Search Results: Plexins

Redirect to:


Plexin
Sabtu, 2025-10-04 20:11:01

effects. All plexins have an extracellular SEMA domain at their N-terminus. This is a structural motif common among all semaphorins and plexins and is responsible...

Click to read more »
Semaphorin
Sabtu, 2026-03-14 10:20:33

receptors are called plexins, with neuropilins as their co-receptors in many cases. The main receptors for semaphorins are plexins, which have established...

Click to read more »
Plexin-B1
Jumat, 2026-02-13 18:07:52

PMID 11035813. "Plexin-B1". UniProt. Retrieved 13 February 2026. Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG (Oct 9, 2002). "B plexins activate Rho...

Click to read more »
Plexin A1
Jumat, 2025-07-18 00:56:15

PMID 10520994. S2CID 18167425. Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
Synaptic pruning
Senin, 2026-04-20 12:35:45

synaptic connections. Semaphorin ligands and the receptors neuropilins and plexins are used to induce retraction of the axons to initiate hippocampo-septal...

Click to read more »
PLXNB2
Sabtu, 2025-07-19 13:57:51

Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene. Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that...

Click to read more »
PLXNB3
Rabu, 2025-10-22 10:33:39

Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM (Oct 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
PLXNA4A
Rabu, 2025-11-12 05:15:51

glycosylation sites. It also contains domains consistent with other class A plexins including a Sema domain, three "Met-related sequences"/cysteine clusters...

Click to read more »
PLXNA2
Sabtu, 2025-07-19 13:57:47

1001/archpsyc.64.3.318. PMID 17339520. Negishi M, Oinuma I, Katoh H (2005). "Plexins: axon guidance and signal transduction". Cell. Mol. Life Sci. 62 (12):...

Click to read more »
Semaphorin 3E
Senin, 2025-10-20 08:15:21

proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based...

Click to read more »
PLXND1
Senin, 2026-03-30 09:34:05

3.169. PMID 9734811. Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
SEMA4D
Sabtu, 2025-07-19 14:15:44

33376. PMID 8969198. Tamagnone L, Artigiani S, Chen H, et al. (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
Chromosome 17
Selasa, 2025-07-15 10:59:52

protein ORMDL sphingolipid biosynthesis regulator 3 PLXDC1: encoding protein Plexin domain-containing protein 1 PNPO: encoding enzyme Pyridoxine-5'-phosphate...

Click to read more »
Semaphorin-3A
Rabu, 2025-07-16 05:17:21

glioma cells express semaphorins and their receptors, neuropilins and plexins". Glia. 42 (4): 379–89. doi:10.1002/glia.10210. PMID 12730958. S2CID 45643250...

Click to read more »
Neuropilin 2
Kamis, 2025-07-17 01:04:33

L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
Optic chiasm
Rabu, 2026-04-29 01:09:50

(Sema6D) expressed at the midline, which form a complex that signals to Nr-CAM/Plexin-A1 receptors on crossing RGC axons. Since all vertebrates, even the earliest...

Click to read more »
VEGF receptor
Selasa, 2025-06-24 15:47:51

Blondelle J, Singh MK, Flaherty KM, Means PC, et al. (August 2011). "Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1"...

Click to read more »
Hailan Hu
Rabu, 2026-04-22 18:24:57

explored the role of the plexin receptor and the Rho family GTPases in central nervous system development in Drosophila. Plexins are receptors involved...

Click to read more »
PLXNA3
Rabu, 2025-10-22 11:16:03

Winberg ML, Goodman CS, Poo M, Tessier-Lavigne M, Comoglio PM (1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
Retinal ganglion cell
Minggu, 2026-01-25 14:50:36

RGCs and the midline glia and acts along with Sema6D, mediated via the plexin-A1 receptor. VEGF-A is released from the midline directs RGCs to take a...

Click to read more »
Sema domain
Rabu, 2021-07-07 02:02:22

also occur in the hepatocyte growth factor receptor (Uniprot: P08581), Plexin-A3 (Uniprot: P51805) and in viral proteins. CD100 (also called SEMA4D) is...

Click to read more »
Neuropilin
Jumat, 2025-07-18 12:13:15

documented to regulate neurogenesis and angiogenesis by complexing with Plexin receptors/class-3 semaphorin ligands and Vascular Endothelial Growth Factor...

Click to read more »
Neuroregeneration
Minggu, 2026-05-17 22:36:45

and inhibits remyelination. Sema 4D(Semaphorin 4D) functions through the PlexinB1 receptor and inhibits remyelination. Sema 3A (Semaphorin 3A) is present...

