Search Results: CaMKII


Ca2+/calmodulin-dependent protein kinase II
Jumat, 2025-05-23 20:38:05

activation of the CaMKII enzyme. This enables CamKII to be active, even in the absence of calcium and calmodulin. The other two domains in CaMKII are the variable...

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Synapse
Selasa, 2026-06-02 21:43:39

function of CaMKII in memory storage was demonstrated While Ca2+/CaM binding stimulates CaMKII activity, Ca2+-independent autonomous CaMKII activity can...

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Amphetamine
Senin, 2026-06-08 18:27:08

to activate CaMKII in DAT transfected cells (Wei et al., 2007). ... At present, information is lacking as to the site(s) that support CaMKII phosphorylation...

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CAMK
Minggu, 2025-11-23 21:59:15

(CAMK1) CAMKIβ (PNCK) CAMKIδ CAMKIγ (CAMK1G) CAMKII CAMKIIα CAMKIIβ CAMKIIδ CAMKIIγ CAMKIII CAMKIV CAMKV CaM kinase like vesicle associated SCAMK...

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AMPA receptor
Rabu, 2026-05-06 12:02:46

potentiation (LTP; for GluA1's role in LTP, see below). S831 is phosphorylated by CaMKII and PKC during LTP, which helps deliver GluA1-containing AMPAR to the synapse...

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Long-term potentiation
Minggu, 2025-09-28 08:31:05

synaptic plasticity. While induction entails the transient activation of CaMKII and PKC, maintenance of E-LTP (early-form LTP) is characterized by their...

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Synaptic plasticity
Kamis, 2026-05-07 19:30:04

levels of key proteins such as CaMKII and PKAII. Activation of the second messenger pathway leads to increased levels of CaMKII and PKAII within the dendritic...

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Shigella
Selasa, 2026-04-21 18:02:35

which mimics the interaction with CaMKII. As a result, CaM mistakenly recognizes the bacterial proteins as CaMKII, preventing the normal function of...

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Dendritic spine
Kamis, 2025-10-09 04:55:25

kinases II (CaMKII). In turn, CaMKII is activated and this activates Cdc42, after which no feedback signaling occurs upstream to calcium and CaMKII. If tagged...

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Angelman syndrome
Rabu, 2026-06-03 17:26:54

phosphorylation of CaMKII in primary cortical neurons. CamKII plays a primary role in learning and memory. Therefore, dysfunction of CaMKII signalling in the...

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Calcium signaling
Kamis, 2026-06-04 02:04:03

calmodulin (CaM), which exposes its hydrophobic residues and activates the molecule. CaM binds to calmodulin-dependent protein kinase II (CaMKII), which phosphorylates...

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Sally Kornbluth
Selasa, 2026-06-02 04:12:18

(October 7, 2005). "Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2". Cell. 123 (1): 89–103. doi:10.1016/j...

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Olfactory receptor neuron
Senin, 2026-05-18 01:45:14

form CaM. CaM will then bind to the CNG channel and close it, stopping the sodium and calcium influx. CaMKII will be activated by the presence of CaM, which...

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Calmodulin
Selasa, 2026-04-21 17:54:49

inhibiting CaMKII interferes with LTP. While yeasts have only a single CaM gene, plants and vertebrates contain an evolutionarily conserved form of CaM genes...

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Synaptic tagging
Jumat, 2025-12-12 14:11:05

Granules containing two proteins of known importance to synaptic plasticity, CaMKII (Calmodulin-dependent Kinase II) and the immediate early gene Arc, have...

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Wnt signaling pathway
Senin, 2026-03-02 01:41:12

and CaMKII. Calcineurin induces activation of the transcription factor NFAT, which regulates cell adhesion, migration and tissue separation. CaMKII activates...

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Substance dependence
Sabtu, 2026-04-11 01:45:20

in NMDA receptor subunits NR1 and NR2A, phosphorylated CaMKII, and c-fos. Expression of CaMKII and c-fos is attenuated by NMDA receptor antagonists, which...

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Dopamine transporter
Kamis, 2026-03-26 16:33:29

believed to induce CAMKII-mediated phosphorylation of the dopamine transporter as a downstream effect; since DAT phosphorylation by CAMKII results in dopamine...

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Apical dendrite
Selasa, 2026-03-17 03:12:33

is CaMKII a calcium/calmodulin-regulated serine/threonine kinase which is required for induction by not expression of long-term potentiation. CaMKII mRNA...

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Protein kinase
Senin, 2026-05-25 12:02:06

Calcium/calmodulin-dependent protein kinase II (CaMKII) is an example of a serine/threonine-specific protein kinase....

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Fiber photometry
Selasa, 2026-04-28 20:02:23

cell-specific promoters like Ca2+/calmodulin-dependent protein kinase II (CaMKII) and human synapsin (hSyn) that confer excitatory neuronal and pan-neuronal...

