methionine at position 299 (M299) are both important for ATPase activity, with...

phospholamban to induce superinhibition of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs)". The Journal of Biological Chemistry. 277 (30): 26725–8. doi:10...

AHSA2 also known as AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) is a human gene which encodes a protein which acts as co-chaperone...

In enzymology, a molybdate-transporting ATPase (EC 3.6.3.29) is an enzyme that catalyzes the chemical reaction ATP + H2O + molybdateout ⇌ {\displaystyle...

transmembrane Ca2+ binding sites. Classical theory of active transport for P-type ATPases Data from crystallography studies by Chikashi Toyoshima applied to the...

[citation needed] An example of active transport of ions is the Na+-K+-ATPase (NKA). NKA is powered by the hydrolysis of ATP into ADP and an inorganic...

rivastigmine plus selegiline on brain acetylcholinesterase, (Na, K)-, Mg-ATPase activities, antioxidant status, and learning performance of aged rats"....

lysosome-associated complex with Ragulator and vacuolar adenosine triphosphatase (v-ATPase) interact with mTORC1 in response to amino acids from the lysosomal lumen...

W; Hoque, AE; Mungrue, IN; Husain, M (2003). "Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness...

fragment holds a critical funtion, as it is responsible for regulation ATPase enzymatic activity and mediating the binding interaction with actin filaments...

urticae. Ethanol extract inhibit the gastric enzyme hydrogen potassium ATPase that produces stomach acid. Saponaria officinalis contains several saponins...

by a kleisin subunit, forming a closed ring. These two SMC proteins have ATPase domains at their heads, which bind together and hydrolyze ATP. Cycles of...

endosomes, studies used Bafilomycin A1, which is known to block the v-type H+-ATPases of endosomes. This reduces the acidity in endosomes. The physiological...

Masarik M, Adam V, Provaznik I, Kizek R (September 2013). "From Na+/K+-ATPase and cardiac glycosides to cytotoxicity and cancer treatment". Anti-Cancer...

protein that in humans is encoded by the MDN1 gene. Midasin is a member AAA ATPase family. ENSG00000288121 GRCh38: Ensembl release 89: ENSG00000112159, ENSG00000288121...

activity per gram of gill tissue is lower for deep-sea fishes, the Na+/K+ -ATPases of deep-sea fishes exhibit a much higher tolerance of hydrostatic pressure...

which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L". Journal of Cell Science. 121 (Pt 15): 2588–600. doi:10.1242/jcs...

been shown that retinoschisin interacts with the sodium/potassium-ATPase (Na/K-ATPase) which resides in the plasma membrane. RS1 also plays a role in the...

ontology Molecular function microtubule motor activity nucleotide binding ATPase activity cytoskeletal motor activity ATP binding minus-end-directed microtubule...

skeletal muscle. These micropeptides interact with sarcoplasmic reticulum Ca2+-ATPase (SERCA), a membrane pump responsible for regulating Ca2+ uptake into the...

DNA segregates in a poorly-understood mechanism (likely via ParA-like ATPases). A ring is assembled at the future division site: In archaea that use...

In enzymology, a Cd2+-exporting ATPase (EC 3.6.3.3) is an enzyme that catalyzes the chemical reaction ATP + H2O + Cd2+in ⇌ {\displaystyle \rightleftharpoons...

cortical collecting tubule and active secretion of protons via proton ATPases in the lumenal membrane of the intercalated cells of the collecting tubule...

low-energy state is failure to maintain axonal transport via dynein/kinesin ATPases, which in many diseases results in neuronal injury to both the brain and/or...

twitch muscles. Although slower, the sarco/endoplasmic reticulum calcium-ATPase (SERCA) actively pumps Ca2+ back into the sarcoplasmic reticulum, resulting...

(Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma)...

increased deposition of sodium and chloride in endothelial cells and Na+K+ATPase activity plays a role in expelling Na followed by chloride and water from...

the basolateral membrane. Increases in sodium opens the sodium-potassium ATPase channels, removing the excess sodium back out across the basolateral membrane...

measurement system Fuel oil, also called Furnace Oil FO, a subunit of F1FO type ATPase enzyme Field officer, a senior army officer First Officer, or co-pilot on...

Probable phospholipid-transporting ATPase IF is an enzyme encoded by the ATP11B gene in humans. P-type ATPases, such as ATP11B, are phosphorylated in...

heterodimeric protein first discovered in sea urchins. It contains a 60 kDa ATPase subunit, encoded by KATNA1, which functions to sever microtubules. This...

Dixon R (June 1992). "The prokaryotic enhancer binding protein NTRC has an ATPase activity which is phosphorylation and DNA dependent". The EMBO Journal....

can steer regeneration. In Xenopus tadpoles, activating a proton pump (V-ATPase) that moves hydrogen ions out of cells is necessary for tail regrowth and...

they focus on are H+-ATPases, Ca2+-ATPases, and Na+/H+ exchangers. The Rao Lab defined the secretory pathway Ca2+, Mn2+-ATPases (SPCA) and later discovered...

