DOSEN PROFIL LENGKAP

above. Common names are also sometimes formed as "acceptor reductase", such as NAD+ reductase. "Donor oxidase" is a special case where O2 is the acceptor...

5α-Reductase 2 deficiency (5αR2D) is an autosomal recessive condition caused by mutations impairing the function of SRD5A2, a gene located on chromosome...

5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used...

Steroid reductases are reductase enzymes that are involved in steroid biosynthesis and metabolism. They include: 5α-Reductase 5β-Reductase Steroidogenic...

5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. They participate in three metabolic pathways:...

well as the production of sebum and body hair composition. The enzyme 5α-reductase catalyzes the formation of DHT from testosterone in certain tissues including...

Statins (or HMG-CoA reductase inhibitors) are a class of medications that lower cholesterol. They are typically prescribed to people who are at high risk...

reductase (MTHFR) is the rate-limiting enzyme in the methyl cycle, and it is encoded by the MTHFR gene. Methylenetetrahydrofolate reductase catalyzes...

HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-limiting enzyme (NADH-dependent, EC 1.1.1.88;...

Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as an electron donor, which can be...

Nitrate reductases are molybdoenzymes that reduce nitrate (NO− 3) to nitrite (NO− 2). This reaction is critical for the production of protein in most crop...

Glutathione reductase (GR) also known as glutathione-disulfide reductase (GSR) is an enzyme that in humans is encoded by the GSR gene. Glutathione reductase (EC...

Fumarate reductase is the enzyme that converts fumarate to succinate, and is important in microbial metabolism as a part of anaerobic respiration. The...

reductase may refer to: Ferredoxin—NADP(+) reductase (FNR) Ferredoxin—NAD(+) reductase Ferredoxin—nitrite reductase Ferredoxin-thioredoxin reductase This...

exposure by acting specifically on hair follicles. Finasteride is a 5α-reductase inhibitor and therefore an antiandrogen. It works by decreasing the production...

TMAO reductase may refer to: Trimethylamine N-oxide reductase Trimethylamine-N-oxide reductase (cytochrome c) This set index page lists enzyme articles...

In enzymology, aldose reductase (or aldehyde reductase) (EC 1.1.1.21) is an enzyme in humans encoded by the gene AKR1B1. It is an cytosolic NADPH-dependent...

Benzil reductase may refer to: Benzil reductase ((R)-benzoin forming) Benzil reductase ((S)-benzoin forming) This set index page lists enzyme articles...

Glyoxylate reductase (EC 1.1.1.26), first isolated from spinach leaves, is an enzyme that catalyzes the reduction of glyoxylate to glycolate, using the...

Acetylmethionine sulfoxide reductase may refer to either: Methionine-S-oxide reductase L-methionine (S)-S-oxide reductase This set index page lists enzyme...

Thioredoxin reductases (TR, TrxR) (EC 1.8.1.9) are enzymes that reduce thioredoxin (Trx). Two classes of thioredoxin reductase have been identified: one...

Flavin reductase a class of enzymes. There are a variety of flavin reductases, (i.e. FRP, FRE, FRG, etc.) which bind free flavins and through hydrogen...

An imine reductase (IRED) is an enzyme that reduces imines to amines. This family of enzymes is employed in the industrial production of amine-containing...

Ribonucleotide reductase (RNR), also known as ribonucleoside diphosphate reductase, is an enzyme that catalyzes the formation of deoxyribonucleotides...

Arsenate reductase may refer to: Arsenate reductase (azurin) Arsenate reductase (cytochrome c) Arsenate reductase (donor) Arsenate reductase (glutaredoxin)...

Biliverdin reductase (BVR) is an enzyme (EC 1.3.1.24) found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver...

Perchlorate reductase is an enzyme that catalyzes the chemical reactions: ClO4− + 2 AH2 ⇌ {\displaystyle \rightleftharpoons } ClO2− + 2 A + 2 H2O and...

In enzymology, a ferric-chelate reductase (EC 1.16.1.7) is an enzyme that catalyzes the chemical reaction 2 Fe(II) + NAD+ ⇌ {\displaystyle \rightleftharpoons...

Reductase kinase may refer to: Dephospho-(reductase kinase) kinase, an enzyme AMP-activated protein kinase, an enzyme This disambiguation page lists articles...

Biliverdin reductase B is a protein that in humans is encoded by the BLVRB gene. The BLVRB gene was localized to chromosome 19, the specific region being...

Nitrite reductase refers to any of several classes of enzymes that catalyze the reduction of nitrite. There are two classes of NIRs. A multi heme enzyme...

In enzymology, an FMN reductase (EC 1.5.1.29) is an enzyme that catalyzes the chemical reaction FMNH2 + NAD(P)+ ⇌ {\displaystyle \rightleftharpoons }...

DMSO reductase is a molybdenum-containing enzyme that catalyzes reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS). This enzyme serves as...

Aldo-keto reductase family 1 member C2, also known as bile acid binding protein, 3α-hydroxysteroid dehydrogenase type 3 (3α-HSD3), and dihydrodiol dehydrogenase...

Diacetyl reductase is the name of two acetoin forming enzymes: Diacetyl reductase ((R)-acetoin forming) Diacetyl reductase ((S)-acetoin forming) Acetoin...

Leucoanthocyanidin reductase (EC 1.17.1.3) (LAR, aka leucocyanidin reductase or LCR) is an enzyme that catalyzes several related chemical reduction steps...

7-Dehydrocholesterol reductase, also known as DHCR7, is a protein that in humans is encoded by the DHCR7 gene. The protein encoded by this gene is an...

reductase may also refer to: Nitrite reductase (NO-forming) Nitrite reductase (NAD(P)H) Cytochrome c nitrite reductase Ferredoxin—nitrite reductase Nitrate...

NADPH-dependent oxidoreductases, such as aldehyde reductase, aldose reductase, prostaglandin F synthase, xylose reductase, rho crystallin, and many others. All possess...

Aldo-keto reductase family 1 (AKR1) is a family of aldo-keto reductase enzymes that is involved in steroid metabolism. It includes the AKR1C and AKR1D...

Adrenodoxin reductase (Enzyme Nomenclature name: adrenodoxin-NADP+ reductase, EC 1.18.1.6), was first isolated from bovine adrenal cortex where it functions...

Respiratory nitrate reductase may refer to: Nitrate reductase (cytochrome) Nitrate reductase This set index page lists enzyme articles associated with...

Enoyl-acyl carrier protein reductase (ENR or FabI) (EC 1.3.1.9), is a key enzyme of the type II fatty acid synthesis (FAS) system. ENR is an attractive...

cortisone 5β-reductase, cortisone Δ4-5β-reductase, steroid 5β-reductase, testosterone 5β-reductase, Δ4-3-ketosteroid 5β-reductase, Δ4-5β-reductase, Δ4-hydrogenase...

Nitrate reductases are enzymes that reduce nitrate to nitrite. Nitrate reductase may also refer to: Nitrate reductase (cytochrome) Nitrate reductase (NADH)...

In enzymology, a carbonyl reductase (NADPH) (EC 1.1.1.184) is an enzyme that catalyzes the chemical reaction R-CO-R' + NADPH + H+ ⇌ {\displaystyle \rightleftharpoons...

Nitric oxide reductase, an enzyme, catalyzes the reduction of nitric oxide (NO) to nitrous oxide (N2O). The enzyme participates in nitrogen metabolism...

Methionine synthase reductase, also known as MSR, is an enzyme in humans that is encoded by the MTRR gene. It functions as the obligate reductase for methionine...

Fumarate reductase (quinol) (EC 1.3.5.1, QFR, FRD, menaquinol-fumarate oxidoreductase, quinol:fumarate reductase) is an enzyme with systematic name succinate:quinone...

(+)-pulegone reductase (EC 1.3.1.81) is an enzyme with systematic name (−)-menthone:NADP+ oxidoreductase. This enzyme catalises the following chemical...

blocking. 5α-Reductase inhibitors are inhibitors of the enzyme 5α-reductase, and are a type of specific androgen synthesis inhibitor. 5α-Reductase is an enzyme...

Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. Sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase; EC 1.1...

Ubiquinone reductase may refer to the following enzymes: NADH dehydrogenase NADH:ubiquinone reductase (non-electrogenic) This set index page lists enzyme...

Alcohol dehydrogenase [NADP+] also known as aldehyde reductase or aldo-keto reductase family 1 member A1 is an enzyme that in humans is encoded by the...

consistent findings on physical examination, the presence of anti HMG-CoA reductase antibodies in a person with myopathy, evidence of muscle breakdown, and...

The mevalonate pathway, also known as the isoprenoid pathway or HMG-CoA reductase pathway is an essential metabolic pathway present in eukaryotes, archaea...

Vinylphenol reductase is an enzyme that catalyses the reaction : 4-vinylphenol + NAD+ + 3 H+ ⇔ 4-ethylphenol + NADH It is found in Brettanomyces bruxellensis...

between 5α-reductase inhibitors and prostate cancer has been established. This is not due to a direct link between dutasteride or other 5α-reductase inhibitors...

dehydroascorbic reductase, dehydroascorbic acid reductase, glutathione dehydroascorbate reductase, DHA reductase, dehydroascorbate reductase, GDOR, and...

DPNH-ubiquinone reductase may refer to the following enzymes: NADH dehydrogenase NADH:ubiquinone reductase (non-electrogenic) This set index page lists...

In enzymology, a ferredoxin-NADP+ reductase (EC 1.18.1.2) abbreviated FNR, is an enzyme that catalyzes the chemical reaction 2 reduced ferredoxin + NADP+...

Cortisone reductase deficiency is caused by dysregulation of the 11β-hydroxysteroid dehydrogenase type 1 enzyme (11β-HSD1), otherwise known as cortisone...

Methylenetetrahydrofolate reductase deficiency is the most common genetic cause of elevated serum levels of homocysteine (hyperhomocysteinemia). It is...

In enzymology, Delta1-piperideine-2-carboxylate reductase (EC 1.5.1.21) is an enzyme that catalyzes the chemical reaction (-)-pipecolic acid + NADP+  ...

by the SRD5A1 gene. It is one of three forms of steroid 5α-reductase. Steroid 5α-reductase (EC 1.3.99.5) catalyzes, among other reactions, the conversion...

4-dehydrogenase 2 enzyme, also known as 5α-reductase type 2 (5αR2), one of three isozymes of 5α-reductase. 5αR2 catalyzes the conversion of the male sex...