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Monoamine releasing agent
Jumat, 2026-04-10 10:43:16

calmodulin kinase IIα (αCaMKII). Here, we show that not only DAT, but also SERT, is regulated by αCaMKII. Inhibition of αCaMKII activity markedly decreased...

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Phosphoinositide 3-kinase
Kamis, 2026-03-26 20:53:04

glutamatergic synapses. PI3Ks are phosphorylated upon NMDA receptor-dependent CaMKII activity, and it then facilitates the insertion of AMPA-R GluR1 subunits...

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Myocardial contractility
Jumat, 2026-04-24 21:59:52

Dobromir; Meyhöfer, Svenja; Langer, Harald F.; Maier, Lars S. (August 2020). "CaMKII activity contributes to homeometric autoregulation of the heart: A novel...

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Timothy syndrome
Minggu, 2025-10-05 07:41:46

slowing of cardiac impulse propagation. Single cell studies identified that CaMKII autophosphorylation reduced the peak sodium current, thus causing the slowing...

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Spike-timing-dependent plasticity
Minggu, 2025-11-02 06:12:01

Calcium influx through NMDA receptors activates CaMKII, which initiates signaling cascades involving Rho family GTPases, primarily RhoA and Cdc42. These...

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Adderall
Rabu, 2026-05-06 22:19:47

intracellular calcium (Gnegy et al., 2004) that is associated with calmodulin/CamKII activation (Wei et al., 2007) and modulation and trafficking of the DAT...

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Calcium signaling in cell division
Rabu, 2026-05-20 00:20:09

cancer cell lines, that the G2/M checkpoint is regulated by CaMKII and MAPK crosstalk. Here, CaMKII activates MEK/ERK, which degrades the cell cycle arresting...

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Autophosphorylation
Selasa, 2026-01-13 17:08:57

tails Ser/Thr phosphorylation sites: C. elegans CaMKII, C-terminal tail, Thr284 (PDB: 3KK8, 3KK9) human CaMKII, C-terminal tail, Thr287 (PDB: 2WEL, homologous...

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Autoregulation
Kamis, 2025-05-15 11:00:19

LS; Linz, D; Mügge, A; Hohl, M; Steendijk, P; Hamdani, N (August 2020). "CaMKII activity contributes to homeometric autoregulation of the heart: A novel...

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SYNGAP1
Rabu, 2026-05-20 18:53:12

PMID 15014045. Song B, Yan XB, Zhang GY (April 2004). "PSD-95 promotes CaMKII-catalyzed serine phosphorylation of the synaptic RAS-GTPase activating protein...

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Leducq Foundation
Kamis, 2025-11-13 22:25:11

PMC 4343103. PMID 25646445. Anderson, M. E.; Brown, J. H.; Bers, D. M. (2011). "CaMKII in myocardial hypertrophy and heart failure". Journal of Molecular and Cellular...

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Phyllis Gardner (clinical pharmacologist)
Rabu, 2026-04-08 00:59:12

Gardner, P. (1995), "Calcium-dependent and CaMKII-dependent chloride secretion induced by the microsomal Ca²⁺-ATPase inhibitor 2,5-di-(tert-butyl)-1,4-hydroquinone...

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O-GlcNAc
Selasa, 2026-03-24 06:05:26

It has also been suggested that this effect is dependent on calcium and CaMKII. Activated p38 is able to recruit OGT to specific protein targets, including...

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Brain-derived neurotrophic factor
Jumat, 2026-05-15 22:03:59

receptor and promoting the synaptic localization of GluR1 via PKC- and CaMKII-mediated Ser-831 phosphorylation. It also appears that BDNF is able to influence...

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Ira Tabas
Senin, 2026-05-25 03:29:47

calcium-release channel IP3R, a calcium-sensitive protein kinase called CaMKII, and an oxidative stress-generating enzyme NADPH Tabas developed nanoparticles...

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Dextroamphetamine
Senin, 2026-06-08 19:19:17

intracellular calcium (Gnegy et al., 2004) that is associated with calmodulin/CamKII activation (Wei et al., 2007) and modulation and trafficking of the DAT...

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Methamphetamine
Senin, 2026-06-08 19:52:56

intracellular calcium (Gnegy et al., 2004) that is associated with calmodulin/CamKII activation (Wei et al., 2007) and modulation and trafficking of the DAT...

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D1–D2 dopamine receptor heteromer
Rabu, 2025-10-01 02:05:50

calcium release from inositol trisphosphate receptor-sensitive stores, CaMKII activation and BDNF production. In comparison, signalling of the homologous...

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Epigenetics of cocaine addiction
Selasa, 2026-05-12 19:28:25

which mediate the export of HDAC5 out of the nucleus. They also found that CaMKII was necessary for depolarization-induced HDAC5 phosphorylation in NAc tissue...

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Glycogen synthase
Kamis, 2026-03-26 02:08:16

Phosphorylation site Kinase Reference(s) Site 1a Ser 697 PKA Site 1b Ser 710 PKA, CaMKII Site 2 Ser 7 PKA, PhK, AMPK Site 2a Ser 10 CK1 Site 3a Ser 640 GSK-3 Site...