(together with Paul D. Boyer and John E. Walker) for his discovery of Na+,K+-ATPase, the first at Aarhus University. Skou had taken a few years away from his...

triphosphate, an organic chemical used for driving biological processes ATPase, any enzyme that makes use of adenosine triphosphate Advanced Technology...

domain can be found from amino acid 743–1333, and is domain associated with ATPase involved in DNA repair. There is also a domain of unknown function from...

transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix...

sodium-potassium pumps in cardiac muscle cells via inhibition of Na+/K+-ATPase. In addition to its cardiac effects, symptoms of poisoning include numbness...

The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the...

proteasome complex. The gene PSMC4 encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit...

other cardenolide-resistant insects rely on a resistant form of the Na+/ K+-ATPase enzyme to tolerate significantly higher concentrations of cardenolides than...

activation suppresses the activity of sodium–hydrogen antiporter and Na+/K+-ATPase, preventing reabsorption of sodium. D5 receptors are thought to positively...

Pertille A, Santo Neto H (May 2009). "Sarcoplasmic-endoplasmic-reticulum Ca2+-ATPase and calsequestrin are overexpressed in spared intrinsic laryngeal muscles...

inheritance. Some examples are spastin (SPG4) and paraplegin (SPG7) are both AAA ATPases. The genes are designated SPG (Spastic gait gene). The gene locations are...

possess an F-type ATPase (unusual for archaea, but common for bacteria, mitochondria and chloroplasts) along with an A-type ATPase. M. acetivorans has...

some degree of merit. The resolution provided by the mtDNA 12S rRNA and ATPase subunits six and eight sequence data is not sufficient to resolve several...

secretion of proteins through the cell membrane. Within this system the SecA ATPase forms a translocase complex with the SecYEG channel, thereby driving the...

convoluted tubule possess the ATP-powered sodium-potassium antiporter (Na+/K+-ATPase), which uses energy from ATP to transfer three sodium ions out from the...

function microtubule binding microtubule motor activity nucleotide binding ATPase activity protein binding ATP binding Cellular component cytoplasm male germ...

pepsinogen and gastric lipase, expressed in gastric chief cells; and a gastric ATPase and gastric intrinsic factor, expressed in parietal cells. In the early...

Vacuolar ATPase (vATPase) maintains the acidic pH in lysosomes and it has been shown that TMEM106B interacts with accessory proteins of vATPase. When TMEM106B...

Denmark "for the first discovery of an ion-transporting enzyme, Na+, K+ -ATPase" 2000 Physiology Arvid Carlsson 1923–2018 Sweden "for their discoveries...

lead is able to cause harm is its ability to be transported by calcium ATPase pumps across the BBB, allowing for direct contact with the fragile cells...

phosphorylation. F-type ATPases (Adenylpyrophosphatase ) typically use protons as the sole coupling ion, but the F1F0 ATPase of Propionigenium modestum...

In enzymology, a polyamine-transporting ATPase (EC 3.6.3.31) is an enzyme that catalyzes the chemical reaction ATP + H2O + polyamineout ⇌ {\displaystyle...

transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1". J. Biol. Chem. 280 (13): 12799–809. doi:10.1074/jbc.M413968200. PMID 15632132...

autophagy. BAG proteins compete with Hip-1 for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately...

glycosides is positive inotropy. Glycosides bind to the sarcolemma transmembrane ATPase of cardiac muscle cells and compete with K+ ions, inactivating the enzyme...

It was here that Racker demonstrated that glycolysis was dependent on ATPase and the continuous regeneration of ADP and phosphate. Maynard E. Pullam...

ecosystem by SM Brand Marketing Cervélo P2C, a Cervélo bike P2C ATPases, a group of P-type ATPase transport proteins This disambiguation page lists articles...

26S proteasome non-ATPase regulatory subunit 5 is an enzyme that in humans is encoded by the PSMD5 gene. The 26S proteasome is a multicatalytic proteinase...

translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional...

share the existence of an ATPase motor which facilitates chromatin sliding on DNA through the binding and hydrolysis of ATP. ATPase has an open and closed...

vasopressin and nitric oxide into CSF. A Na-K-Cl cotransporter and Na/K ATPase found on the surface of the choroid endothelium, appears to play a role...

