Search Results: Plexins
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Plexin
Sabtu, 2025-10-04 20:11:01effects. All plexins have an extracellular SEMA domain at their N-terminus. This is a structural motif common among all semaphorins and plexins and is responsible...
Click to read more »Semaphorin
Sabtu, 2026-03-14 10:20:33receptors are called plexins, with neuropilins as their co-receptors in many cases. The main receptors for semaphorins are plexins, which have established...
Click to read more »Plexin-B1
Jumat, 2026-02-13 18:07:52PMID 11035813. "Plexin-B1". UniProt. Retrieved 13 February 2026. Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG (Oct 9, 2002). "B plexins activate Rho...
Click to read more »Plexin A1
Jumat, 2025-07-18 00:56:15PMID 10520994. S2CID 18167425. Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »Synaptic pruning
Senin, 2026-04-20 12:35:45synaptic connections. Semaphorin ligands and the receptors neuropilins and plexins are used to induce retraction of the axons to initiate hippocampo-septal...
Click to read more »PLXNB2
Sabtu, 2025-07-19 13:57:51Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene. Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that...
Click to read more »PLXNB3
Rabu, 2025-10-22 10:33:39Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM (Oct 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »PLXNA4A
Rabu, 2025-11-12 05:15:51glycosylation sites. It also contains domains consistent with other class A plexins including a Sema domain, three "Met-related sequences"/cysteine clusters...
Click to read more »PLXNA2
Sabtu, 2025-07-19 13:57:471001/archpsyc.64.3.318. PMID 17339520. Negishi M, Oinuma I, Katoh H (2005). "Plexins: axon guidance and signal transduction". Cell. Mol. Life Sci. 62 (12):...
Click to read more »Semaphorin 3E
Senin, 2025-10-20 08:15:21proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based...
Click to read more »PLXND1
Senin, 2026-03-30 09:34:053.169. PMID 9734811. Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »SEMA4D
Sabtu, 2025-07-19 14:15:4433376. PMID 8969198. Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »Chromosome 17
Selasa, 2025-07-15 10:59:52protein ORMDL sphingolipid biosynthesis regulator 3 PLXDC1: encoding protein Plexin domain-containing protein 1 PNPO: encoding enzyme Pyridoxine-5'-phosphate...
Click to read more »Semaphorin-3A
Rabu, 2025-07-16 05:17:21glioma cells express semaphorins and their receptors, neuropilins and plexins". Glia. 42 (4): 379–89. doi:10.1002/glia.10210. PMID 12730958. S2CID 45643250...
Click to read more »Neuropilin 2
Kamis, 2025-07-17 01:04:33L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »Optic chiasm
Rabu, 2026-04-29 01:09:50(Sema6D) expressed at the midline, which form a complex that signals to Nr-CAM/Plexin-A1 receptors on crossing RGC axons. Since all vertebrates, even the earliest...
Click to read more »VEGF receptor
Selasa, 2025-06-24 15:47:51Blondelle J, Singh MK, Flaherty KM, Means PC, et al. (August 2011). "Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1"...
Click to read more »Hailan Hu
Rabu, 2026-04-22 18:24:57explored the role of the plexin receptor and the Rho family GTPases in central nervous system development in Drosophila. Plexins are receptors involved...
Click to read more »PLXNA3
Rabu, 2025-10-22 11:16:03Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »Retinal ganglion cell
Minggu, 2026-01-25 14:50:36RGCs and the midline glia and acts along with Sema6D, mediated via the plexin-A1 receptor. VEGF-A is released from the midline directs RGCs to take a...
Click to read more »Sema domain
Rabu, 2021-07-07 02:02:22also occur in the hepatocyte growth factor receptor (Uniprot: P08581), Plexin-A3 (Uniprot: P51805) and in viral proteins. CD100 (also called SEMA4D) is...
Click to read more »Neuropilin
Jumat, 2025-07-18 12:13:15documented to regulate neurogenesis and angiogenesis by complexing with Plexin receptors/class-3 semaphorin ligands and Vascular Endothelial Growth Factor...
Click to read more »Neuroregeneration
Minggu, 2026-05-17 22:36:45and inhibits remyelination. Sema 4D(Semaphorin 4D) functions through the PlexinB1 receptor and inhibits remyelination. Sema 3A (Semaphorin 3A) is present...