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Monoamine transporter
Minggu, 2025-08-10 05:11:14

SERT has been linked to acute depletion of intracellular Ca Na 2+, calmodulin inhibition, CaMKII, Src, p38 MAP kinase, PKC, and activation of NOS/cGMP....

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Sunifiram
Senin, 2026-02-23 11:14:14

their memory-enhancing effects. It is reported that sunifiram stimulates CaMKII and PKCα pathways, and that this action depends on the activation of glycine...

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3-Iodothyronamine
Selasa, 2026-04-07 07:34:24

In addition, T1AM-mediated TH phosphorylation appeared to be mediated by CaMKII and protein kinase A (PKA) signaling. T1AM was also found to increase electrically...

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Ultrasensitivity
Selasa, 2025-11-18 12:16:33

mediated by cooperative binding of CaMKII by two molecules of calmodulin (CaM), and autophosphorylation of activated CaMKII leading to a positive feedback...

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Silent synapse
Senin, 2026-03-30 07:56:17

protein kinase II (CaMKII), which — among other things — acts on AMPAR-containing vesicles near the postsynaptic membrane. CaMKII phosphorylates these...

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Dishevelled
Selasa, 2025-05-20 13:32:29

triggering a cascade leading to Ca2+ release, which activates effectors (e.g. CaMKII) that control gene transcription relevant to cell fate and cell migration...

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Κ-opioid receptor
Senin, 2026-06-08 20:55:15

triggers rapid, concentration-dependent upregulation of SERT function through CaMKII and Akt. This increased trafficking of SERT to the plasma membrane, enhances...

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Anrep effect
Sabtu, 2026-01-31 22:09:48

Dobromir; Meyhöfer, Svenja; Langer, Harald F.; Maier, Lars S. (August 2020). "CaMKII activity contributes to homeometric autoregulation of the heart: A novel...

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Biochemical cascade
Kamis, 2026-03-05 00:05:57

into the oocyte leading to an increase in Ca2+ levels that will activate CaMKII which will degrade MPF, leading to the resumption of meiosis. The increased...

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Calpainopathy
Sabtu, 2025-12-13 23:19:09

found at the triad are reduced, including CaMKII (Ca2+/calmodulin-dependent protein kinase II). Decreased CaMKII activity impairs induction of slow oxidative...

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Catenin beta-1
Rabu, 2026-04-01 20:25:44

(CaMKII). Activated CaMKII destabilizes β-catenin via a poorly characterized mechanism, but which likely involves β-catenin phosphorylation by CaMKII....

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Barrel cortex
Rabu, 2025-10-22 08:08:36

enzymes related to LTP and LTD e.g. calmodulin-dependent protein kinase II (CaMKII) or cyclic-AMP response element binding protein (CREB). In these mice, plasticity...

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De novo protein synthesis theory of memory formation
Senin, 2026-04-06 21:36:03

Poncer JC, Poncer M (2000). "Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction". Science. 287 (5461):...

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Addiction
Sabtu, 2026-05-09 17:15:45

Life. Retrieved 17 September 2018. Clarke TK, Crist RC, Kampman KM, Dackis CA, Pettinati HM, O'Brien CP, et al. (2013). "Low frequency genetic variants...

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Ankyrin-2
Kamis, 2025-10-02 05:30:25

Nixon D, Koval O, Curran JW, Wright P, Wang Q, et al. (December 2012). "CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B...

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Calcium/calmodulin-dependent protein kinase type II subunit alpha
Jumat, 2025-08-08 18:05:48

a. Ca2+/calmodulin-dependent protein kinase II alpha, is one subunit of CamKII, a protein kinase (i.e., an enzyme which phosphorylates proteins) that in...

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Camilla Bellone
Minggu, 2026-04-26 20:12:50

PSD-95 drives hippocampal neuronal cell death through activation of an alpha CaMKII transduction pathway". The European Journal of Neuroscience. 16 (5): 777–86...

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Alcino J. Silva
Jumat, 2026-05-29 01:37:28

P.W.; O'Brien, C.; Ohno, M.; Kirkwood, A.; Silva, A.J. (2001). "Alpha-CaMKII-dependent plasticity in the cortex is required for permanent memory". Nature...

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Adenosine A1 receptor
Rabu, 2026-06-03 03:10:56

"Stimulation of ANP secretion by 2-Cl-IB-MECA through A(3) receptor and CaMKII". Peptides. 29 (12): 2216–2224. doi:10.1016/j.peptides.2008.09.003. PMID 18838091...

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Molecular and epigenetic mechanisms of alcoholism
Kamis, 2025-12-11 23:37:28

showed a decrease in CaMKIV and consequently p-CREB. In contrast, ethanol activates CaMKII resulting in phosphorylation of CaMKII targets such as BK potassium...

