STAT-2

STAT-2 (bahasa Inggris: signal transducer and activator of transcription 2, P113; ISGF-3; STAT113; MGC59816; STAT2) adalah faktor transkripsi dengan massa 113 kDA dari keluarga STAT.[1]

Saat terstimulasi sitokina maupun faktor pertumbuhan, STAT-2 terfosforilasi oleh kinase tertentu dan membentuk homodimer atau heterdimer, sebelum bermigrasi ke dalam inti sel dan berfungsi sebagai faktor transkripsi. Saat terstimulasi IFN, STAT-2 membentuk kompleks dengan STAT-1 dan ISGF3G.

Rujukan

  1. ^ (Inggris) "STAT2 signal transducer and activator of transcription 2, 113kDa [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-10-24.


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