Search Results: Microsomes
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Microsome
Selasa, 2026-01-06 15:50:51laboratory; microsomes are not present in healthy, living cells. Rough (containing ribosomes) and smooth (without ribosomes) microsomes are made from...
Click to read more »S9 fraction
Sabtu, 2025-07-19 14:13:08minutes in a suitable medium; this fraction contains cytosol and microsomes." The microsomes component of the S9 fraction contain cytochrome P450 isoforms...
Click to read more »Buspirone
Kamis, 2026-06-04 14:06:20"Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes". Drug Metabolism and Disposition. 33 (4): 500–507. doi:10.1124/dmd.104...
Click to read more »Ketamine
Jumat, 2026-05-08 01:06:57CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes". Drug Metabolism and Disposition. 30 (7): 853–8. doi:10.1124/dmd.30.7...
Click to read more »LSD
Minggu, 2026-05-31 23:12:33higher than that of LSD [73–75]. In incubations of LSD with human liver microsomes and hepatocytes, 2,3-dihydroxy-LSD could be identified [71]. So far, the...
Click to read more »Simcyp
Rabu, 2026-05-13 23:09:19in vitro data generated using: Human liver microsomes Human intestinal microsomes Human kidney microsomes Human hepatocytes Recombinant CYP and UGT enzymes...
Click to read more »Ribosome
Minggu, 2026-05-17 01:02:41became apparent. To some of the participants, "microsomes" mean the ribonucleoprotein particles of the microsome fraction contaminated by other protein and...
Click to read more »Beer
Jumat, 2026-05-29 02:25:538-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes". Drug Metabolism and Disposition. 32 (2): 272–279. doi:10.1124/dmd.32...
Click to read more »Aconitine
Senin, 2026-02-09 21:50:20investigate in-depth the CYPs involved in aconitine metabolism in human liver microsomes. It has been estimated that more than 90 percent of currently available...
Click to read more »Vitamin C
Rabu, 2026-05-27 05:23:24neurotransmitters; the synthesis and catabolism of tyrosine; and the metabolism of microsomes. In nonenzymatic functions it acts as a reducing agent, donating electrons...
Click to read more »Midazolam
Jumat, 2026-05-08 22:29:54(November 2022). "High-Throughput Metabolic Soft-Spot Identification in Liver Microsomes by LC/UV/MS: Application of a Single Variable Incubation Time Approach"...
Click to read more »Mirtazapine
Rabu, 2026-06-03 16:54:23(November 2022). "High-Throughput Metabolic Soft-Spot Identification in Liver Microsomes by LC/UV/MS: Application of a Single Variable Incubation Time Approach"...
Click to read more »Psyllium
Rabu, 2026-06-03 14:44:03similarity between NADH-cytochrome b5 reductase of erythrocytes and liver microsomes". Biochimica et Biophysica Acta (BBA) - Bioenergetics. 423 (2): 293–302...
Click to read more »Albendazole
Sabtu, 2026-01-31 01:51:11responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems". Antimicrobial Agents and Chemotherapy...
Click to read more »Bupropion
Rabu, 2026-05-27 20:17:36variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes". Pharmacogenetics. 14 (4): 225–238. doi:10.1097/00008571-200404000-00002...
Click to read more »Gliclazide
Selasa, 2026-02-10 03:09:15CYP2C9 is involved in the formation of hydroxygliclazide in human liver microsomes and in a panel of recombinant human P450s in vitro. But the pharmacokinetics...
Click to read more »Glucuronide
Rabu, 2026-03-18 10:00:30S(-)-nicotine N1-glucuronide has a lower Km and higher Vmax for liver microsomes than the N(+)-nicotine N1-glucuronide, suggesting that the body has evolved...
Click to read more »Zolpidem
Senin, 2026-05-25 10:21:58adverse events, tolerance, rebound insomnia, and daytime alertness. Microsome studies indicate zolpidem is metabolized by CYP3A4 (61%) CYP2C9 (22%)...
Click to read more »Ampyrone
Jumat, 2025-10-03 00:02:23biochemical reactions producing peroxides or phenols. Ampyrone stimulates liver microsomes and is also used to measure extracellular water. By applying an ampyrone...
Click to read more »CYP2C9
Kamis, 2026-05-14 05:12:45compounds. CYP2C9 makes up about 18% of the cytochrome P450 protein in liver microsomes. The protein is mainly expressed in the liver, duodenum, and small intestine...
Click to read more »Salmonella
Jumat, 2026-05-08 21:03:17for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test". Mutation Research. 31 (6): 347–364. doi:10.1016/0165-1161(75)90046-1...
Click to read more »Freezing behavior
Senin, 2026-03-30 14:27:08A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Wilderness & Environmental Medicine. 24 (17): 1639–41. doi:10.1016/j...
Click to read more »Kent Syverud
Selasa, 2026-06-02 00:26:21Vitro Metabolism of 1,1-Dichloroethylene by Rat Hepatic Mitochondria and Microsomes (Cytochrome P-450, Chlorinated Hydrocarbon, Hepatotoxicity). Her doctoral...
Click to read more »Tetrahydrocannabinol
Kamis, 2026-06-04 21:38:29"The Potential for Pharmacokinetic Interactions Between Cannabis Proatic microsomes". Life Sciences. 80 (15): 1415–19. doi:10.1016/j.lfs.2006.12.032. PMID 17303175...
Click to read more »Progesterone carboxymethyloxime
Selasa, 2025-12-23 14:12:43respectively). In addition, it showed an in vitro terminal half-life in rat liver microsomes that was 363-fold longer than that of progesterone (half-life = 795.5 minutes...
Click to read more »13-Hydroxy-LSD
Sabtu, 2026-02-21 12:30:39higher than that of LSD [73–75]. In incubations of LSD with human liver microsomes and hepatocytes, 2,3-dihydroxy-LSD could be identified [71]. So far, the...
Click to read more »Ethylmorphine
Senin, 2026-02-02 22:02:11activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes". Toxicology Letters. 94 (2): 115–25. doi:10.1016/S0378-4274(97)00108-2...
Click to read more »Loperamide
Kamis, 2026-06-04 22:16:52metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation...
Click to read more »Fluvoxamine
Senin, 2026-05-25 12:39:54Obach RS, Ryder TF (August 2010). "Metabolism of ramelteon in human liver microsomes and correlation with the effect of fluvoxamine on ramelteon pharmacokinetics"...
Click to read more »Styrene oxide
Jumat, 2025-10-31 00:32:23were higher than the R form after exposure to styrene. In human liver microsomes, cytochrome P450-mediated styrene oxidation showed the production of more...
Click to read more »Trazodone
Senin, 2026-04-27 12:15:12electrophilic quinone-imine and epoxide intermediates in human liver microsomes and recombinant P4503A4". Chem. Biol. Interact. 155 (1–2): 10–20. Bibcode:2005CBI...
Click to read more »PNV-001
Jumat, 2026-01-23 18:17:06drug's half-life is 5.5-fold longer than that of basmisanil in human liver microsomes in vitro. It produces rapid and persistent antidepressant-like effects...
Click to read more »2-Oxo-LSD
Kamis, 2026-02-12 09:50:04were produced as major metabolites from LSD incubated with human liver microsomes (58), 2-oxo-3-HO-LSD was shown to be the main human urinary metabolite...
Click to read more »Nicotinamide adenine dinucleotide
Kamis, 2026-06-04 01:39:19nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphate". J. Biol. Chem. 262 (20): 9561–8...
Click to read more »R13 (drug)
Kamis, 2026-06-04 09:11:14tropoflavin in human liver microsomes. In contrast to R7, R13 is readily hydrolyzed into tropoflavin in human liver microsomes. R13, under the synonym and...
Click to read more »Bifenthrin
Jumat, 2025-10-03 19:07:10In Vitro Metabolism of Pyrethroid Pesticides by Rat and Human Hepatic Microsomes and Cytochrome P450 Isoforms Al-Amin (2011). "Evaluation of Bifenthrin...
Click to read more »Verruculogen
Kamis, 2025-09-04 18:09:00neurotoxic properties. It also tested positive in a Salmonella/mammalian microsome assay and was shown to be genotoxic. It is a potent blocker of calcium-activated...
Click to read more »CYP1A2
Selasa, 2026-05-05 10:22:23inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes". European Journal of Clinical Pharmacology. 57 (11): 799–804. doi:10...
Click to read more »4'-Methyl-α-pyrrolidinopropiophenone
Minggu, 2025-12-21 15:29:35olidinopropiophenone, a novel scheduled designer drug, in human liver microsomes". Drug Metabolism and Disposition. 31 (8): 979–982. doi:10.1124/dmd.31...
Click to read more »U-47700
Rabu, 2025-11-19 05:42:55"Metabolism of novel opioid agonists U-47700 and U-49900 using human liver microsomes with confirmation in authentic urine specimens from drug users". Drug...
Click to read more »Retosiban
Selasa, 2025-12-23 14:27:28intrinsic clearance in microsomes from three pre-clinical species (rat, dog, cynomolgus monkey) and low intrinsic clearance in human microsomes. It has a good...
Click to read more »Cannabidiol
Senin, 2026-05-11 00:57:44CBD mediates a decrease in clobazam metabolism. Work with human liver microsomes shows that cannabidiol inhibits CYP3A5 and CYP3A4 to some degree. In vitro...
Click to read more »Aceclofenac
Selasa, 2026-05-12 02:31:11with good permeability. It is metabolized in human hepatocytes and human microsomes to form [2-(2',6'-dichloro-4'-hydroxy- phenylamino) phenyl] acetoxyacetic...
Click to read more »Trestolone enanthate
Selasa, 2025-12-23 10:36:30D (March 2003). "Structure-activity relationship study of human liver microsomes-catalyzed hydrolysis rate of ester prodrugs of MENT by comparative molecular...
Click to read more »Ultracentrifuge
Minggu, 2025-07-27 19:39:55fine particulate fractions, such as cellular organelles (mitochondria, microsomes, ribosomes) and viruses. They can also be used for gradient separations...
Click to read more »FKBP1B
Sabtu, 2025-07-19 16:56:34ADP-ribose binds to FK506-binding protein 12.6 to release Ca2+ from islet microsomes". The Journal of Biological Chemistry. 272 (6): 3133–6. doi:10.1074/jbc...
Click to read more »4-HO-MET
Selasa, 2026-04-14 11:00:414-HO-MET has been studied. In vitro experiments using pooled human liver microsomes identified twelve metabolites. Four metabolites were detected in vivo...
Click to read more »Acetonitrile
Rabu, 2026-02-11 15:42:46[importance?] In common with other nitriles, acetonitrile can be metabolised in microsomes, especially in the liver, to produce hydrogen cyanide, as was first shown...