ATP across the inner membrane during oxidative phosphorylation. F-type ATPases consist of two structural domains, F1 and F0, that contribute to catalysis...

pepsinogen PGC and the lipase LIPF, expressed in chief cells, and gastric ATPase ATP4A and gastric intrinsic factor GIF, expressed in parietal cells of the...

transporter EC 7.2.2.19: H+/K+-exchanging ATPase EC 7.2.2.20: ABC-type Zn2+ transporter EC 7.2.2.21: Cd2+-exporting ATPase EC 7.2.2.22: P-type Mn2+ transporter...

caused by a variety of mutations in ATP8B1, a gene coding for a P-type ATPase protein, FIC-1, that is responsible for phospholipid translocation across...

acid production. They do so by irreversibly inhibiting the stomach's H+/K+ ATPase proton pump. The body eventually synthesizes new proton pumps to replace...

M.; Block, B.A. (16 October 2003). "Temperature dependence of the Ca2+-ATPase (SERCA2) in the ventricles of tuna and mackerel". American Journal of Physiology...

region located at the C terminus of the BAG-family proteins that binds the ATPase domain of Hsc70/Hsp70. The BAG domain is evolutionarily conserved, and BAG...

PMC 1083955. PMID 11463741. Nishi T, Forgac M (Feb 2002). "The vacuolar (H+)-ATPases--nature's most versatile proton pumps". Nature Reviews Molecular Cell Biology...

disrupts the function of the heart by blocking its sodium and potassium ATPase. Cerberin can be used as a treatment for heart failure and arrhythmia. Overconsumption...

between mitochondrial, chloroplast and bacterial F-ATPases. In bacterial and chloroplast F-ATPases, the peripheral stalk is composed of one copy of the...

"Functional coupling between ryanodine receptors, mitochondria and Ca(2+) ATPases in rat submandibular acinar cells". Cell Calcium. 43 (5): 469–481. doi:10...

of single human skeletal muscle fibres demonstrates a relation between mATPase and MyHC expression in pure and hybrid fibre types". J. Muscle Res. Cell...

that contains the virion inside it. The endosome is acidified by cellular vATPase to have lower pH, which triggers a conformational change in HA that allows...

ryanodine receptors. Suramin is also an inhibitor of ABC-type and P-type ATPases, which acts competitively with ATP. Suramin was studied as a possible treatment...

problems, among many others the structure and function studies of the p97 ATPase and also p47, the DNA repair systems in Neisseria such as the AP endonuclease...

are mostly Na+, Cl−, K+, Ca2+ and HCO3−. The powering force is the Na/K-ATPase on the basolateral membrane which maintains the ion concentrations inside...

similarity to the SWI/SNF chromatin remodeling family in the ATPase domain. Outside the ATPase domain ISWI loses the similarity with the member of the SWI/SNF...

cardiac glycoside and, as such, blocks the heart's sodium and potassium ATPase. One kernel contains a fatal dose of the toxin. Electrocardiographic abnormalities...

increases sodium delivery to the collecting ducts and reduces sodium-potassium ATPase activity, limiting sodium and water reabsorption. The increased sodium in...

the useful molecule for contraction demands, ATP, an action performed by ATPase in the myofibril. The resulting creatine product acts as a signal molecule...

hereditary causes include mutations of subunits of the apical proton pump vH+-ATPase, which are transmitted in an autosomal recessive fashion, and may be associated...

2004). "Paying the price at the pump: dystonia from mutations in a Na+/K+ -ATPase". Neuron. 43 (2): 153–154. doi:10.1016/j.neuron.2004.07.002. PMID 15260948...

In enzymology, a capsular-polysaccharide-transporting ATPase (EC 7.6.2.2) is an enzyme that catalyzes the chemical reaction ATP + H2O + capsular polysaccharidein...

includes the expression of the calcium ATPase, regulation of ion channels, oxidative phosphorylation, increased Na-K-ATPase activity, increased carbohydrate...

protein ArlH inhibits oligomerization and interaction with ArlI, the motor ATPase of the archaellum". Molecular Microbiology. 116 (3): 943–956. doi:10.1111/mmi...

translocation in enterocytes; ATP2B1 (PMCA1b), a plasma membrane calcium ATPase involved in calcium extrusion from the cell; and the S100A family of genes...

"Effect of cinnamon, clove and some of their constituents on the Na(+)-K(+)-ATPase activity and alanine absorption in the rat jejunum". Food and Chemical Toxicology...

responsible for muscle contraction, transport in the cell, energy generation (F1-ATPase), DNA replication and transcription (polymerases), DNA unknotting and unwinding...

hippocampal development. Glucocorticoids stimulate the maturation of the Na+/K+/ATPase, nutrient transporters, and digestion enzymes, promoting the development...

function nucleotide binding protein binding hydrolase activity ATP binding ATPase activity GTPase activity GTP binding protein kinase binding Cellular component...

of proteins that use ATP are P-type ATPases that transfer Na+, K+, and Ca2+ ions by phosphorylation, A-type ATPases that transfer anions, and ABC transporters...

used in heart failure, inhibits the activity of the carrier molecule, Na-K-ATPase pump. The widest class of drugs act as ligands that bind to receptors that...