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Topoisomerase inhibitor
Senin, 2025-12-29 15:53:21

A, protein kinase C and calcium/calmodulin-dependent protein kinase II (CaMKII), a kinase integral in controlling calcium ion channels in cardiomyocites...

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PPP1R1B
Rabu, 2025-10-08 02:44:31

possibly by serving as a dopamine-dependent gating mechanism for calcium/CaMKII signaling. It has been predicted that DARPP-32, in conjunction with ARPP-21...

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Cocaine and amphetamine regulated transcript
Minggu, 2026-04-19 19:10:28

"A New Insight into the Role of CART in Cocaine Reward: Involvement of CaMKII and Inhibitory G-Protein Coupled Receptor Signaling". Frontiers in Cellular...

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Ravi Iyengar
Jumat, 2026-05-29 10:20:09

reporting that cAMP-dependent regulation of protein phosphatase 1 can gate CaMKII signaling during long-term potentiation in hippocampal neurons. Iyengar...

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Roger Y. Tsien
Jumat, 2026-02-06 17:30:23

Boxing; Tsien, Richard W. (2015). "Distinct roles of multiple isoforms of CaMKII in signaling to the nucleus". Biochimica et Biophysica Acta (BBA) - Molecular...

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DNM1L
Senin, 2025-09-29 22:25:04

activating, whereas PKA phosphorylation is thought to be inhibitory. Recently, CaMKII was shown to phosphorylate Drp1 at S616. This was shown to occur in response...

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Multi-state modeling of biomolecules
Sabtu, 2026-02-21 01:00:44

methylation sites, resulting in billions of potential states. The protein kinase CaMKII is a dodecamer of twelve catalytic subunits, arranged in two hexameric rings...

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Optogenetic methods to record cellular activity
Selasa, 2026-06-02 14:29:18

Escobedo-Lozoya Y, Szatmari EM, Yasuda R (March 2009). "Activation of CaMKII in single dendritic spines during long-term potentiation". Nature. 458 (7236):...

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Susumu Tonegawa
Selasa, 2026-04-14 19:26:02

systems. He was involved in early work demonstrating the importance of CaMKII- (1992) and the NMDA receptor-dependent synaptic plasticity (1996) in memory...

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Muscarinic acetylcholine receptor M4
Senin, 2026-06-08 05:31:06

pharmthera.2007.09.009. PMID 18082893. Stein IS, Hell JW (June 2010). "CaMKII hunkers down on the muscarinic M4 receptor to help curb cocaine-induced...

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Hollis Cline
Senin, 2024-11-25 01:45:16

Award Lisman, J.; Schulman, H.; Cline, H. (2002). "The molecular basis of CaMKII function in synaptic and behavioural memory". Nature Reviews Neuroscience...

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Homosynaptic plasticity
Senin, 2026-05-18 08:01:00

within the cell. To induce long-term potentiation (LTP), Ca2+ activates CAMKII and PKC, causing phosphorylation and insertion of AMPARs, while long-term...

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Mushroom bodies
Rabu, 2026-03-04 05:24:47

that have been mapped depend on activity and protein synthesis of CREB and CaMKII, and only exist after spaced conditioning. The first trace is detected in...

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Ryanodine receptor 2
Senin, 2025-08-11 12:51:27

PRKACB, PRKACG,) (phosphorylation at serine position S2808 in rodents) CaMKII (via phosphorylation at serine positions S2808 and S2814 in humans and rodents...

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EEA1
Minggu, 2025-11-30 21:55:37

known to inhibit the recruitment of EEA1 to the phagosomal membrane through CamKII. Legionella pneumophila also prevents EEA1 recruitment through a currently...

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FOSB
Jumat, 2026-02-13 13:03:19

Sun H, Maze I, Gancarz AM, Vialou V, Koo JW, Mouzon E, Ghose S, Tamminga CA, Nestler EJ (February 2014). "ΔFosB induction in prefrontal cortex by antipsychotic...

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Gap junction modulation
Sabtu, 2025-05-24 06:24:12

kinase C (PKC), protein kinase G (PKG), Ca2+/calmodulin-dependent kinase II (CaMKII), cAMP-dependent protein kinase A (PKA), MAP kinase (MAPK) and casein kinase...

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SYNPO2
Jumat, 2025-07-18 01:31:10

calcineurin, CaMKII, muscle-specific A-kinase anchoring protein, and myomegalin. Specifically, phosphorylation by protein kinase A or CaMKII, and dephosphorylation...

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Actin remodeling of neurons
Selasa, 2026-02-24 06:09:19

PSDZ, while also providing scaffolding for plasticity products such as CAMKII. F-actin could serve as a synaptic tag because the scaffolding space for...

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Behavioral epigenetics
Jumat, 2026-03-20 12:22:02

signaling elevates Ca2+ levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating...

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Channelrhodopsin
Kamis, 2026-05-28 07:38:51

plasticity at single synapses reveals input-specific accumulation of alphaCaMKII". Proceedings of the National Academy of Sciences of the United States of...