Click to read more »Phenanthridine
Sabtu, 2025-10-04 16:45:05metabolism of phenanthridine to phenanthridone by rat lung and liver microsomes suggests that further hydroxylation or epoxidation could enhance phenanthridone's...
Click to read more »Clonidine
Rabu, 2026-05-27 04:48:24will not be absorbed, and is thus excreted in the feces. Work with liver microsomes shows in the liver clonidine is primarily metabolized by CYP2D6 (66%)...
Click to read more »14-Hydroxy-LSD
Rabu, 2026-05-13 08:25:09minor metabolite in rhesus monkeys and humans. Studies using human liver microsomes and urine samples have confirmed its presence in humans, but in low concentrations...
Click to read more »Polychlorinated biphenyl
Rabu, 2026-05-20 04:47:145'-tetrachlorobiphenyl (PCB 52) and 3,3',4,4'-tetrachlorobiphenyl (PCB 77) by liver microsomes from four species of sea turtles". Chemical Research in Toxicology. 24...
Click to read more »Sudan I
Jumat, 2026-03-27 20:30:17urine. These metabolites are also found after oxidation with rat hepatic microsomes in vitro.[citation needed] The C-hydroxylated metabolites may be considered...
Click to read more »CYP3A4
Jumat, 2026-06-05 07:23:31involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes". British Journal of Clinical Pharmacology. 57 (3): 287–97. doi:10.1046/j...
Click to read more »Glucuronidation
Senin, 2025-05-26 05:16:15Al-Zoughool M., Talaska, G. (2006). "4-Aminobiphenyl N-glucuronidation by liver microsomes: optimization of the reaction conditions and characterization of the...
Click to read more »Membrane bound polyribosome
Sabtu, 2026-02-28 08:27:11synthesized via ribosomes with microsomes added simultaneously and with microsomes added after synthesis. In the group where microsomes were added simultaneously...
Click to read more »CYP2C19
Selasa, 2025-10-21 17:26:11respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes". Drug Metabolism and Disposition. 30 (5): 602–607. doi:10.1124/dmd.30...
Click to read more »Mometasone
Kamis, 2026-04-23 18:03:36metabolites formed is furoate 6β-hydroxymometasone. In human hepatic microsomes, the formation of these metabolites is regulated by CYP3A4. Mometasone...
Click to read more »Chloramphenicol
Senin, 2026-06-01 11:21:41inhibitor of cytochrome P450 isoforms CYP2C19 and CYP3A4 in human liver microsomes". Antimicrobial Agents and Chemotherapy. 47 (11): 3464–3469. doi:10.1128/AAC...
Click to read more »Progesterone
Kamis, 2026-06-04 06:09:23testosterone hydroxylation by cytochromes P450 2C19, 2C9, and 3A4 in human liver microsomes". Archives of Biochemistry and Biophysics. 346 (1): 161–169. doi:10.1006/abbi...
Click to read more »Ambroxol
Rabu, 2026-03-25 20:42:40predominant isoform responsible for the metabolism of ambroxol in human liver microsomes". Xenobiotica. 30 (1): 71–80. doi:10.1080/004982500237839. PMID 10659952...
Click to read more »Mescaline
Sabtu, 2026-05-30 17:08:17subject to metabolism by CYP2D6 based on in-vitro studies with human liver microsomes. Similarly, the in-vitro cytotoxicity of mescaline does not appear to...
Click to read more »Non-selective cation channel-2 family
Rabu, 2025-03-19 02:04:34Sec63 constituents of the general protein secretory systems of yeast microsomes. They are also the non-selective (NS) cation channels of the mammalian...
Click to read more »Methedrone
Kamis, 2026-02-26 16:30:54metabolites by an automated online metabolism method using human liver microsomes with subsequent identification by LC-MS(n), and metabolism of 11 cathinones"...
Click to read more »Strychnine
Senin, 2026-04-06 04:01:55Differences are due to higher rates of metabolism by male rat liver microsomes. Dogs and cats are more susceptible among domestic animals, pigs are believed...
Click to read more »Liver kidney microsomal type 1 antibody
Senin, 2024-04-22 11:14:21in type 2 AIH. It is one of the several subtypes of anti–liver-kidney microsome antibodies that are known. The frequent association of anti-LKM-1 antibodies...
Click to read more »Protoplasm
Senin, 2026-04-06 01:29:12Enchylema/Hyaloplasma (Hanstein, 1880), Kleinkörperchen or Mikrosomen (small bodies or microsomes, Hanstein, 1882), paramitome (Flemming, 1882), Idioplasma (Nägeli, 1884)...
Click to read more »Blastocystis hominis
Minggu, 2026-05-24 23:00:16H. F.; Haberland, G. (1975-09-01). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–1641. doi:10.1016/0006-2952(75)90094-5...
Click to read more »Amlodipine
Kamis, 2026-05-28 22:48:39Tang W, et al. (February 2014). "Amlodipine metabolism in human liver microsomes and roles of CYP3A4/5 in the dihydropyridine dehydrogenation". Drug Metabolism...
Click to read more »PX-1
Kamis, 2025-09-11 01:56:02cannabinoid receptor agonist PX-1 (5F-APP-PICA) via incubation with human liver microsomes and UHPLC-HRMS". Biomedical Chromatography. 34 (3) e4786. doi:10.1002/bmc...
Click to read more »Cholesterol-5,6-oxide hydrolase
Sabtu, 2026-01-24 07:02:20enzyme works equally well with either epoxide as substrate on rat liver microsomes. The ChEH is an intracellular en membranous enzyme localized mainly on...
Click to read more »DEET
Kamis, 2026-06-04 00:12:54A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochem Pharmacol. 24 (17): 1639–41. doi:10.1016/0006-2952(75)90094-5...
Click to read more »Hexahydrocannabinol
Rabu, 2026-06-03 22:48:55in the oxidative metabolism of delta 9-tetrahydrocannabinol by liver microsomes of adult female rats". Drug Metabolism and Disposition. 20 (1): 79–83...
Click to read more »Flunitrazepam
Senin, 2026-04-13 12:15:10enzyme CYP3A4 is the main enzyme in its phase 1 metabolism in human liver microsomes. Flunitrazepam is classed as a nitro-benzodiazepine. It is the fluorinated...
Click to read more »Mexazolam
Rabu, 2026-03-04 00:04:253-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors in rat liver microsomes". Drug Metabolism and Disposition. 30 (8): 904–910. doi:10.1124/dmd.30...
Click to read more »Hepatitis
Kamis, 2026-06-04 21:57:37specific to autoimmune hepatitis are the antibodies against liver kidney microsome 1 (LKM1) and soluble liver antigen (SLA). Autoimmune hepatitis can also...
Click to read more »CYP2D6
Senin, 2025-12-22 19:42:24on CYP2D6- and CYP2C9-mediated drug metabolic reactions in human liver microsomes". European Journal of Clinical Pharmacology. 57 (12): 847–851. doi:10...
Click to read more »MDMB-4en-PINACA
Rabu, 2025-12-31 18:23:00Cannabinoid with an Alkene, MDMB-4en-PINACA, by Human Hepatocytes, Human Liver Microsomes, and Human Urine and Blood". The AAPS Journal. 22 (1) 13. doi:10.1208/s12248-019-0381-3...
Click to read more »1-alkenylglycerophosphoethanolamine O-acyltransferase
Rabu, 2026-05-27 09:42:51and 1-acylglycerophosphoethanolamine in guinea-pig heart microsomes". Biochim. Biophys. Acta. 921 (2): 259–65. doi:10.1016/0005-2760(87)90026-9...
Click to read more »Mitragynine
Selasa, 2026-05-05 03:36:45has largely taken place in live rodents as well as in rodent and human microsomes. Owing to the heterogeneity of analysis and paucity of human experiments...
Click to read more »Fatty acid synthesis
Minggu, 2026-05-10 03:13:51Nugteren Uncovers enzymatic chain elongation of fatty acids in rat liver microsomes 1965 Diederik Nugteren Postulates acetyl-CoA carboxylase as the rate-limiting...
Click to read more »Sulpiride
Senin, 2026-04-20 04:36:00(January 2005). "No inhibition of cytochrome P450 activities in human liver microsomes by sulpiride, an antipsychotic drug". Biological & Pharmaceutical Bulletin...
Click to read more »Submitochondrial particle
Kamis, 2023-11-09 08:27:17biological membranes. I. Lipid oxidation in submitochondrial particles and microsomes induced by chaotropic agents". Arch Biochem Biophys. 138 (1): 73–86. doi:10...
Click to read more »5α-Pregnane-3α,11β-diol-20-one
Selasa, 2025-10-07 21:29:38sexually differentiated progesterone metabolism in adult male rat liver microsomes". J Biol Chem. 276 (7): 4604–10. doi:10.1074/jbc.M003355200. PMID 10995741...
Click to read more »NMDA receptor antagonist
Kamis, 2026-04-02 22:11:23(December 1992). "Metabolism of ketamine stereoisomers by human liver microsomes". Anesthesiology. 77 (6): 1201–7. doi:10.1097/00000542-199212000-00022...
Click to read more »Norbormide
Senin, 2025-10-13 02:24:03medium; this fraction contains cytosol and microsomes." The S9 fraction consists of two components: the microsomes component which incorporates cytochrome...
Click to read more »Ketotifen
Selasa, 2026-04-07 07:34:24norketotifen (NK), a metabolite of ketotifen. In vitro studies using human liver microsomes and hepatocytes indicate that NK is the major demethylated hepatic metabolite...
Click to read more »Selegiline
Minggu, 2026-05-17 14:33:24inhibition of CYP2B6 mediated bupropion hydroxylation in human liver microsomes by monoamine oxidase inhibitors and prediction of potential as perpetrators...
Click to read more »2-Oxo-3-hydroxy-LSD
Kamis, 2026-02-12 09:50:25higher than that of LSD [73–75]. In incubations of LSD with human liver microsomes and hepatocytes, 2,3-dihydroxy-LSD could be identified [71]. So far, the...
Click to read more »Cyclophosphamide
Jumat, 2026-03-06 15:15:25(August 1970). "Enzymatic basis of cyclophosphamide activation by hepatic microsomes of the rat". The Journal of Pharmacology and Experimental Therapeutics...
Click to read more »Daridorexant
Sabtu, 2026-02-21 08:20:52receptor antagonists. Recently, a study was carried out using human liver microsomes reported that daridorexant underwent 3 reaction; hydroxylation at the...
Click to read more »Vegetarian and vegan dog diet
Senin, 2026-02-09 21:15:03"Conversion of Essential Fatty Acids by Delta 6-Desaturase in Dog Liver Microsomes". The Journal of Nutrition. 132 (6): 1701S–1703S. doi:10.1093/jn/132.6...