Mercury(II) reductase (EC 1.16.1.1), commonly known as MerA, is an oxidoreductase enzyme and flavoprotein that catalyzes the reduction of Hg2+ to Hg0...

In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) is an enzyme that catalyzes the chemical reaction 3-oxoacyl-[acyl-carrier-protein](ACP)...

subsequently oxidized to fructose. It is also called the sorbitol-aldose reductase pathway. The pathway is implicated in diabetic complications, especially...

Cytochrome c reductase may refer to: Coenzyme Q – cytochrome c reductase, an enzyme Iron—cytochrome-c reductase NADH dehydrogenase, an enzyme This set...

Sulfite reductases (EC 1.8.99.1) are enzymes that participate in sulfur metabolism. They catalyze the reduction of sulfite to hydrogen sulfide and water...

called a reductase. E. coli can use fumarate reductase, nitrate reductase, nitrite reductase, DMSO reductase, or trimethylamine-N-oxide reductase, depending...

Dissimilatory sulfite reductase (EC 1.8.1.22) is an enzyme that participates in sulfur metabolism in dissimilatory sulfate reduction. The enzyme is essential...

In enzymology, a glycine reductase (EC 1.21.4.2) is an enzyme that catalyzes the chemical reaction acetyl phosphate + NH3 + thioredoxin disulfide + H2O...

In enzymology, protochlorophyllide reductases (POR) are enzymes that catalyze the conversion from protochlorophyllide to chlorophyllide a. They are oxidoreductases...

These enzymes also catalyze the reverse reaction, acting as ketosteroid reductases (KSRs). There are four types, classified by the number of the position...

Cytochrome-b5 reductase is a NADH-dependent enzyme that converts ferricytochrome from a Fe3+ form to a Fe2+ form. It contains FAD and catalyzes the reaction:...

Adenylyl-sulfate reductase (EC 1.8.99.2) is an enzyme that catalyzes the chemical reaction of the reduction of adenylyl-sulfate/adenosine-5'-phosphosulfate...

Morphinone reductase is an enzyme which catalyzes the NADH-dependent saturation of the carbon-carbon double bond of morphinone and codeinone, yielding...

NADPH-nitrate reductase, assimilatory NADPH-nitrate reductase, triphosphopyridine nucleotide-nitrate reductase, NADPH:nitrate reductase, nitrate reductase (NADPH2)...

In enzymology, a hydrogensulfite reductase (EC 1.8.99.3) is an enzyme that catalyzes the chemical reaction trithionate + acceptor + 2 H2O + OH- ⇌ {\displaystyle...

Mycothione reductase (EC 1.8.1.15) is an enzyme that catalyzes the chemical reaction mycothione + NAD(P)H + H+ ⇌ {\displaystyle \rightleftharpoons } 2...

Sulfoacetaldehyde reductase (EC 1.1.1.313, ISFD) is an enzyme with systematic name isethionate:NADP+ oxidoreductase. This enzyme catalyses the following...

In enzymology, a chlorate reductase (EC 1.97.1.1) is an enzyme that catalyzes the chemical reaction AH2 + chlorate ⇌ {\displaystyle \rightleftharpoons...

Dimethylsulfone reductase (EC 1.8.1.17) is an enzyme that catalyses the following chemical reaction dimethyl sulfone + NADH     H+ H2O H+ H2O   dimethyl...

Biliverdin reductase A is a protein that in humans is encoded by the BLVRA gene. The protein encoded by this gene belongs to the biliverdin reductase family...

D-xylose reductase (EC 1.1.1.307, XylR, XyrA, msXR, dsXR, monospecific xylose reductase, dual specific xylose reductase, NAD(P)H-dependent xylose reductase, xylose...

Aldose reductase inhibitors are a class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Their target, aldose...

This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase. This enzyme is responsible for...

GMP reductase EC 1.7.1.7 (Guanosine 5'-monophosphate oxidoreductase ) is an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination...

Carbonyl reductase 1, also known as CBR1, is an enzyme which in humans is encoded by the CBR1 gene. The protein encoded by this gene belongs to the short-chain...

systems, e.g., NADH methemoglobin reductase (cytochrome-b5 reductase) (major pathway), NADPH methemoglobin reductase (minor pathway) and to a lesser extent...

2-oxopantoate reductase, 2-ketopantoate reductase, 2-ketopantoic acid reductase, ketopantoate reductase, and ketopantoic acid reductase. This enzyme participates...

semidehydroascorbate reductase, AFR, AFR-reductase, ascorbic free radical reductase, ascorbate free radical reductase, SOR, MDAsA reductase (NADPH), SDA reductase, NADH:...

Sepiapterin reductase deficiency is an inherited pediatric disorder characterized by movement problems, and most commonly displayed as a pattern of involuntary...

P450 reductase (also known as NADPH:ferrihemoprotein oxidoreductase, NADPH:hemoprotein oxidoreductase, NADPH:P450 oxidoreductase, P450 reductase, POR...

Trimethylamine N-oxide reductase (TOR or TMAO reductase, EC 1.7.2.3) is a microbial enzyme that can reduce trimethylamine N-oxide (TMAO) into trimethylamine...

Methionine sulfoxide reductase may refer to: Methionine-S-oxide reductase L-methionine (S)-S-oxide reductase Peptide methionine sulfoxide reductase This set index...

membrane-bound proteins which are members of the short-chain dehydrogenase/reductase family. The 3α-hydroxysteroid dehydrogenase activities of these retinol...

Enzyme Commission (EC) numbering system: Dehydrogenase Luciferase DMSO reductase Category:EC 1.1.1 (with NAD+ or NADP+ as acceptor) Alcohol Dehydrogenase...

In enzymology, 2'-hydroxyisoflavone reductase (EC 1.3.1.45) is an enzyme that catalyzes the chemical reaction 2'-hydroxyformononetin + NADPH     H+  ...

In enzymology, 2-oxoadipate reductase (EC 1.1.1.172) is an enzyme that catalyzes the chemical reaction (R)-2-hydroxyadipic acid + NAD+       H+   H+  ...

In enzymology, a sarcosine reductase (EC 1.21.4.3) is an enzyme that catalyzes the chemical reaction acetyl phosphate + methylamine + thioredoxin disulfide...

use include beta-glutamylphosphate reductase, gamma-glutamyl phosphate reductase, beta-glutamylphosphate reductase, glutamate semialdehyde dehydrogenase...

A dihydrofolate reductase inhibitor (DHFR inhibitor) is a molecule that inhibits the function of dihydrofolate reductase, and is a type of antifolate....

Ferredoxin-thioredoxin reductase EC 1.8.7.2, systematic name ferredoxin:thioredoxin disulfide oxidoreductase, is a [4Fe-4S] protein that plays an important...

In enzymology, a sulfur oxygenase/reductase (EC 1.13.11.55) is an enzyme that catalyzes the chemical reaction 4 sulfur + 4 H2O + O2 ⇌ {\displaystyle \rightleftharpoons...

Dicarbonyl/L-xylulose reductase, also known as carbonyl reductase II, is an enzyme that in human is encoded by the DCXR gene located on chromosome 17...

Ribonucleotide reductase inhibitors are a family of anti-cancer drugs that interfere with the growth of tumor cells by blocking the formation of deoxyribonucleotides...

enzymes, including nitrate reductase (NAR), nitrite reductase (NIR), nitric oxide reductase (NOR) and nitrous oxide reductase (NOS), turning nitrogen oxides...

classified into several groups: CPR-P450 systems combine a cytochrome P450 reductase (CPR) and a P450 domain. Microsomal P450 systems in which electrons are...

malformation syndrome caused by a mutation in the enzyme 7-Dehydrocholesterol reductase encoded by the DHCR7 gene. It causes a broad spectrum of effects, ranging...

In enzymology, a protein-disulfide reductase (EC 1.8.1.8) is an enzyme that catalyzes the chemical reaction protein dithiol + NAD(P)+ ⇌ {\displaystyle...

Putidaredoxin—NAD+ reductase (EC 1.18.1.5, putidaredoxin reductase, camA (gene)) is an enzyme with systematic name putidaredoxin:NAD+ oxidoreductase....

NADH:ubiquinone reductase (non-electrogenic) (EC 1.6.5.9, NDH-2, ubiquinone reductase, coenzyme Q reductase, dihydronicotinamide adenine dinucleotide-coenzyme...

Nitrate reductase (NADH) (EC 1.7.1.1, assimilatory nitrate reductase, NADH-nitrate reductase, NADH-dependent nitrate reductase, assimilatory NADH: nitrate...

2,4 Dienoyl-CoA reductase also known as DECR1 is an enzyme which in humans is encoded by the DECR1 gene which resides on chromosome 8. This enzyme catalyzes...

12-oxophytodienoate reductase (OPRs) is an enzyme of the family of Old Yellow Enzymes (OYE). OPRs are grouped into two groups: OPRI and OPRII – the second...

In enzymology, a peptide-methionine (R)-S-oxide reductase (EC 1.8.4.12) is an enzyme that catalyzes the chemical reaction peptide-L-methionine + thioredoxin...

5'-phosphate reductase (EC 1.1.1.302, 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase, MjaRED, MJ0671 (gene)) is an...

Ribonucleoside-triphosphate reductase (EC 1.17.4.2, ribonucleotide reductase, 2'-deoxyribonucleoside-triphosphate:oxidized-thioredoxin 2'-oxidoreductase)...

Dihydrokaempferol 4-reductase (EC 1.1.1.219) is an enzyme that catalyzes the chemical reaction aromadendrin + NADPH     H+         leucopelargonidin +...

In enzymology, a nitrous oxide reductase also known as nitrogen:acceptor oxidoreductase (N2O-forming) is an enzyme that catalyzes the final step in bacterial...

In enzymology, a cortisone alpha-reductase (EC 1.3.1.4) is an enzyme that catalyzes the chemical reaction 4,5alpha-dihydrocortisone + NADP+ ⇌ {\displaystyle...

Aldo-keto reductase family 1 member B10 is an enzyme that in humans is encoded by the AKR1B10 gene. This gene encodes a member of the aldo/keto reductase superfamily...

Vitamin K epoxide reductase (VKOR) is an enzyme (EC 1.17.4.4) that reduces vitamin K after it has been oxidised in the carboxylation of glutamic acid...

Assimilatory nitrate reductase may refer to: Nitrate reductase (NADH) Nitrate reductase (NAD(P)H) Nitrate reductase (NADPH) Nitrite reductase This disambiguation...

nitrate reductase and of pig NADH:cytochrome b5 reductase have been solved. The overall fold is similar to that of ferredoxin:NADP+ reductase: the FAD-binding...

