Pyrimidone

Pyrimidone
2-Pyrimidone
2-Pyrimidone
4-Pyrimidone
4-Pyrimidone
Names
Preferred IUPAC name
1H-Pyrimidin-6-one
Other names
Hydroxypyrimidine; Pyrimidinone
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C4H4N2O/c7-4-1-2-5-3-6-4/h1-3H,(H,5,6,7)
    Key: DNCYBUMDUBHIJZ-UHFFFAOYSA-N
  • O=C1NC=NC=C1
Properties
C4H4N2O
Molar mass 96.089 g·mol−1
Appearance White to light yellow powder
Melting point 163 to 168 °C (325 to 334 °F; 436 to 441 K)
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Respiratory system, eye, skin irritation
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Pyrimidone is the name given to either of two heterocyclic compounds with the formula C4H4N2O: 2-pyrimidone[1] and 4-pyrimidone. The compounds can also be called 2-hydroxypyrimidine or 4-hydroxypyrimidine respectively, based on a substituted pyrimidine, or 1,3-diazine, ring.

Applications

Derivatives

Derivatives of pyrimidone are the basis of many other biological molecules, including:

Pyrimidone-derived antiulcer drugs include temelastine, icotidine, donetidine, and lupitidine.

Methylated pyrimidone derivatives undergo pH-switched photoisomerization to the corresponding Dewar arene. The process can be used for long-term thermal energy storage with an energy density of 1.6 MJ/kg[2], approximately double that of a lithium ion battery.


References

  1. ^ Manglik, Mr Rohit (23 June 2023). Basics of Organic Chemistry. EduGorilla Publication. p. 430. ISBN 978-93-6817-864-4.
  2. ^ Nguyen, Han P. Q.; Maertens, Alexander J.; Baker, Benjamin A.; Wu, Nathan M.-W.; Ye, Zihao; Zhou, Qingyang; Qiu, Qianfeng; Kaur, Navneet; Berkinsky, David B.; Shulenberger, Katherine E.; Houk, K. N.; Han, Grace G. D. (2026-02-12). "Molecular solar thermal energy storage in Dewar pyrimidone beyond 1.6 MJ/kg". Science. 0 (0) eaec6413. doi:10.1126/science.aec6413.
Stub icon

This article about a heterocyclic compound is a stub. You can help Wikipedia by adding missing information.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.