Click to read more »Kapitsa–Dirac effect
Minggu, 2026-03-01 02:32:56A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–41. doi:10.1016/0006-2952(75)90094-5...
Click to read more »N-Acetylserotonin
Kamis, 2026-04-30 19:25:03oxidant damage. NAS has been shown to protect against lipid peroxidation in microsomes and mitochondria. NAS has also been reported to lower resting levels of...
Click to read more »Flubromazolam
Rabu, 2026-03-25 20:40:18metabolism from four different angles: Metabolite profiling in human liver microsomes, human hepatocytes, mice and authentic human urine samples with liquid...
Click to read more »Methylenedioxypyrovalerone
Rabu, 2026-04-15 00:00:28methylenedioxy-pyrovalerone (MDPV) in rat and human urine and human liver microsomes using GC-MS and LC-high-resolution MS and its detectability in urine by...
Click to read more »Nimodipine
Kamis, 2026-04-23 08:34:09"Enzyme kinetics and inhibition of nimodipine metabolism in human liver microsomes" (PDF). Acta Pharmacologica Sinica. 21 (8): 690–694. PMID 11501176. Archived...
Click to read more »5-MeO-MiPT
Kamis, 2026-06-04 18:32:35cytochrome P450 enzymes. In vitro experiments using pooled human liver microsomes identified seven phase I metabolites, of which five were found in vivo...
Click to read more »Tesmilifene
Jumat, 2026-04-03 22:32:23so-called "antiestrogen binding sites" (AEBS) that are present in cell microsomes as opposed to the cell nucleus. Tesmilifene was developed as a selective...
Click to read more »3',4'-Methylenedioxy-α-pyrrolidinopropiophenone
Minggu, 2026-03-01 08:25:07pha-pyrrolidinopropiophenone (MDPPP), a designer drug, in human liver microsomes". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 35...
Click to read more »HDMP-28
Jumat, 2025-12-26 11:07:46investigation of dopamine reuptake inhibitor HDMP-28 in equine liver microsomes and Cunninghamella elegans for doping control". Drug Testing and Analysis...
Click to read more »Normorphine
Kamis, 2026-06-04 00:58:23cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 33...
Click to read more »CYP2A6
Minggu, 2026-03-29 19:31:19inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes". Eur. J. Clin. Pharmacol. 57 (11): 799–804. doi:10.1007/s00228-001-0396-3...
Click to read more »Α-Naphthylthiourea
Sabtu, 2026-04-25 09:52:29ANTU ingested. α-Naphthylthiourea is metabolized by rat liver and lung microsomes to α-naphthylurea [wd] (ANU), which is essentially nontoxic to rats with...
Click to read more »21-Hydroxylase
Senin, 2026-05-11 14:49:47present in humans among primates. Steroid 21-hydroxylase is localized in microsomes of endoplasmic reticulum membranes within adrenal cortex. It is one of...
Click to read more »Atipamezole
Minggu, 2026-05-03 01:36:39"N-Glucuronidation of some 4-arylalkyl-1H-imidazoles by rat, dog, and human liver microsomes". Drug Metabolism and Disposition. 30 (3): 295–300. doi:10.1124/dmd.30...
Click to read more »4-Chloro-α-pyrrolidinovalerophenone
Kamis, 2025-09-11 01:09:35Antunes AM (2020). "Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography...
Click to read more »Long-chain-aldehyde dehydrogenase
Senin, 2026-03-30 04:25:49ALD3H2 is expressed in the human liver and has been found to localize the microsome fraction inside the cell. At least two alternative splicing isoforms of...
Click to read more »N-Desethylprotonitazene
Rabu, 2025-12-31 19:17:35vitro characterization of protonitazene metabolites, using human liver microsomes, and first application to two urines collected from death cases". Clinica...
Click to read more »NBOMe-LAD
Senin, 2026-02-16 14:27:37NBOMe-LAD showed much faster metabolism than LSD in human and rat liver microsomes in vitro. NBOMe-LAD was first described in the literature by 2022. It...
Click to read more »Christian de Duve
Selasa, 2026-03-17 10:26:49(1954). "The hexosephosphatase system. VI. Attempted fractionation of microsomes containing glucose-6-phosphatase". Bulletin de la Société de Chimie Biologique...
Click to read more »Cerivastatin
Kamis, 2026-01-01 18:39:47Kern A, et al. (March 1997). "Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome...
Click to read more »CYP2C8
Senin, 2025-06-02 12:02:39use of heterologously expressed human cytochrome P450 and human liver microsomes". Chemico-Biological Interactions. 101 (3): 175–92. Bibcode:1996CBI.....
Click to read more »Gyromitra esculenta
Minggu, 2026-05-03 22:38:02nitrosamide formation from the mushroom poison gyromitrin by rat liver microsomes". Xenobiotica. 10 (7–8): 557–64. doi:10.3109/00498258009033790. PMID 7445522...
Click to read more »Caffeine-induced anxiety disorder
Rabu, 2025-12-24 09:50:22rate at about 6 months. Cytochrome P-450, a hemeprotein, acts in liver microsomes to metabolize caffeine into dimethylxanthines, monomethylxanthines, dimethyl...
Click to read more »Rutecarpine
Senin, 2025-11-17 13:48:36a Selective Inhibitor of Cytochrome P450 1A in Mouse and Human Liver Microsomes". Drug Metabolism and Disposition. 30 (3): 349–353. doi:10.1124/dmd.30...
Click to read more »Ethyl glucuronide
Rabu, 2026-05-27 15:07:55UDP-glucuronosyltransferase catalyzed formation of ethyl glucuronide in human liver microsomes and recombinant UGTs". Forensic Science International. 153 (2–3): 109–116...
Click to read more »Drug metabolism
Kamis, 2026-05-28 13:02:43extrapolation (IVIVE) scales metabolic stability data from human liver microsomes or hepatocytes to predict human clearance. Intrinsic clearance measured...
Click to read more »4-Androstene-3,6,17-trione
Sabtu, 2026-01-03 06:42:58time-dependent irreversible binding to aromatase with human placental microsomes". Journal of Steroid Biochemistry. 28 (3): 337–344. doi:10.1016/0022-4731(87)91028-4...
Click to read more »1,8-Cineole 2-exo-monooxygenase
Selasa, 2026-03-31 21:49:49eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes". Drug Metabolism and Disposition. 29 (2): 200–5. PMID 11159812. Miyazawa...
Click to read more »Hexobarbital
Jumat, 2025-03-21 22:45:52hydroxylation and hexobarbital-dependent hydrogen peroxide production in hepatic microsomes of guinea pig, rat and rabbit". Naunyn-Schmiedeberg's Archives of Pharmacology...
Click to read more »Timolol
Kamis, 2026-05-28 06:32:34Mäenpää J, Pelkonen O (July 2007). "Timolol metabolism in human liver microsomes is mediated principally by CYP2D6". Drug Metabolism and Disposition. 35...
Click to read more »Tibolone
Kamis, 2026-02-26 04:18:31been found to be transformed into 7α-methylestradiol by human placental microsomes in vitro. Also in accordance, considerably disproportionate formation...
Click to read more »Reboxetine
Senin, 2026-05-25 18:05:02individual enantiomers of the antidepressant agent reboxetine in human liver microsomes". Drug Metabolism and Disposition. 27 (11): 1334–40. doi:10.1016/S0090-9556(24)14936-7...
Click to read more »History of RNA biology
Selasa, 2026-02-10 20:47:19showed that radioactive amino acids were found to be associated with "microsomes" (later redefined as ribosomes) very rapidly after administration, and...
Click to read more »List of designer drugs
Jumat, 2026-05-15 17:47:44"Metabolism of novel opioid agonists U-47700 and U-49900 using human liver microsomes with confirmation in authentic urine specimens from drug users". Drug...
Click to read more »4-Methylethcathinone
Minggu, 2025-09-28 10:34:04substance 4-methyl-N-ethyl-cathinone (4-MEC) in human urine and pooled liver microsomes by GC-MS and LC-HR-MS/MS techniques and of its detectability by GC-MS...
Click to read more »12-Hydroxyheptadecatrienoic acid
Minggu, 2024-09-29 13:03:30It was identified as a product of arachidonic acid metabolism made by microsomes isolated from sheep seminal vesicle glands and by intact human platelets...
Click to read more »Aflatoxin
Rabu, 2026-05-20 04:45:48Coulombe RA (August 2011). "Metabolism of aflatoxin B1 in turkey liver microsomes: the relative roles of cytochromes P450 1A5 and 3A37". Toxicology and...
Click to read more »Trospium chloride
Selasa, 2026-04-07 08:18:08to the elimination of trospium. Data taken from in vitro human liver microsomes investigating the inhibitory effect of trospium on seven cytochrome P450...
Click to read more »Statin
Sabtu, 2026-05-30 22:22:47Kern A, et al. (March 1997). "Metabolism of cerivastatin by human liver microsomes in vitro. Characterization of primary metabolic pathways and of cytochrome...
Click to read more »Differential centrifugation
Selasa, 2026-06-02 00:19:48centrifuge Mitochondria, chloroplasts, lysosomes, peroxisomes Cytosol, microsomes (known as post mitochondrial supernatant) Supernatant of previous row...
Click to read more »2C-EF
Kamis, 2026-01-22 10:29:04Raul JS, Kintz P (2025). "Metabolic profiling of 2C-EF in human liver microsomes: Identification of major metabolites and biotransformation pathways"....
Click to read more »5-MeO-DiPT
Minggu, 2026-05-24 11:15:14metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes". Biochem Pharmacol. 71 (9): 1377–1385...
Click to read more »Omega hydroxy acid
Minggu, 2025-12-07 16:17:20Omega hydroxy fatty acids also occur in animals. Cytochrome P450 (CYP450) microsome ω-hydroxylases such as CYP4A11, CYP4A22, CYP4F2, and CYP4F3 in humans...
Click to read more »2C-EF-FLY
Jumat, 2026-03-13 16:12:37Raul JS, Kintz P (2026). "Metabolic profiling of 2C-EF in human liver microsomes: Identification of major metabolites and biotransformation pathways"....
Click to read more »Ricobendazole
Selasa, 2026-04-14 01:03:30flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes". British Journal of Clinical Pharmacology. 49 (4): 313–322. doi:10.1046/j...
Click to read more »Ledol
Senin, 2025-10-06 20:23:15such as parthenolide, showed the sesquiterpenes reacting to human liver microsomes. This demonstrates the reactivity with the liver's CYP3A4 enzyme. Through...
Click to read more »Benzylone
Minggu, 2026-03-01 10:21:04metabolites by an automated online metabolism method using human liver microsomes with subsequent identification by LC-MS(n), and metabolism of 11 cathinones"...