NADH-CoQ reductase may be: NADH dehydrogenase, an enzyme NADH:ubiquinone reductase (non-electrogenic), an enzyme This set index page lists enzyme articles...

In enzymology, a 5,10-methylenetetrahydromethanopterin reductase (EC 1.5.98.2) is an enzyme that catalyzes the chemical reaction 5-methyltetrahydromethanopterin...

Betaine reductase (EC 1.21.4.4) is an enzyme that catalyzes the chemical reaction acetyl phosphate + trimethylamine + thioredoxin disulfide ⇌ {\displaystyle...

dehydrogenase. Now EC 1.1.1.303, diacetyl reductase [(R)-acetoin forming] and EC 1.1.1.304, diacetyl reductase [(S)-acetoin forming] EC 1.1.1.6: glycerol...

In molecular biology, the glucose-methanol-choline oxidoreductase family (GMC oxidoreductase) is a family of enzymes with oxidoreductase activity. The...

In enzymology, a progesterone 5alpha-reductase (EC 1.3.1.22) is an enzyme that catalyzes the chemical reaction 5alpha-pregnan-3,20-dione + NADP+ ⇌ {\displaystyle...

In enzymology, a tropinone reductase I (EC 1.1.1.206) is an enzyme that catalyzes the chemical reaction tropine + NADP+ ⇌ {\displaystyle \rightleftharpoons...

NADH-coenzyme Q reductase may refer to the following enzymes: NADH dehydrogenase NADH:ubiquinone reductase (non-electrogenic) This set index page lists...

ferredoxin-NADP+ reductases, plant and fungal NAD(P)H:nitrate reductases, cytochrome b5 reductases, cytochrome P450 reductases, sulphite reductases, nitric oxide...

In enzymology, a leghemoglobin reductase (EC 1.6.2.6) is an enzyme that catalyzes the chemical reaction NAD(P)H + H+ + 2 ferrileghemoglobin ⇌ {\displaystyle...

NADH-ubiquinone reductase may refer to the following enzymes: NADH dehydrogenase NADH:ubiquinone reductase (non-electrogenic) This set index page lists...

the second reaction, biliverdin is converted to bilirubin by biliverdin reductase (BVR): Bilirubin is transported into the liver by facilitated diffusion...

FMN reductase (NADH) (EC 1.5.1.42, NADH-FMN reductase) is an enzyme with systematic name FMNH2:NAD+ oxidoreductase. This enzyme catalyses the following...

Aldo-keto reductase family 1 member C1 also known as 20α-hydroxysteroid dehydrogenase, 3α-hydroxysteroid dehydrogenase, and dihydrodiol dehydrogenase...

NADH-cytochrome b5 reductase 3 is an enzyme that in humans is encoded by the CYB5R3 gene. The CYB5R3 gene is located on the 22nd chromosome, with its...

The nitrate reductase test is a test to differentiate between bacteria based on their ability or inability to reduce nitrate (NO3−) to nitrite (NO2−)...

In enzymology, hydroxymethylglutaryl-CoA reductase (EC 1.1.1.88) is an enzyme that catalyzes the chemical reaction Mevalonic acid + Coenzyme A + 2 NAD+...

Azobenzene reductase also known as azoreductase (EC 1.7.1.6) is an enzyme that catalyzes the chemical reaction: 4-(dimethylamino)azobenzene + 2 NADPH...

This article is about the discovery and development of 5α-reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers. These are two...

citrinum by Akira Endo in the 1970s, and he identified it as a HMG-CoA reductase inhibitor, i.e., a statin. Mevastatin might be considered the first statin...

In enzymology, pyrroline-5-carboxylate reductase (EC 1.5.1.2) is an enzyme that catalyzes the chemical reaction (S)-1-pyrroline-5-carboxylic acid + NADH...

In molecular biology, the HMG-CoA reductase family is a family of enzymes which participate in the mevalonate pathway, the metabolic pathway that produces...

Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is an enzyme that in humans is encoded by the RRM2...

Cystine reductase (EC 1.8.1.6) is an enzyme that catalyzes the chemical reaction cystine + NADPH     H+   H+     2   cysteine + NAD+   The three substrates...

In enzymology, an acetoacetyl-CoA reductase (EC 1.1.1.36) is an enzyme that catalyzes the chemical reaction (R)-3-hydroxyacyl-CoA + NADP+       H+   H+...

15-oxo-Delta13-prostaglandin reductase, Delta13-15-ketoprostaglandin reductase, 15-ketoprostaglandin Delta13-reductase, prostaglandin Delta13-reductase, prostaglandin...

(−)-Isopiperitenone reductase (EC 1.3.1.82) is an enzyme with systematic name (+)-cis-isopulegone:NADP+ oxidoreductase that is found in peppermint. It...

In enzymology, a rubredoxin—NAD(P)+ reductase (EC 1.18.1.4) is an enzyme that catalyzes the chemical reaction reduced rubredoxin + NAD(P)+ ⇌ {\displaystyle...

In enzymology, a ferredoxin—nitrate reductase (EC 1.7.7.2) is an enzyme that catalyzes the chemical reaction nitrite + H2O + 2 oxidized ferredoxin ⇌ {\displaystyle...

by the Nif genes or homologs. They are related to protochlorophyllide reductase. Although the equilibrium formation of ammonia from molecular hydrogen...

In enzymology, enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) (EC 1.3.1.10) is an enzyme that catalyzes the chemical reaction The enzyme converts...

In enzymology, a NADPH—hemoprotein reductase is an enzyme that catalyzes the chemical reaction NADPH + H+ + n oxidized hemoprotein ⇌ {\displaystyle \rightleftharpoons...

not humans. It works by blocking folate metabolism via dihydrofolate reductase in some bacteria, preventing creation of bacterial DNA and RNA and leading...

6,7-dihydropteridine reductase (EC 1.5.1.34, also dihydrobiopterin reductase) is an enzyme that catalyzes the chemical reaction dihydrobiopterin + 2 NADH...

week follow-up. Mexazolam is metabolised via the CYP3A4 pathway. HMG-CoA reductase inhibitors including simvastatin, simvastatin acid, lovastatin, fluvastatin...

In enzymology, cholestenone 5alpha-reductase (EC 1.3.1.22) is an enzyme that catalyzes several chemical reactions of steroids in which a cholest-4-en-3-one...

Ribonucleotide-diphosphate reductase subunit M2 B is an enzyme that in humans is encoded by the RRM2B gene. The gene encoding the RRM2B protein is located...

Diacetyl reductase ((R)-acetoin forming) (EC 1.1.1.303, (R)-acetoin dehydrogenase) is an enzyme with systematic name (R)-acetoin:NAD+ oxidoreductase....

In enzymology, a CoB—CoM heterodisulfide reductase (EC 1.8.98.1) is an enzyme that catalyzes the chemical reaction coenzyme B + coenzyme M + methanophenazine...

Aldo-keto reductase family 1, member B1 (AKR1B1) is an gene in humans that encodes the enzyme aldose reductase. It is a reduced nicotinamide-adenine dinucleotide...

3-dehydrosphinganine reductase (EC 1.1.1.102) also known as 3-ketodihydrosphingosine reductase (KDSR) or follicular variant translocation protein 1 (FVT1)...

3 ACPs, and a thioesterase (TE) domain. It does not contain an enoyl reductase (ER) domain, which would be required for the complete reduction to the...

ADP-ribosyl-[dinitrogen reductase] hydrolase (EC 3.2.2.24) is an enzyme that catalyzes the chemical reaction ADP-D-ribosyl-[dinitrogen reductase] ⇌ {\displaystyle...

Nitric oxide reductase (NAD(P), nitrous oxide-forming) (EC 1.7.1.14, fungal nitric oxide reductase, cytochrome P450nor, NOR (ambiguous)) is an enzyme...

Superoxide reductase is an enzyme that catalyzes the conversion of highly reactive and toxic superoxide (O2−) into less toxic hydrogen peroxide (H2O2):...

In enzymology, anthocyanidin reductase (EC 1.3.1.77) is an enzyme that catalyzes the general chemical reaction an anthocyanidin + 2 NAD(P)H + H+ ⇌ {\displaystyle...

DPNH-coenzyme Q reductase may refer to the following enzymes: NADH dehydrogenase NADH:ubiquinone reductase (non-electrogenic) This set index page lists...

Sulfonucleotide reductases are a class of enzymes involved in reductive sulfur assimilation. This reaction consists of a conversion from activated sulfate...

In enzymology, 2,5-didehydrogluconate reductase (EC 1.1.1.274) is an enzyme that catalyzes the chemical reaction 2-dehydro-D-gluconic acid + NADP+    ...

Crotonyl-CoA carboxylase/reductase (EC 1.3.1.85, CCR, crotonyl-CoA reductase (carboxylating)) is an enzyme with systematic name (2S)-ethylmalonyl-CoA:NADP+...

In enzymology, a mevaldate reductase (NADPH) (EC 1.1.1.33) is an enzyme that catalyzes the chemical reaction (R)-mevalonate + NADP+ ⇌ {\displaystyle \rightleftharpoons...

NAD+-dinitrogen-reductase ADP-D-ribosyltransferase (EC 2.4.2.37) is an enzyme that catalyzes the chemical reaction NAD+ + [dinitrogen reductase] ⇌ {\displaystyle...

4-(dimethylamino)phenylazoxybenzene reductase (EC 1.7.1.11) is an enzyme that catalyzes the chemical reaction 4-(dimethylamino)phenylazoxybenzene + NADPH...

Pteridine reductase (EC 1.5.1.33) is an enzyme that catalyzes the chemical reaction biopterin + 2 NADPH     2 H+   2 H+     tetrahydrobiopterin + 2 NADP+...

Adrenodoxin-NADP+ reductase (EC 1.18.1.6, adrenodoxin reductase, nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase, ADR, NADPH:adrenal...

In enzymology, a selenate reductase (EC 1.97.1.9) is an enzyme that catalyzes the chemical reaction selenite + H2O + acceptor ⇌ {\displaystyle \rightleftharpoons...

the fetus. Like all statins, pravastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver that plays a role in producing cholesterol....

In enzymology, 2-dehydropantolactone reductase (A-specific) (EC 1.1.1.168) is an enzyme that catalyzes the chemical reaction (R)-pantolactone + NADP+...

coenzyme-B sulfoethylthiotransferase, also known as methyl-coenzyme M reductase (MCR) or most systematically as 2-(methylthio)ethanesulfonate:N-(7-th...

