CD8
| Putative T-cell surface glycoprotein CD8 | |
|---|---|
| Identifikasi | |
| Simbol | CD8 |
CD8 (cluster of differentiation 8) adalah glikoprotein transmembran yang berfungsi sebagai ko-reseptor untuk reseptor sel T. Seperti reseptor sel T, CD8 mengikat pada molekul major histocompatibility complex (MHC), tetapi CD8 spesifik pada MHC kelas I.[1] Protein ini memiliki dua jenis isoform, yakni alfa dan beta, dan masing-masing disandikan dengan gen yang berbeda. Pada manusia, kedua gen tersebut berada di kromosom 2 di posisi 2p12.
Referensi
- ^ Gao G, Jakobsen B (2000). "Molecular interactions of coreceptor CD8 and MHC class I: the molecular basis for functional coordination with the T-cell receptor". Immunol Today. 21 (12): 630–6. doi:10.1016/S0167-5699(00)01750-3. PMID 11114424.
Pranala luar
- T-cell Group - Cardiff University Diarsipkan 2013-02-18 di Wayback Machine.
- Mouse CD Antigen Chart
- Human CD Antigen Chart
- CD8 alpha - Marker for cytotoxic T lymphocytes [1]
 | Artikel bertopik imunologi ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya. |
- ^ "CD8 alpha - Marker for cytotoxic T lymphocytes". Diarsipkan dari asli tanggal 2015-09-21.
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