Click to read more »Carvone
Selasa, 2026-03-10 19:14:49"Stereoselective metabolism of the monoterpene carvone by rat and human liver microsomes". Journal of Pharmacy and Pharmacology. 52 (2): 191–197. doi:10.1211/0022357001773841...
Click to read more »Mutagen
Minggu, 2026-05-31 04:30:52(December 1975). "Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals". Proceedings of the National Academy of...
Click to read more »Ethidium bromide
Senin, 2026-06-01 15:08:45mutagenicity and ethidium bromide mutagenicity in the Salmonella/mammalian microsome reverse mutation assay (Ames test)". Mutation Research. 439 (1): 37–47...
Click to read more »Cyclooxygenase
Jumat, 2026-05-29 15:18:15membrane anchor fixes the proteins into the endoplasmic reticulum (ER) and microsome membrane. COX is a common target for anti-inflammatory drugs. The most...
Click to read more »Cedrol
Kamis, 2025-08-14 01:24:02β-cedrene, and thujopsene on cytochrome P450 enzyme activities in human liver microsomes". Journal of Toxicology and Environmental Health. Part A. 77 (22–24):...
Click to read more »Prenylation
Minggu, 2025-11-30 13:16:10Swiezewska, E.; Dallner, G. (1998). "Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase". Archives...
Click to read more »Ames test
Minggu, 2025-12-14 01:43:44mutagens. Mortelmans K, Zeiger E (November 2000). "The Ames Salmonella/microsome mutagenicity assay". Mutation Research. 455 (1–2): 29–60. Bibcode:2000MRFMM...
Click to read more »Phenprocoumon
Kamis, 2026-01-22 21:25:56mass-spectrometric identification of two novel metabolites in human plasma and liver microsomes". Analytical and Bioanalytical Chemistry. 383 (6): 909–17. doi:10.1007/s00216-005-0113-7...
Click to read more »List of Greek and Latin roots in English/P–Z
Kamis, 2025-06-19 11:02:45hexasomy, isodisomic, isodisomy, macrosomia, metasomatic, metasomatism, microsome, microsomia, monosome, monosomic, monosomy, pentasomic, pentasomy, plasmosome...
Click to read more »Albendazole monooxygenase
Minggu, 2026-03-22 21:59:45albendazole by a cytochrome P450-independent monooxygenase from rat liver microsomes". Vet. Res. Commun. 10 (4): 317–324. doi:10.1007/BF02213995. PMID 3739217...
Click to read more »NADPH—hemoprotein reductase
Senin, 2026-03-02 09:39:01of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components". J. Biol. Chem. 244 (13): 3714–21. doi:10...
Click to read more »Levofloxacin
Jumat, 2026-05-29 01:25:44inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes". Acta Pharmacol. Sin. 29 (12): 1507–14. doi:10.1111/j.1745-7254.2008...
Click to read more »Trans fat
Senin, 2026-05-18 22:34:53fatty acids on the delta 5, delta 6 and delta 9 desaturases of rat liver microsomes in vivo". Acta Biologica et Medica Germanica. 40 (12): 1699–1705. PMID 7345825...
Click to read more »Monoacylglycerol lipase
Kamis, 2025-07-17 00:58:37comparative characterization of six serine hydrolases from rat liver microsomes". Arch. Biochem. Biophys. 200 (2): 547–59. doi:10.1016/0003-9861(80)90386-0...
Click to read more »Norpethidine
Minggu, 2026-01-04 11:46:27responsible for the in vitro N-demethylation of meperidine in human liver microsomes". Drug Metabolism and Disposition: The Biological Fate of Chemicals. 32...
Click to read more »Trans-cinnamate 4-monooxygenase
Kamis, 2026-04-02 20:34:46EE, Rowell J (1974). "The 4-hydroxylation of cinnamic acid by sorghum microsomes and the requirement for cytochrome P-450". J. Biol. Chem. 249 (16): 5019–26...
Click to read more »National Anti-Slavery Standard
Rabu, 2026-06-03 02:44:50H. F.; Haberland, G. (1975-09-01). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–1641. ISSN 1873-2968. PMID 10...
Click to read more »Dehydratase
Sabtu, 2025-07-19 12:35:24"Evidence that beta-hydroxyacyl-CoA dehydrase purified from rat liver microsomes is of peroxisomal origin". The Biochemical Journal. 287 ( Pt 1) (Pt 1):...
Click to read more »Phosmet
Minggu, 2026-05-17 03:12:42through an in vitro study using rat liver microsomes, for which C-phosmet is incubated with said microsomes, and confirming metabolization of compound...
Click to read more »7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
Rabu, 2025-07-30 16:33:04the other donor. It was purified and characterized from rabbit liver microsomes in 1992 and was cloned and sequenced in 1996. Its structure was 39% similar...
Click to read more »Stearoyl-CoA 9-desaturase
Senin, 2026-04-06 09:12:19mechanism associated with fatty acid desaturation catalyzed by liver microsomes". Biochim. Biophys. Acta. 128 (1): 13–27. doi:10.1016/0926-6593(66)90137-8...
Click to read more »Lars Ernster
Kamis, 2026-03-05 13:30:58colleague, fellow-European and competitor Edward Slater. In Mitochondria and Microsomes (C.P. Lee, G. Schatz and G. Dallner, eds.) Addison-Wesley Publishing Co...
Click to read more »1-Lysophosphatidylcholine
Jumat, 2026-03-20 21:24:442-acylglycerophosphocholine O-acyltransferase, an enzyme purified in liver microsomes, catalyzes specifically the acylation of 1-lysoPC with acyl-CoA to create...
Click to read more »Inner mitochondrial membrane
Sabtu, 2025-12-27 03:13:01outer and inner membranes from pig heart mitochondria. Comparison with microsomes". Biochim. Biophys. Acta. 419 (2): 271–84. doi:10.1016/0005-2736(76)90353-9...
Click to read more »Sterol-C5-desaturase-like
Jumat, 2026-01-23 17:38:26"Markedly inhibited 7-dehydrocholesterol-delta 7-reductase activity in liver microsomes from Smith-Lemli-Opitz homozygotes". J. Clin. Invest. 96 (4): 1779–85...
Click to read more »Plant seed peroxygenase
Minggu, 2025-07-27 14:12:37"Purification and characterization of solubilized peroxygenase from microsomes of pea seeds". The Journal of Biological Chemistry. 254 (17): 8427–33...
Click to read more »1,4-lactonase
Kamis, 2025-07-17 21:49:22"Purification and properties of an enzyme in human blood and rat liver microsomes catalyzing the formation and hydrolysis of γ-lactones. I. Tissue localization...
Click to read more »Pazopanib
Rabu, 2025-12-24 20:02:39and CYP2C8. Metabolites identified in tests with human liver cells and microsomes include various hydroxyl derivatives and possibly a carboxylic acid. Only...
Click to read more »Thiopropamine
Sabtu, 2026-02-21 15:17:57cytochromes P450: studies on substrate specificity and regioselectivity with microsomes and purified CYP2C subfamily isozymes". The Journal of Toxicological Sciences...
Click to read more »Frances Milton Trollope
Selasa, 2026-05-19 06:49:29Haberland, G. (1 September 1975). "Digitoxin metabolism by rat liver microsomes" (PDF). Biochemical Pharmacology. 24 (17): 1639–1641. doi:10.1016/0006-2952(75)90094-5...
Click to read more »Mequitazine
Kamis, 2025-12-25 23:10:55antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes" (PDF). The Journal of Pharmacology and Experimental Therapeutics. 284...
Click to read more »5'-nucleotidase
Rabu, 2025-11-26 17:25:01Segal HL, Brenner BM (February 1960). "5′-Nucleotidase of rat liver microsomes". The Journal of Biological Chemistry. 235 (2): 471–4. doi:10.1016/S0021-9258(18)69548-1...
Click to read more »16β,17α-Epiestriol
Minggu, 2026-03-08 14:05:251972. pp. 233–. ISBN 978-0-08-086626-0. Ryō Satō; Ryūichi Katō (1982). Microsomes, drug oxidations, and drug toxicity. Japan Scientific Societies Press...
Click to read more »Vesicle (biology and chemistry)
Senin, 2026-04-27 11:11:12contact sites Membrane nanotube Membrane vesicle trafficking Micelle Microsome Protocell Spitzenkörper, a structure of many small vesicles found in fungal...
Click to read more »CYP3A5
Rabu, 2026-04-01 09:00:31pseudogene. CYP3A4/3A5 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway...
Click to read more »Salvador Moncada
Sabtu, 2025-12-13 09:39:20M.; Samuelsson, B. (1976). "Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides". Nature...
Click to read more »Safinamide
Selasa, 2026-04-07 07:34:24acid (NW-1689), and the glucuronide of the latter. In tests with liver microsomes, dealkylation seemed to be mediated by CYP3A4, but other CYP enzymes appear...
Click to read more »Calcifediol
Senin, 2025-09-29 03:06:3225-hydroxylase reaction is mostly due to the actions of CYP2R1, present in microsomes, although other enzymes such as mitochondrial CYP27A1 can contribute....
Click to read more »Linoleoyl-CoA desaturase
Selasa, 2026-03-17 15:22:41and partial characterization of linoleoyl-CoA desaturase from rat liver microsomes". Arch. Biochem. Biophys. 206 (1): 21–28. doi:10.1016/0003-9861(81)90061-8...
Click to read more »Ceftaroline fosamil
Selasa, 2026-02-10 03:42:57been conducted with ceftaroline fosamil. In vitro studies in human liver microsomes indicated that neither ceftaroline fosamil nor ceftaroline inhibits the...
Click to read more »Pharmacoepigenetics
Selasa, 2025-02-11 09:54:18with DNA methylation and positively with histone acetylation in mouse microsome extracts. CXCR4 is a protein that acts as a coreceptor for the entry of...
Click to read more »UGT2B17
Kamis, 2025-07-17 01:54:20UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes". Pharmacogenet. Genomics. 15 (11): 769–78. doi:10.1097/01.fpc.0000175596...
Click to read more »Ectopic ureter
Kamis, 2025-07-31 23:40:23A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–41. doi:10.1016/0006-2952(75)90094-5...
Click to read more »Carl Benda
Jumat, 2025-08-08 16:35:22bodies, and are identical to at least a portion of the already known cell microsomes, but differ from Altmann's and Ehrlich's granulations. I would like to...
Click to read more »MORT (long non-coding RNA)
Rabu, 2025-03-19 18:20:58MORT is enriched in the 100,000 g fraction, which contains polysomes, microsomes, endoplasmic reticulum, and the plasma membrane. Evidence is mounting...
Click to read more »UGT2B7
Minggu, 2026-05-24 23:15:20relationship with the main UGT polymorphisms in a bank of human liver microsomes". Drug Metabolism and Disposition. 38 (1): 40–5. doi:10.1124/dmd.109.029546...
