DOSEN PROFIL LENGKAP

CTNNAL1
Pengidentifikasi
Alias	CTNNAL1, ACRP, CLLP, alpha-CATU, catenin alpha like 1
ID Eksternal	OMIM: 604785; MGI: 1859649; HomoloGene: 2815; GeneCards: CTNNAL1; OMA:CTNNAL1 - orthologs
Lokasi gen (Manusia)
Kr.	Kromosom 9 (manusia)
Akhir	109,013,522 pb
Lokasi gen (Tikus)
Kr.	Kromosom 4 (tikus)
Akhir	56,865,188 pb
Pola ekspresi RNA
	Ekspresi tertinggi di
	right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; Saraf tibialis; ; left ovary; ; left lobe of thyroid gland; ; retinal pigment epithelium; ; right lobe of thyroid gland; ; gastric mucosa; ; cartilage tissue;
	Ekspresi tertinggi di
	transitional epithelium of urinary bladder; ; Badan siliaris; ; retinal pigment epithelium; ; Epithelium of choroid plexus; ; vestibular membrane of cochlear duct; ; endothelial cell of lymphatic vessel; ; tail of embryo; ; prostat; ; lobe of prostate; ; Selaput pelangi;
	Referensi data ekspresi selengkapnya
	Data ekspresi referensi lebih lanjut
Ontologi gen
Fungsi molekuler	actin filament binding; Ikatan protein plasma; cadherin binding;
Komponen seluler	sitoplasma; sitosol; membran sel; Sitoskeleton; membran;
Proses biologis	Adhesi sel; Rho protein signal transduction;
	Sumber:Amigo / QuickGO
Ortologi
	8727
	54366
	ENSG00000119326
	ENSMUSG00000038816
	Q9UBT7
	O88327
	NM_001286974; NM_003798
	NM_018761
	NP_001273903; NP_003789
	NP_061231
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Alpha-catulin adalah protein yang pada manusia dikodekan oleh gen CTNNAL1.^[5]^[6]

Interaksi

CTNNAL1 telah terbukti berinteraksi dengan AKAP13.^[7]

Referensi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119326 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038816 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI (Jan 1999). "Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin". Genomics. 54 (1): 149–54. doi:10.1006/geno.1998.5458. PMID 9806841.
^ "Entrez Gene: CTNNAL1 catenin (cadherin-associated protein), alpha-like 1".
^ Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (Nov 2002). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200. PMID 12270917.

Pranala luar

Lokasi genom CTNNAL1 manusia dan halaman rincian gen CTNNAL1 dalam UCSC Genome Browser.

Bacaan lanjutan

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Janssens B, Staes K, van Roy F (1999). "Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing". Biochim. Biophys. Acta. 1447 (2–3): 341–7. doi:10.1016/s0167-4781(99)00170-0. PMID 10542337.
Demacio PC, Ray PN (2002). "Alpha-catulin maps to the familial dysautonomia region on 9q31". Genome. 44 (6): 990–4. doi:10.1139/gen-44-6-990. PMID 11768226.
Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (2003). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200. PMID 12270917.
Shieh YS, Chang LC, Chiu KC, Wu CW, Lee HS (2003). "Cadherin and catenin expression in mucoepidermoid carcinoma: correlation with histopathologic grade, clinical stage, and patient outcome". J. Oral Pathol. Med. 32 (5): 297–304. doi:10.1034/j.1600-0714.2003.00144.x. PMID 12694354.
Surpili MJ, Delben TM, Kobarg J (2004). "Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1". Biochemistry. 42 (51): 15369–76. doi:10.1021/bi034575v. PMID 14690447.
Merdek KD, Nguyen NT, Toksoz D (2004). "Distinct Activities of the α-Catenin Family, α-Catulin and α-Catenin, on β-Catenin-Mediated Signaling". Mol. Cell. Biol. 24 (6): 2410–22. doi:10.1128/mcb.24.6.2410-2422.2004. PMC 355851. PMID 14993280.

Artikel bertopik gen ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119326 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000038816 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9806841-5] Zhang JS, Nelson M, Wang L, Liu W, Qian CP, Shridhar V, Urrutia R, Smith DI (Jan 1999). "Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin". Genomics. 54 (1): 149–54. doi:10.1006/geno.1998.5458. PMID 9806841.

[entrez-6] "Entrez Gene: CTNNAL1 catenin (cadherin-associated protein), alpha-like 1".

[pmid12270917-7] Park B, Nguyen NT, Dutt P, Merdek KD, Bashar M, Sterpetti P, Tosolini A, Testa JR, Toksoz D (Nov 2002). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200. PMID 12270917.

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CTNNAL1

Interaksi

Referensi

Pranala luar

Bacaan lanjutan

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