Click to read more »
SEMA7A
Sabtu, 2025-10-04 20:06:37

L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
Hereditary spastic paraplegia
Jumat, 2026-03-06 14:29:27

the association of L1CAM with neuropilin-1. Neuropilin-1 interacts with Plexin-A proteins to form the Semaphorin-3A receptor complex. Semaphorin-a3A is...

Click to read more »
List of human clusters of differentiation
Selasa, 2026-02-24 05:42:22

as Huntington's chorea, fragile X syndrome and myotonic dystrophy. CD232 Plexin-C1 (PLXNC1 gene); also called Virus-encoded semaphorin protein receptor...

Click to read more »
PLXDC1
Jumat, 2025-07-18 00:56:29

Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene. Plexin PLXDC2 Protein domain GRCh38: Ensembl release 89:...

Click to read more »
SEMA3F
Kamis, 2025-07-17 01:34:47

PMID 15520858. Gu C, Yoshida Y, Livet J, et al. (2005). "Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins". Science. 307...

Click to read more »
C1orf21
Sabtu, 2026-03-21 21:24:45

protein 13 (NLPR13) Involved in inflammation Semaphorin-3C (SEMA3C) Binds to plexin family members and plays an important role in the regulation of developmental...

Click to read more »
Neuropilin 1
Kamis, 2025-07-17 01:04:30

L, Artigiani S, Chen H, He Z, Ming GI, Song H, et al. (October 1999). "Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored...

Click to read more »
Hepatocyte growth factor receptor
Minggu, 2025-09-28 03:17:18

regulation of autophagy branching morphogenesis of an epithelial tube semaphorin-plexin signaling pathway signal transduction positive regulation of transcription...

Click to read more »
Alain Chédotal
Rabu, 2026-01-21 07:16:03

Corey S.; Poo, Mu-Ming; Tessier-Lavigne, Marc; Comoglio, Paolo M. (1999). "Plexins Are a Large Family of Receptors for Transmembrane, Secreted, and GPI-Anchored...

Click to read more »
Glial cell line-derived neurotrophic factor
Senin, 2026-02-16 13:46:37

chemoattraction of axon commissural neuron axon guidance regulation of semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...

Click to read more »
Tropic cues involved in growth cone guidance
Sabtu, 2026-05-23 01:58:03

Npn1 receptor transmits signaling to adjacent surface molecules, known as Plexins; this is necessary because the Npn1 receptor lacks an intracellular domain...

Click to read more »
AKT1
Jumat, 2026-05-22 22:30:49

PMID 11410591. Turner LJ, Nicholls S, Hall A (Aug 2004). "The activity of the plexin-A1 receptor is regulated by Rac". J. Biol. Chem. 279 (32): 33199–205. doi:10...

Click to read more »
RAC1
Minggu, 2024-09-29 12:34:12

cerebral cortex radially oriented cell migration cell migration semaphorin-plexin signaling pathway positive regulation of stress fiber assembly axon guidance...

Click to read more »
FLNA
Jumat, 2026-01-16 01:16:41

regulation of cell migration wound healing, spreading of cells semaphorin-plexin signaling pathway formation of radial glial scaffolds cerebral cortex development...

Click to read more »
PLXDC2
Jumat, 2025-07-18 00:56:31

Plexin domain-containing protein 2 is a protein that in humans is encoded by the PLXDC2 gene. GRCh38: Ensembl release 89: ENSG00000120594 – Ensembl, May...

Click to read more »
SEMA4G
Kamis, 2025-07-17 01:34:49

proteins which possess a semaphoring (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Semaphorins...

Click to read more »
SEMA5A
Sabtu, 2025-10-11 22:17:54

P, Fazzari P, Gilestro GF, Barberis D, Giordano S, et al. (July 2004). "Plexin-B3 is a functional receptor for semaphorin 5A". EMBO Reports. 5 (7): 710–714...

Click to read more »
PTK7
Senin, 2025-08-18 18:18:54

neural crest cell migration) and appears to have similar functions for plexin and Flt-1 pathways. PTK7 was identified to be highly expressed in colon...

Click to read more »
GRLF1
Rabu, 2025-07-16 04:45:32

Tamagnone L (Oct 2005). "p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling" (PDF). Journal of Cell Science...

Click to read more »
SEMA3C
Sabtu, 2025-07-19 14:15:36

glioma cells express semaphorins and their receptors, neuropilins and plexins". Glia. 42 (4): 379–89. doi:10.1002/glia.10210. PMID 12730958. S2CID 45643250...

Click to read more »
Pioneer axon
Selasa, 2025-08-26 07:50:40

ideal regions. Receptor complexes for semaphorins include neuropilins and plexins. The Slit-Robo cell signaling pathway plays an important role in guiding...