Click to read more »4'-Methoxy-α-pyrrolidinopropiophenone
Jumat, 2026-04-10 01:11:444'-methoxy-alpha-pyrrolidinopropiophenone (MOPPP), a designer drug, in human liver microsomes". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 33...
Click to read more »Indoxyl sulfate
Sabtu, 2026-05-30 21:51:32hydroxylation in the liver; in vitro experiments with rat and human liver microsomes suggest that the CYP450 enzyme CYP2E1 hydroxylates indole into indoxyl...
Click to read more »Dibromodichloromethane
Minggu, 2025-11-16 12:36:03Haberland, G. (1 September 1975). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–1641. doi:10.1002/anie.201704074...
Click to read more »Prazepam
Senin, 2025-09-01 12:25:12"Stereoselective metabolism of prazepam and halazepam by human liver microsomes". Drug Metabolism and Disposition. 19 (3): 637–642. doi:10.1016/S0090-9556(25)07201-0...
Click to read more »Enniatin
Senin, 2026-05-18 10:59:12demonstrated this in an in vitro study using rat, dog, and human liver microsomes. With the use of selective chemical inhibitors, they determined that CYP3A...
Click to read more »R7 (drug)
Minggu, 2026-02-22 13:09:47animals, it showed almost no conversion into tropoflavin in human liver microsomes. Tropoflavin, a naturally occurring flavonoid, was found to act as an...
Click to read more »SYBR Green I
Jumat, 2025-09-12 03:57:38mutagenicity and ethidium bromide mutagenicity in the Salmonella/mammalian microsome reverse mutation assay (Ames test)". Mutation Research. 439 (1): 37–47...
Click to read more »Didesmethylsibutramine
Rabu, 2025-09-24 06:44:59lobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes". Drug Metabolism and Disposition. 36 (8): 1679–1688. doi:10.1124/dmd...
Click to read more »SNX8
Jumat, 2025-10-03 09:07:36DNA-triggered SNX8-mediated association of MITA and VPS34, and its intracellular transport pathway from RE to perinuclear microsomes via Golgi apparatus....
Click to read more »Tuberculocide
Kamis, 2025-09-04 20:47:54"Metabolism of ebracteolata compound B studied in vitro with human liver microsomes, HepG2 cells, and recombinant human enzymes". Drug Metabolism and Disposition:...
Click to read more »Normethandrone
Senin, 2026-02-02 14:18:05of Metabolites of three Anabolic Androgenic Steroids, by Human Liver Microsomes (Master's thesis thesis). Institutt for Bioteknologi. Archived from the...
Click to read more »Aldrin
Selasa, 2026-05-05 20:15:43(March 1965). "Epoxidation of aldrin, isodrin, and heptachlor by rat liver microsomes". Biochemical Pharmacology. 14 (3): 375–377. doi:10.1016/0006-2952(65)90210-8...
Click to read more »Unspecific monooxygenase
Sabtu, 2024-06-22 11:38:04biochemistry of aromatic amines. 3. Enzymic hydroxylation by rat-liver microsomes". Biochem. J. 66 (1): 73–8. doi:10.1042/bj0660073. PMC 1199967. PMID 13426111...
Click to read more »Oxidosqualene cyclase
Sabtu, 2025-07-19 23:35:34reactions that form the rings. Oxidosqualene is located in the cell’s microsome membranes where it can easily harvest its hydrophobic substrate and turn...
Click to read more »Eicosanoid
Selasa, 2025-11-25 21:45:56to 16,17-dihydroxy-eicosatrienoic acid (16,17-DiETrE. Cytochrome P450 microsome ω hydroxylases: CYP4A11, CYP4A22, CYP4F2, and CYP4F3 metabolize arachidonic...
Click to read more »TRALA-12
Sabtu, 2026-05-02 10:03:09TRALA-12 shows dramatically faster metabolism than LSD in human liver microsomes in vitro. Whereas about 75% remained in the case of LSD following incubation...
Click to read more »Frameshift mutation
Selasa, 2026-06-02 04:52:12HF; Haberland, G (1 September 1975). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–41. doi:10.1016/0006-2952(75)90094-5...
Click to read more »Epidemic dropsy
Selasa, 2025-10-28 09:11:32damage of lipids in various hepatic sub-cellular fractions including microsomes and mitochondria of rats. The damage in hepatic microsomal membrane causes...
Click to read more »Methionyl aminopeptidase
Selasa, 2024-01-02 16:31:21(1985). "Methionine aminopeptidase associated with liver mitochondria and microsomes". Int. J. Biochem. 17 (12): 1285–1291. doi:10.1016/0020-711x(85)90049-7...
Click to read more »Xenobiotic metabolism
Kamis, 2026-06-04 06:55:44PMID 16748905. Omura T, Sato R (1 April 1962). "A new cytochrome in liver microsomes". The Journal of Biological Chemistry. 237 (4): 1375–1376. doi:10...
Click to read more »12-Hydroxy-LSD
Senin, 2026-04-13 08:55:09hydroxylated metabolites from lysergic acid diethylamide by rat liver microsomes". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 10...
Click to read more »List of selective estrogen receptor modulators
Rabu, 2025-12-24 09:38:27derivative specific for the antiestrogen binding site found in rat liver microsomes". Biochem. Biophys. Res. Commun. 123 (2): 724–8. doi:10.1016/0006-291x(84)90289-4...
Click to read more »Flavin-containing monooxygenase 3
Rabu, 2026-03-25 22:16:21monooxygenase mediated metabolism of psychoactive drugs by human brain microsomes". Brain Res. 672 (1–2): 276–80. doi:10.1016/0006-8993(94)01135-5. PMID 7749747...
Click to read more »Methiopropamine
Minggu, 2026-02-22 15:18:55cytochromes P450: studies on substrate specificity and regioselectivity with microsomes and purified CYP2C subfamily isozymes". The Journal of Toxicological Sciences...
Click to read more »8-Prenylnaringenin
Minggu, 2025-12-14 05:46:308-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes". Drug Metabolism and Disposition. 32 (2): 272–9. doi:10.1124/dmd.32.2...
Click to read more »14-Hydroxygelsenicine
Kamis, 2026-04-16 06:53:42effects. A study looking into the metabolism of HGE was performed on liver microsomes. The major metabolic pathways for HGE are hydroxylation, reduction, N-de-methyl...
Click to read more »C-5 sterol desaturase
Minggu, 2026-05-10 08:34:10it is a transmembrane protein. C5SD activity has been demonstrated in microsomes from rat tissue, implying that rat enzyme localizes to the endoplasmic...
Click to read more »ACSL1
Selasa, 2026-02-24 05:40:46and very-long-chain-acyl-CoA synthetase activities in peroxisomes and microsomes from rat liver. An enzymological study". European Journal of Biochemistry...
Click to read more »1-acylglycerophosphocholine O-acyltransferase
Sabtu, 2023-08-26 19:22:121-acylglycerophosphorylcholine acyltransferase resolved from rat liver microsomes". Eur. J. Biochem. 81 (3): 433–41. doi:10.1111/j.1432-1033.1977.tb11968...
Click to read more »CYP4A11
Kamis, 2025-12-18 10:13:01of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes". Archives of Biochemistry and Biophysics. 335 (1): 219–226. doi:10.1006/abbi...
Click to read more »15-Hydroxyeicosatetraenoic acid
Kamis, 2025-10-09 17:41:52be formed as result of the metabolism of arachidonic acid by cellular microsomes or as a result of arachidonic acid auto-oxidation. Similar to 15(S)-HpETEs...
Click to read more »Octopus minor
Jumat, 2025-10-17 03:40:47Benthe; G, Haberland (1975-09-01). "Digitoxin Metabolism by Rat Liver Microsomes". Biochemical Pharmacology. 24 (17): 1639–41. doi:10.1016/0006-2952(75)90094-5...
Click to read more »CYP2B6
Jumat, 2026-01-16 04:11:30and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes". Drug Metabolism and Disposition: The Biological Fate of Chemicals. 25...
Click to read more »SRD5A2
Rabu, 2023-11-08 10:21:55"Inhibition of androgen synthesis in human testicular and prostatic microsomes and in male rats by novel steroidal compounds". Endocrinology. 140 (6):...
Click to read more »Carboxylesterase
Minggu, 2024-10-20 16:55:55characterization of five lipolytic enzymes (carboxylesterases) from rat liver microsomes". Arch. Biochem. Biophys. 234 (2): 612–21. doi:10.1016/0003-9861(84)90311-4...
Click to read more »Anti-LKM antibody
Minggu, 2026-02-15 16:12:252002.34734 Ma Y, Okamoto M, Thomas MG, et al. Antibodies to liver kidney microsome type 1 in children with autoimmune hepatitis. Journal of Hepatology. 2002;36(2):254–259...
Click to read more »Pyrethroid hydrolase
Kamis, 2026-02-19 19:00:24purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes". The Journal of Biological Chemistry. 279 (28): 29863–9. doi:10.1074/jbc...
Click to read more »Phosphatidylcholine—dolichol O-acyltransferase
Sabtu, 2025-08-02 20:51:13Keenan RW, Kruczek ME (1976). "The esterification of dolichol by rat liver microsomes". Biochemistry. 15 (7): 1586–91. doi:10.1021/bi00652a032. PMID 4095. Radominska-Pyrek...
Click to read more »List of steroid abbreviations
Kamis, 2024-04-04 05:56:363 beta-hydroxysteroid dehydrogenase activity in tissue fragments and microsomes from human term placenta: kinetic analysis and inhibition by steroids"...
Click to read more »Pesticide resistance
Minggu, 2026-04-19 03:55:00aryldialkylphosphatase and mixed microsomal oxidases (oxidases expressed within microsomes). Alternatively, the number and/or sensitivity of biochemical receptors...
Click to read more »Cholate—CoA ligase
Kamis, 2026-02-19 16:50:38(March 1956). "The enzymic activation of cholic acid by guinea-pig-liver microsomes". The Biochemical Journal. 62 (3): 427–33. doi:10.1042/bj0620427. PMC 1215932...
Click to read more »Resibufogenin
Sabtu, 2025-10-04 08:10:00rate, orthotunos, and death. Resibufogenin is metabolized in the liver microsomes. The metabolic reactions of RBG are hydroxylation, dihydroxylation, dehydrogenation...
Click to read more »Estradiol 6beta-monooxygenase
Rabu, 2026-04-15 22:50:186beta-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes". J. Am. Chem. Soc. 79 (4): 1004–1005. Bibcode:1957JAChS..79R1004M. doi:10...
Click to read more »1-acylglycerol-3-phosphate O-acyltransferase
Sabtu, 2023-08-26 19:22:10acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes". Eur. J. Biochem. 38 (1): 25–31. doi:10.1111/j.1432-1033.1973.tb03028...