Click to read more »SEMA7A
Sabtu, 2025-10-04 20:06:37L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »Hereditary spastic paraplegia
Jumat, 2026-03-06 14:29:27the association of L1CAM with neuropilin-1. Neuropilin-1 interacts with Plexin-A proteins to form the Semaphorin-3A receptor complex. Semaphorin-a3A is...
Click to read more »List of human clusters of differentiation
Selasa, 2026-02-24 05:42:22as Huntington's chorea, fragile X syndrome and myotonic dystrophy. CD232 Plexin-C1 (PLXNC1 gene); also called Virus-encoded semaphorin protein receptor...
Click to read more »PLXDC1
Jumat, 2025-07-18 00:56:29Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene. Plexin PLXDC2 Protein domain GRCh38: Ensembl release 89:...
Click to read more »SEMA3F
Kamis, 2025-07-17 01:34:47PMID 15520858. Gu C, Yoshida Y, Livet J, et al. (2005). "Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins". Science. 307...
Click to read more »C1orf21
Sabtu, 2026-03-21 21:24:45protein 13 (NLPR13) Involved in inflammation Semaphorin-3C (SEMA3C) Binds to plexin family members and plays an important role in the regulation of developmental...
Click to read more »Neuropilin 1
Kamis, 2025-07-17 01:04:30L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...
Click to read more »Hepatocyte growth factor receptor
Minggu, 2025-09-28 03:17:18regulation of autophagy branching morphogenesis of an epithelial tube semaphorin-plexin signaling pathway signal transduction positive regulation of transcription...
Click to read more »Alain Chédotal
Rabu, 2026-01-21 07:16:03Corey S.; Poo, Mu-Ming; Tessier-Lavigne, Marc; Comoglio, Paolo M. (1999). "Plexins Are a Large Family of Receptors for Transmembrane, Secreted, and GPI-Anchored...
Click to read more »Glial cell line-derived neurotrophic factor
Senin, 2026-02-16 13:46:37chemoattraction of axon commissural neuron axon guidance regulation of semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...
Click to read more »Tropic cues involved in growth cone guidance
Sabtu, 2026-05-23 01:58:03Npn1 receptor transmits signaling to adjacent surface molecules, known as Plexins; this is necessary because the Npn1 receptor lacks an intracellular domain...
Click to read more »AKT1
Jumat, 2026-05-22 22:30:49PMID 11410591. Turner LJ, Nicholls S, Hall A (Aug 2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32): 33199–205. doi:10...
Click to read more »RAC1
Minggu, 2024-09-29 12:34:12cerebral cortex radially oriented cell migration cell migration semaphorin-plexin signaling pathway positive regulation of stress fiber assembly axon guidance...
Click to read more »FLNA
Jumat, 2026-01-16 01:16:41regulation of cell migration wound healing, spreading of cells semaphorin-plexin signaling pathway formation of radial glial scaffolds cerebral cortex development...
Click to read more »PLXDC2
Jumat, 2025-07-18 00:56:31Plexin domain-containing protein 2 is a protein that in humans is encoded by the PLXDC2 gene. GRCh38: Ensembl release 89: ENSG00000120594 – Ensembl, May...
Click to read more »SEMA4G
Kamis, 2025-07-17 01:34:49proteins which possess a semaphoring (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Semaphorins...
Click to read more »SEMA5A
Sabtu, 2025-10-11 22:17:54P, Fazzari P, Gilestro GF, Barberis D, Giordano S, et al. (July 2004). "Plexin-B3 is a functional receptor for semaphorin 5A". EMBO Reports. 5 (7): 710–714...
Click to read more »PTK7
Senin, 2025-08-18 18:18:54neural crest cell migration) and appears to have similar functions for plexin and Flt-1 pathways. PTK7 was identified to be highly expressed in colon...
Click to read more »GRLF1
Rabu, 2025-07-16 04:45:32Tamagnone L (Oct 2005). "p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling" (PDF). Journal of Cell Science...
Click to read more »SEMA3C
Sabtu, 2025-07-19 14:15:36glioma cells express semaphorins and their receptors, neuropilins and plexins". Glia. 42 (4): 379–89. doi:10.1002/glia.10210. PMID 12730958. S2CID 45643250...
Click to read more »Pioneer axon
Selasa, 2025-08-26 07:50:40ideal regions. Receptor complexes for semaphorins include neuropilins and plexins. The Slit-Robo cell signaling pathway plays an important role in guiding...