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Membrane-associated guanylate kinase
Senin, 2024-09-09 23:51:35

and GUK domains, although many of them also contain regions homologous of CaMKII, WW and L27 domains. The GUK domain that they have is structurally very...

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Beta-adrenergic agonist
Senin, 2026-03-02 17:28:07

(October 2009). "β1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial...

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Protein c-Fos
Kamis, 2026-04-02 02:19:02

signaling elevates Ca2+ levels in NAc postsynaptic elements where it activates CaMK (calcium/calmodulin protein kinases) signaling, which, in addition to phosphorylating...

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BCPNN
Senin, 2026-02-02 23:47:10

conjunction of these events lead to C a 2 + {\displaystyle Ca^{2+}} influx via NMDA channels, CaMKII activation, AMPA channel phosphorylation, and eventually...

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SB-366791
Kamis, 2026-01-01 02:43:44

2018). "TRPV1 modulates morphine self-administration via activation of the CaMKII-CREB pathway in the nucleus accumbens". Neurochemistry International. 121:...

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Myosin binding protein C, cardiac
Senin, 2025-11-03 11:34:07

phosphorylate cMyBP-C in the M motif are PKA, Ca2+/calmodulin-dependent kinase II (CaMKII), ribosomal s6 kinase (RSK),protein kinase D (PKD), and protein kinase C...

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Metaplasticity
Senin, 2025-11-03 04:07:55

respectively. Recent research has found that the calcium-dependent enzyme CaMKII, which exists in an alpha and beta isoform, is key in inactivity-dependent...

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Basic helix–loop–helix
Senin, 2025-10-27 01:29:06

Myf5 Beta2/NeuroD1 Scl, also known as Tal1 proneural bHLH genes like p-CaMKII, and pSer(336)NeuroD. Neurogenins MAX C-Myc, N-Myc TCF4 (Transcription Factor...

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MPDZ
Kamis, 2025-12-18 14:32:56

Krapivinsky G, Medina I, Krapivinsky L, Gapon S, Clapham DE (2004). "SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent...

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Lisdexamfetamine
Kamis, 2026-05-28 08:41:01

intracellular calcium (Gnegy et al., 2004) that is associated with calmodulin/CamKII activation (Wei et al., 2007) and modulation and trafficking of the DAT...

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RICS (gene)
Jumat, 2025-07-18 01:11:04

regulated by two phosphorylation sites, one controlled by CaMKII, and the other by RPTPa. When CaMKII is activated by Ca2+ entry through NMDA receptors and...

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CCAAT-enhancer-binding proteins
Rabu, 2026-05-06 23:11:11

Youjun; Dabas, Hadas; Hammarlund, Marc (2022-03-14). "Activation of the CaMKII-Sarm1-ASK1-p38 MAP kinase pathway protects against axon degeneration caused...

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Nicolas Le Novère
Senin, 2026-05-11 12:32:11

allosteric model of calmodulin explains differential activation of PP2B and CaMKII". Proceedings of the National Academy of Sciences. 105 (31): 10768–10773...

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LRRC7
Kamis, 2025-07-17 00:50:20

Laboratory. Identified interaction partners include: CaMKII-alpha, alpha-Actinin and NR2B (via CaMKII-alpha), Cav1.3 (L-type Ca2+) channels, MAGUIN-1, Shank...

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Ertugliflozin
Kamis, 2025-12-25 02:21:13

source is acknowledged. Trum M, Wagner S, Maier LS, Mustroph J (June 2020). "CaMKII and GLUT1 in heart failure and the role of gliflozins". Biochimica et Biophysica...

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GRIN2A
Minggu, 2026-05-10 23:57:40

Fiorentini C, Bellone C, Missale C, Cattabeni F, et al. (November 2003). "CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction". The Journal...

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NCDN
Rabu, 2025-07-16 05:02:47

Nagao Y, Ishida J, et al. (May 2005). "Neurochondrin negatively regulates CaMKII phosphorylation, and nervous system-specific gene disruption results in...

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Fluorescence-lifetime imaging microscopy
Selasa, 2025-09-16 03:10:17

neurons, FLIM imaging using pulsed illumination has been used to study Ras, CaMKII, Rac, and Ran family proteins. FLIM has been used in clinical multiphoton...

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Timeline of aging research
Kamis, 2026-05-28 02:14:57

behind cognitive decline in aging, the mis-regulation of the brain protein CaMKII. Three studies indicate platelets, including or especially FF4, are exerkines...

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Daf-16
Senin, 2025-10-20 21:23:36

Zhang, Yan-Ping; Tan, Dan; Yuan, Zengqiang; Dong, Meng-Qiu (25 June 2013). "CAMKII and calcineurin regulate the lifespan of Caenorhabditis elegans through...