Click to read more »Cysteine-S-conjugate N-acetyltransferase
Sabtu, 2025-08-02 19:48:31WB (1982). "Cysteine S-conjugate N-acetyltransferase from rat kidney microsomes". Mol. Pharmacol. 21 (2): 444–8. doi:10.1016/S0026-895X(25)14616-6. PMID 6892478...
Click to read more »Olumbe Bassir
Senin, 2026-05-25 03:37:53- Oxidative metabolism of aflatoxin B1 by mammalian liver slices and microsomes. 1979 - The uncoupling effect of N-(phosphonomethyl) glycine on isolated...
Click to read more »Ryanodine receptor 2
Senin, 2025-08-11 12:51:27Olivey HE, et al. (March 2001). "FKBP binding characteristics of cardiac microsomes from diverse vertebrates". Biochemical and Biophysical Research Communications...
Click to read more »Xylan
Sabtu, 2026-03-28 15:30:18immuno-purified xylan synthase activity from etiolated wheat (Triticum aestivum) microsomes. Jiang et al. (2016) reported a xylan synthase complex (XSC) from wheat...
Click to read more »Omega oxidation
Selasa, 2026-01-20 16:59:43signaling molecules. In humans, a subset of Cytochrome P450 (CYP450) microsome-bound ω-hydroxylases (termed Cytochrome P450 omega hydroxylases) metabolize...
Click to read more »Albert Claude
Rabu, 2026-03-18 02:23:50He also discovered cytoplasmic granules full of RNA and named them "microsomes", which were later renamed ribosomes, the protein synthesizing machineries...
Click to read more »Alpha-fetoprotein
Kamis, 2026-03-19 19:36:48HF, Haberland G (September 1975). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–1641. doi:10.1016/0006-2952(75)90094-5...
Click to read more »Nicolas Bazan
Jumat, 2026-03-27 23:33:25microsomes. Biochim Biophys Acta 796:11-19, 1984 Reddy TS, Bazan NG: Kinetic properties of arachidonoyl coenzyme A synthetase in rat brain microsomes...
Click to read more »CYP2E1
Rabu, 2026-05-27 05:19:53oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians". The Journal of Pharmacology and Experimental...
Click to read more »Hyodeoxycholic acid
Rabu, 2025-09-17 12:52:05alpha-glucuronidation of hyodeoxycholic acid by human liver, kidney and small bowel microsomes". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 921...
Click to read more »NFKBIE
Sabtu, 2025-07-19 13:41:18(2002). "Effects of TCDD upon IkappaB and IKK subunits localized in microsomes by proteomics". Arch. Biochem. Biophys. 406 (2): 153–64. doi:10...
Click to read more »3-Bromomethcathinone
Senin, 2026-05-25 15:34:583-fluoromethcathinone: studies on their metabolism in rat urine and human liver microsomes using GC-MS and LC-high-resolution MS and their detectability in urine"...
Click to read more »Valerylfentanyl
Jumat, 2026-04-03 05:03:04LE (June 2022). "The metabolism of valerylfentanyl using human liver microsomes and zebrafish larvae". Drug Testing and Analysis. 14 (6): 1116–1129. doi:10...
Click to read more »Sean Ekins
Minggu, 2026-03-08 14:59:32the vinca alkaloid a-aminophosphonate derivative S12363 by human liver microsomes". Br J Clin Pharmacol. 36 (2): 165P–166P. doi:10.1111/j.1365-2125.1993...
Click to read more »Methamnetamine
Minggu, 2026-04-05 18:19:58"Characterization of in vitro phase I metabolites of methamnetamine in human liver microsomes by liquid chromatography-quadrupole time-of-flight mass spectrometry"...
Click to read more »Dhurrin
Kamis, 2025-03-20 20:28:19grain. In vitro biosynthesis of dhurrin has been constructed in both microsomes recovered from Sorghum bicolor seedlings and in micelles. Mammalian intestines...
Click to read more »Cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase
Rabu, 2025-12-10 23:28:43of a 3 β-hydroxy-delta 5-C27-steroid oxidoreductase from rabbit liver microsomes". J. Biol. Chem. 256 (7): 3376–80. doi:10.1016/S0021-9258(19)69618-3....
Click to read more »UGT1A4
Sabtu, 2025-07-19 14:39:49"Characterization of nicotine and cotinine N-glucuronidations in human liver microsomes". Drug Metab. Dispos. 30 (12): 1484–90. doi:10.1124/dmd.30.12.1484. PMID 12433823...
Click to read more »Thomas Wallace Donnelly
Senin, 2026-03-02 12:35:10Haberland, G. (September 1, 1975). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–1641. ISSN 1873-2968. PMID 10...
Click to read more »CYP3A
Jumat, 2025-10-17 20:18:102-hydroxylation of 1,4-cineole, a monoterpene cyclic ether, by rat and human liver microsomes". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 31...
Click to read more »Benzoxazinone biosynthesis
Selasa, 2026-02-10 19:42:40the pathway occur in the endoplasmic reticulum, also referred to as the microsomes in cell fractionation experiments, and are carried by proteins encoded...
Click to read more »Glossary of cellular and molecular biology (M–Z)
Selasa, 2026-03-31 02:50:16variable number tandem repeat (VNTR) DNA, along with longer minisatellites. microsome A small intracellular vesicle derived from fragments of endoplasmic reticulum...
Click to read more »Regucalcin
Rabu, 2025-10-22 09:42:10membrane), microsomes (endoplasmic reticulum) and mitochondria of many cells. Regucalcin is localized in the cytoplasm, mitochondria, microsomes and nucleus...
Click to read more »Alkenylglycerophosphoethanolamine hydrolase
Sabtu, 2023-08-26 20:03:521-(1-alkenyl)-sn-glycero-3-phosphoethanolamine (lysoplasmalogen) by rat liver microsomes". Hoppe-Seyler's Z. Physiol. Chem. 362 (4): 445–52. doi:10.1515/bchm2...
Click to read more »Antalarmin
Kamis, 2026-01-22 22:39:13demonstrated low oral bioavailability, and in vitro studies using human liver microsomes predicted high hepatic clearance, deeming the compound unsuitable for...
Click to read more »Dolichylphosphate-mannose phosphodiesterase
Sabtu, 2023-08-26 20:55:17a novel mannosylphosphodolichol phosphodiesterase from chicken liver microsomes". Eur. J. Biochem. 170 (1–2): 363–8. doi:10.1111/j.1432-1033.1987.tb13708...
Click to read more »Retinol O-fatty-acyltransferase
Minggu, 2026-01-18 14:58:51Helgerud P, Petersen LB, Norum KR (1983). "Retinol esterification by microsomes from the mucosa of human small intestine. Evidence for acyl-Coenzyme A...
Click to read more »EG-018
Selasa, 2025-12-30 19:55:33vitro metabolic profiling of synthetic cannabinoids by pooled human liver microsomes, cytochrome P450 isoenzymes, and Cunninghamella elegans and their detection...
Click to read more »Camazepam
Minggu, 2025-09-28 22:45:35derivatives and enantioselective metabolism of camazepam by human liver microsomes". Journal of Chromatography A. 666 (1–2): 249–257. doi:10.1016/0021-9673(94)80387-0...
Click to read more »Microcystin-LR
Minggu, 2025-12-21 23:54:29of Microcystis aeruginosa peptide toxin and interactions with hepatic microsomes in mice Pharmacol. Toxicol., 60(3), 187-191. Kondo, F., Matsumoto, H....
Click to read more »Galactosyldiacylglycerol alpha-2,3-sialyltransferase
Minggu, 2025-08-03 17:33:35"Biosynthesis in vitro of sialosylgalactosyldiacylglycerol by mouse brain microsomes". J. Biol. Chem. 256 (23): 12306–9. doi:10.1016/S0021-9258(18)43271-1...
Click to read more »Terminal deoxynucleotidyl transferase
Senin, 2026-04-20 03:13:00HF, Haberland G (September 1975). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–41. doi:10.1016/0006-2952(75)90094-5...
Click to read more »EAM-2201
Sabtu, 2025-12-27 03:27:56metabolism of a novel synthetic cannabinoid, EAM-2201, in human liver microsomes and human recombinant cytochrome P450s". Journal of Pharmaceutical and...
Click to read more »Pharmacodynamics of spironolactone
Selasa, 2025-12-23 06:16:24inhibit 17 beta-hydroxysteroid dehydrogenase activity in human placental microsomes". J. Med. Chem. 38 (22): 4518–28. doi:10.1021/jm00022a018. PMID 7473580...
Click to read more »Cytochrome P450 (individual enzymes)
Senin, 2026-04-06 17:32:49Coulombe RA (August 2011). "Metabolism of aflatoxin B1 in turkey liver microsomes: the relative roles of cytochromes P450 1A5 and 3A37". Toxicology and...
Click to read more »All-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific)
Senin, 2025-08-18 18:01:01of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes". The Journal of Biological Chemistry. 268 (31): 23081–6. doi:10...
Click to read more »CYP4F2
Senin, 2026-02-09 03:28:11key enzymes responsible for this conversion in human liver microsomes and enteric microsomes. CYP4F2 is also involved in the metabolism of fingolimod,...
Click to read more »Chlorfenvinphos
Minggu, 2026-05-17 02:05:50chlorfenvinphos in humans is accomplished by the enzyme cytochrome P450 in liver microsomes. This enzyme facilitates oxidative dealkylation of the compound to acetaldehyde...
Click to read more »Enoxacin
Selasa, 2025-12-23 22:44:47antimicrobial enoxacin and derivatives on theophylline metabolism by rat liver microsomes". Antimicrobial Agents and Chemotherapy. 40 (8): 1875–1880. doi:10.1128/AAC...
Click to read more »Perovskite nanocrystal
Kamis, 2026-04-09 06:37:12A, Benthe HF, Haberland G (1975). "Digitoxin metabolism by rat liver microsomes" (PDF). Biochem Pharmacol. 24 (17): 1639–1641. doi:10.1016/0006-2952(75)90094-5...
Click to read more »CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase
Minggu, 2024-10-13 04:48:06phosphatidylglycerol and phosphatidylglycerol phosphate by rabbit lung microsomes". Biochim. Biophys. Acta. 710 (3): 377–90. doi:10.1016/0005-2760(82)90121-7...
Click to read more »Amitraz
Rabu, 2026-04-08 09:57:57synthesis of prostaglandin E2 from arachidonic acid by bovine seminal vesicle microsomes. In a dose of 5 to 80 mg/kg body weight, given intraperitoneally to rats...
Click to read more »Α-Pyrrolidinopentiothiophenone
Senin, 2026-06-01 08:50:18ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome". Biomedical Chromatography. 28 (6): 831–838. doi:10.1002/bmc.3155. PMID 24861751...