Click to read more »
Axon guidance
Selasa, 2026-05-19 09:30:18

axonal repellents, and activate complexes of cell-surface receptors called plexins and neuropilins. Cell adhesion molecules (CAMs): Integral membrane proteins...

Click to read more »
Co-receptor
Senin, 2026-04-27 14:13:07

family mediates binding of VEGF in conjunction with the VEGFR1/VEGFR2 and Plexin signaling receptors, and therefore also plays a role in tumor vascular development...

Click to read more »
Chromosome 10
Selasa, 2026-03-17 14:46:52

PLEKHS1 encoding protein Pleckstrin homology domain containing S1 PLXDC2: plexin domain-containing protein 2 PRAP1: encoding protein Proline rich acidic...

Click to read more »
Multiple epidermal growth factor-like domains 8
Kamis, 2026-05-07 02:58:00

epidermal growth factor (EGF). PSI domain: domain found in plexins, semaphorins and integrins. Plexin are involved in the development of neural and epithelial...

Click to read more »
Lataisia Jones
Kamis, 2026-03-05 10:14:08

brain hemispheres. Jones took on two different research projects: studying Plexin-A1 during the postnatal development of the corpus callosum and how Tsc1...

Click to read more »
SEMA4F
Sabtu, 2025-07-19 14:15:46

negative regulation of axon extension involved in axon guidance semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...

Click to read more »
FARP2
Kamis, 2025-07-17 23:33:36

signal transduction regulation of Rho protein signal transduction semaphorin-plexin signaling pathway hair cycle process Sources:Amigo / QuickGO Orthologs Species...

Click to read more »
Catch bond
Senin, 2025-11-17 22:11:46

Reinherz EL (January 2014). "Dynamic control of beta1 integrin adhesion by the plexinD1-sema3E axis". Proceedings of the National Academy of Sciences of the United...

Click to read more »
Neuronal lineage marker
Senin, 2025-11-10 07:34:38

LINGO-1; MAP1B/MAP5; Mical-3; NAP-22; NGFR; Nestin; Netrin-1; Neuropilin; Plexin-A1; RanBPM; Semaphorin 3A; Semaphorin 3F; Semaphorin 4D; Slit2; Slit3; Staufen;...

Click to read more »
GnRH neuron
Selasa, 2025-09-30 07:06:52

regulates gonadotropin hormone-releasing hormone-1 neuronal migration through PlexinB1-Met complex". Journal of Cell Biology. 183 (3): 555–66. doi:10.1083/jcb...

Click to read more »
C-Met inhibitor
Minggu, 2026-02-22 20:44:44

Sema domain (Semaphorin-like), PSI (Plexins, Semaphorins, Integrins), IPT domain (Immunoglobulin-like, Plexins, Transcription factors) and PTK (Protein...

Click to read more »
SH3BP1
Jumat, 2025-07-18 01:19:51

negative regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway phagocytosis cell migration positive regulation of GTPase...

Click to read more »
HAND2
Jumat, 2025-11-14 03:36:32

odontogenesis of dentin-containing tooth positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis multicellular...

Click to read more »
Collapsin response mediator protein family
Senin, 2023-12-11 05:06:35

neuropilin 1 and plexin A1. While some of the other class of semaphorins directly bind to plexin receptors, Sema3A does not bind to plexin directly. Instead...

Click to read more »
Chenghua Gu
Minggu, 2026-05-03 23:02:18

M.; Kolodkin, Alex L.; Ginty, David D. (2005-01-14). "Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins". Science. 307...

Click to read more »
ARHGEF12
Selasa, 2025-07-15 10:53:08

Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG (October 2002). "B plexins activate Rho through PDZ-RhoGEF". FEBS Letters. 529 (2–3): 168–72. Bibcode:2002FEBSL...

Click to read more »
ARHGDIA
Rabu, 2025-07-16 23:30:51

transduction regulation of small GTPase mediated signal transduction semaphorin-plexin signaling pathway regulation of catalytic activity Rho protein signal transduction...

Click to read more »
Rif (GTPase)
Jumat, 2025-10-03 00:15:48

Mellor H (March 2015). "The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction". Neuroscience Letters. 590: 178–83. doi:10...

Click to read more »
SEMA4A
Sabtu, 2025-07-19 14:15:38

angiogenesis T cell differentiation involved in immune response semaphorin-plexin signaling pathway negative chemotaxis neural crest cell migration positive...

Click to read more »
ARHGEF11
Kamis, 2025-07-17 22:41:52

Driessens MH, Olivo C, Nagata K, Inagaki M, Collard JG (Oct 2002). "B plexins activate Rho through PDZ-RhoGEF". FEBS Letters. 529 (2–3): 168–72. doi:10...

