DOSEN PROFIL LENGKAP

cerevisiae, and the fission yeast S. pombe, where it is encoded by genes cdc28 and cdc2, respectively. With its cyclin partners, Cdk1 forms complexes that...

fundamental role of checkpoints in cell cycle control, and CDC genes such as CDC28, which controls the start of the cycle—the progression through G1. Hartwell...

the CLN3 protein, which is needed for the accumulation of Cdc28. In late G1, however, Cdc28 has been observed to localize to the nucleus. Another, more...

dissociates with Cdc28 and complexes between Cdc28 and Clb5 or Clb6 are formed. In G2 phase, complexes formed from the association between Cdc28 and Clb1, Clb2...

members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators...

protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, also known as Cdk1 in humans. It is a catalytic subunit...

G1 phase of the cell cycle, Sic1 binds tightly to the Cdc28-Clb complex and inhibits it. Low Cdc28-Clb activity leads to the disassembly of the mitotic...

S. cerevisiae homologue Swe1 In S. cerevisiae, cyclin-dependent kinase Cdc28 (Cdk1 homologue) is phosphorylated by Swe1 (Wee1 homologue) and dephosphorylated...

phosphorylation of Orc2, Orc6, Cdc6, and MCM by the cyclin-dependent protein kinase Cdc28 regulates initiation of DNA replication, including blocking reinitiation...

sequence. Furthermore, Cdc6 indirectly inhibits activation of the p34cdc2/CDC28 M phase kinase, thus nuclear division is suppressed. CDC6 is normally present...

available. This regulation is accomplished by the cyclin-dependent kinase Cdk1 (Cdc28 in yeast), which is turned off in G1 and expressed in S and G2. Cdk1 phosphorylates...

members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators...

cerevisiae yeast expressing dominant mutant alleles of CDC28 arrest in G1, which indicates that CDC28 is necessary for passage beyond the G1 phase. S: Schizosaccharomyces...

at various stages of the cycle. Hartwell not only identified the mutant, cdc28, which arrests in very early stages of the cell cycle, but he also recognised...

(8): 1332–44. doi:10.1101/gad.4.8.1332. PMID 2227411. "Entrez Gene: CKS1B CDC28 protein kinase regulatory subunit 1B". Harper, J.W. 2001. Protein destruction:...

from the various cyclin-dependent kinases (CDKs). In yeast, just one CDK (Cdc28 in S. cerevisiae and Cdc2 in S. pombe) controls the cell cycle. However...

increased CLB2 mRNA and protein. Maintained CLB2 protein levels allows Cdc28 (a cyclin-dependent kinase) to remain active and inhibit the end of mitosis...

during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the...

demonstrated that CDC28 protein kinase is not required for the metaphase to anaphase transition and CLB2 proteolysis continues until reactivation of CDC28 toward...

and CLN2, upon transcriptional activation by Cln3 in mid-G1, bind Cdk1 (Cdc28) to complete progression through Start. These cyclins oscillate during the...

When DNA replication begins in budding yeast, the cyclin-dependent kinase Cdc28 begins homologous recombination by phosphorylating the Sae2 protein. After...

73 (3): 250–4. doi:10.1159/000134349. PMID 8697818. "Entrez Gene: CKS2 CDC28 protein kinase regulatory subunit 2". Human CKS2 genome location and CKS2...

Johnson KW, Smith KA (1991). "Molecular cloning of a novel human cdc2/CDC28-like protein kinase". J. Biol. Chem. 266 (6): 3402–7. doi:10.1016/S0021-9258(19)67807-5...

dissociation of Whi5 from SBF through inhibitory hyperphosphorylation. Cdc28 CDK is also believed to involve in this process, which is activated by Cln1...

viruses. The yeast homologue of cyclin D, referred to as CLN3, interacts with Cdc28 (cell division control protein) during G1. In viruses, like Saimiriine herpesvirus...

The CDK4 protein is similar to the fungi gene products of S. cerevisiae cdc28 and S. pombe cdc2. CDK4 is the catalytic subunit of the protein-kinase complex...

or regulon in budding yeast includes the G1 cyclins Cln1, Cln2 and Cln3, Cdc28 (Cdk1), the transcription factors SBF and MBF, and the transcriptional inhibitor...

new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1". EMBO...

function in vivo. Cdh1 contains multiple phosphorylation sites for the kinase cdc28. When cdh1 is hyperphosphorytaled, the association of cdh1 to the APC/c...

an enzyme that in humans is encoded by the CDK3 gene. CDK3 complements cdc28 mutants of Saccharomyces cerevisiae suggesting that it may be involved in...

Mary–Jane; Sambrook, Joseph (1993). "A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus"...

family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase...

in the presence of Cdc45. Binding of Cdc45 to chromatin depends on Clb-Cdc28 kinase activity as well as functional Cdc6 and Mcm2, which suggests that...

subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression...

Bond J, Walder K, Augert G, Collier G (2003). "Beacon interacts with cdc2/cdc28-like kinases". Biochem. Biophys. Res. Commun. 304 (1): 125–9. doi:10...

catalytic domain - CCR5 receptor - CD4 antigen - CD45 antigen - CD95 antigen - CDC28 protein kinase - cell - cell adhesion molecule - cell biology - cell cycle...

Downing JR (Dec 1992). "PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family". Oncogene. 7 (11): 2249–58. PMID 1437147...

several other substrates than Sic1 to the SCF core complex, including the Cln-Cdc28 inhibitor / cytoskeletal scaffold protein Far1, the transcription factor...

– cdc2-cdc28 kinases MeSH D08.811.913.696.620.682.700.200.067.249 – cdc2 protein kinase MeSH D08.811.913.696.620.682.700.200.067.500 – cdc28 protein...

Downing JR (Dec 1992). "PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family". Oncogene. 7 (11): 2249–58. PMID 1437147...

proteolysis are necessary. However, experiments using budding yeast cells with cdc28-as1, an INM-PP1 (ATP analog)-sensitive Cdk allele, proved that destruction...

776.476.250.067.249 – cdc2 protein kinase MeSH D12.776.476.250.067.500 – cdc28 protein kinase, s cerevisiae MeSH D12.776.476.250.067.875 – cyclin-dependent...

complementation in yeast and, in collaboration with Steve Reed, cloned the CDC28 gene from the budding yeast Saccharomyces cerevisiae. As a group leader...

of a human DEAH-box RNA helicase, a functional homolog of fission yeast Cdc28/Prp8". Nucleic Acids Res. 26 (9): 2063–8. doi:10.1093/nar/26.9.2063. PMC 147520...

Kantham L, Kerr-Bayles L, Godde N, et al. (2003). "Beacon interacts with cdc2/cdc28-like kinases". Biochem. Biophys. Res. Commun. 304 (1): 125–9. doi:10...

776.167.200.067.249 – cdc2 protein kinase MeSH D12.776.167.200.067.500 – cdc28 protein kinase, s cerevisiae MeSH D12.776.167.200.067.875 – cyclin-dependent...

644.360.250.067 – cdc2-cdc28 kinases MeSH D12.644.360.250.067.249 – cdc2 protein kinase MeSH D12.644.360.250.067.500 – cdc28 protein kinase, s cerevisiae...