80 mg/kg. It is a GABA-gated chloride channel antagonist, and a Ca2+, Mg2+ ATPase inhibitor. Both of these enzymes are involved in the transfer of nerve impulses...

two types, ClpP, with peptidase activity, and the protein ClpA, with AAA+ ATPase activity. ClpP and ClpA are not evolutionarily related. A fully assembled...

sufficient (d)ATP/ATP. The ATPase domain belongs to the AAA+ family of ATPases; this family is known for its ability to link to other ATPase domains and form hexa-...

mediated by a sodium–iodine symporter and is linked to a sodium-potassium ATPase. Perchlorate and thiocyanate are drugs that can compete with iodine at this...

Hallström BM, Säll T, Broberg K (August 2019). "Evolution of P2A and P5A ATPases: ancient gene duplications and the red algal connection to green plants...

glycosides like digoxin, primarily inhibit the sodium-potassium pump (Na+/K+ ATPase), an important protein located on the surface of cardiomyocytes (cardiac...

Cu+-exporting ATPase EC 3.6.3.55: Now EC 7.3.2.6, tungstate-importing ATPase EC 3.6.4.1: Now EC 5.6.1.8, myosin ATPase EC 3.6.4.2: Now EC 5.6.1.2, dynein ATPase EC...

replication factor C (RFC) complex. The RFC complex is composed of five ATPases: Rfc1, Rfc2, Rfc3, Rfc4 and Rfc5. RFC recognizes primer-template junctions...

segment and introduction of 2 negative supercoils. N-gates are formed by ATPase domains of GyrB subunits. Binding of 2 ATP molecules leads to dimerization...

(born 1918), Nobel laureate in chemistry (1997) for his discovery of Na+,K+-ATPase Hans H. Ørberg (1920–2010), linguist and scholar Aage Bohr (1922–2009),...

Category:EC 3.6.1 Helicase DnaB helicase RecQ helicase Category:EC 3.6.3 ATPase NaKATPase (EC 3.6.3.9) ATP synthase (EC 3.6.3.14) Kynureninase EC 3.7.1...

(2019). "Hyperacidification of Citrus fruits by a vacuolar proton-pumping P-ATPase complex". Nature Communications. 10 (1): 744. Bibcode:2019NatCo..10..744S...

parkinsonism: cinnarizine and flunarizine are potent uncouplers of the vacuolar H+-ATPase in catecholamine storage vesicles". Neuropharmacology. 38 (6): 879–82. doi:10...

2006). "The Rad51/RadA N-terminal domain activates nucleoprotein filament ATPase activity". Structure. 14 (6). London, England: 983–992. doi:10.1016/j.str...

including MinD and Get3, has shifted in substrate specificity to become ATPases. For a discussion of Translocation factors and the role of GTP, see signal...

In enzymology, an oligosaccharide-transporting ATPase (EC 3.6.3.18) is an enzyme that catalyzes the chemical reaction ATP + H2O + oligosaccharideout ⇌...

is sufficient to support essential mitotic functions. Condensin exhibits ATPase activity and utilizes the energy from ATP hydrolysis to form DNA loops....

(2005). "Interactions between cardiac glycosides and sodium ⁄ potassium-ATPase: three-dimensional structure)activity relationship models for ligand binding...

of asteroid P-type semiconductor MG P-type, a type of automobile P-type ATPase, evolutionarily related ion and lipid pumps P-Type (rapper), a South Korean...

also transport cargo around the cell as part of the cytoskeleton. Other ATPases in the cell membrane are ion pumps involved in active transport. Enzymes...

focusing in immobilized pH gradients. Its effects on dog kidney Na+/K+-ATPase and rat brain GABA receptors have also been studied. ADA does, however,...

March 2019. Richardson JP (September 2002). "Rho-dependent termination and ATPases in transcript termination". Biochimica et Biophysica Acta (BBA) - Gene...

histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases...

pregnancy and breastfeeding is of unclear safety. It works by blocking H+/K+-ATPase in the parietal cells of the stomach. Lansoprazole was patented in 1984...

this gene is a member of the AAA family of adenosine triphosphatases (ATPases), is related to the Clp protease/heat shock family. Mutations in this gene...

to see hsp104 in multicellular animals. Hsp104 is classified as a. AAA+ ATPases and a subgroup of Hsp100/Clp, because of the usage of Atp hydrolysis for...

Calcium-ATPases decreases intracellular calcium concentration by pumping calcium ions to the outside of the cell (this allows for the H+-ATPase to be reactivated...

influx of water that causes cellular swelling. After the failure of the ATPase pumps, free radicals form and cause damage that complicates the edema. Evidence...

proteins activate the auto-inhibited plasma membrane P-type H+ ATPases. They bind the ATPases' C-terminus at a conserved threonine. Yang, X.; Lee, W. H.;...

of unknown function), zf-GRF domain, and AAA_11 and an AAA_12 domain (ATPases associated with diverse cellular activities). DUF domains are involved...

