AHSA2

AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast)
Identifiers
SymbolAHSA2
Alt. symbolsHch1
NCBI gene130872
HGNC20437
RefSeqNM_152392
UniProtQ719I0
Other data
LocusChr. 2 p14
Search for
StructuresSwiss-model
DomainsInterPro

AHSA2 also known as AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) is a human gene which encodes a protein which acts as co-chaperone of Hsp90 (heat shock protein 90).[1] AHSA2 and the related AHSA1 belongs to the AHA (Activator of Hsp90 ATPase) family of stress-regulated proteins that bind directly to Hsp90 and are required for Hsp90-dependent activation of client proteins.[1]

References

  1. ^ a b Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C (December 2002). "Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1" (PDF). Mol. Cell. 10 (6): 1307–18. doi:10.1016/S1097-2765(02)00785-2. PMID 12504007.


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