Click to read more »Gyromitrin
Senin, 2026-03-16 22:17:00nitrosamide formation from the mushroom poison gyromitrin by rat liver microsomes". Xenobiotica. 10 (7–8): 557–64. doi:10.3109/00498258009033790. PMID 7445522...
Click to read more »Armando J. Parodi
Senin, 2026-03-23 19:47:01research that was involved with the incubation of dolichol-P-Glc using liver microsomes to transfer glucose to a dolichol-P-P-linked glycan known as...
Click to read more »4-Methyl-N,N-dimethylcathinone
Senin, 2026-04-20 10:23:25Alexandra M. M. (2020). "Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography...
Click to read more »Dale Sanders
Jumat, 2025-07-18 02:58:31R.; Sanders, Dale (1996). "Pharmacology of Ca2+ release from red beet microsomes suggests the presence of ryanodine receptor homologs in higher plants"...
Click to read more »Polyacrylamide gel electrophoresis
Jumat, 2026-05-15 15:53:08mutagenicity and ethidium bromide mutagenicity in the Salmonella/mammalian microsome reverse mutation assay (Ames test)". Mutat. Res. 439 (1): 37–47. Bibcode:1999MRGTE...
Click to read more »Taurochenodeoxycholate 6α-hydroxylase
Selasa, 2026-03-31 22:38:15taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of...
Click to read more »Cytochrome P450 reductase
Jumat, 2026-01-30 06:27:55of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components". The Journal of Biological Chemistry. 244 (13):...
Click to read more »ERAP1
Selasa, 2026-06-02 07:41:46similarities. The co-elution of ERAP1 and ERAP2 was detected through microsome fractionation, in the 230 kDa fraction, suggesting the formation of heterodimers...
Click to read more »Desulfosarcina
Selasa, 2026-02-10 09:37:23Benthe, H.F.; Haberland, G. (1975). "Digitoxin metabolism by rat liver microsomes" (PDF). Biochemical Pharmacology. 24 (17): 1639–1641. doi:10.1016/0006-2952(75)90094-5...
Click to read more »HGSNAT
Kamis, 2025-07-17 00:31:27"Localisation of acetyl-CoA: alpha-glucosaminide N-acetyltransferase in microsomes and lysosomes of rat liver". Hoppe-Seyler's Z. Physiol. Chem. 362 (9):...
Click to read more »Coumestrol
Sabtu, 2026-02-21 14:53:45"Inhibition of 3a-hydroxysteoid dehydogenase (3a-HSD) activity of human lung microsomes by genistein, daidzein, coumestrol and C18-, C19- and C21 hydroxysteroids...
Click to read more »Polyprenol reductase
Sabtu, 2025-07-26 12:12:18dehydrodolichol is catalyzed by NADPH-dependent reductase localized in microsomes of rat liver". The Journal of Biological Chemistry. 268 (14): 10109–13...
Click to read more »EPHX1
Selasa, 2025-09-16 04:58:47activity. However, their functional effect was not confirmed in human liver microsomes. Due to the EPHX1 role in metabolism of procarcinogens and existence of...
Click to read more »ACSL4
Kamis, 2025-10-02 02:32:01Klemisch W (2000). "In vitro metabolism of acitretin by human liver microsomes: evidence of an acitretinoyl-coenzyme A thioester conjugate in the transesterification...
Click to read more »Dolichyl β-D-glucosyl phosphate
Minggu, 2026-05-31 23:32:12B, Jeanloz RW (1977). "Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked...
Click to read more »C286
Selasa, 2025-09-30 03:50:28enzymes (1A2, 2C9, 2C19, 2D6, 3A4), and shows very high stability in human microsomes, It was found to possess a good oral bioavailability in both rat (80%)...
Click to read more »Harry Gelboin
Sabtu, 2026-05-09 04:48:42and carcinogens are metabolized by enzymes in small lipid vesicles (microsomes) in the liver. He demonstrated that microsomal enzymes convert certain...
Click to read more »Tropinesterase
Minggu, 2025-07-06 12:22:21purification and characterization of atropine esterase from rabbit liver microsomes (author's transl)]". Hoppe-Seyler's Z. Physiol. Chem. 355 (5): 529–42...
Click to read more »5-Hydroxyeicosanoid dehydrogenase
Rabu, 2026-04-15 00:00:19distribution have been limited to examining the ability of cells or cell microsomes to make 5-oxo-ETE from 5(S)-HETE. A wide variety of cell types possess...
Click to read more »Alkylglycerol monooxygenase
Senin, 2023-12-11 08:44:38partial characterization of alkylglycerol monooxygenase from rat liver microsomes". Eur. J. Biochem. 132 (1): 23–7. doi:10.1111/j.1432-1033.1983.tb07320...
Click to read more »Citreoviridin
Sabtu, 2024-10-26 07:21:34kinetic constants of acetylcholinesterase and ATPase in synaptosomes and microsomes from rat brain". Toxicon. 19 (4): 555–62. Bibcode:1981Txcn...19..555D...
Click to read more »Sterol 14-demethylase
Kamis, 2026-04-09 20:17:09agents with cytochrome P-45014DM purified from Saccharomyces cerevisiae microsomes". Biochemical Pharmacology. 36 (2): 229–35. doi:10.1016/0006-2952(87)90694-0...
Click to read more »SEC16B
Kamis, 2025-07-31 20:12:43RGPR-p117 is present in the plasma membranes, cytoplasm, mitochondria, microsomes and nucleus of the cells. Cytoplasm RGPR-p117 is translocated to nucleus...
Click to read more »7-Dehydrocholesterol reductase
Sabtu, 2026-04-18 15:26:43"Markedly inhibited 7-dehydrocholesterol-delta 7-reductase activity in liver microsomes from Smith-Lemli-Opitz homozygotes". The Journal of Clinical Investigation...
Click to read more »Mutagenesis
Kamis, 2026-05-28 14:30:00OCLC 216723160. Omura, T.; Sato, R. (1962). "A new cytochrome in liver microsomes". The Journal of Biological Chemistry. 237 (4): 1375–1376. doi:10...
Click to read more »Polysulfobetaine
Senin, 2026-04-13 23:40:16H. F.; Haberland, G. (1975-09-01). "Digitoxin metabolism by rat liver microsomes". Biochemical Pharmacology. 24 (17): 1639–1641. doi:10.1016/0006-2952(75)90094-5...
Click to read more »Ceramide phosphoethanolamine synthase
Senin, 2025-11-10 11:35:49(1986). "Sphingomyelin and ceramide-phosphoethanolamine synthesis by microsomes and plasma membranes from rat liver and brain". J. Lipid Res. 27 (3):...
Click to read more »2,6-Dimethoxybenzoquinone
Rabu, 2025-02-19 21:10:13608-620. Non-mutagenicity of some wood-related compounds in the bacterial/microsome plate incorporation and microsuspension assays. Mohtashamipur, E., Norpoth...
Click to read more »List of Greek and Latin roots in English/S
Kamis, 2026-02-26 09:52:43hexasomy, isodisomic, isodisomy, macrosomia, metasomatic, metasomatism, microsome, microsomia, monosome, monosomic, monosomy, pentasomic, pentasomy, plasmosome...
Click to read more »5α-Dihydronormethandrone
Selasa, 2025-07-29 02:26:24of Metabolites of three Anabolic Androgenic Steroids, by Human Liver Microsomes (Master's thesis, Institutt for bioteknologi). https://brage.bibsys...
Click to read more »Methylcholanthrene
Selasa, 2025-11-04 21:01:26competitively, reducing the estrogen expression. MC is metabolized by rat liver microsomes into oxygenated forms which alkylate DNA. These oxygenated metabolites...
Click to read more »Steroid Delta-isomerase
Rabu, 2026-04-08 17:31:341979). "Activation of delta5-3-ketosteroid isomerase of bovine adrenal microsomes by serum albumins". Biochemical and Biophysical Research Communications...
Click to read more »Auxotrophy
Jumat, 2026-03-13 21:28:27for detecting carcinogens and mutagens with the salmonella/mammalian-microsome mutagenicity test". Mutation Research/Environmental Mutagenesis and Related...
Click to read more »5-MeO-DALT
Rabu, 2026-03-18 15:50:10Psychoactive Substances Furanylfentanyl, TFMPP, and 5-MeO-DALT in Human Liver Microsomes". Current Analytical Chemistry. 18 (9): 1003–1016. doi:10.2174/1573411018666220603100033...
Click to read more »FADS2
Sabtu, 2026-04-04 00:07:08dietary supplementation can reverse the aging influence on rat liver microsome delta 6-desaturase activity". Biochimica et Biophysica Acta (BBA) - Lipids...
Click to read more »Phulchand Prithvi Raj
Rabu, 2026-05-06 02:52:17children: a respiratory emergency Oxidation drug metabolism in human liver microsomes Techniques for fiberoptic laryngoscope in anesthesia The site of action...
Click to read more »Bile salt-dependent lipase
Selasa, 2025-07-01 19:47:21"Association of bile-salt-dependent lipase with membranes of human pancreatic microsomes". Eur. J. Biochem. 233 (1): 209–18. doi:10.1111/j.1432-1033.1995.209_1...
Click to read more »Dolichyl-phosphate alpha-N-acetylglucosaminyltransferase
Minggu, 2025-08-03 15:35:47"The biosynthesis of a N,N'-diacetylchitobiose containing lipid by liver microsomes. A probable dolichol pyrophosphate derivative". Biochem. Biophys. Res...
Click to read more »Discovery and development of angiotensin receptor blockers
Senin, 2025-09-22 10:26:00Effects of Angiotensin Receptor Blockers on CYP2C9 Activity in Human Liver Microsomes", Drug Metabolism and Pharmacokinetics, 22 (4): 267–275, doi:10.2133/dmpk...
Click to read more »David D. Sabatini
Rabu, 2026-01-07 23:24:44in rat liver cell fractions. II. Location of the polypeptides in rough microsomes. J Cell Biol 45, 146-157. Blobel G. and Sabatini, D.D., (1970).Controlled...
Click to read more »Dolichol kinase
Kamis, 2025-12-18 14:32:09"Properties of a dolichol phosphokinase activity associated with rat liver microsomes". Can. J. Biochem. 58 (10): 1051–6. doi:10.1139/o80-142. PMID 6257336...
Click to read more »Glycerophospholipid acyltransferase (CoA-dependent)
Sabtu, 2025-08-02 20:16:21(1979). "Transfer of arachidonic acid between phospholipids in rat liver microsomes". Biochem. Biophys. Res. Commun. 91 (4): 1399–405. Bibcode:1979BBRC.....
Click to read more »15α-Hydroxyestradiol
Kamis, 2026-06-04 16:03:49metabolism of 17beta-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5". J. Pharmacol...