He discovered, named and characterised the founding member of the dynein ATPase family of motor proteins and other microtubular components in cilia and...

in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase". Proceedings of the National Academy of Sciences. 109 (32): 13040–13045...

In enzymology, a phosphonate-transporting ATPase (EC 3.6.3.28) is an enzyme that catalyzes the chemical reaction ATP + H2O + phosphonateout ⇌ {\displaystyle...

excitability are voltage-gated ion channels, ion transporters (e.g. Na+/K+-ATPase, magnesium transporters, acid–base transporters), membrane receptors and...

are classified under EC number 3.6. Well known members of this class are ATPase and GTPase. List of EC numbers (EC 3)#EC 3.6: Acting on acid anhydrides...

Another example of the importance of reaction intermediates is seen with AAA-ATPase p97, a protein that used in a variety of cellular metabolic processes. p97...

enteric infections Function Transporter Absorption NHE, SGLT1, ENaC, DRA Secretion CaCC, NKCC1, CFTR Absorption and secretion Sodium potassium ATPase...

domain of eIF4A and the central domain of eIF4G modulates RNA-stimulated ATPase activity". The Journal of Biological Chemistry. 280 (3): 1872–81. doi:10...

there is evidence for homology of the central subunits of transmembrane ATPases throughout all living organisms, especially how the rotating elements are...

in transmembrane segment 6 is common for all heavy metal transporting ATPases. Between transmembrane segments 6 and 7 is a large cytoplasmic loop, where...

containing antacids or colestyramine Digitoxin inhibits the sodium-potassium ATPase in heart muscle cells, resulting in increased force of contractions (positive...

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 is a protein in humans that is encoded by the ATP6V0D2 gene. It is part of proton pumps in the...

(steroid-exporting) may refer to: Steroid-transporting ATPase, an enzyme Xenobiotic-transporting ATPase, an enzyme This set index page lists enzyme articles...

Goffredi SK, Childress JJ (2001). "Activity and inhibitor sensitivity of ATPases in the hydrothermal vent tubeworm Riftia pachyptila: a comparative approach"...

animal model of hypertension. It modulates the effects of the enzyme Na+/K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes...

and the associated unusual blood group phenotype Rhnull; Na+/K+ – ATPase; Ca2+ – ATPase; Na+ K+ 2Cl− – cotransporter; Na+-Cl− – cotransporter; Na-H exchanger;...

myogenesis. Unlike calponin 1, calponin 3 has little effect on actomyosin Mg2+-ATPase activity and does not cause actin filaments bundling at the same condition...

lactoferrin by trypsin, the peptide lactoferricin is produced which binds to H+-ATPase, disrupting proton translocation and ultimately killing the cell. Ferritin...

"Mechanistic studies of phosphoserine phosphatase, an enzyme related to P-type ATPases". The Journal of Biological Chemistry. 274 (48): 33985–90. doi:10.1074/jbc...

help of BiP and other transport complexes, while in bacteria, the SecA ATPase provides the energy to push the peptide through the channel. In co-translational...

Tübingen, working for his final year at Dieter Oesterhelt's laboratory on ATPase activity of halobacteria. Michel later[when?] worked on the crystallisation...

is dependent on concentrations of Ca2+ in the cytosol, either via Ca,Mg-ATPase from the sarcoplasmic reticulum or voltage-gated calcium channels from the...

BioGPS More reference expression data Gene ontology Molecular function ATPase binding scaffold protein binding cAMP binding metal ion binding beta-2 adrenergic...

leads to downstream expression of Pitx2. At earlier stages, similar H+/K+ ATPase ion channels are reported to be necessary for correct left–right patterning...

electrophysiology and calcium imaging to characterize how plasma-membrane calcium-ATPase (PMCA) and Ca(2+) release-activated Ca(2+) (CRAC) channels regulate calcium...