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Gerald I. Shulman
Senin, 2026-03-23 14:41:28

and how glucagon stimulates gluconeogenesis via the IP3R1 receptor and CaMKII. His research has also explored how adiponectin, leptin, and fibroblast...

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BAALC
Minggu, 2025-11-23 22:08:16

associate with the CAMKII alpha subunit and not with the beta subunit. The interaction with the CAMKII alpha subunit is in the CAMKII protein's regulatory...

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Mary B. Kennedy
Selasa, 2025-09-30 22:57:53

synaptic signaling protein Calcium/calmodulin-dependent protein kinase II (CaMKII) in 1983 and showed that it is 1-2% of forebrain protein, is a major constituent...

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Neuronal memory allocation
Jumat, 2026-04-24 20:51:47

implicated in these metaplastic effects include autophosphorylation of αCaMKII, changes in NMDA receptor subunit composition, and activation of voltage-dependent...

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MAP6
Senin, 2025-10-20 08:14:16

the Ca+2-CaM complex forms, where it detaches MAP6 from adjacent microtubules, and activates Ca+2/calmodulin-dependent protein kinase II (CaMKII). When...

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SCN5A
Minggu, 2025-08-03 17:45:15

"Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias". American Journal of...

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DLGAP4
Sabtu, 2025-07-19 12:38:11

1038/ng1285. PMID 14702039. Song B, Yan XB, Zhang GY (2004). "PSD-95 promotes CaMKII-catalyzed serine phosphorylation of the synaptic RAS-GTPase activating protein...

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Death effector domain
Senin, 2026-03-02 01:46:30

Ser116: the substrate for calcium/calmodulin-dependent protein kinase II (CamKII). PEA-15 works as an antiapoptotic DED protein in several signaling cascades...

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RAPGEF4
Jumat, 2025-11-28 09:04:26

chronic stimulation of Epac2 may be a cause of cardiac arrhythmia through CaMKII-dependent diastolic sarcoplasmic reticulum (SR) Ca2+ release in mice. Epac2...

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GRIA1
Senin, 2025-10-27 23:16:29

Fiorentini C, Bellone C, Missale C, Cattabeni F, Di Luca M (November 2003). "CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction". J. Biol. Chem...

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EPPTB
Minggu, 2025-12-21 04:34:43

expected functional activity in DStr slices ex vivo. This effect involved CaMKII and PKA activation. In accordance with the enhanced expected TH activity...

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Calcium/calmodulin dependent protein kinase II inhibitor 1
Jumat, 2026-03-20 10:48:45

Wang C, Li N, Liu X, Zheng Y, Cao X (2008). "A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest...

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Mir-1 microRNA precursor family
Selasa, 2025-10-07 21:19:55

overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation...

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4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene
Rabu, 2025-10-01 22:45:01

PMID 36587891. S2CID 255295147. Erickson, J. R. (2014). "Mechanisms of camkii activation in the heart". Frontiers in Pharmacology. 5: 59. doi:10.3389/fphar...

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DLG4
Kamis, 2025-07-31 20:47:58

and GUK domains, although many of them also contain regions homologous of CaMKII, WW and L27 domains. The GUK domain that they have is structurally very...

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Ivan Izquierdo
Minggu, 2025-03-09 14:52:08

and its maintenance depend on L-voltage-dependent calcium channels and CaMKII functions regulating protein turnover in the hippocampus". Proceedings of...

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Hailan Hu
Rabu, 2026-04-22 18:24:57

Henn, Fritz; Malinow, Roberto; Yates, John R.; Hu, Hailan (2013-08-30). "βCaMKII in Lateral Habenula Mediates Core Symptoms of Depression". Science. 341...

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TAAR1
Jumat, 2026-05-22 00:20:10

intracellular calcium (Gnegy et al., 2004) that is associated with calmodulin/CamKII activation (Wei et al., 2007) and modulation and trafficking of the DAT...

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Inositol-trisphosphate 3-kinase
Kamis, 2026-03-05 02:19:14

stimulated by phosphorylation by calcium/calmodulin-dependent kinase II (CaMKII). In addition, there is evidence that ITP3Ks may be activated upon phosphorylation...

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SMAD7
Jumat, 2026-01-30 11:46:20

Erk-family MAP kinases, the Ca2+ /calmodulin-dependent protein kinase II (CamKII) and protein kinase C (PKC). Smad7 does not have the MH1 domain. A proline-tyrosine...

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Calmodulin 1
Selasa, 2025-09-30 23:03:00

Calcium/calmodulin protein kinases (CaMKs) work symbiotically to regulate calcium signaling throughout the body. CAMKII, the most prolific isoform, is found...

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CNKSR2
Minggu, 2025-09-21 18:17:09

Densin-180 without the presence of CNKSR2. This brings it into a complex with CamKII and β-catenin, and further to the binding partners of CNKSR2 suggest that...

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CAMK2D
Kamis, 2025-07-17 22:54:50

Nair JS, DaFonseca CJ, Tjernberg A (Apr 2002). "Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma". Proceedings...