In enzymology, a trans-2-enoyl-CoA reductase (NADPH) (EC 1.3.1.38) is an enzyme that catalyzes the chemical reaction trans-2,3-dehydroacyl-CoA + NADPH...

reductase. Since tetrahydrofolate is needed to make both purines and pyrimidines, which are building blocks of DNA and RNA, dihydrofolate reductase is...

[Methionine synthase] reductase, or Methionine synthase reductase, encoded by the gene MTRR, is an enzyme that is responsible for the reduction of methionine...

In enzymology, Delta14-sterol reductase (EC 1.3.1.70) is an enzyme that catalyzes the chemical reaction 14-demethyllanosterol + NADP+       H+   H+  ...

2,4 Dienoyl-CoA reductase deficiency is an inborn error of metabolism resulting in defective fatty acid oxidation caused by a deficiency of the enzyme...

Polyprenol reductase (EC 1.3.1.94, SRD5A3 (gene), DFG10 (gene)) is an enzyme with systematic name ditrans,polycis-dolichol:NADP+ 2,3-oxidoreductase. This...

domain, ferredoxin or cytochrome b5 transfer electrons between the flavin reductase (protein or domain) and P450. While P450-containing systems are found...

local conversion via 5α-reductase into DHT in tissues where 5α-reductase is expressed, an AAS that is not metabolized by 5α-reductase or is already 5α-reduced...

In enzymology, Delta24(241)-sterol reductase (EC 1.3.1.71) is an enzyme that catalyzes the chemical reaction ergosta-5,7,22,24(28)-tetraen-3β-ol + NADPH...

deiodinases, thioredoxin reductases, formate dehydrogenases, glycine reductases, selenophosphate synthetase 2, methionine-R-sulfoxide reductase B1 (SEPX1), and...

metabolite of nandrolone and is formed from it by the actions of the enzyme 5α-reductase analogously to the formation of dihydrotestosterone (DHT) from testosterone...

Methylecgonone reductase (EC 1.1.1.334, MecgoR (gene name)) is an enzyme with systematic name ecgonine methyl ester:NADP+ oxidoreductase. This enzyme...

In enzymology, a NADPH:quinone reductase (EC 1.6.5.5) is an enzyme that catalyzes the chemical reaction NADPH + H+ + 2quinone ⇌ {\displaystyle \rightleftharpoons...

dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase...

cholesterol) stop the production of mevalonate by inhibiting HMG-CoA reductase. Mevalonic acid is very soluble in water and polar organic solvents. It...

Perakine reductase (EC 1.1.1.317) is an enzyme with systematic name raucaffrinoline:NADP+ oxidoreductase. This enzyme catalyses the following chemical...

oxidoreductase. Other names in common use include menadione reductase, phylloquinone reductase, quinone reductase, dehydrogenase, reduced nicotinamide adenine dinucleotide...

In enzymology, 6-hydroxynicotinate reductase (EC 1.3.7.1) is an enzyme that catalyzes the chemical reaction 6-hydroxynicotinic acid + reduced ferredoxin...

In enzymology, fumarate reductase (NADH) (EC 1.3.1.6) is an enzyme that catalyzes the chemical reaction fumaric acid + NADH     H+   H+     succinic acid...

areata – immunomodulator Dutasteride (AD-208) – oral – alopecia – 5α-reductase inhibitor Minoxidil oral extended-release (VDPHL01, VDPHL-01, VDPHL) –...

In enzymology, a tropinone reductase II (EC 1.1.1.236) is an enzyme that catalyzes the chemical reaction pseudotropine + NADP+ ⇌ {\displaystyle \rightleftharpoons...

in common use include D-glycerate dehydrogenase, and hydroxypyruvate reductase (due to the reversibility of the reaction). This enzyme participates in...

In enzymology, tetrahydroxynaphthalene reductase (EC 1.1.1.252) is an enzyme that catalyzes the chemical reaction scytalone + NADP+       H+   H+   naphthalene-1...

The short-chain dehydrogenases/reductases family (SDR) is a very large family of enzymes, most of which are known to be NAD- or NADP-dependent oxidoreductases...

Dihydrofolate reductase deficiency (DHFR deficiency) is an ultra-rare condition with less than 20 reported cases within the literature, as of 2025. It...

two amine groups on a pyrimidine ring. They include many dihydrofolate reductase inhibitor drugs (such as pyrimethamine, trimetrexate, and piritrexim and...

The discovery of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia...

Adenylyl-sulfate reductase (thioredoxin) (EC 1.8.4.10) is an enzyme that catalyzes the chemical reaction AMP + sulfite + thioredoxin disulfide ⇌ {\displaystyle...

In enzymology, sorbose reductase (EC 1.1.1.289) is an enzyme that catalyzes the chemical reaction D-sorbitol + NADP+       H+   H+   L-sorbose + NADPH...

preposition Por, a Portuguese preposition POR (gene), cytochrome P450 reductase Portugal, IOC country code Power-on reset Program of Record (PoR), a term...

Peptide methionine sulfoxide reductase may refer to: Protein-methionine-S-oxide reductase Peptide-methionine (S)-S-oxide reductase This set index page lists...

In enzymology, a glucuronate reductase (EC 1.1.1.19) is an enzyme that catalyzes the chemical reaction L-gulonic acid + NADP+       H+   H+   D-glucoronic...

restored to the required cofactor tetrahydrobiopterin by dihydrobiopterin reductase. Dihydrobiopterin is an intermediate in the pathway to the cofactor, tetrahydrobiopterin...

symptoms, medications may include alpha blockers such as terazosin or 5α-reductase inhibitors such as finasteride. Surgical removal of part of the prostate...

dihydrofolate reductase, an enzyme that is potently inhibited by methotrexate. Methotrexate blocks the action of dihydrofolate reductase and thereby halts...

In enzymology, a methylarsonate reductase (EC 1.20.4.2) is an enzyme that catalyzes the chemical reaction methylarsonate + 2 glutathione ⇌ {\displaystyle...

mycothione reductase. Mycothiol biosynthesis and mycothiol-dependent enzymes such as mycothiol-dependent formaldehyde dehydrogenase and mycothione reductase have...

In enzymology, maleylacetate reductase (EC 1.3.1.32) is an enzyme that catalyzes the chemical reaction 3-oxoadipic acid + NAD+       H+   H+   maleylacetic...

Methionine-S-oxide reductase (EC 1.8.4.5, methyl sulfoxide reductase I and II, acetylmethionine sulfoxide reductase, methionine sulfoxide reductase,...

Succinate dehydrogenase (SDH) or succinate-coenzyme Q reductase (SQR) or respiratory complex II is an enzyme complex, found in many bacterial cells and...

and fungi. The majority of antifolates work by inhibiting dihydrofolate reductase (DHFR). Methotrexate Pemetrexed Raltitrexed Pralatrexate Many are primarily...

nicotinamide adenine dinucleotide-coenzyme Q reductase may stand for NADH dehydrogenase NADH:ubiquinone reductase (non-electrogenic) This disambiguation page...

Carvone reductase (EC 1.3.99.25) is an enzyme with systematic name (+)-dihydrocarvone:acceptor 1,6-oxidoreductase. This enzyme catalyses the following...

Aflatoxin B1 aldehyde reductase member 2 is an enzyme that in humans is encoded by the AKR7A2 gene. Aldo-keto reductases, such as AKR7A2, are involved...

diphosphate reductase (EC 1.17.1.2, isopentenyl-diphosphate:NADP+ oxidoreductase, LytB, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, HMBPP reductase...

7-Hydroxymethyl chlorophyll a reductase (EC 1.17.7.2, HCAR) is an enzyme with systematic name 71-hydroxychlorophyll a:ferredoxin oxidoreductase. This...

Geranylgeranyl diphosphate reductase (EC 1.3.1.83, geranylgeranyl reductase, CHL P) is an enzyme with systematic name geranylgeranyl-diphosphate:NADP+...

In enzymology, erythrulose reductase (EC 1.1.1.162) is an enzyme that catalyzes the chemical reaction D-threitol + NADP+       H+   H+   D-erythrulose...

In enzymology, a D-xylulose reductase (EC 1.1.1.9) is an enzyme that is classified as an Oxidoreductase (EC 1) specifically acting on the CH-OH group...

Mitochondrial enoyl reductase protein-associated neurodegeneration (MePAN, MEPAN), also known as MEPAN syndrome, is a rare genetic mitochondrial metabolic...

FMN reductase (NADPH) (EC 1.5.1.38, FRP, flavin reductase P, SsuE) is an enzyme with systematic name FMNH2:NADP+ oxidoreductase. This enzyme catalyses...

Aldo-keto reductase family 1 member C3 (AKR1C3), also known as 17β-hydroxysteroid dehydrogenase type 5 (17β-HSD5, HSD17B5) or 3α-hydroxysteroid dehydrogenase...

Nitrate reductase (quinone) (EC 1.7.5.1, nitrate reductase A, nitrate reductase Z, quinol/nitrate oxidoreductase, quinol-nitrate oxidoreductase, quinol:nitrate...

attached (dFdCDP) also has activity; it inhibits the enzyme ribonucleotide reductase (RNR), which is needed to create new DNA nucleotides. The lack of nucleotides...

the fetus. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol...

In enzymology, cucurbitacin Delta23-reductase (EC 1.3.1.5) is an enzyme that catalyzes the chemical reaction cucurbitacin b + NADH     H+   H+     dihydrocucurbitacin...

flavohemoprotein, mammalian NADH-cytochrome b5 reductase, eukaryotic NADPH-cytochrome P450 reductase, nitrate reductase from plants, nitric-oxide synthase, bacterial...

dephospho-[reductase kinase] kinase (EC 2.7.11.3) is an enzyme that catalyzes the chemical reaction ATP + dephospho-{[hydroxymethylglutaryl-CoA reductase (NADPH)]...

4,7β-dimethyl-4-aza-5α-cholestan-3-one, is a synthetic, steroidal 5α-reductase inhibitor which was first reported in 1994 and was never marketed. It...

In enzymology, a CoA-disulfide reductase (EC 1.8.1.14) is an enzyme that catalyzes the chemical reaction 2 CoA + NAD(P)+ ⇌ {\displaystyle \rightleftharpoons...

4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) is an enzyme that catalyzes the chemical reaction (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic...

In enzymology, an enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) (EC 1.3.1.39) is an enzyme that catalyzes the chemical reaction acyl-[acyl-carrier-protein]...

