DOSEN PROFIL LENGKAP

GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene. The protein encoded by this gene is a member of the IRS1-like multisubstrate...

"tonic" activity of PI3K/Akt axis via upregulation of an adaptor protein GAB1, and this also allows B cells to survive targeted therapy with BCR inhibitors...

to FAK. YopH also binds the p85 subunit of phosphoinositide 3-kinase, the Gab1, the Gab2 adapter proteins, and the Vav guanine nucleotide exchange factor...

protein-2 (Grb2) along with a docking protein called Grb2-associated Binder-1 (GAB1). Subsequently, phosphatidylinositol-3 kinase (PI3K) is activated, resulting...

scaffolding protein Gab1 Tyr 1349 and Tyr 1356 of the multisubstrate docking site are both involved in the interaction with GAB1, SRC, and SHC, while...

can also support survival of malignant B cells by inducing the activity of GAB1-PI3K axis and mTORC2-pAKT axis. FOXO1 activation plays a role in cell cycle...

Epidermal growth factor receptor, Erythropoietin receptor, FRS2, Fas ligand, GAB1, GAB2, Glycoprotein 130, Granulocyte colony-stimulating factor receptor,...

cloned GAB2 by searching DNA database for protein with sequence homology to GAB1. GAB2 is a large multi-site docking protein (LMD) of about 100kD that has...

contain an AHRR-NCOA2 fusion gene in 60% to 80% of cases and a GTF2I-NCOA2 or GAB1-ABL1 fusion gene in rare cases. Cellular angiofibroma is usually a small...

specific adaptors to the plasma membrane. For example, β1c integrin recruits Gab1/Shp2 and presents Shp2 to IGF1R, resulting in dephosphorylation of the receptor...

EXOC8, FAM109A, FAM109B, FARP1, FARP2, FGD1, FGD2, FGD3, FGD4, FGD5, FGD6, GAB1, GAB2, GAB3, GAB4, GRB10, GRB14, GRB7, IRS1, IRS2, IRS4, ITK, ITSN1, ITSN2...

family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–53. doi:10...

BCAR1, CBLB, CD117, CD28, CD7, CENTG1, CBL, EPHA2, EPOR, ERBB3, EZR, FCGR2A, GAB1, GAB2, Grb2, HRAS, IRS1 IRS2, IL1R1, JAK2, KHDRBS1, LTK, LAT, LCP2, PIK3CD...

activity of SHP-2 in LEOPARD syndrome: consequences for PI3K binding on Gab1". FEBS Lett. 580 (10): 2477–82. Bibcode:2006FEBSL.580.2477H. doi:10.1016/j...

pathways. MAP3K3 has been shown to interact with [SQSTM1/p62],: BRCA1, AKT. GAB1, MAP2K5, and YWHAE. Two SNPs in the MAP3K3 gene were found as candidates...

FRS2-alpha and PLC-gamma. FRS2-alpha acts as a scaffold protein to hold GAB1 and GRB2 which then proteins bind to SHP2 and SOS. These several proteins...

family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–34653. doi:10...

factor receptor, Eukaryotic translation elongation factor 1 alpha 1, FLT1, GAB1, GIT1, Grb2, HER2/neu, IRS2, ITK, KHDRBS1, Linker of activated T cells, Lymphocyte...

chimpanzee was found to have a lentivirus (SIVcpzGAB1) that was closely related to HIV-1. The genome of SIVcpzGAB1 had an accessory gene that was so far unique...

HGNC:24861; Q9BUM1 5957 G6PD HGNC:4057; P11413 5958 GAA HGNC:4065; P10253 5959 GAB1 HGNC:4066; Q13480 5960 GAB2 HGNC:14458; Q9UQC2 5961 GAB3 HGNC:17515; Q8WWW8...

gene, CD117, CD31, CEACAM1, Epidermal growth factor receptor, Erk FRS2, GAB1, GAB2, GAB3, Glycoprotein 130, Grb2, Growth hormone receptor, HoxA10, Insulin...

PIGU Identifiers Aliases PIGU, CDC91L1, GAB1, phosphatidylinositol glycan anchor biosynthesis class U, GPIBD21, NEDBSS External IDs OMIM: 608528; MGI:...

factor receptor, Eukaryotic translation elongation factor 1 alpha 1, FLT1, GAB1, GIT1, Grb2, HER2/neu, IRS2, ITK, KHDRBS1, Linker of activated T cells, Lymphocyte...

domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif". Oncogene. 20 (9):...

with: Abl gene, BCAR1, BCR gene, CBLB, CD117, CD34, Cbl gene, Dock2, EPOR, GAB1, GAB2, INPP5D, MAP4K1, MAP4K5, NEDD9, PIK3R2, Paxillin RAPGEF1, RICS, STAT5A...

family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–53. doi:10...

family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200...

Angiotensinogen expression Regenerate itself by hepatocyte mitosis Via STAT and Gab1: RAS/MAPK, PLC/IP3 and PI3K/FAK Cell growth, proliferation, survival, invasion...

domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif". Oncogene. 20 (9):...

family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200...

Funaki M, Gotoh N, et al. (2001). "Unique phosphorylation mechanism of Gab1 using PI 3-kinase as an adaptor protein". Biochem. Biophys. Res. Commun....

PMID 26546043. Paliouras GN, Naujokas MA, Park M (June 2009). "Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor"...

family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200...

interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Transcript...

fusion gene, rare AFST tumor cases have also been shown to be associated with GAB1-ABL1, GTF2I-NCOA2, NCOA2-ETV4, ETV4-AHRR, and NAB2-STAT6 fusion genes. The...

family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200...

factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL". The Journal of Biological Chemistry. 275 (15):...