InGeneron

InGeneron Inc.
Company type
Private[1]
IndustryHealth Technology, Biotechnology
Founded2006
Headquarters
Houston, Texas
,
United States
Area served
USA, Europe, Middle East
Key people
Angelo Moesslang[2]
(CEO)
Ron Stubbers[3]
(President)
Eckhard Alt
(Founder, Chairman of the Board)
ProductsRegenerative cell separation and diagnostic tools
Number of employees
32
Divisions
  • Wound Care
  • Aesthetics & Reconstruction
  • Orthopedics and Spine
  • Cardiovascular
  • Animal Health
Subsidiaries
Websitewww.ingeneron.com

InGeneron Inc. is a private multinational medical device and biotechnology company headquartered in Houston, Texas, United States, and with European headquarters in Munich, Germany. InGeneron develops, manufactures, licenses and sells regenerative cell separation and diagnostics tools. InGeneron's technologies enable the preparation of adipose-derived regenerative cells (ADRC)[6] that contain progenitor and stem cells in humans and animals for autologous use.[7]

History

InGeneron was founded in 2006, through a recapitalization of aDEPtas, Inc. in Houston, Texas with the focus on translating fundamental research in the regenerative medicine field into clinical practice. Over 40 peer-reviewed studies have been published by InGeneron's team in collaboration with various renowned academic facilities.[8] In 2010, the fully owned subsidiary InGeneron GmbH in Munich was founded to serve as its European headquarters.[9] In 2015, InGeneron Equine GmbH[10] was founded in Germany, which focuses on treating orthopedic indications of sports horses. In 2015, the German-based stem cell banking company eticur) was acquired with the idea of supporting eticur) with scientific evidence from InGeneron's laboratory.[11] In 2012, InGeneron's technology was also used to treat a Malayan tiger at the Houston zoo.[12][13] In March 2017, InGeneron raised $20 million in Series D funding from Sanford Health.[14]

Products

InGeneron's preprogrammed and heatable Tissue Processing Unit
A complete InGeneron SmartGraft 200 system with Mr. Squeezy for fat grafting

InGeneron develops and manufactures biomedical equipment that is designed to fit into the workflow of an operating physician for the easy recovery of regenerative cells from the adipose tissue.[15]

An efficient point-of-care processing system that isolates regenerative cells from adipose tissue has been developed. This system relies on a proprietary enzyme blend and centrifuge technology to isolate and prepare regenerative cells with high yield from adipose tissue within one hour after extraction.[16]

Initial results in the veterinary space show that possible treatment areas include orthopedic injuries, osteoarthritis, incontinence, soft tissue reconstruction and non-healing wounds in animals.[17]

Transpose RT System

Consisting of the disposables for processing and the Tissue Processing Unit, the Transpose RT System is InGeneron's system that allows for point-of-care preparation of regenerative cells. The collected tissue is processed with the InGeneron Tissue Processing Unit, which is a semi-automated, heatable centrifuge that is developed to process tissue prior to stem cell extraction and uses proprietary agitation to assist in the separation of the regenerative cells.

This system is used in conjunction with the Matrase enzyme that ensures a high yield of regenerative cells. The proprietary enzyme is designed to quickly and gently release from adipose tissue the adult regenerative cells.

Accessories

For the extraction and processing, InGeneron provides:

  • Lipoaspiration Collection Kit
  • Transpose® RT Lipoaspirate Processing System
  • Transpose® RT Tissue Processing System
  • SmartGraft 30 and SmartGraft 200 System for fat grafting procedures

For veterinarian use, InGeneron provides:

  • Lipoaspirate Collection Kit
  • ARC® Lipoaspirate Processing System (Quad-Pack of the Transpose RT Lipoaspirate Processing System, adapted for veterinary use)
  • ARC® Tissue Processing System (Quad-Pack of the Transpose RT Tissue Processing System, adapted for veterinary use)
  • ARC® Platelet-Rich-Plasma System

Regulatory

The InGeneron Processing Unit as well as disposable packs such as the Lipoaspiration Collection Kit, Transpose RT Lipoaspirate Processing Kit and the SmartGraft Systems are CE marked and meet the requirements of the applicable EC directive.[18]

The Matrase enzymatic agent is manufactured mammalian origin free and in strict compliance with cGMP guidelines.[19]

The SmartGraft 30 and SmartGraft 200 System have 510(k) approval in the US market.[20][21]

References

  1. ^ About InGeneron Archived 2016-04-27 at the Wayback Machine retrieved on April 18, 2016
  2. ^ InGeneron Appoints Angelo Moesslang as Chief Executive Officer retrieved October 20, 2017
  3. ^ InGeneron Announces Changes in Management Team retrieved February 20, 2017
  4. ^ InGeneron Equine Imprint retrieved April 18, 2016
  5. ^ Eticur) Press Release retrieved October 29, 2015
  6. ^ "Why use adipose-derived stem cells? | Ingeneron". www.ingeneron.com. Retrieved 2016-07-25.[permanent dead link]
  7. ^ "Ingeneron Inc: Company Profile". Bloomberg. Retrieved 2016-07-12.
  8. ^ "Literature References | Ingeneron". ingeneron.principlepointdev.com. Archived from the original on 2016-07-04. Retrieved 2016-07-12.
  9. ^ "Handelsregisterauszug von InGeneron GmbH (HRB 185925)". www.online-handelsregister.de. Archived from the original on 2016-12-02. Retrieved 2016-08-11.
  10. ^ "Facebook - InGeneron Equine". www.facebook.com. Retrieved 2016-07-25.
  11. ^ "eticur) ist ab sofort Teil eines weltweiten Stammzell-Kompetenznetzwerks". www.eticur.de. Retrieved 2016-07-12.
  12. ^ Big cats get special treatment at the Houston Zoo retrieved April 18, 2016
  13. ^ Malayan Tiger and Black Leopard Undergo Treatment for Arthritis Archived 2016-09-13 at the Wayback Machine retrieved April 18, 2016
  14. ^ "InGeneron Raises $20M in Series D Funding". FinSMEs. 2017-03-06. Retrieved 2017-03-10.
  15. ^ "Human Health Products | Ingeneron". www.ingeneron.com. Retrieved 2016-07-12.
  16. ^ "Human Health Products | Ingeneron". www.ingeneron.com. Retrieved 2016-07-12.
  17. ^ InGeneron Treatment Areas Archived 2016-10-11 at the Wayback Machine retrieved September 12, 2016
  18. ^ "ISAKOS: 2013 Congress in Toronto, Canada: Abstract View". www.isakos.com. Retrieved 2016-07-19.
  19. ^ "Research Lab Products | Ingeneron". www.ingeneron.com. Archived from the original on 2016-09-20. Retrieved 2016-09-19.
  20. ^ "Department of Health and Human Services - Notification SmartGraft 30" (PDF).[dead link]
  21. ^ "Department of Health and Human Services - Notification SmartGraft 200" (PDF).

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