Click to read more »
List of A1 genes, proteins or receptors
Selasa, 2022-03-15 01:06:59

protein, member A1 PCDHA4 Phospholipase A1 Phosphorylase kinase, alpha 1 Plexin A1 Polymerase (DNA directed), alpha 1 Potassium large conductance calcium-activated...

Click to read more »
RIT2
Kamis, 2025-12-18 19:08:08

Hartwig C, Veske A, Krejcova S, Rosenberger G, Finckh U (August 2005). "Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with...

Click to read more »
MICALL1
Jumat, 2025-07-18 00:26:05

"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...

Click to read more »
SEMA3B
Sabtu, 2025-07-19 14:15:35

axon extension involved in axon guidance chemorepulsion of axon semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...

Click to read more »
SEMA4B
Sabtu, 2025-07-19 14:15:40

347. PMID 11214970. Swiercz JM, Kuner R, Behrens J, Offermanns S (2002). "Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone...

Click to read more »
SEMA4C
Sabtu, 2025-07-19 14:15:42

closure positive regulation of stress-activated MAPK cascade semaphorin-plexin signaling pathway negative chemotaxis neural crest cell migration positive...

Click to read more »
Proteases in angiogenesis
Selasa, 2026-01-06 07:06:51

membrane-bound form by MT1-MMP (MMP-14) in tumor cells; it then interacts with plexin B1 on endothelial cells, promoting pro-angiogenic chemotaxis. Shedding of...

Click to read more »
Sortase
Rabu, 2025-11-12 05:40:07

non-canonical catalysis of the Rap GTPase activating protein domain of plexin". eLife. 2 e01279. doi:10.7554/eLife.01279. PMC 3787391. PMID 24137545....

Click to read more »
SEMA6C
Selasa, 2025-07-22 04:30:15

axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...

Click to read more »
MICAL3
Kamis, 2025-07-17 00:56:28

"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...

Click to read more »
Rnd1
Rabu, 2025-07-16 05:15:39

(Jul 2003). "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells"...

Click to read more »
WNT2
Kamis, 2025-07-17 01:59:24

mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling". Proc. Natl. Acad. Sci. U.S.A. 106 (33): 13933–8. Bibcode:2009PNAS...

Click to read more »
SEMA6A
Kamis, 2025-07-17 01:34:51

axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway Sources:Amigo / QuickGO Orthologs Species Human Mouse...

Click to read more »
MICAL1
Jumat, 2025-07-18 00:26:00

"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...

Click to read more »
Slit-Robo
Senin, 2026-06-01 01:49:15

however, full length Slit2, through interactions with semaphorin receptor plexin-A4 regulates axonal branching. Interactions between Slit and Robo in this...

Click to read more »
MAP6
Senin, 2025-10-20 08:14:16

from the hippocampus, where it is involved with the receptors Neuropilin1, Plexin D1, and VEGFR2—which together make up the tripartite Semaphorin 3E receptor...

Click to read more »
RACGAP1
Sabtu, 2025-10-04 01:39:06

1016/S1534-5807(01)00110-1. PMID 11782313. Vikis HG, Li W, Guan KL (April 2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"...

Click to read more »
RAPGEF2
Sabtu, 2025-07-19 14:07:04

Aurandt J, Vikis HG, Gutkind JS, et al. (2002). "The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide...

Click to read more »
NPTX1
Sabtu, 2025-07-19 13:43:45

PMID 17151277. Takahashi T, Strittmatter SM (2001). "Plexina1 autoinhibition by the plexin sema domain". Neuron. 29 (2): 429–39. doi:10.1016/S0896-6273(01)00216-1...

Click to read more »
Fast endophilin-mediated endocytosis
Jumat, 2026-02-06 22:51:28

Acetylcholine receptor 4 EGFR HGFR VEGFR PDGFR NGFR IGFR Tetrameric IL2R PlexinA1 ROBO1 Cholera toxins Shiga toxins Membrane scission is the process by...

Click to read more »
MICAL2
Sabtu, 2025-07-19 13:32:15

"MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion". Cell. 109 (7): 887–900. doi:10.1016/S0092-8674(02)00794-8...

Click to read more »
ARHGEF6
Rabu, 2025-10-22 10:10:35

6796-6807.2001. PMC 99857. PMID 11564864. Vikis HG, Li W, Guan KL (2002). "The plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding"...

Click to read more »
FARP1
Senin, 2025-12-22 04:41:56

of spinal motor neuron subtypes through transmembrane Semaphorin6A and PlexinA4 signaling". Neuron. 61 (3): 359–72. doi:10.1016/j.neuron.2008.12.022....

Click to read more »