Cytochrome b5 reductase 4 is an enzyme that in humans is encoded by the CYB5R4 gene. NCB5OR is a flavohemoprotein that contains functional domains found...

Peptide methionine sulfoxide reductase (Msr) is a family of enzymes that in humans is encoded by the MSRA gene. Msr is ubiquitous and highly conserved...

(S)-S-oxide reductase (EC 1.8.4.11, MsrA, methionine sulphoxide reductase A, methionine S-oxide reductase (S-form oxidizing), methionine sulfoxide reductase A,...

In enzymology, a chlordecone reductase (EC 1.1.1.225) is an enzyme that catalyzes the chemical reaction chlordecone alcohol + NADP+ ⇌ {\displaystyle \rightleftharpoons...

Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330, very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, KCR (gene), IFA38 (gene))...

lysosomal thiol reductase is an enzyme that, in humans, is encoded by the IFI30 gene. The protein encoded by this gene is a lysosomal thiol reductase that at...

Topical corticosteroids (e.g., hydrocortisone) Alopecia treatments 5α-Reductase inhibitors Alfatradiol Dutasteride Finasteride Saw palmetto extract Antiandrogens...

In enzymology, a trans-2-enoyl-CoA reductase (NAD+) (EC 1.3.1.44) is an enzyme that catalyzes the chemical reaction trans-2,3-dehydroacyl-CoA + NADH +...

QDPR (quinoid dihydropteridine reductase) is a human gene that produces the enzyme quinoid dihydropteridine reductase. This enzyme is part of the pathway...

In enzymology, hydroxypyruvate reductase (EC 1.1.1.81) is an enzyme that catalyzes the chemical reaction D-glyceric acid + NAD+       H+   H+   hydroxypyruvic...

In enzymology, a rubredoxin-NAD+ reductase (EC 1.18.1.1) is an enzyme that catalyzes the chemical reaction. 2 reduced rubredoxin + NAD+ + H+ ⇌ {\displaystyle...

The red chlorophyll catabolite reductase (RCC reductase) family of proteins consists of several reductase enzymes. They act together with pheophorbide...

Cinnamoyl-CoA reductase (EC 1.2.1.44), systematically named cinnamaldehyde:NADP+ oxidoreductase (CoA-cinnamoylating) but commonly referred to by the acronym...

In enzymology, 4-oxoproline reductase (EC 1.1.1.104) is an enzyme that catalyzes the chemical reaction cis-4-hydroxyproline + NAD+       H+   H+   4-oxo-L-proline...

AMPK also phosphorylates and inactivates 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), a key enzyme in cholesterol synthesis. HMGR converts...

names in common use include FAD-dependent malate-vitamin K reductase, malate-vitamin K reductase, and (S)-malate:(quinone) oxidoreductase. This enzyme participates...

parasitic worm Ascaris suum, an enzyme similar to complex II, fumarate reductase (menaquinol:fumarate oxidoreductase, or QFR), operates in reverse to oxidize...

FAD reductase (NADH) (EC 1.5.1.37, NADH-FAD reductase, NADH-dependent FAD reductase) is an enzyme with systematic name FADH2:NAD+ oxidoreductase. This...

form of folic acid that does not require activation by dihydrofolate reductase to be useful to the body. Folinic acid was first made in 1945. In 2025...

Trypanothione-disulfide reductase (EC 1.8.1.12) is an enzyme that catalyzes the chemical reaction trypanothione disulfide + NADPH     H+   H+     trypanothione...

NADH:ubiquinone oxidoreductase (complex I), Coenzyme Q – cytochrome c reductase (complex III), and cytochrome c oxidase (complex IV). Complex I is the...

In enzymology, phloroglucinol reductase (EC 1.3.1.57) is an enzyme that catalyzes the chemical reaction (1) + NADP+       H+   H+   (2) + NADPH   The...

Asparagusate reductase (EC 1.8.1.11) is an enzyme that catalyzes the chemical reaction asparagusic acid + NADPH     H+   H+     3-mercapto-2-mercaptomethylpropanoic...

Dimethyl sulfide:cytochrome c2 reductase (EC 1.8.2.4) is an enzyme with systematic name dimethyl sulfide:cytochrome-c2 oxidoreductase. It is also known...

In enzymology, 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) (EC 1.1.1.292) is an enzyme that catalyzes the chemical reaction 1,5-anhydro-D-mannitol...

least four different pathways for the catabolism of D-xylose: An oxido-reductase pathway is present in eukaryotic microorganisms. Prokaryotes typically...

CoB–S–S–CoM This conversion is catalyzed by the enzyme methyl coenzyme M reductase, which contains cofactor F430 as the prosthetic group. A related conversion...

antimicrobial Penicillium frequentans isolate. Sclerotiorin is an aldose reductase inhibitor (IC50=0.4 μM) as well as a reversible lipoxygenase inhibitor...

abnormally dark bluish brown. The NADH-dependent enzyme methemoglobin reductase (a type of diaphorase) is responsible for converting methemoglobin back...

Glutathione amide reductase (EC 1.8.1.16, GAR) is an enzyme with systematic name glutathione amide:NAD+ oxidoreductase. This enzyme catalyses the following...

In enzymology, a diiodophenylpyruvate reductase (EC 1.1.1.96) is an enzyme that catalyzes the chemical reaction 3-(3,5-diiodo-4-hydroxyphenyl)lactate...

methenyltetrahydrofolate. It is substrate for the enzyme methylenetetrahydrofolate reductase (MTHFR), which gives 5-methyltetrahydrofolate. It is mainly produced by...

3-hydroxy-3-methylglutaryl (HMG) coenzyme A reductase. HMG-CoA reductase, the rate-limiting enzyme of the HMG-CoA reductase pathway, the metabolic pathway responsible...

Carbonyl reductase [NADPH] 3 is an enzyme that in humans is encoded by the CBR3 gene. The enzyme is a member of short chain dehydrogenase/reductase superfamily...

encoded by the RDH11 gene. RHD11, a member of the short-chain dehydrogenase/reductase (SDR) superfamily of oxidoreductases, is expressed at high levels in prostate...

Riboflavin reductase (NAD(P)H) (EC 1.5.1.41, NAD(P)H-FMN reductase, Fre) is an enzyme with systematic name riboflavin:NAD(P)+ oxidoreductase. This enzyme...

Polysulfide reductase (NrfD) is an integral transmembrane protein with loops in both the periplasm and the cytoplasm. NrfD is thought to participate in...

NAD+-linked formaldehyde dehydrogenase, s-nitrosoglutathione reductase (GSNO reductase) and NAD+-dependent formaldehyde dehydrogenase. This enzyme participates...

enzymes in the methionine sulfoxide reductase family of enzymes. The three known methionine sulfoxide reductases are MsrA, MsrB, and fRmsr. Oxidation...

the baby. Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol...

In enzymology, a cyanocobalamin reductase (cyanide-eliminating) (EC 1.16.1.6) is an enzyme that catalyzes the chemical reaction cob(I)alamin + cyanide...

Nitric oxide reductase (menaquinol) (EC 1.7.5.2) is an enzyme. This enzyme catalyses the following chemical reaction 2 nitric oxide + menaquinol ⇌ {\displaystyle...

Arsenate reductase (glutaredoxin) (EC 1.20.4.1) is an enzyme that catalyzes the chemical reaction arsenate + glutaredoxin ⇌ {\displaystyle \rightleftharpoons...

In enzymology, a protein-disulfide reductase (glutathione) (EC 1.8.4.2) is an enzyme that catalyzes the chemical reaction 2 glutathione + protein-disulfide...

In enzymology, a hydroxylamine reductase (EC 1.7.99.1) is an enzyme that catalyzes the chemical reaction NH3 + H2O + acceptor ⇌ {\displaystyle \rightleftharpoons...

In enzymology, a hydroxyphenylpyruvate reductase (EC 1.1.1.237) is an enzyme that catalyzes the chemical reaction 3-(4-hydroxyphenyl)lactate + NAD+ ⇌...

Flavin reductase (NADH) (EC 1.5.1.36, NADH-dependent flavin reductase, flavin:NADH oxidoreductase) is an enzyme with systematic name flavin:NAD+ oxidoreductase...

group of the mitochondrial P450. The structures of the reductase of the microsomal versus reductase of the mitochondrial P450 systems are completely different...

In enzymology, acylglycerone-phosphate reductase (EC 1.1.1.101) is an enzyme that catalyzes the chemical reaction 1-palmitoylglycerol 3-phosphate R=CH3(CH2)14...

higher 5α-reductase, higher total testosterone, higher unbound/free testosterone, and higher free androgens, including DHT. 5-alpha-reductase converts...

reductase making it unavailable for HMG-CoA. Cerivastatin is a pure synthetic drug, produced to create a more potent inhibitor of HMG-CoA reductase....

mesenchymal cells and associated with prune belly syndrome. Observed in 5α-reductase 2 deficiency in which impaired 5α-dihydrotestosterone (DHT) synthesis...

In enzymology, a L-methionine (S)-S-oxide reductase (EC 1.8.4.13) is an enzyme that catalyzes the chemical reaction L-methionine + thioredoxin disulfide...

They are biosynthesized by plants, animals and fungi via the HMG-CoA reductase pathway, with geranylgeranyl pyrophosphate being a primary intermediate...

Glyoxylate reductase/hydroxypyruvate reductase is an enzyme that in humans is encoded by the GRHPR gene. This gene encodes an enzyme with hydroxypyruvate...

A glutamyl-tRNA reductase (EC 1.2.1.70) is an enzyme that catalyzes the chemical reaction L-glutamate 1-semialdehyde + NADP+ + tRNAGlu ⇌ {\displaystyle...

a NDP, then is converted to a dNDP by an enzyme called ribonucleotide reductase, then a phosphate is added back to give a dNTP. A nitrogenous base called...

ribonucleotide reductase. Moreover, GRX act in antioxidant defense by reducing dehydroascorbate, peroxiredoxins, and methionine sulfoxide reductase. Beside their...

In enzymology, 2-hexadecenal reductase (EC 1.3.1.27) is an enzyme that catalyzes the chemical reaction 2-trans-hexadecanal + NADPH     H+   H+     hexadecanal...

and sulfuretin are antioxidants, and have inhibitory effects on aldose reductase and advanced glycation processes. Buddhist monks who practiced Sokushinbutsu...

In enzymology, a 2-oxo-acid reductase (EC 1.1.99.30) is an enzyme that catalyzes the chemical reaction a (2R)-hydroxy-carboxylate + acceptor ⇌ {\displaystyle...