In enzymology, a quaternary-amine-transporting ATPase (EC 3.6.3.32) is an enzyme that catalyzes the chemical reaction ATP + H2O + quaternary amineout ⇌...

of Biophysics in Pushchino. The first scientific papers were devoted to ATPases and the use of radioactive isotopes in experimental and clinical studies...

effectively binds ATP and allows hydrolysis of the energy molecule by most ATPases. Mn2+ can also replace Mg2+ as the activating ion for a number of Mg2+-dependent...

benzolactone from Myxobacteriais a novel selective inhibitor of mitochondrial F1-ATPases". FEBS Letters. 581 (18): 3523–3527. Bibcode:2007FEBSL.581.3523K. doi:10...

neurotransmitter receptors to postsynaptic cytoskeleton AT6V1D: V-type proton ATPase subunit D, an enzyme that mediates acidifcation of eukaryotic intracellular...

the electrical discharge. These organs are also rich in sodium potassium ATPase, an ion pump used to create a potential difference across cell membranes...

characterization has been performed for ArlI, a Type II/IV secretion system ATPase super-family member and PibD/ArlK. ArlI forms a hexamer which hydrolyses...

also affects intracellular molecules. It inhibits plasma membrane calcium ATPases (PMCAs) which affects membrane fluidity by hindering the flow of Ca2+ (calcium...

ontology Molecular function nucleotide binding ATP binding GTPase activity ATPase activity Cellular component plasma membrane extrinsic component of plasma...

of Upton and Murphy, which included new data from mtDNA cytochrome b and ATPase 6 sequences, the following species can be recognized pending further research:...

kinase, and Na+/K+-ATPase (synaptosomal membrane). Melittin blocks transport pumps such as the Na+-K+-ATPase and the H+-K+-ATPase. Melittin is the main...

lipids decreases the α-helix content in mitochondria and leads to changes in ATPase resembling uncompetitive inhibition. This presence of uncompetitive enzymes...

AAA ATPases (Subunit Rpt1-6, systematic nomenclature) and four non-ATPase subunits (Rpn1, Rpn2, Rpn10, and Rpn13). Protein 26S proteasome non-ATPase regulatory...

PMID 14573461. Richardson JP (September 2002). "Rho-dependent termination and ATPases in transcript termination". Biochimica et Biophysica Acta (BBA) - Gene...

generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains or parts: F1, which contains the catalytic...

capsid. Singelavirians also encode a genome packaging ATPase of the FtsK-HerA superfamily. The ATPases in Singelaviria are enzymes that package the viral...

glands in exchange for K+. Aldosterone stimulates secretion of H+ via the H+/ATPase in the intercalated cells of the cortical collecting tubules Aldosterone...

bloodstream. Potassium is not in fact lost from the body, but increased Na+/K+-ATPase activity (the enzyme that moves potassium into cells and keeps sodium in...

the membrane potential of the cell is maintained by the sodium-potassium ATPase pump. Failure of the pump results in loss of membrane potential as sodium...

triphosphate (ATP)" John E. Walker (b. 1941) British Jens C. Skou (1918–2018) Danish "for the first discovery of an ion-transporting enzyme, Na+, K+ -ATPase"...

ontology Molecular function ATP binding nucleotide binding ATPase activity microtubule-severing ATPase activity Cellular component nucleus Biological process...

(October 1989). "Corticosteroid action on choroid plexus: Reduction in Na+?K+-ATPase activity, choline transport capacity, and rate of CSF formation". Experimental...

; Mori, A.; Savitzky, A.H. (2016). "Toxin-resistant isoforms of Na+/K+-ATPase in snakes do not closely track dietary specialization on toads". Proceedings...

that is needed for the secretion of gastric acid. It is a specific H+/K+ATPase inhibitor. This is the enzyme needed for the final step in the secretion...

Hsp70 and Hsp90. They are particularly essential in stimulation of the ATPase activity of these chaperone proteins. There are a great number of different...

retention and a shift in intracellular sodium transport from inhibition of Na/K ATPase. Hypoglycaemia (due to depleted hepatic glycogen store and hyperinsulinaemia)...

Fluoroberyllium Complexes as Probes of the Catalytic Sites of Mitochondrial F1-ATPases. UNESCO. pp. 59–69. ISBN 9783034873154. {{cite book}}: |work= ignored (help)...

e. proportional to its volume (hence "V") to the power zero (hence "0") ATPase, H+ transporting, lysosomal V0 subunit a1, a human gene The highest standard...

Danish "for the first discovery of an ion-transporting enzyme, Na+, K+ -ATPase" 1998 Walter Kohn (1923–2016) Austrian American "for his development of...

than DDT, and strong evidence indicates that p,p'-DDE inhibits calcium ATPase in the membrane of the shell gland and reduces the transport of calcium...

encoded by this gene is a component of the F-type ATPase found in the mitochondrial matrix. F-type ATPases are composed of a catalytic core and a membrane...

(ATP). These calcium pumps are called Sarco(endo)plasmic reticulum Ca2+ ATPases (SERCA). There are various forms of SERCA, with SERCA 2a being predominantly...

In enzymology, an iron-chelate-transporting ATPase (EC 3.6.3.34) is an enzyme that catalyzes the chemical reaction ATP + H2O + iron chelateout ⇌ {\displaystyle...

the mitochondrial ATP synthase (complex V), as well as the lysosomal V-ATPase. The protein is associated with the ATP synthase in a stoichiometric manner...

reticulum calcium ATPase 3 is an enzyme that in humans is encoded by the ATP2A3 gene. This gene encodes one of the SERCA Ca2+-ATPases, which are intracellular...

activate, or inhibit, mTORC1. The Ragulator, along with the Rag GTPases and v-ATPases, are part of an amino acid identifying pathway, and are necessary for the...

