Angka reproduksi dasar

**Nilai R₀ penyakit menular terkenal**^[1]
Penyakit	Transmisi	R₀
Campak	Udara	12–18
Difteri	Air liur	6-7
Smallpox	Partikel air kecil di udara	5–7
Polio	Rute tinja-oral	5–7
Rubella	Partikel air kecil di udara	5–7
Beguk	Partikel air kecil di udara	4–7
HIV/AIDS	Hubungan seksual	2–5
Batuk rejan	Partikel air kecil di udara	5,5^[2]
COVID-19	Partikel air kecil di udara	3-5^[3]
SARS	Partikel air kecil di udara	2–5^[4]
Influenza (Flu Spanyol)	Partikel air kecil di udara	2–3^[5]
Ebola (Wabah virus Ebola 2014)	Cairan tubuh	1,5-2,5^[6]

Dalam epidemiologi, Angka reproduksi dasar (kadang-kadang disebut rasio reproduksi dasar, atau walaupun tidak tepat disebut tingkat reproduksi dasar, dan dinotasikan R₀, r nought) dari infeksi dapat dianggap sebagai jumlah kasus yang dihasilkan oleh satu kasus secara rata-rata selama periode menularnya, dalam populasi yang tidak terinfeksi.^[7]

Metrik ini berguna karena membantu menentukan apakah suatu penyakit infeksi dapat menyebar dalam suatu populasi. Akar konsep reproduksi dasar dapat ditelusuri melalui karya Alfred Lotka, Ronald Ross, dan lainnya, tetapi aplikasi modern pertama dalam epidemiologi adalah karya George MacDonald pada tahun 1952, yang membangun model populasi dari penyebaran malaria.

Jika

R₀ < 1

infeksi akan berhenti dalam jangka panjang. Namun, jika

R₀ > 1

infeksi akan dapat menyebar dalam suatu populasi.

Secara umum, semakin besar nilai R₀, semakin sulit untuk mengendalikan epidemi.

Referensi

^ Unless noted R₀ values are from: History and Epidemiology of Global Smallpox Eradication Diarsipkan 2016-05-10 di Wayback Machine. From the training course titled "Smallpox: Disease, Prevention, and Intervention". The CDC and the World Health Organization. Slide 16-17.
^ Kretzschmar M, Teunis PF, Pebody RG (2010). "Incidence and reproduction numbers of pertussis: estimates from serological and social contact data in five European countries". PLoS Med. 7 (6): e1000291. doi:10.1371/journal.pmed.1000291. PMC 2889930 . PMID 20585374.
^ Zhao, Shi; Ran, Jinjun; Musa, Salihu Sabiu; Yang, Guangpu; Lou, Yijun; Gao, Daozhou; Yang, Lin; He, Daihai (2020-01-24). "Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak". bioRxiv (dalam bahasa Inggris): 2020.01.23.916395. doi:10.1101/2020.01.23.916395.
^ Wallinga J, Teunis P (2004). "Different epidemic curves for severe acute respiratory syndrome reveal similar impacts of control measures". Am. J. Epidemiol. 160 (6): 509–16. doi:10.1093/aje/kwh255. PMID 15353409. Diarsipkan dari versi asli tanggal 2007-10-06.
^ Mills CE; Robins JM; Lipsitch M (2004). "Transmissibility of 1918 pandemic influenza". Nature. 432 (7019): 904–6. Bibcode:2004Natur.432..904M. doi:10.1038/nature03063. PMID 15602562.
^ Althaus, Christian L. (2014). "Estimating the Reproduction Number of Ebola Virus (EBOV) During the 2014 Outbreak in West Africa". PLoS Currents. 6. doi:10.1371/currents.outbreaks.91afb5e0f279e7f29e7056095255b288. PMC 4169395 . PMID 25642364.
^ Christophe Fraser; Christl A. Donnelly; Simon Cauchemez; et al. (19 June 2009). "Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings". Science. 324 (5934): 1557–1561. Bibcode:2009Sci...324.1557F. doi:10.1126/science.1176062. PMC 3735127 . PMID 19433588. Free text

[Smallpox-1] Unless noted R₀ values are from: History and Epidemiology of Global Smallpox Eradication Diarsipkan 2016-05-10 di Wayback Machine. From the training course titled "Smallpox: Disease, Prevention, and Intervention". The CDC and the World Health Organization. Slide 16-17.

[2] Kretzschmar M, Teunis PF, Pebody RG (2010). "Incidence and reproduction numbers of pertussis: estimates from serological and social contact data in five European countries". PLoS Med. 7 (6): e1000291. doi:10.1371/journal.pmed.1000291. PMC 2889930 . PMID 20585374.

[3] Zhao, Shi; Ran, Jinjun; Musa, Salihu Sabiu; Yang, Guangpu; Lou, Yijun; Gao, Daozhou; Yang, Lin; He, Daihai (2020-01-24). "Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak". bioRxiv (dalam bahasa Inggris): 2020.01.23.916395. doi:10.1101/2020.01.23.916395.

[4] Wallinga J, Teunis P (2004). "Different epidemic curves for severe acute respiratory syndrome reveal similar impacts of control measures". Am. J. Epidemiol. 160 (6): 509–16. doi:10.1093/aje/kwh255. PMID 15353409. Diarsipkan dari versi asli tanggal 2007-10-06.

[5] Mills CE; Robins JM; Lipsitch M (2004). "Transmissibility of 1918 pandemic influenza". Nature. 432 (7019): 904–6. Bibcode:2004Natur.432..904M. doi:10.1038/nature03063. PMID 15602562.

[6] Althaus, Christian L. (2014). "Estimating the Reproduction Number of Ebola Virus (EBOV) During the 2014 Outbreak in West Africa". PLoS Currents. 6. doi:10.1371/currents.outbreaks.91afb5e0f279e7f29e7056095255b288. PMC 4169395 . PMID 25642364.

[Fraser-7] Christophe Fraser; Christl A. Donnelly; Simon Cauchemez; et al. (19 June 2009). "Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings". Science. 324 (5934): 1557–1561. Bibcode:2009Sci...324.1557F. doi:10.1126/science.1176062. PMC 3735127 . PMID 19433588. Free text

[1]

[2]

[3]

[4]

[5]

[6]

[7]