In enzymology, a carboxylate reductase (EC 1.2.99.6) is an enzyme that catalyzes the chemical reaction an aldehyde + acceptor + H2O ⇌ {\displaystyle \rightleftharpoons...

ERG4 or Delta(24(24(1)))-sterol reductase or Delta(24(28))-sterol reductase is an enzyme that catalyzes the last step of ergosterol biosynthesis pathway...

Thioredoxin reductase 1, cytoplasmic is an enzyme that in humans is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide...

Tagaturonate reductase (EC 1.1.1.58) is an enzyme that catalyzes the chemical reaction D-Altronic acid + NAD+       H+   H+   D-Tagaturonic acid + NADH...

In enzymology, a diferric-transferrin reductase (EC 1.16.1.2) is an enzyme that catalyzes the chemical reaction transferrin[Fe(II)]2 + NAD+ + H+ ⇌ {\displaystyle...

inhibitors can be further divided mostly into CYP17A1 inhibitors and 5α-reductase inhibitors; and antigonadotropins can be further divided into gonadotropin-releasing...

In enzymology, a lactaldehyde reductase (NADPH) (EC 1.1.1.55) is an enzyme that catalyzes the chemical reaction Propylene glycol + NADP+       H+   H+...

genital tubercle is sensitive to dihydrotestosterone and rich in 5-alpha-reductase, so that the amount of fetal testosterone present after the second month...

bacteria and archaea. Sulfur oxidizers use enzymes such as Sulfide:quinone reductase, sulfur dioxygenase and sulfite oxidase to oxidize sulfur compounds to...

macrocycle to give siroheme. Ferredoxin-nitrite reductase Hydrogensulfite reductase Nitrite reductase (NAD(P)H) Matthew J. Murphy; et al. (1974). "Siroheme:...

In enzymology, indole-3-acetaldehyde reductase (NADPH) (EC 1.1.1.191) is an enzyme that catalyzes the chemical reaction tryptophol + NADP+       H+  ...

similarly. Benzoyl-CoA is a substrate for diverse reductases: 4-hydroxybenzoyl-CoA reductase, benzoyl-CoA reductase, benzoyl-CoA 3-monooxygenase, benzoate-CoA...

liver's ability to produce cholesterol by blocking the enzyme HMG-CoA reductase. Lovastatin was patented in 1979 and approved for medical use in 1987...

sweetvetch or white sweetvetch, is a perennial herb species. Leucocyanidin reductase (LCR) uses 2,3-trans-3,4-cis-leucocyanidin to produce (+)-catechin and...

In enzymology, apiose 1-reductase (EC 1.1.1.114) is an enzyme that catalyzes the chemical reaction D-Apiitol + NAD+       H+   H+   D-Apiose + NADH  ...

In enzymology, a hyponitrite reductase is an enzyme that catalyzes the oxidation of hydroxylamine H 2NOH by the nicotinamide adenine dinucleotide cation...

In enzymology, a hydroxylamine reductase (NADH) (EC 1.7.1.10) is an enzyme that catalyzes the chemical reaction. NH3 + NAD+ + H2O ⇌ {\displaystyle \rightleftharpoons...

In enzymology, a nitroquinoline-N-oxide reductase (EC 1.7.1.9) is an enzyme that catalyzes the chemical reaction 4-(hydroxyamino)quinoline N-oxide + 2...

(proposed tradename Xcytrin) is an inhibitor of thioredoxin reductase and ribonucleotide reductase. It has been proposed as a possible chemotherapeutic agent...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

2− + H2O (Nitrate reductase) NO 2− + 2 H+ + e− → NO + H2O (Nitrite reductase) 2 NO + 2 H+ + 2 e− → N 2O + H2O (Nitric-oxide reductase) N 2O + 2 H+ + 2...

Malonyl CoA reductase (malonate semialdehyde-forming) (EC 1.2.1.75, NADP-dependent malonyl CoA reductase, malonyl CoA reductase (NADP)) is an enzyme with...

Trypanothione-dependent enzymes include reductases, peroxidases, glyoxalases and transferases. Trypanothione-disulfide reductase (TryR) was the first trypanothione-dependent...

2,4-dienoyl-CoA reductase 1 is a protein that in humans is encoded by the DECR1 gene. This gene encodes an accessory enzyme which participates in the...

In enzymology, a CoA-glutathione reductase (EC 1.8.1.10) is an enzyme that catalyzes the chemical reaction CoA + glutathione + NADP+ ⇌ {\displaystyle...

Entner–Doudoroff pathway, but NADPH production remains the same. Ferredoxin–NADP+ reductase, present in all domains of life, is a major source of NADPH in photosynthetic...

Photosystem II (or water-plastoquinone oxidoreductase) is the first protein complex in the light-dependent reactions of oxygenic photosynthesis. It is...

Nitrate reductase (cytochrome) (EC 1.9.6.1, respiratory nitrate reductase, benzyl viologen-nitrate reductase) is an enzyme with systematic name ferrocytochrome:nitrate...

proteins, and 6 low-molecular-weight proteins. Ubiquinol—cytochrome-c reductase catalyzes the chemical reaction QH2 + 2 ferricytochrome c ⇌ {\displaystyle...

(EC 1.10.2.2)—also known as the bc1 complex or ubiquinol-cytochrome c reductase. In plant chloroplasts and cyanobacteria, there is a homologous protein...

Mitochondrial trans-2-enoyl-CoA reductase (MECR) is an enzyme that in humans is encoded by the MECR gene. It belongs to the enzyme class of oxidoreductases...

Ribonucleoside-diphosphate reductase large subunit is an enzyme that in humans is encoded by the RRM1 gene. This gene encodes one of two non-identical...

DXP reductoisomerase (1-deoxy-D-xylulose 5-phosphate reductoisomerase or DXR) is an enzyme that interconverts 1-deoxy-D-xylulose 5-phosphate (DXP) and...

Sulfite reductase (ferredoxin) (EC 1.8.7.1, ferredoxin-sulfite reductase) is an enzyme with systematic name hydrogen-sulfide:ferredoxin oxidoreductase...

Nitrate reductase (NAD(P)H) (EC 1.7.1.2, assimilatory nitrate reductase, assimilatory NAD(P)H-nitrate reductase, NAD(P)H bispecific nitrate reductase, nitrate...

In enzymology, a mevaldate reductase (EC 1.1.1.32) is an enzyme that catalyzes the chemical reaction (R)-mevalonate + NAD+ ⇌ {\displaystyle \rightleftharpoons...

Sulfide:quinone reductase (SQR , EC 1.8.5.4) is an enzyme with systematic name sulfide:quinone oxidoreductase. This enzyme catalyses the following chemical...

In enzymology, a D-proline reductase (dithiol) (EC 1.21.4.1) is an enzyme that catalyzes the chemical reaction 5-aminopentanoate + lipoate ⇌ {\displaystyle...

dehydrogenases or reductases, with NADH-ubiquinone oxidoreductase commonly being called NADH dehydrogenase or sometimes coenzyme Q reductase. There are many...

In enzymology, a mannose-6-phosphate 6-reductase (EC 1.1.1.224) is an enzyme that catalyzes the chemical reaction D-mannitol 1-phosphate + NADP+ ⇌ {\displaystyle...

In enzymology, glyoxylate reductase (NADP+) (EC 1.1.1.79) is an enzyme that catalyzes the chemical reaction glycolic acid + NADP+       H+   H+   glyoxylic...

progestins like medroxyprogesterone acetate to suppress menstruation; and 5α-reductase inhibitors to prevent pattern hair loss. Sometimes another androgen instead...

In enzymology, an iron—cytochrome-c reductase (created 1972 as EC 1.9.99.1, transferred 2014 to EC 1.9.98.1) is an enzyme that catalyzes the chemical...

In enzymology, Delta24-sterol reductase (EC 1.3.1.72) is an enzyme that catalyzes the chemical reaction. 5α-cholesta-7,24-dien-3β-ol + NADPH     H+  ...

In enzymology, divinyl chlorophyllide a 8-vinyl-reductase (EC 1.3.1.75) is an enzyme that catalyzes the chemical reaction 3,8-divinylprotochlorophyllide...

dehydroascorbate reductase (DHAR) at the expense of GSH, yielding oxidized glutathione (GSSG). Finally GSSG is reduced by glutathione reductase (GR) using NADPH...

Cytochrome c nitrite reductase (ccNiR) (EC 1.7.2.2) is a bacterial enzyme that catalyzes the six electron reduction of nitrite to ammonia; an important...

Crotonyl-CoA reductase (EC 1.3.1.86, butyryl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme...

dihydroflavanol 4-reductase and leucoanthocyanidin reductase to yield catechin. The biosynthesis of catechin is shown below Leucocyanidin reductase (LCR) uses...

the anthocyanidin to colorless epicatechin by the enzyme anthocyanidin reductase (ANR). Many external factors can influence colour: light, temperature...

genitalia such as in conditions like Congenital adrenal hyperplasia and 5α-Reductase 2 deficiency. For many years, it was widely believed that in mammals,...

In enzymology, orotate reductase (NADPH) (EC 1.3.1.15) is an enzyme that catalyzes the chemical reaction (S)-hydroorotic acid + NADP+       H+   H+  ...

In enzymology, a 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) is an enzyme that catalyzes the chemical reaction D-glyceric acid + NAD+       H+  ...

Trimetrexate is a quinazoline derivative. It is a dihydrofolate reductase inhibitor. It has been used with leucovorin in treating pneumocystis pneumonia...

In enzymology, a xanthommatin reductase (EC 1.3.1.41) is an enzyme that catalyzes the chemical reaction 5,12-dihydroxanthommatin + NAD+ ⇌ {\displaystyle...

Riboflavin:NAD(P)+ oxidoreductase may refer to: Riboflavin reductase (NAD(P)H), a riboflavin reduction enzyme FMN reductase, a flavin mononucleotide reduction enzyme This...

In enzymology, 5-amino-6-(5-phosphoribosylamino)uracil reductase (EC 1.1.1.193) is an enzyme that catalyzes the chemical reaction...

Alcohol-forming fatty acyl-CoA reductase (EC 1.2.1.84, FAR (gene)) is an enzyme with systematic name long-chain acyl-CoA:NADPH reductase. This enzyme catalyses...

In enzymology, a dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) is an enzyme that catalyzes the chemical reaction dTDP-6-deoxy-L-mannose + NADP+ ⇌ {\displaystyle...

production of deoxyribonucleotides via inhibition of the enzyme ribonucleotide reductase by scavenging tyrosyl free radicals as they are involved in the reduction...