Click to read more »Axon guidance
Selasa, 2026-05-19 09:30:18axonal repellents, and activate complexes of cell-surface receptors called plexins and neuropilins. Cell adhesion molecules (CAMs): Integral membrane proteins...
Click to read more »Co-receptor
Senin, 2026-04-27 14:13:07family mediates binding of VEGF in conjunction with the VEGFR1/VEGFR2 and Plexin signaling receptors, and therefore also plays a role in tumor vascular development...
Click to read more »Chromosome 10
Selasa, 2026-03-17 14:46:52PLEKHS1 encoding protein Pleckstrin homology domain containing S1 PLXDC2: plexin domain-containing protein 2 PRAP1: encoding protein Proline rich acidic...
Click to read more »Multiple epidermal growth factor-like domains 8
Kamis, 2026-05-07 02:58:00epidermal growth factor (EGF). PSI domain: domain found in plexins, semaphorins and integrins. Plexin are involved in the development of neural and epithelial...
Click to read more »Lataisia Jones
Kamis, 2026-03-05 10:14:08brain hemispheres. Jones took on two different research projects: studying Plexin-A1 during the postnatal development of the corpus callosum and how Tsc1...
Click to read more »SEMA4F
Sabtu, 2025-07-19 14:15:46negative regulation of axon extension involved in axon guidance semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...
Click to read more »FARP2
Kamis, 2025-07-17 23:33:36signal transduction regulation of Rho protein signal transduction semaphorin-plexin signaling pathway hair cycle process Sources:Amigo / QuickGO Orthologs Species...
Click to read more »Catch bond
Senin, 2025-11-17 22:11:46Reinherz EL (January 2014). "Dynamic control of beta1 integrin adhesion by the plexinD1-sema3E axis". Proceedings of the National Academy of Sciences of the United...
Click to read more »Neuronal lineage marker
Senin, 2025-11-10 07:34:38LINGO-1; MAP1B/MAP5; Mical-3; NAP-22; NGFR; Nestin; Netrin-1; Neuropilin; Plexin-A1; RanBPM; Semaphorin 3A; Semaphorin 3F; Semaphorin 4D; Slit2; Slit3; Staufen;...
Click to read more »GnRH neuron
Selasa, 2025-09-30 07:06:52regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex". Journal of Cell Biology. 183 (3): 555–66. doi:10.1083/jcb...
Click to read more »C-Met inhibitor
Minggu, 2026-02-22 20:44:44Sema domain (Semaphorin-like), PSI (Plexins, Semaphorins, Integrins), IPT domain (Immunoglobulin-like, Plexins, Transcription factors) and PTK (Protein...
Click to read more »SH3BP1
Jumat, 2025-07-18 01:19:51negative regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway phagocytosis cell migration positive regulation of GTPase...
Click to read more »HAND2
Jumat, 2025-11-14 03:36:32odontogenesis of dentin-containing tooth positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis multicellular...
Click to read more »Collapsin response mediator protein family
Senin, 2023-12-11 05:06:35neuropilin 1 and plexin A1. While some of the other class of semaphorins directly bind to plexin receptors, Sema3A does not bind to plexin directly. Instead...
Click to read more »Chenghua Gu
Minggu, 2026-05-03 23:02:18M.; Kolodkin, Alex L.; Ginty, David D. (2005-01-14). "Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins". Science. 307...
Click to read more »ARHGEF12
Selasa, 2025-07-15 10:53:08Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG (October 2002). "B plexins activate Rho through PDZ-RhoGEF". FEBS Letters. 529 (2–3): 168–72. Bibcode:2002FEBSL...
Click to read more »ARHGDIA
Rabu, 2025-07-16 23:30:51transduction regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway regulation of catalytic activity Rho protein signal transduction...
Click to read more »Rif (GTPase)
Jumat, 2025-10-03 00:15:48Mellor H (March 2015). "The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction". Neuroscience Letters. 590: 178–83. doi:10...
Click to read more »SEMA4A
Sabtu, 2025-07-19 14:15:38angiogenesis T cell differentiation involved in immune response semaphorin-plexin signaling pathway negative chemotaxis neural crest cell migration positive...
Click to read more »ARHGEF11
Kamis, 2025-07-17 22:41:52Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG (Oct 2002). "B plexins activate Rho through PDZ-RhoGEF". FEBS Letters. 529 (2–3): 168–72. doi:10...