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Optogenetics
Kamis, 2026-06-04 14:44:01

Optophysiology Laboratory of Donald C. Cooper Ph.D. showing individual CAMKII AAV-ChR2 expressing pyramidal neurons within the prefrontal cortex that...

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They're Coming to Take Me Away, Ha-Haaa!
Senin, 2026-05-04 21:09:25

2018-08-16. Cash Box Top 100 Singles, July 30, 1966 "M-Audio Fast Track MKII USB Audio Interface". Guitar Center. 2011-12-29. Retrieved 2016-09-29. "The...

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3D-printed firearm
Kamis, 2026-05-28 17:09:17

3D-printed FGC-9 pistol caliber carbine. Test firing of a 3D-printed FGC-9 MkII pistol caliber carbine (closeup, slow motion). ROGUE-9 FTN3 Long version...

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Type 212CD submarine
Minggu, 2026-05-31 04:52:22

system will be installed while Kongsberg will contribute the active SA9510S MKII Mine Avoidance and Navigation Sonar as well as echo sounders for navigation...

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Steve Ritchie (pinball designer)
Selasa, 2026-06-02 18:21:20

video games. He played the voice of Shao Kahn in the Mortal Kombat series (MKII, MK3, UMK3, MKT, MK:SM), and created the name of Mortal Kombat, which was...

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List of equipment of the Myanmar Army
Minggu, 2026-05-31 01:25:54

Canada Socialist Republic of the Union of Burma / Union of Myanmar MA-5 MKII Semi-automatic pistol Clone of second-generation Glock models 9×19mm Parabellum...

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BMW 5 Series (E39)
Jumat, 2026-05-22 17:10:07

equipment Satellite navigation upgraded from MKI (or Mark I) to MKII. Like the MKI, the MKII uses a 4:3 screen and stores the maps on a CD. Rain-sensing windshield...

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Aston Martin
Sabtu, 2026-05-23 17:25:30

cars". They included the 1½-litre "T-type", "International", "Le Mans", "MKII" and its racing derivative, the "Ulster", and the 2-litre 15/98 and its racing...

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Hindustan Aeronautics Limited
Minggu, 2026-05-31 14:23:06

integrated L-40 stages for GSLV Mk II, propellant tanks, feed lines of PSLV, GSLV MKII and GSLV MKIII launch vehicles and structures of various satellites. HA-31...

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Breechblock
Senin, 2026-06-08 17:16:10

Rifle - from the mind of the genius, accessed 15 July 2021. How does Bren MKII work?, accessed 15 July 2021. America's Forgotten Military Rifle: M1895 Lee...

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Avro Anson
Jumat, 2026-06-05 22:53:43

the original on 17 December 2016. Retrieved 16 December 2016. "AVRO ANSON MKII". Greenwood Military Aviation Museum. GMAM. Retrieved 16 December 2016. "Avro...

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Shelby American
Jumat, 2026-05-15 09:02:54

total- 19,962 AC Cobra CSX Dakota Daytona GLH-S Lancer Mustang Series 1 GT40 MKII (Shelby team) With the worldwide release of the sixth generation Ford Mustang...

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Ford Transit
Minggu, 2026-06-07 09:26:03

Group's Commer PB ranges. In a UK market segment then dominated by the Bedford CA, the Thames' restricted load area failed to attract fleet users in sufficient...

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Chevrolet
Minggu, 2026-06-07 02:37:24

hatchback, Chevrolet Onix. The latest home-grown product is the Chevrolet Prisma MKII, released in 2013. Utility and four-wheel drive vehicles line-up includes...

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Mark Donohue
Senin, 2026-05-25 09:36:11

Ford Motor Company about the young driver. Ford signed Donohue to drive a MKII GT40 at the 24 Hours of Daytona in a deal made by Hangsen himself, and after...

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International MaxxPro
Kamis, 2026-04-30 10:45:23

21 September 2013. "YPD gets armored truck". Siskiyou Daily News, Yreka, CA. Archived from the original on 5 November 2014. Retrieved 4 November 2014...

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C&C Yachts
Kamis, 2026-05-28 00:59:56

in 2014. Models include: C&C 1/2 Ton 1975 C&C 24 1975 C&C 25 1973 C&C 25 MKII 1980 C&C 25 Redline 1969 C&C 26 1976 C&C 26 Encounter 1978 C&C 26 Wave 1988...

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Joe Perry (musician)
Rabu, 2026-05-27 23:53:54

Merry Christmas (2014) Sweetzerland Manifesto (2018) Sweetzerland Manifesto MKII (2023) Aerosmith (1973) Get Your Wings (1974) Toys in the Attic (1975) Rocks...

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Alex Lifeson
Jumat, 2026-06-05 09:37:21

the Alex Lifeson R40 Les Paul Axcess - Rush.com". www.rush.com. "TriAmp MKII Alex Lifeson". Hughes-and-kettner.com. Archived from the original on 25 August...