Dihydropteridine reductase deficiency (DHPRD) is a genetic disorder affecting the tetrahydrobiopterin (BH4) synthesis pathway, inherited in the autosomal...

In enzymology, a long-chain-fatty-acyl-CoA reductase (EC 1.2.1.50) is an enzyme that catalyzes the chemical reaction a long-chain aldehyde + CoA + NADP+...

Steroid 5-alpha-reductase 3, also known as 3-oxo-5-alpha-steroid 4-dehydrogenase 3, is an enzyme that in humans is encoded by the SRD5A3 gene. It is one...

In enzymology, pyrroline-2-carboxylate reductase (EC 1.5.1.1) is an enzyme that catalyzes the chemical reaction 1-pyrroline-2-carboxylic acid + NADH  ...

Identifiers EC no. 7.1.1.2 CAS no. 9079-67-8 Alt. names cytochrome c reductase, type 1 dehydrogenase, beta-NADH dehydrogenase dinucleotide, diaphorase...

Ferric-chelate reductase (NADPH) (EC 1.16.1.9, ferric chelate reductase, iron chelate reductase, NADPH:Fe3+-EDTA reductase, NADPH-dependent ferric reductase, yqjH...

products. DHEA-caproate ester (#121) has a IC50 of 0.049nM for the 5-alpha-reductase enzyme. List of carboxylic acids List of saturated fatty acids Caproate...

Mitochondrial complex II deficiency, also called CII deficiency, is a rare mitochondrial disease caused by deficiency of mitochondrial complex II, also...

(designated as type E). It forms a two-component system with a reductase (StyB, StyA2B). The reductase utilizes solely nicotinamide adenine dinucleotide to reduce...

Bis-gamma-glutamylcystine reductase (EC 1.8.1.13) is an enzyme that catalyzes the chemical reaction bis-γ-glutamylcystine + NADPH     H+   H+     2  ...

Ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa is a protein that in humans is encoded by the UQCRQ gene. This ubiqinone-binding protein...

form of folate, and must undergo enzymatic reduction by dihydrofolate reductase (DHFR) to become biologically active. Systematic reviews suggest that...

In enzymology, a ferredoxin—nitrite reductase (EC 1.7.7.1) is an enzyme that catalyzes the chemical reaction NH3 + 2 H2O + 6 oxidized ferredoxin ⇌ {\displaystyle...

periplasmic respiratory arsenate reductase and a cytoplasmic arsenate reductase. The anaerobic respiratory arsenate reductase reduces AsO43− to As(OH)3. It...

In enzymology, a trimethylamine-N-oxide reductase (cytochrome c) (EC 1.7.2.3) is an enzyme that catalyzes the chemical reaction trimethylamine + 2 (ferricytochrome...

Saxagliptin Sitagliptin Teneligliptin Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase...

In enzymology, a nitrite reductase (NO-forming) (EC 1.7.2.1) is an enzyme that catalyzes the chemical reaction nitric oxide + H2O + ferricytochrome c...

Aldo-keto reductase family 1 member C4, also known as 3α-Hydroxysteroid dehydrogenase type 1 (3α-HSD1), is an enzyme that in humans is encoded by the...

molybdopterin cofactor include xanthine oxidase, DMSO reductase, sulfite oxidase, and nitrate reductase. The only molybdenum-containing enzymes that do not...

be regained from the reduction. The enzyme dissimilatory (bi)sulfite reductase, dsrAB (EC 1.8.99.5), that catalyzes the last step of dissimilatory sulfate...

inhibitor DNA precursors/ antimetabolites (S phase) Folic acid Dihydrofolate reductase inhibitor (Aminopterin Methotrexate# Pemetrexed Pralatrexate) Thymidylate...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

Statins act by inhibiting the enzyme hydroxymethylglutaryl CoA reductase (HMG-CoA-reductase) in the liver. In response, the liver produces more LDL receptors...

Arsenate reductase (cytochrome c) (EC 1.20.2.1, arsenite oxidase) is an enzyme with systematic name arsenite:cytochrome c oxidoreductase. This enzyme...

In enzymology, a prostaglandin-E2 9-reductase (EC 1.1.1.189) is an enzyme that catalyzes the chemical reaction prostaglandin E2 + NADP+       H+   H+...

Pterin-4 alpha-carbinolamine dehydratase deficiency (PCDD) is one of the known forms of tetrahydrobiopterin deficiency. This condition is associated with...

Hyperlysinemia Other names Lysine alpha-ketoglutarate reductase deficiency Lysine Specialty Endocrinology ...

Diacetyl reductase ((S)-acetoin forming) (EC 1.1.1.304, (S)-acetoin dehydrogenase) is an enzyme with systematic name (S)-acetoin:NAD+ oxidoreductase....

NAD+ to NADH. This reduced cofactor is then a substrate for any of the reductases in the cell that require electrons to reduce their substrates. Therefore...

17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B) (EC 1.1.1.51), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction...

Saxagliptin Sitagliptin Teneligliptin Trelagliptin Vildagliptin Other Aldose reductase inhibitors Epalrestat Fidarestat§ Ranirestat† Tolrestat‡ Zenarestat§ Alpha-glucosidase...

In enzymology, mannuronate reductase (EC 1.1.1.131) is an enzyme that catalyzes the chemical reaction D-mannonic acid + NAD+       H+   H+   D-mannuronic...

In enzymology, a benzoyl-CoA reductase (EC 1.3.7.8) is an enzyme that catalyzes the chemical reaction benzoyl-CoA + reduced acceptor + 2 ATP + 2 H2O ⇌...

Nitric oxide reductase (cytochrome c) (EC 1.7.2.5) is an enzyme with systematic name nitrous oxide:ferricytochrome-c oxidoreductase. This enzyme catalyses...

In enzymology, a cis-2-enoyl-CoA reductase (NADPH) (EC 1.3.1.37) is an enzyme that catalyzes the chemical reaction acyl-CoA + NADP+ ⇌ {\displaystyle \rightleftharpoons...

Topical corticosteroids (e.g., hydrocortisone) Alopecia treatments 5α-Reductase inhibitors Alfatradiol Dutasteride Finasteride Saw palmetto extract Antiandrogens...

Phosphonoacetaldehyde reductase (NADH) (EC 1.1.1.309, PhpC) is an enzyme with systematic name 2-hydroxyethylphosphonate:NAD+ oxidoreductase. This enzyme...

In enzymology, a methylenetetrahydrofolate reductase (ferredoxin) (EC 1.5.7.1) is an enzyme that catalyzes the chemical reaction 5-methyltetrahydrofolate...

a complex 37-step process. This begins with the mevalonate or HMG-CoA reductase pathway, the target of statin drugs, which encompasses the first 18 steps...

Iron:rusticyanin reductase (EC 1.16.9.1, Cyc2) is an enzyme with systematic name Fe(II):rusticyanin oxidoreductase. This enzyme catalyses the following...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

(–)-epicatechin: cyanidin anthocyanidin reductase⟶NADPH (–)-epicatechin Path to (+)-catechin: leucocyanidin leucoanthocyanidin reductase⟶NADPH (+)-catechin Path to...

transfer reactions. Enzymes in this family include DMSO reductase, xanthine oxidase, nitrite reductase, and sulfite oxidase. Bioinorganic chemistry * Stephen...

Acrylyl-CoA reductase (NADPH) (EC 1.3.1.84) is an enzyme with systematic name propanoyl-CoA:NADP+ oxidoreductase. This enzyme catalyses the following...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

dihydrofolate reductase may reduce its effectiveness. These mutations decrease the binding affinity between pyrimethamine and dihydrofolate reductase via loss...

Benzil reductase ((S)-benzoin forming) (EC 1.1.1.320, YueD) is an enzyme with systematic name (S)-benzoin:NADP+ oxidoreductase. This enzyme catalyses...

isoprenoid precursor. IPP is an intermediate in the classical, HMG-CoA reductase pathway (commonly called the mevalonate pathway) and in the non-mevalonate...

protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although...

Chlorophyll(ide) b reductase (EC 1.1.1.294), chlorophyll b reductase, Chl b reductase) is an enzyme with systematic name 71-hydroxychlorophyllide-a:NAD(P)+...

Dehydrogenase/reductase SDR family member 4 is an enzyme that in humans is encoded by the DHRS4 gene. ENSG00000284807 GRCh38: Ensembl release 89: ENSG00000157326...

Acrylyl-CoA reductase (NADH) (EC 1.3.1.95) is an enzyme with systematic name propanoyl-CoA:NAD+ oxidoreductase. This enzyme catalyses the following chemical...

In enzymology, a 6-pyruvoyltetrahydropterin 2'-reductase (EC 1.1.1.220) is an enzyme that catalyzes the chemical reaction 6-lactoyl-5,6,7,8-tetrahydropterin...

In enzymology, a hydroxymethylglutaryl-CoA reductase (NADPH) (EC 1.1.1.34) is an enzyme that catalyzes the chemical reaction (R)-mevalonate + CoA + 2...

In enzymology, a nitrite reductase [NAD(P)H] (EC 1.7.1.4) is an enzyme that catalyzes the chemical reaction ammonium hydroxide + 3 NAD(P)+ + H2O ⇌ {\displaystyle...

Methionine-R-sulfoxide reductase B2, mitochondrial is an enzyme that in humans is encoded by the MSRB2 gene. The MRSB2 enzyme catalyzes the reduction...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

blocking the enzyme farnesyl diphosphate synthase (FPPS) in the HMG-CoA reductase pathway (also known as the mevalonate pathway). Bisphosphonates that contain...

CDP-4-dehydro-6-deoxyglucose reductase (EC 1.17.1.1) is an enzyme that catalyzes the chemical reaction CDP-4-dehydro-3,6-dideoxy-D-glucose + NAD(P)+ +...

ethyl methanesulfonate to generate a cell line lacking dihydrofolate reductase (DHFR) activity, referred to as CHO-DXB11 (also referred to as CHO-DUKX)...

the presence of varying concentrations of adrenodoxin reductase demonstrated that the reductase competes with P450scc for binding to adrenodoxin. These...

[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase (EC 3.1.3.47) catalyzes the reaction [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O...

The cytochrome b6f complex (plastoquinol/plastocyanin reductase or plastoquinol/plastocyanin oxidoreductase; EC 7.1.1.6) is an enzyme found in the thylakoid...

excessive amount of pre-ejaculate fluid, which may be treatable by a 5-alpha-reductase inhibitor, such as finasteride. Chudnovsky, A.; Niederberger, C.S. (2007)...

inhibitor DNA precursors/ antimetabolites (S phase) Folic acid Dihydrofolate reductase inhibitor (Aminopterin Methotrexate# Pemetrexed Pralatrexate) Thymidylate...