Click to read more »List of A1 genes, proteins or receptors
Selasa, 2022-03-15 01:06:59protein, member A1 PCDHA4 Phospholipase A1 Phosphorylase kinase, alpha 1 Plexin A1 Polymerase (DNA directed), alpha 1 Potassium large conductance calcium-activated...
Click to read more »RIT2
Kamis, 2025-12-18 19:08:08Hartwig C, Veske A, Krejcova S, Rosenberger G, Finckh U (August 2005). "Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with...
Click to read more »MICALL1
Jumat, 2025-07-18 00:26:05"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...
Click to read more »SEMA3B
Sabtu, 2025-07-19 14:15:35axon extension involved in axon guidance chemorepulsion of axon semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...
Click to read more »SEMA4B
Sabtu, 2025-07-19 14:15:40347. PMID 11214970. Swiercz JM, Kuner R, Behrens J, Offermanns S (2002). "Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone...
Click to read more »SEMA4C
Sabtu, 2025-07-19 14:15:42closure positive regulation of stress-activated MAPK cascade semaphorin-plexin signaling pathway negative chemotaxis neural crest cell migration positive...
Click to read more »Proteases in angiogenesis
Selasa, 2026-01-06 07:06:51membrane-bound form by MT1-MMP (MMP-14) in tumor cells; it then interacts with plexin B1 on endothelial cells, promoting pro-angiogenic chemotaxis. Shedding of...
Click to read more »Sortase
Rabu, 2025-11-12 05:40:07non-canonical catalysis of the Rap GTPase activating protein domain of plexin". eLife. 2 e01279. doi:10.7554/eLife.01279. PMC 3787391. PMID 24137545....
Click to read more »SEMA6C
Selasa, 2025-07-22 04:30:15axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...
Click to read more »MICAL3
Kamis, 2025-07-17 00:56:28"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...
Click to read more »Rnd1
Rabu, 2025-07-16 05:15:39(Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"...
Click to read more »WNT2
Kamis, 2025-07-17 01:59:24mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling". Proc. Natl. Acad. Sci. U.S.A. 106 (33): 13933–8. Bibcode:2009PNAS...
Click to read more »SEMA6A
Kamis, 2025-07-17 01:34:51axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...
Click to read more »MICAL1
Jumat, 2025-07-18 00:26:00"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...
Click to read more »Slit-Robo
Senin, 2026-06-01 01:49:15however, full length Slit2, through interactions with semaphorin receptor plexin-A4 regulates axonal branching. Interactions between Slit and Robo in this...
Click to read more »MAP6
Senin, 2025-10-20 08:14:16from the hippocampus, where it is involved with the receptors Neuropilin1, Plexin D1, and VEGFR2—which together make up the tripartite Semaphorin 3E receptor...
Click to read more »RACGAP1
Sabtu, 2025-10-04 01:39:061016/S1534-5807(01)00110-1. PMID 11782313. Vikis HG, Li W, Guan KL (April 2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"...
Click to read more »RAPGEF2
Sabtu, 2025-07-19 14:07:04Aurandt J, Vikis HG, Gutkind JS, et al. (2002). "The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide...
Click to read more »NPTX1
Sabtu, 2025-07-19 13:43:45PMID 17151277. Takahashi T, Strittmatter SM (2001). "Plexina1 autoinhibition by the plexin sema domain". Neuron. 29 (2): 429–39. doi:10.1016/S0896-6273(01)00216-1...
Click to read more »Fast endophilin-mediated endocytosis
Jumat, 2026-02-06 22:51:28Acetylcholine receptor 4 EGFR HGFR VEGFR PDGFR NGFR IGFR Tetrameric IL2R PlexinA1 ROBO1 Cholera toxins Shiga toxins Membrane scission is the process by...
Click to read more »MICAL2
Sabtu, 2025-07-19 13:32:15"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...
Click to read more »ARHGEF6
Rabu, 2025-10-22 10:10:356796-6807.2001. PMC 99857. PMID 11564864. Vikis HG, Li W, Guan KL (2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"...
Click to read more »FARP1
Senin, 2025-12-22 04:41:56of spinal motor neuron subtypes through transmembrane Semaphorin6A and PlexinA4 signaling". Neuron. 61 (3): 359–72. doi:10.1016/j.neuron.2008.12.022....
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