Sensitivity of Myosin ATPase to acid and alkali: I (Slow oxidative, SO) — Low glycolytic and high oxidative presence. Low(er) myosin ATPase, sensitive to alkali...

through covalent bonds. Dapansutrile targets the inhibition of the NLRP3 ATPase and thus blocks the activation of the inflammasome's ASC, and caspase-1...

transport mechanisms that respond to osmoregulatory loads. Sodium-Potassium ATPase works with a Sodium-Chloride cotransporter (also known as the NKCC), and...

function microtubule binding microtubule motor activity nucleotide binding ATPase activity ATP binding minus-end-directed microtubule motor activity Cellular...

by inhibiting synthesis of DNA and RNA or of some key enzymes, such as ATPases and phosphotransferases, in some bacterial species. Propylparaben is considered...

biogenesis: Recent insights into the roles of frataxin, acyl carrier protein and ATPase-mediated transfer to recipient proteins". Current Opinion in Chemical Biology...

replication protein A (RPA1, RPA2, RPA3), transitional endoplasmic reticulum ATPase (VCP), and RNA polymerase III initiation factor (BRF2) using affinity capture...

(IKATP) and Ito. At micromolar concentrations, quinidine inhibits Na+/K+-ATPase by binding to the same receptor sites as the digitalis glycosides such as...

cream. Adenosine monophosphate Adenosine diphosphate Adenosine triphosphate ATPase ATP hydrolysis ATP synthase Biochemistry Bone Calcium pyrophosphate Calcium...

interact with Na+-K+ ATPase through its cardiotonic steroid binding site. The binding of cassaine to this site inhibits ATPase. Cassaine can be defined...

Ronquist G (June 1987). "Effect of modulators on prostasome membrane-bound ATPase in human seminal plasma". European Journal of Clinical Investigation. 17...

Probable phospholipid-transporting ATPase IIA is a protein that in humans is encoded by the ATP9A gene. GRCh38: Ensembl release 89: ENSG00000054793 – Ensembl...

include NRF1, NR2C2, ELK4, ETV4, TFAP2A, and IRF3. PAAT functions as a novel ATPase, catalyzing ATP hydrolysis to regulate iron homeostasis. It contains two...

rhizome. Sanguinarine kills animal cells by blocking the action of Na+/K+-ATPase transmembrane proteins. As a result, applying bloodroot to the skin may...

(April 1993). "Cloning of a Ca(2+)-ATPase gene of Plasmodium falciparum and comparison with vertebrate Ca(2+)-ATPases". Journal of Cell Science. 104 ( Pt...

to digest their food. Like echinoderms, hagfish lack hydrogen potassium ATPase, an enzyme that acidifies true stomachs. Recent studies have shown that...

July 9, 2026. Erb, Anthony L.; Young-Baird, Sara K. (2026). "CDC123 is an ATPase that modulates mRNA translation and the integrated stress response by regulating...

simultaneously for reduction to occur. ArsA and ArsB form an anion-translocating ATPase. The ArsB protein is distinguished by its overall hydrophobic character...

S, Schulten K (October 2003). "On the mechanism of ATP hydrolysis in F1-ATPase". Biophysical Journal. 85 (4): 2253–66. Bibcode:2003BpJ....85.2253D. doi:10...

cells together. Cytokinetic furrow ingression is powered by Type II Myosin ATPase. Since Myosins are recruited to the medial region, the contractile forces...

More reference expression data BioGPS n/a Gene ontology Molecular function ATPase binding protein binding Cellular component lysosome mitochondrion cytosol...

of sodium. Sodium's electrochemical gradient is established by the Na/K-ATPase, which is an ATP-dependent enzyme. Since NKCC proteins use sodium's gradient...

defined by being consistently located upstream of malK genes, which encode an ATPase that is used by transporters whose ligand is likely a kind of sugar. Most...

ARGLU1: encoding protein Arginine and glutamate-rich protein 1 ATP7B: ATPase, Cu++ transporting, beta polypeptide (Wilson disease) BRCA2: breast cancer...

(Drosophila melanogaster) N9, N10, N11 Intein-containing V-type proton ATPase catalytic subunit A (Saccharomyces cerevisiae) PE clan P1 DmpA aminopeptidase...

In enzymology, a monosaccharide-transporting ATPase (EC 3.6.3.17) is an enzyme that catalyzes the chemical reaction ATP + H2O + monosaccharideout ⇌ {\displaystyle...