Click to read more »Alkylglycerophosphoethanolamine phosphodiesterase
Minggu, 2024-09-22 23:21:15lysophospholipase D pathway in the metabolism of ether-linked lipids in brain microsomes". J. Biol. Chem. 249 (6): 1742–6. doi:10.1016/S0021-9258(19)42850-0. PMID 4855486...
Click to read more »Leukotriene-E4 20-monooxygenase
Minggu, 2026-03-22 23:30:231987). "Omega-oxidation of cysteine-containing leukotrienes by rat-liver microsomes. Isolation and characterization of omega-hydroxy and omega-carboxy metabolites...
Click to read more »Richard Tecwyn Williams
Selasa, 2025-12-30 23:49:47spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes". The Biochemical Journal. 96 (2): 390–398. doi:10.1042/bj0960390. PMC 1207052...
Click to read more »PDSS1
Senin, 2025-11-03 12:54:01of the side chain of ubiquinone:trans-prenyltransferase in rat liver microsomes". J. Biol. Chem. 268 (31): 23081–6. doi:10.1016/S0021-9258(19)49428-3...
Click to read more »Androgen backdoor pathway
Senin, 2026-04-13 20:06:21"Metabolic pathways for androstanediol formation in immature rat testis microsomes". primary. Biochimica et Biophysica Acta (BBA) - General Subjects. 924...
Click to read more »Maree Smith
Rabu, 2026-04-08 06:52:28Stability of Two Novel Endomorphin-2 Analogs, CYX-5 and CYX-6, in Rat Liver Microsomes, European Journal of Drug Metabolism and Pharmacokinetics, 2023. Nonopioid...
Click to read more »N-Acylethanolamine
Rabu, 2025-10-01 01:08:27properties to NAE-binding proteins in intact tobacco microsomes, compared to non-intact microsomes. In addition to this, antagonists of mammalian CB receptors...
Click to read more »Dolichyl-phosphate beta-glucosyltransferase
Minggu, 2026-05-31 23:20:49B, Jeanloz RW (1977). "Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked...
Click to read more »Quinine 3-monooxygenase
Senin, 2026-03-30 22:41:20P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450". J. Pharmacol. Exp. Ther...
Click to read more »Epelsiban
Minggu, 2026-02-01 04:00:27cytochrome P450 (Cyp450) enzyme profile of 3 using intrinsic clearance in microsomes to drive the improvements in the later’s pharmacokinetic profile lead...
Click to read more »Azinphos-methyl
Minggu, 2026-05-17 01:59:52bioactivation of four organophosphorothioate pesticides by human liver microsomes". Toxicol Appl Pharmacol. 186 (3): 143–154. Bibcode:2003ToxAP.186..143B...
Click to read more »5F-AMB
Sabtu, 2025-01-11 19:30:19new synthetic cannabinoids AMB and 5F-AMB by human hepatocyte and liver microsome incubations and high-resolution mass spectrometry". Rapid Communications...
Click to read more »Fluparoxan
Rabu, 2025-12-24 13:26:29hydroxylated metabolites were identified after incubation with rat liver microsomes (S9) or in rat urine following oral dosing. The compound was well tolerated...
Click to read more »Cytochrome b5, type A
Senin, 2025-08-18 11:35:22(1971). "Amino acid sequences of tryptic peptides of cytochromes b5 from microsomes of human, monkey, porcine, and chicken liver". J. Biol. Chem. 246 (6):...
Click to read more »Mary Locke Petermann
Senin, 2025-12-29 07:34:09a pool of particles containing nucleic acids and proteins he termed "microsomes." Petermann found that these particles contained roughly equal amounts...
Click to read more »12-Hydroxyeicosatetraenoic acid
Senin, 2026-06-01 12:32:18acids studied with human recombinant enzymes and with human and rat liver microsomes". The Journal of Pharmacology and Experimental Therapeutics. 284 (1):...
Click to read more »Chuan-Pu Lee
Kamis, 2026-03-05 04:46:59of her subjects and collaborators. She also co-edited Mitochondria and microsomes (1981), a collection of essays in honor of Lars Ernstner; and co-edited...
Click to read more »9-Hydroxyoctadecadienoic acid
Selasa, 2025-09-30 15:56:05stereoisomer predominates, for instance by a R/S ratio of 80%/20% in human liver microsomes. In cells and tissues, the cytochrome enzymes concurrently metabolize...
Click to read more »Icosanoyl-CoA synthase
Sabtu, 2025-08-02 20:28:16of C18 CoA and C20 CoA elongases from Allium porrum L. epidermal-cell microsomes". FEBS Lett. 187 (2): 314–320. Bibcode:1985FEBSL.187..314L. doi:10...
Click to read more »FICD
Kamis, 2026-05-21 18:22:07have been shown for dFic through in vitro translation in the presence of microsomes, which indicated N-glycosylation at site Asn288. While FICD (HYPE in humans)...
Click to read more »5-Oxo-eicosatetraenoic acid
Sabtu, 2025-10-04 03:05:4914Z-eicosatetraenoic acid (5(S)-HETE); and (d) the oxidation of 5(S)-HETE by a microsome-bound nicotinamide adenine dinucleotide phosphate (NADP+)-dependent dehydrogenase...
Click to read more »Nicotinic acid adenine dinucleotide phosphate
Senin, 2025-10-13 09:58:57Nucleotide Metabolites Stimulate Calcium Release from Sea Urchin Egg Microsomes Desensitized to Inositol Trisphosphate". The Journal of Biological Chemistry...
Click to read more »(C6)-CP 47,497
Senin, 2025-12-29 22:06:26vitro metabolites of CP 47,497, a synthetic cannabinoid, in human liver microsomes by LC-MS/MS". Journal of Forensic Sciences. 58 (1): 195–199. doi:10.1111/j...
Click to read more »Cyclotriol
Selasa, 2025-12-23 13:13:11examination for the induction of gene mutations using the Ames Salmonella/microsome test and the HGPRT test in V79 cells". Environmental and Molecular Mutagenesis...
Click to read more »2-acylglycerol-3-phosphate O-acyltransferase
Sabtu, 2023-08-26 19:25:05acyltransferase and 1-acylglycerophosphorylcholine acyltransferase from rat-liver microsomes". Eur. J. Biochem. 38 (1): 25–31. doi:10.1111/j.1432-1033.1973.tb03028...
Click to read more »ALOXE3
Minggu, 2026-05-10 08:04:29acids studied with human recombinant enzymes and with human and rat liver microsomes". The Journal of Pharmacology and Experimental Therapeutics. 284 (1):...
Click to read more »Arnold Martin Katz
Rabu, 2025-12-24 20:26:00protein kinase stimulation of calcium uptake by canine cardiac microsomes". J Mol Cell Cardiol. 4 (6): 673–680. doi:10.1016/0022-2828(72)90120-4...
Click to read more »13-Hydroxyoctadecadienoic acid
Senin, 2026-02-23 13:45:58by a R/S ratio of 80%/20% for both 13-HODE and 9-HODE in human liver microsomes. Oxidative stress in cells and tissues produces Free radical and singlet...
Click to read more »Flavin-containing monooxygenase
Selasa, 2026-06-02 06:41:15flavin-containing monooxygenases. Comparison of human liver and kidney microsomes and mammalian enzymes". Biochemical Pharmacology. 60 (1): 7–17. doi:10...
Click to read more »20-Hydroxyeicosatetraenoic acid
Rabu, 2025-09-24 23:28:04particularly those of the breast. A subset of cytochrome P450 (CYP450) microsome-bound ω-hydroxylases, the cytochrome P450 omega hydroxylases, metabolize...
Click to read more »Calanolide A
Sabtu, 2025-12-27 02:52:462017). "Metabolism of F18, a Derivative of Calanolide A, in Human Liver Microsomes and Cytosol". Frontiers in Pharmacology. 8 (479): 479. doi:10.3389/fphar...
Click to read more »PSMA4
Selasa, 2025-10-21 03:58:50et al. (June 1996). "Subpopulations of proteasomes in rat liver nuclei, microsomes and cytosol". The Biochemical Journal. 316 ( Pt 2) (Pt 2): 401–407. doi:10...
Click to read more »Francesco De Lorenzo
Selasa, 2026-04-07 19:19:54F. "Evaluation of the Mutagenic of Coded Compounds in the Salmonella/Microsome Test. In: Evolution of short-term tests for carcinogens International...
Click to read more »Phosphatidylcholine desaturase
Minggu, 2024-02-11 18:28:00biosynthesis of linoleate from oleoyl-CoA via oleoyl-phosphatidylcholine in microsomes of developing safflower seeds". European Journal of Biochemistry. 90 (2):...
Click to read more »Index of biophysics articles
Selasa, 2025-09-02 20:37:54Metachronal rhythm Methylhopane Microbial ecology Microbial fuel cell Microsome Model lipid bilayer Moens–Korteweg equation Mohammad-Nabi Sarbolouki Molecular...
Click to read more »Cyclodiol
Selasa, 2025-12-23 13:14:55examination for the induction of gene mutations using the Ames Salmonella/microsome test and the HGPRT test in V79 cells". Environmental and Molecular Mutagenesis...
Click to read more »List of MeSH codes (A11)
Senin, 2026-03-30 11:38:37514.700.500 – nuclear lamina MeSH A11.284.835.540 – microsomes MeSH A11.284.835.540.541 – microsomes, liver MeSH A11.284.835.626 – mitochondria MeSH A11...
Click to read more »Epoxygenase
Minggu, 2026-05-10 10:43:59epoxyeicosatrienoic acids (EETs) as defined using recombinant CYPs in an in vitro microsome assay. Most of these CYPs preferentially form 14,15-ETE, somewhat lower...
Click to read more »Phosphatidylcholine—retinol O-acyltransferase
Sabtu, 2025-08-02 20:52:02(1989). "Lecithin:retinol acyltransferase in retinal pigment epithelial microsomes". J. Biol. Chem. 264 (15): 8636–40. doi:10.1016/S0021-9258(18)81839-7...
Click to read more »25-hydroxycholesterol 7α-hydroxylase
Senin, 2023-11-27 21:14:02(September 1994). "7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylase"...
Click to read more »Cholesterol 7alpha-monooxygenase
Jumat, 2025-07-04 17:39:07and characterization of cholesterol 7 alpha-hydroxylase from rat liver microsomes". J. Biol. Chem. 262 (16): 7646–50. doi:10.1016/S0021-9258(18)47615-6...
Click to read more »Neville Colman
Rabu, 2025-01-22 04:26:29Victor (1979). "Non-mutagenicity of gossypol in the salmonella/mammalian-microsome plate assay". Environmental Mutagenesis. 1 (4): 315–320. doi:10.1002/em...
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