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Joint Light Tactical Vehicle
Sabtu, 2026-05-30 04:28:15

Procurement (27 March 2025). "Next Generation Fighting Vehicles". www.canada.ca. Retrieved 28 September 2025. "Συνάντηση με Εκπροσώπους Εταιρειών ELBIT SYSTEMS...

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HMS Inflexible (1907)
Kamis, 2025-12-11 04:49:33

armament consisted of a single QF 3-inch (76 mm) 20 cwt AA gun on a high-angle MKII mount at the aft end of the superstructure that was carried from July 1915...

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KF Aerospace
Senin, 2025-09-01 15:16:33

aircraft such as a World War II Mosquito fighter-bomber and a Hawker Tempest MKII. KF launched the passenger charter airline Aeroflyer in 2022, operating with...

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List of radars
Kamis, 2026-05-07 21:32:17

2024. "Spexer 500". Hensoldt AG. Retrieved 2 July 2024. "Spexer 2000 3D MKII". Hensoldt AG. Retrieved 2 July 2024. "TOP STEER CW Radar Kiosk -NEM". Archived...

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Yugoslav Partisans
Minggu, 2026-05-24 09:42:38

Soviet Union and the United Kingdom, including the PPSh-41 and the Sten MKII submachine guns respectively. Additionally, Partisan workshops created their...

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Lola T70
Selasa, 2026-04-07 06:35:07

company, Race Car Replicas, produces an authentic looking replica of both the MkII and MkIIIB T70 using an aluminium monocoque chassis. A South African company...

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Formula One sponsorship liveries
Selasa, 2026-06-02 19:04:27

for a Marlboro-sponsored F1 car. A BRM Type 15 from 1951 season A BRM P30 MKII from the 1953 season The British Racing Partnership privately entered BRM...

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Mushroom Studios
Rabu, 2025-12-24 10:35:56

Retrieved 2025-12-19. Sandy (2025-03-05). "The Rebuilding of the Studer A80 MKII 24 track from Mushroom Studios… the 'Bongo' deck". Reel-to-Reel Tech. Retrieved...

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List of equipment of the Finnish Navy
Rabu, 2026-02-11 09:58:47

European Security & Defence". 2020-02-14. Retrieved 2026-01-20. "DOUBLE EAGLE MKII/MKIII PVDS MINE RECONNAISSANCE VEHICLE" (PDF). "Double Eagle UUVs for Finland's...

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Lensbaby
Selasa, 2025-12-23 01:31:24

Canon-EOS-Bajonett (Brennweite ca. 50 mm) sowie für Minolta, Pentax, Olympus, Contax, Canon FD und M42 (Brennweite ca. 65 mm) erhältlich. "Products: Lenses"...

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Bill Sadler (engineer)
Jumat, 2026-02-27 23:28:59

Collaboration". Muscle Machines. Vaughan, Daniel (April 2008). "1962 Dailu MKII". conceptcarz. Clee, Rich (13 July 1963). "Dailu rebuilt and ready to go"...

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Mecha
Minggu, 2026-06-07 15:52:34

practical hexapod walking harvester. In 2015, Megabots Inc. completed the MKII "Iron Glory" before challenging Kuratas to a duel. In 2017 they completed...

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The White Wires
Sabtu, 2026-04-25 10:49:45

The Band Whose Name Is A Symbol, "Cut Up" Million Dollar Marxists, "Wires MKII" Suppositories, "It's Not Right" The Creeps, "Dance With Me" The Felines...

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List of automobile sales by model
Jumat, 2026-05-15 10:40:27

2014. "Jaguar MkI saloon". Auto Express. Retrieved 4 October 2014. "Jaguar MkII". Auto Express. Retrieved 4 October 2014. "Jaguar XK150". Auto Express. Retrieved...

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List of Indian satellites
Rabu, 2026-05-06 21:32:34

Retrieved 2 March 2020. "HAL hands over 50th set of L-40 stage of GSLV-MKII to ISRO". Zee News. 28 February 2020. Retrieved 2 March 2020. "Starting May...

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List of aircraft shootdowns
Selasa, 2026-06-02 01:37:09

Atlas Impala MKII is shot down by anti-aircraft fire; the pilot survives and is rescued. 12 September 1980 – A South African Atlas Impala MKII from 8th SAAF...

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Nacra F18 Infusion
Sabtu, 2025-12-06 17:56:27

Yachting Magazine (UK). "F18 Infusion MK2". nacra.ca.[permanent dead link] "F18: Nacra Infusion MKII - Catamaran Racing, News & Design". www.catsailingnews...

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Robert W. Ball
Senin, 2026-03-30 09:23:55

Pocket Rowing Skiff Baltic 33 Baltic 37 Baltic 39 Baltic 42 Baltic 51 C&C 25 MKII C&C 26 Wave C&C 27 MK I C&C 27 MK II C&C 27 MK III C&C 27 MK V C&C 3/4 Ton...

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