More reference expression data BioGPS n/a Gene ontology Molecular function ATPase binding sodium channel regulator activity ion channel activity potassium...

the extracellular fluid. This is accomplished in all animals by Na+/K+-ATPase, an active transporter pumping ions against the gradient, and sodium/potassium...

Nucleolin NR4A2: nuclear receptor subfamily 4, group A, member 2 OLA1: Obg-like ATPase 1 PARD3B encoding protein Partitioning defective 3 homolog B PAX3: paired...

Dmitriev OY (2007). "Function and Regulation of Human Copper-Transporting ATPases". Physiological Reviews. 87 (3): 1011–46. doi:10.1152/physrev.00004.2006...

contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar...

Ouabain and digitoxin. It specifically inhibits the membrane protein Na+/ K+ ATPase in muscle tissue (heart) which can lead to Ca2+ overload, diastolic dysfunction...

similarity to ATPase domains, dimeric HPt proteins have not been shown to bind or hydrolyze ATP and lack key residues present in other ATPases. The monomeric...

reference expression data Gene ontology Molecular function nucleotide binding ATPase activity protein homodimerization activity transmembrane transporter activity...

function microtubule binding microtubule motor activity nucleotide binding ATPase activity cytoskeletal motor activity protein binding ATP binding RNA binding...

exchanger 3, aquaporin 7, sodium-iodide symporter and hydrogen potassium ATPase) showed reduced expression or mislocalization in all patients with different...

Program [1] Garg LC, Narang N (1989). "Suppression of ouabain-insensitive K-ATPase activity in rabbit nephron segments during chronic hyperkalemia". Renal...

(October 2004). "Characterization of the P5 subfamily of P-type transport ATPases in mice". Biochemical and Biophysical Research Communications. 323 (3):...

dephosphorylation of ATPases determines the flow of ions into and out of the cell. Proton pump inhibitors are a class of drug that acts directly on ATPases of the gastrointestinal...

complex I and cryo-EM maps of mitochondrial complex I and vacuolar type ATPases. Many students and postdoctoral research fellows who studied with John...

Sodium/potassium-transporting ATPase gamma chain is a protein that in humans is encoded by the FXYD2 gene. This gene encodes a member of a family of small...

FO complex E subunit appears to play an important role in supporting F-ATPase dimerisation. This subunit is anchored to the inner mitochondrial membrane...

(aquaporins) and membrane proteins which move solutes across a cell membrane (H+ - ATPase) allows for the rapid flux of water out of these motor cells. Water flux...

plasma. This possibly occurs via insulin-induced translocation of the Na+/K+-ATPase to the surface of skeletal muscle cells. Decreased renal sodium excretion...

occurs in the globular head domains, which share similarities with the AAA+ (ATPase associated with various cellular activities) protein family. ATP hydrolysis...

GTPases Rab5 and Rab7, Annexin A2 (previously named Annexin II), the vacuolar ATPase, COP coat proteins, the N-ethylmaleimide sensitive factor, the small transmembrane...

barrier because it can substitute for calcium ions and be taken up by calcium-ATPase pumps. Lead poisoning interferes with the normal development of a child's...

initiate tendril coiling. This cascade can activate plasma membrane H+-ATPase, which also plays a role in the contact coiling mechanism as a proton pump...

pregnancy and breastfeeding is of unclear safety. It works by blocking H+/K+-ATPase in the parietal cells of the stomach. Rabeprazole was patented in 1986,...

secretion systems and second-stalk components of the FoF1 and vacuolar ATPases". Protein Science. 15 (4): 935–941. doi:10.1110/ps.051958806. PMC 2242474...

transmembrane transporter activity ATPase activity ATP binding purine nucleotide transmembrane transporter activity ATPase-coupled inorganic anion transmembrane...

Nomura, Daniel K. (August 2019). "Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition". Nature Chemical Biology. 15...

function protein homodimerization activity protein domain specific binding ATPase binding protein kinase A binding cytoskeletal protein binding protein binding...

acid by blocking an enzyme involved in its production (hydrogen potassium ATPase), and their effects last much longer than H2RAs—around 16 to 18 hours. They...

pregnancy and breastfeeding is of unclear safety. It works by blocking H+/K+-ATPase in the parietal cells of the stomach. Dexlansoprazole was approved for medical...

permeant ion) but, as per the pump-leak model, it is extruded by the Na+/K+-ATPase. Because there is a difference in concentration of ions on either side of...

Tan M, Tan U, Gunel M, Ozcelik T (March 2013). "Missense mutation in the ATPase, aminophospholipid transporter protein ATP8A2 is associated with cerebellar...

In enzymology, an Ag+-exporting ATPase (EC 7.2.2.15) is an enzyme that catalyzes the chemical reaction ATP + H2O + Ag+in ⇌ {\displaystyle \rightleftharpoons...