Navicular cell

Micrograph showing navicular cell in extremely high magnification

Navicular cell is a boat-shaped benign epithelial cell seen in Pap smear.[1] They are seen in pregnancy (most prominently during smears taken in the second trimester),[2] second half of menstrual cycle, during menopause and in women using medroxyprogesterone acetate (depo-provera) for contraception. Navicular cells have folded edges, with a thickened outer rim of cytoplasm and an eccentric nucleus. They contain abundant glycogen in the cytoplasm, giving it a central yellow halo. The cytoplasm appears golden, refractile and granular under the microscope. In depo-provera users, the high progesterone levels result in more exfoliation of superficial squamous cells, thereby causing navicular cells to appear in Pap smear.[3]

References

  1. ^ Harshmohan (2010). Harshmohan's textbook of Pathology (5 ed.). New Delhi: Jaypee Publications. p. 280. ASIN 9351523691.
  2. ^ Sattenspiel, Edward (1950). "Vaginal cytology in normal pregnancy". Obstetrical & Gynecological Survey. 5 (6): 800. doi:10.1097/00006254-195012000-00003. Retrieved 9 December 2016.
  3. ^ EE, Volk (23 September 2000). "Cytologic findings in cervical smears in patients using intramuscular medroxyprogesterone acetate (Depo-provera) for contraception". Diagnostic Cytopathology. 23 (3): 161–4. doi:10.1002/1097-0339(200009)23:3<161::AID-DC4>3.0.CO;2-O. PMID 10945902. S2CID 39180738.
  • High magnification view
    High magnification view
  • Very high magnification view
    Very high magnification view


Stub icon

This article related to pathology is a stub. You can help Wikipedia by adding missing information.

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.