In enzymology, a vomilenine reductase (EC 1.5.1.32) is an enzyme that catalyzes the chemical reaction 1,2-dihydrovomilenine + NADP+ ⇌ {\displaystyle \rightleftharpoons...

v t e Drugs used in benign prostatic hyperplasia (G04C) 5α-Reductase inhibitors Dutasteride Epristeride Finasteride (+tadalafil) Alpha-1 blockers Alfuzosin...

5α-reductase, primarily in tissues where it exerts its effect, such as the prostate gland, hair follicles, and skin. Both pathways rely on 5α-reductase,...

Adenylyl-sulfate reductase (glutathione) (EC 1.8.4.9) is an enzyme that catalyzes the chemical reaction AMP + sulfite + glutathione disulfide ⇌ {\displaystyle...

Dehydrogenase/reductase SDR family member 9 is an enzyme that in humans is encoded by the DHRS9 gene. GRCh38: Ensembl release 89: ENSG00000073737 – Ensembl...

accumulation of deoxy-GTP which inhibits ribonucleotide reductase. Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides...

In enzymology, precorrin-6A reductase (EC 1.3.1.54) is an enzyme that catalyzes the chemical reaction precorrin-6A + NADP+       H+   H+   precorrin-6B...

A unique tetranuclear copper center has been found in nitrous-oxide reductase. Copper levels are closely regulated in both prokaryotic and eukaryotic...

Trans-2,3-enoyl-CoA reductase is an enzyme that in humans is encoded by the TECR gene. This gene encodes a multi-pass membrane protein that resides in...

flavoenzyme thioredoxin reductase, in a NADPH-dependent reaction. Thioredoxins act as electron donors to peroxidases and ribonucleotide reductase. The related glutaredoxins...

acyl-(acyl-carrier-protein) reductase (EC 1.2.1.80, long-chain acyl-[acp] reductase, fatty acyl-[acyl-carrier-protein] reductase, acyl-[acp] reductase) is an enzyme...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

Pyruvate dehydrogenase (NADP+) EC 1.2.1.51 is an enzyme that should not be confused with pyruvate dehydrogenase (acetyltransferase) EC 1.2.4.1. It catalyzes...

function ferric-chelate reductase (NADPH) activity metal ion binding transporter activity oxidoreductase activity cupric reductase activity channel activity...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

Topical corticosteroids (e.g., hydrocortisone) Alopecia treatments 5α-Reductase inhibitors Alfatradiol Dutasteride Finasteride Saw palmetto extract Antiandrogens...

Cohen-Kettenis, PT (August 2005). "Gender change in 46,XY persons with 5alpha-reductase-2 deficiency and 17beta-hydroxysteroid dehydrogenase-3 deficiency". Archives...

carbon dioxide to formylmethanofuran. The last step uses heterodisulfide reductase (Hdr) to reduce heterodisulfide into Coenzyme B and Coenzyme M using Fe4S4...

Arsenate reductase (donor) (EC 1.20.99.1) is an enzyme that catalyzes the chemical reaction arsenite + acceptor ⇌ {\displaystyle \rightleftharpoons }...

functionality of ene reductases emphasizes their crucial role in catalyzing a variety of reactions. One example is the ene-reductase Old-Yellow-Enzyme (OYE)...

respiration. It transfers electrons between Complexes III (Coenzyme Q – Cyt c reductase) and IV (Cyt c oxidase). Cytochrome c is highly water-soluble, unlike...

biological activity of folate in the body depends upon dihydrofolate reductase action in the liver which converts folate into tetrahydrofolate (THF)...

is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products...

converted into androstenone (a more potent and odorous pheromone) by 5α-reductase, which can subsequently be converted into 3α-androstenol or 3β-androstenol...

tetrahydrofolic acid is produced from dihydrofolic acid by dihydrofolate reductase. This reaction is inhibited by methotrexate. It is converted into 5...

pathways. For cancer, methotrexate competitively inhibits dihydrofolate reductase (DHFR), an enzyme that participates in the tetrahydrofolate synthesis...

activities including hepatoprotection, anti-tumor effects, and 5-alpha reductase inhibition. Nishitoba, Tsuyoshi; Goto, Sanae; Sato, Hiroji; Sakamura,...

with zinc sulfate in vitro was found to be a potent (90% inhibition) 5α-reductase inhibitor, similar to the hair loss drugs finasteride and dutasteride...

In enzymology, a GDP-4-dehydro-6-deoxy-D-mannose reductase (EC 1.1.1.281) is an enzyme that catalyzes the chemical reaction GDP-6-deoxy-D-mannose + NAD(P)+...

ferredoxin reductase, keto-valine-ferredoxin oxidoreductase, ketoisovalerate ferredoxin reductase, and 2-oxoisovalerate ferredoxin reductase. Enzyme 1...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

inhibitor DNA precursors/ antimetabolites (S phase) Folic acid Dihydrofolate reductase inhibitor (Aminopterin Methotrexate# Pemetrexed Pralatrexate) Thymidylate...

1.14.13.39 specifically refers to synthases with linked oxygenase and reductase domains, i.e. "catalytically self-sufficient" NO synthases. This kind...

hydroxyl group. The reaction requires NADH and is catalyzed by aldose reductase. Glucose reduction is the first step of the polyol pathway of glucose...

belongs to the family of biflavonoids and is an inhibitor of HMG-CoA reductase. Tuansulong, KA; Hutadilok-Towatana, N; Mahabusarakam, W; Pinkaew, D;...

names in common use include glutathione-dependent thiosulfate reductase, sulfane reductase, and sulfane sulfurtransferase. This enzyme participates in glutathione...

Sulfite reductase (NADPH) (EC 1.8.1.2, sulfite (reduced nicotinamide adenine dinucleotide phosphate) reductase, NADPH-sulfite reductase, NADPH-dependent...

Sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming) (EC 1.1.1.325) is an enzyme with systematic name L-threo-7,8-dihydrobiopterin:NADP+ oxidoreductase...

a chemically similar androgen, in cells containing the enzyme 5-alpha reductase. Both androgens exert their influence through binding with the androgen...

Dehydrogenase/reductase SDR family member 2 is an enzyme that in humans is encoded by the DHRS2 gene. GRCh38: Ensembl release 89: ENSG00000100867 – Ensembl...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

December 2016. Ozturk; et al. (2008). "Glyphosate inhibition of ferric reductase activity in iron deficient sunflower roots". New Phytologist. 177 (4):...

Ribonucleotide reductase inhibitor (Gemcitabine#) Hypomethylating agent (Azacitidine Decitabine) Deoxyribonucleotide Ribonucleotide reductase inhibitor (Hydroxycarbamide#)...

treatment depends on the cause. BPH may respond to alpha blocker and 5-alpha-reductase inhibitor therapy, or surgically with prostatectomy or transurethral resection...

Vitamin K epOxide Reductase Complex subunit 1 (VKORC) is an enzyme that in humans is encoded by the VKORC1 gene. This enzymatic protein complex is responsible...

the reduced state by NADPH. This conversion is catalyzed by glutathione reductase: NADPH + GSSG + H2O → 2 GSH + NADP+ + OH− GSH protects cells by neutralising...

24-Dehydrocholesterol reductase is a protein that in humans is encoded by the DHCR24 gene. This gene encodes a flavin adenine dinucleotide (FAD)-dependent...

In enzymology, a L-methionine (R)-S-oxide reductase (EC 1.8.4.14) is an enzyme that catalyzes the chemical reaction L-methionine + thioredoxin disulfide...

In enzymology, a 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) (EC 1.1.1.212) is an enzyme that catalyzes the chemical reaction...

ferredoxin is the last electron acceptor thus reducing the enzyme NADP+ reductase. It accepts electrons produced from sunlight-excited chlorophyll and transfers...

space of time.[medical citation needed] While it can be metabolized by 5α-reductase into methyl-1-testosterone (17α-methyl-δ1-DHT), a more potent AAS, the...

which, until recently, were believed to work by inhibiting dihydrofolate reductase. Examples include:[citation needed] Proguanil (>cycloguanil) Chlorproguanil...

Very-long-chain enoyl-CoA reductase (EC 1.3.1.93, TSC13 (gene name), CER10 (gene)) is an enzyme with systematic name very-long-chain acyl-CoA:NADP+ oxidoreductase...

Pyrroline-5-carboxylate reductase 1, mitochondrial is an enzyme that in humans is encoded by the PYCR1 gene. This gene encodes an enzyme that catalyzes...

blocking a crucial protein in color production, called dihydroflavonol 4-reductase (DFR), and adding a variant of that protein that would not be blocked...

and metabolism Steroid reductases 5α-Reductase (1, 2, 3) – androgen and neurosteroid synthesis, progestogen metabolism 5β-Reductase – androgen and progestogen...

MurB reductase, UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylglucosamine-enoylpyruvate reductase, UDP-GlcNAc-enoylpyruvate reductase, uridine...

humans, the enzyme is reduced in this process by methionine synthase reductase (MTRR), which consists of flavodoxin-like and ferrodoxin-NADP+ oxidoreductase...

In enzymology, a cob(II)alamin reductase (EC 1.16.1.4) is an enzyme that catalyzes the chemical reaction 2 cob(I)alamin + NAD+ ⇌ {\displaystyle \rightleftharpoons...

In enzymology, a GDP-4-dehydro-D-rhamnose reductase (EC 1.1.1.187) is an enzyme that catalyzes the chemical reaction GDP-6-deoxy-D-mannose + NAD(P)+ ⇌...

either directly exert effects on target tissues or be metabolized by 5α-reductase into DHT or aromatized to estradiol (E2). Both testosterone and DHT bind...

Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase may refer to: NADH dehydrogenase NADH:ubiquinone reductase (non-electrogenic) This set index page lists...

In enzymology, a 8-oxocoformycin reductase (EC 1.1.1.235) is an enzyme that catalyzes the chemical reaction coformycin + NADP+ ⇌ {\displaystyle \rightleftharpoons...

tolerated. Statins competitively inhibit hydroxymethylglutaryl (HMG) CoA reductase which is used in the biosynthesis of cholesterol and they include atorvastatin...

In enzymology, a 4-hydroxybenzoyl-CoA reductase (EC 1.3.7.9) is an enzyme found in some bacteria and archaea that catalyzes the chemical reaction benzoyl-CoA...